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ClinicalTrials.gov public records Last synced Oct 3, 2026, 6:52 PM EDT

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Showing 49–72 of 167 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Cerebral Aneurysms Clear all
Completed Not applicable Interventional Results available

The Penumbra Liberty Trial: Safety and Effectiveness in the Treatment of Wide-Neck Intracranial Aneurysms

NCT01636453
View directory record Official record
Conditions
Wide-neck, Saccular Intracranial Aneurysms
Interventions
Stent assisted coiling with the Liberty Stent
Device
Lead sponsor
Penumbra Inc.
Industry
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
3
States / cities
Denver, Colorado • Chicago, Illinois • Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Aug 23, 2018 · Synced Oct 3, 2026, 6:52 PM EDT
Completed Phase 4 Interventional Results available

PRET: Patients Prone to Recurrence After Endovascular Treatment

NCT00626912
View directory record Official record
Conditions
Intracranial Aneurysm, Subarachnoid Hemorrhage
Interventions
endovascular coil embolization
Procedure
Lead sponsor
Centre hospitalier de l'Université de Montréal (CHUM)
Other
Eligibility
18 Years and older
Enrollment
447 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2015
U.S. locations
18
States / cities
Gainesville, Florida • Kalamazoo, Michigan • Rochester, Minnesota + 15 more
Source: ClinicalTrials.gov public record
Updated Mar 26, 2019 · Synced Oct 3, 2026, 6:52 PM EDT
Recruiting No phase listed Observational

PANTHER Study of Terumo Aortic Knitted and Woven Grafts, and Cardiovascular Patches

NCT04545502
View directory record Official record
Conditions
Aneurysm, Dissection, Aortic Root Aneurysm, Aortic Root Dissection, Carotid Artery Injuries, Aortic Arch, Bypass Extremity Graft, Occlusive Vascular Disease, Aortic Diseases
Interventions
Gelsoft Plus Vascular Graft, Vascular Bypass Graft, Cardiovascular Patch, Gelweave Vascular Graft, Gelweave Valsalva Vascular Graft
Device
Lead sponsor
Vascutek Ltd.
Industry
Eligibility
18 Years and older
Enrollment
2,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2037
U.S. locations
10
States / cities
Aurora, Colorado • Tampa, Florida • Indianapolis, Indiana + 7 more
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Oct 3, 2026, 6:52 PM EDT
Completed Phase 4 Interventional Results available

Seizure Prophylaxis in Aneurysm Repair

NCT01801072
View directory record Official record
Conditions
Intracranial Aneurysms, Seizure
Interventions
Levetiracetam
Drug
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2023
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 29, 2024 · Synced Oct 3, 2026, 6:52 PM EDT
Completed Phase 4 Interventional Results available

MAPS Trial: Matrix And Platinum Science

NCT00396981
View directory record Official record
Conditions
Intracranial Aneurysms
Interventions
Matrix 2® coils for endovascular aneurysm occlusion, GDC® coils for endovascular aneurysm occlusion
Device
Lead sponsor
Stryker Neurovascular
Industry
Eligibility
18 Years to 80 Years
Enrollment
626 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2015
U.S. locations
26
States / cities
Phoenix, Arizona • Tucson, Arizona • New Haven, Connecticut + 23 more
Source: ClinicalTrials.gov public record
Updated Feb 17, 2016 · Synced Oct 3, 2026, 6:52 PM EDT
Suspended Early Phase 1 Interventional Accepts healthy volunteers

Impact of Intranasal Insulin on Sympathetic Activity and Cerebral Vasodilation

NCT05153395
View directory record Official record
Conditions
Healthy, Vasodilation, Insulin Resistance, Autonomic Dysfunction, Obesity
Interventions
Carbon dioxide breathing, Neurovascular Coupling, Human insulin
Other · Drug
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years to 45 Years
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 19, 2025 · Synced Oct 3, 2026, 6:52 PM EDT
Withdrawn Not applicable Interventional

Decision Aids in Cerebral Aneurysm Treatment

NCT02503553
View directory record Official record
Conditions
Cerebral Aneurysm
Interventions
Option grid for cerebral aneurysm treatment, Control
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Feb 3, 2016 · Synced Oct 3, 2026, 6:52 PM EDT
Recruiting No phase listed Observational

International Registry of Intra-arterial and Endosaccular Flow Diverters (IRF)

NCT06174727
View directory record Official record
Conditions
Intracranial Aneurysm
Interventions
Not listed
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years and older
Enrollment
5,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
11
States / cities
Coral Gables, Florida • Jacksonville, Florida • Sarasota, Florida + 8 more
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 3, 2026, 6:52 PM EDT
Terminated Phase 4 Interventional Results available

Treating Patients With Aneurysmal SubArachnoid Hemorrhage (SAH) With Epoetin Alfa

NCT00626574
View directory record Official record
Conditions
Subarachnoid Hemorrhage
Interventions
Epoetin alfa, Saline
Drug
Lead sponsor
University of South Florida
Other
Eligibility
30 Years to 75 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Jul 31, 2018 · Synced Oct 3, 2026, 6:52 PM EDT
Completed Phase 2 Interventional Results available

Safety and Pharmacokinetic Evaluation of Nitrite for Prevention of Cerebral Vasospasm

NCT00873015
View directory record Official record
Conditions
Subarachnoid Hemorrhage
Interventions
Sodium nitrite, Saline
Drug
Lead sponsor
Hope Pharmaceuticals
Industry
Eligibility
18 Years to 80 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated May 21, 2020 · Synced Oct 3, 2026, 6:52 PM EDT
Enrolling by invitation No phase listed Observational

Post-Market Surveillance Study to Evaluate the Long-Term Safety and Effectiveness of the LVIS Device

NCT05453240
View directory record Official record
Conditions
Intracranial Aneurysms
Interventions
Not listed
Lead sponsor
Microvention-Terumo, Inc.
Industry
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Aliso Viejo, California
Source: ClinicalTrials.gov public record
Updated Jun 17, 2025 · Synced Oct 3, 2026, 6:52 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Prospective Randomized Study of Brain Protection During Aortic Arch Replacement

NCT00606190
View directory record Official record
Conditions
Aneurysm of Aortic Arch
Interventions
Retrograde brain perfusion, Antegrade brain perfusion
Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
21 Years to 74 Years
Enrollment
123 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2010
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 17, 2017 · Synced Oct 3, 2026, 6:52 PM EDT
Terminated Phase 2 Interventional Results available

Safety and Efficacy Study of Clevidipine to Control Hypertension in Patients Admitted With Aneurysmal Subarachnoid Hemorrhage

NCT00978822
View directory record Official record
Conditions
Subarachnoid Hemorrhage, Hypertension
Interventions
Clevidipine butyrate injectable emulsion
Drug
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years to 80 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 2, 2023 · Synced Oct 3, 2026, 6:52 PM EDT
Terminated Phase 4 Interventional

HydroCoil Cerebral Aneurysm Treatment Trial

NCT01195129
View directory record Official record
Conditions
Intracerebral Aneursym
Interventions
MicroVention Hydrogel coil, Non-hydrogel coils
Device
Lead sponsor
University of Virginia
Other
Eligibility
21 Years to 90 Years
Enrollment
215 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2015
U.S. locations
11
States / cities
Carmichael, California • Los Angeles, California • Gainesville, Florida + 8 more
Source: ClinicalTrials.gov public record
Updated Dec 12, 2014 · Synced Oct 3, 2026, 6:52 PM EDT
Terminated Phase 4 Interventional Results available

Seizure Prophylaxis in Aneurysm Repair

NCT01974700
View directory record Official record
Conditions
Intracranial Aneurysms, Seizures
Interventions
Levetiracetam
Drug
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Mar 11, 2016 · Synced Oct 3, 2026, 6:52 PM EDT
Recruiting Not applicable Interventional

Pivotal Study of the Silk Vista Baby Flow Diverters in the Treatment of Unruptured Intracranial Aneurysms (PIONEER)

NCT07225075
View directory record Official record
Conditions
Intracranial Aneurysm
Interventions
Silk Vista Baby (SVB) Flow Diverter
Device
Lead sponsor
Balt USA
Industry
Eligibility
22 Years to 80 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
4
States / cities
Thousand Oaks, California • Walnut Creek, California • Jacksonville, Florida + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 23, 2026 · Synced Oct 3, 2026, 6:52 PM EDT
Completed Not applicable Interventional Results available

Pipeline for Uncoilable or Failed Aneurysms

NCT00777088
View directory record Official record
Conditions
Intracranial Aneurysm
Interventions
Pipeline Embolization Device (PED)
Device
Lead sponsor
Medtronic Neurovascular Clinical Affairs
Industry
Eligibility
21 Years to 75 Years
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
8
States / cities
Phoenix, Arizona • Chicago, Illinois • Winfield, Illinois + 5 more
Source: ClinicalTrials.gov public record
Updated Nov 20, 2018 · Synced Oct 3, 2026, 6:52 PM EDT
Completed No phase listed Observational

Brain and Abdominal Aneurysm Study

NCT01420991
View directory record Official record
Conditions
Aneurysm
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
271 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
2
States / cities
Jacksonville, Florida • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 16, 2025 · Synced Oct 3, 2026, 6:52 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Mechanisms of Cerebrovascular Control

NCT02936687
View directory record Official record
Conditions
Metabolic Syndrome X
Interventions
NOS Inhibition, ET-1 Inhibition, NOS Inhibition Placebo, 3 Tesla MRI, Intravenous Catheter, Oral Glucose Tolerance Test, ET-1 Inhibition Placebo
Drug · Device · Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 45 Years
Enrollment
59 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 18, 2021 · Synced Oct 3, 2026, 6:52 PM EDT
Active, not recruiting No phase listed Observational

Florida Cerebrovascular Disease Biorepository and Genomics Center

NCT05491980
View directory record Official record
Conditions
Cerebrovascular Disease, Ischemic Stroke, Transient Ischemic Attack, Intracerebral Hemorrhage, Aneurysmal Subarachnoid Hemorrhage, Vascular Dementia, Anoxic Brain Injury, Unruptured Intracranial Aneurysm, Carotid Artery Stenosis Symptomatic, Asymptomatic Carotid Artery Stenosis, Non-Aneurysmal Perimesencephalic Subarachnoid Haemorrhage, Cerebral Venous Thrombosis, Moyamoya Disease, Fibromuscular Dysplasia, Subarachnoid Hemorrhage, Leukoaraiosis, Arteriovenous Fistula, Reversible Cerebral Vasoconstriction Syndrome, CADASIL
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2030
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Sep 3, 2026 · Synced Oct 3, 2026, 6:52 PM EDT
Recruiting No phase listed Observational

Dome-Only Aneurysm Coiling in Severe Aneurysmal Subarachnoid Hemorrhage

NCT07250958
View directory record Official record
Conditions
Aneurysmal Subarachnoid Hemorrhage
Interventions
Not listed
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated May 11, 2026 · Synced Oct 3, 2026, 6:52 PM EDT
Completed No phase listed Observational

Computed Tomographic (CT) Perfusion and CT Angiography as Screening Tools for Vasospasm Following Subarachnoid Hemorrhage

NCT00962546
View directory record Official record
Conditions
Cerebral Vasospasm, Cerebral Aneurysm, Subarachnoid Hemorrhage
Interventions
Not listed
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 9, 2014 · Synced Oct 3, 2026, 6:52 PM EDT
Withdrawn Phase 1Phase 2 Interventional

Effect of Intraventricular tPA Following Aneurysmal Subarachnoid Hemorrhage

NCT01878136
View directory record Official record
Conditions
Subarachnoid Hemorrhage, Cerebral Vasospasm, Cerebral Aneurysm, Hydrocephalus
Interventions
Tissue Plasminogen Activator
Drug
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 11, 2015 · Synced Oct 3, 2026, 6:52 PM EDT
Active, not recruiting No phase listed Observational

Cerebral Hemodynamics and Microemboli During Placement of Relay®Branch Thoracic Stent-Graft System

NCT05155956
View directory record Official record
Conditions
Thoracic Aortic Aneurysm, Thoracic Aortic Dissection, Microemboli
Interventions
transcranial Doppler ultrasonography (TCD)
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
2
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Oct 3, 2026, 6:52 PM EDT