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ClinicalTrials.gov public records Last synced Oct 12, 2026, 8:41 PM EDT

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Showing 145–168 of 222 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Cerebral Blood Flow Clear all
Terminated Phase 2 Interventional Results available

Augmenting Cerebral Blood Flow to Treat Established Multiple Sclerosis

NCT02466074
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Acetazolamide, Placebo
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 55 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 27, 2023 · Synced Oct 12, 2026, 8:41 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Brain Health in Transgender Adults

NCT07624747
View directory record Official record
Conditions
Gender Dysphoria
Interventions
Magnetic Resonance Imaging, Cognition and Health Tests, Optional Exercise Test
Device · Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 45 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Oct 12, 2026, 8:41 PM EDT
Completed No phase listed Observational

PET Scan to Map the Areas of the Brain Involved in Planning

NCT00001363
View directory record Official record
Conditions
Cognition Disorders
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
Not listed
Enrollment
230 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1993 – 2001
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 12, 2026, 8:41 PM EDT
Completed Phase 3 Interventional Results available

Blood Pressure, Cerebral Blood Flow and Cognition in Spinal Cord Injury

NCT02307565
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Midodrine, Placebo
Drug
Lead sponsor
James J. Peters Veterans Affairs Medical Center
Federal
Eligibility
18 Years to 65 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
2
States / cities
West Orange, New Jersey • The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Feb 21, 2025 · Synced Oct 12, 2026, 8:41 PM EDT
Completed Not applicable Interventional Results available

Arterial Spin Labeling MRI Focal Abnormalities in Refractory Epilepsy

NCT01772654
View directory record Official record
Conditions
Focal Epilepsy
Interventions
Arterial Spin Labeled (ASL) MRI sequence
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 6, 2015 · Synced Oct 12, 2026, 8:41 PM EDT
Not listed Not applicable Interventional

Weathering the Storm: Lung, Heart, and Brain Vascular Rehabilitation for COVID-19

NCT04887272
View directory record Official record
Conditions
Covid19
Interventions
Supervised Exercise Training Protocol, Inspiratory Muscle and Exercise Training
Other
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years to 60 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 14, 2021 · Synced Oct 12, 2026, 8:41 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Magnetic Resonance Imaging Studies of Motor and Thought Processes

NCT00001361
View directory record Official record
Conditions
Cerebrovascular Disorder, Healthy, Movement Disorder, Nervous System Disease, Spinal Cord Injury
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
Not listed
Enrollment
610 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1992 – 2002
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 12, 2026, 8:41 PM EDT
Active, not recruiting No phase listed Observational

Risk Factors and Outcomes of Ischemic Stroke Associated With Tandem or Isolated Cervical Artery Occlusion in Anterior and Posterior Circulation

NCT06965036
View directory record Official record
Conditions
Acute Ischemic Stroke Related to Tandem Occlusion, Acute Ischemic Stroke Due to Isolated Cervical Artery Occlusion
Interventions
Not listed
Lead sponsor
Azienda Unità Sanitaria Locale della Romagna
Other
Eligibility
Not listed
Enrollment
2,880 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Oct 12, 2026, 8:41 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Evaluating Q-Collar Effects on Brain Blood Flow Control During Exercise

NCT06826781
View directory record Official record
Conditions
Healthy
Interventions
Q30 Q-Collar, Not wearing Q-Collar
Device · Other
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 30 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 27, 2025 · Synced Oct 12, 2026, 8:41 PM EDT
Completed No phase listed Observational

MRI Measurement of Brain Metabolism Across the Sleep-Wake Cycle

NCT00117221
View directory record Official record
Conditions
Sleep
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years to 65 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2014
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 5, 2019 · Synced Oct 12, 2026, 8:41 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Cerebral Blood Flow Regulation and Concussions

NCT02754206
View directory record Official record
Conditions
Brain Concussion, Post-Concussion Syndrome
Interventions
Not listed
Lead sponsor
Southern Methodist University
Other
Eligibility
18 Years to 30 Years
Enrollment
79 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Sep 14, 2021 · Synced Oct 12, 2026, 8:41 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Cerebral and Peripheral Perfusion Pilot Study

NCT00751907
View directory record Official record
Conditions
Alzheimer's Disease
Interventions
atorvastatin, Placebo
Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
40 Years to 65 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2007
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Sep 9, 2019 · Synced Oct 12, 2026, 8:41 PM EDT
Withdrawn Phase 1 Interventional Accepts healthy volunteers

Impact of NOS, COX, and ROS Inhibition on Cerebral Blood Flow Regulation

NCT03066115
View directory record Official record
Conditions
Hypoxia, Hypercapnia
Interventions
L-NMMA, Ketorolac, Ascorbic Acid, Intravenous Catheter, Transcranial Doppler Ultrasound
Drug · Procedure
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 45 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jan 10, 2019 · Synced Oct 12, 2026, 8:41 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Enhancement of Cerebral Vasoreactivity and Cognition by Intranasal Insulin in Type 2 Diabetes

NCT01206322
View directory record Official record
Conditions
Type 2 Diabetes Mellitus
Interventions
Intranasal insulin, Placebo
Drug
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
50 Years to 85 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 26, 2019 · Synced Oct 12, 2026, 8:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Study: Diet and Exercise Study to Improve Brain Blood Flow: Blood Flow Improvement Trial

NCT03117829
View directory record Official record
Conditions
PreDiabetes
Interventions
Diet and Exercise
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
45 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 26, 2019 · Synced Oct 12, 2026, 8:41 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Naltrexone and Hypoglycemia in Type 1 Diabetes

NCT01053078
View directory record Official record
Conditions
Type 1 Diabetes, Hypoglycemia Unawareness
Interventions
Naltrexone, Placebo
Drug · Other
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 65 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2014
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 5, 2020 · Synced Oct 12, 2026, 8:41 PM EDT
Completed Not applicable Interventional Results available

Stimulating Neural Activity to Improve Blood Flow and Reduce Amyloid: Path to Clinical Trials

NCT03543878
View directory record Official record
Conditions
Alzheimer Disease
Interventions
Flicker
Device
Lead sponsor
Emory University
Other
Eligibility
50 Years to 90 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 2, 2021 · Synced Oct 12, 2026, 8:41 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Development of a Clinically-relevant Test for Assessment of Cerebral Vascular Function

NCT04336852
View directory record Official record
Conditions
Cerebrovascular Disorders, Cerebrovascular Disease
Interventions
Flow mediated dilation (brachial and femoral arteries), Cerebral vascular reactivity to carbon dioxide (CO2), Cerebral vascular function test
Procedure
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years to 80 Years
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
2
States / cities
Chicago, Illinois • Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated May 20, 2025 · Synced Oct 12, 2026, 8:41 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Development of Techniques for Use in MRI With a Magnetic Field of 7 Tesla

NCT00056914
View directory record Official record
Conditions
Healthy, Magnetic Resonance Imaging
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years and older
Enrollment
102 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2010
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Oct 12, 2026, 8:41 PM EDT
Not yet recruiting Phase 4 Interventional Accepts healthy volunteers

Individual Cerebral Hemodynamic Oxygenation Relationships - ICHOR 4

NCT07103616
View directory record Official record
Conditions
Anesthesia; Reaction, Anesthesia
Interventions
Randomization of Propofol or Dexmedetomidine
Drug
Lead sponsor
Children's Hospital Los Angeles
Other
Eligibility
Up to 7 Years
Enrollment
130 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 5, 2025 · Synced Oct 12, 2026, 8:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Cerebral Blood Flow and tDCS

NCT04033133
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
tDCS
Device
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 65 Years
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Sep 28, 2021 · Synced Oct 12, 2026, 8:41 PM EDT
Withdrawn No phase listed Observational

Noninvasive Monitoring of Cerebral Blood Flow Autoregulation in Patients With Traumatic Brain Injury (TBI)

NCT01605838
View directory record Official record
Conditions
Traumatic Brain Injury (TBI)
Interventions
Not listed
Lead sponsor
Advanced Brain Monitoring, Inc.
Industry
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 14, 2015 · Synced Oct 12, 2026, 8:41 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Statins and Cerebral Blood Flow in Subarachnoid Hemorrhage (SAH)

NCT00795288
View directory record Official record
Conditions
Subarachnoid Hemorrhage
Interventions
Simvastatin, 80 mg/day for 21 days, placebo
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 21, 2016 · Synced Oct 12, 2026, 8:41 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

MRI Biomarkers and Exercise

NCT02729428
View directory record Official record
Conditions
Cerebrovascular Circulation
Interventions
MRI
Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 75 Years
Enrollment
71 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 9, 2019 · Synced Oct 12, 2026, 8:41 PM EDT