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Showing 1–24 of 1,494 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Cerebral Function Clear all
Recruiting Phase 2 Interventional

Personalized Brain Stimulation to Treat Chronic Concussive Symptoms

NCT06073886
View directory record Official record
Conditions
Post-Concussion Syndrome, Concussion, Brain, Mild Traumatic Brain Injury, Head Injury, Headache, Dizziness, Cognitive Symptom, Dysautonomia, Anxiety, Irritability; Syndrome, Depression, Post-traumatic Stress Disorder
Interventions
Active cTBS, Inactive/Sham cTBS, Imaginal exposure
Device · Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 65 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Westwood, Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Feb 23, 2026 · Synced Jun 26, 2026, 2:02 AM EDT
Completed Phase 3 Interventional Results available

Safety and Effectiveness of Two Blood Transfusion Strategies in Surgical Patients With Cardiovascular Disease

NCT00071032
View directory record Official record
Conditions
Anemia, Hematologic Diseases, Cardiovascular Diseases, Heart Diseases, Myocardial Infarction, Thromboembolism, Pneumonia, Cerebrovascular Accident
Interventions
Liberal (10 g/dL) Transfusion Strategy, Restrictive (Symptomatic) Transfusion Strategy
Biological
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
50 Years and older
Enrollment
2,016 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2009
U.S. locations
1
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated Nov 15, 2020 · Synced Jun 26, 2026, 2:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Vasopressin in Intraabdominal Pressure Elevation

NCT03707054
View directory record Official record
Conditions
Intracranial Pressure Increase, Abdominal Compartment Syndrome
Interventions
Study Arm
Diagnostic Test
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 72 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2024
U.S. locations
1
States / cities
Weston, Florida
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Jun 26, 2026, 2:02 AM EDT
Completed Not applicable Interventional Results available

Social Reward and Its Effect on Brain Functions in Psychotherapies for Mid- and Late-Life Depression

NCT04487730
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
"Engage & Connect" Psychotherapy, Symptom Review and Psychoeducation (SRP)
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
50 Years to 85 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 2, 2025 · Synced Jun 26, 2026, 2:02 AM EDT
Terminated Not applicable Interventional

Investigating Effects of High-intensity Gait Training on Gait, Balance and Depression Post-stroke

NCT06373107
View directory record Official record
Conditions
Stroke
Interventions
High intensity gait training
Behavioral
Lead sponsor
Alvernia University
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Allentown, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 10, 2025 · Synced Jun 26, 2026, 2:02 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Effects of Maternal Body Composition on Offspring Brain Structure and Function

NCT01822067
View directory record Official record
Conditions
Brain Function
Interventions
Not listed
Lead sponsor
Arkansas Children's Hospital Research Institute
Other
Eligibility
11 Days to 17 Days
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2026
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Oct 19, 2025 · Synced Jun 26, 2026, 2:02 AM EDT
Recruiting Not applicable Interventional

Effect of a Humanoid Robot With Virtual Reality Games to Train Arm Function in Children With Cerebral Palsy - THRIVE Trial

NCT06881407
View directory record Official record
Conditions
Cerebral Palsy (CP)
Interventions
Robot, Virtual Reality
Device
Lead sponsor
Georgia State University
Other
Eligibility
5 Years to 21 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 17, 2025 · Synced Jun 26, 2026, 2:02 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

In Vivo Imaging of Therapeutic Electric Current Flow

NCT02453763
View directory record Official record
Conditions
Parkinson Disease, Epilepsy, Alzheimer's Disease, Stroke, Autism, Depression, Schizophrenia
Interventions
Transcranial direct current stimulation, MRI
Device · Procedure
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 30 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Apr 4, 2018 · Synced Jun 26, 2026, 2:02 AM EDT
Completed Phase 3 Interventional Results available

PRidopidine's Outcome On Function in Huntington Disease, PROOF- HD

NCT04556656
View directory record Official record
Conditions
Huntington Disease
Interventions
Pridopidine, Placebo
Drug
Lead sponsor
Prilenia
Industry
Eligibility
25 Years and older
Enrollment
499 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
26
States / cities
Davis, California • San Diego, California • Englewood, Colorado + 22 more
Source: ClinicalTrials.gov public record
Updated Mar 11, 2025 · Synced Jun 26, 2026, 2:02 AM EDT
Terminated Phase 2 Interventional Results available

Feasibility Study of Duloxetine in the Treatment of Depression in Patients With Traumatic Brain Injury

NCT01223001
View directory record Official record
Conditions
Traumatic Brain Injury, Depression
Interventions
Duloxetine, Sugar pill
Drug
Lead sponsor
Rehabilitation Hospital of Indiana
Other
Eligibility
18 Years to 75 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1996 – 2011
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Dec 16, 2014 · Synced Jun 26, 2026, 2:02 AM EDT
Recruiting Not applicable Interventional

Determining the Effects of Non-invasive Brain Stimulation to Improve Quadriceps Muscle Function After ACL Reconstruction

NCT07128602
View directory record Official record
Conditions
Anterior Cruciate Ligament Reconstruction Rehabilitation, Quadriceps Muscle Function
Interventions
active transcranial direct current stimulation (tDCS), sham transcranial direct current stimulation (tDCS)
Device
Lead sponsor
Arcadia University
Other
Eligibility
18 Years to 35 Years · Female only
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Glenside, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Jun 26, 2026, 2:02 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Development of a Face Valid Executive Functioning Task

NCT00918112
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Not listed
Lead sponsor
Washington University School of Medicine
Other
Eligibility
20 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2016
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 30, 2022 · Synced Jun 26, 2026, 2:02 AM EDT
Completed No phase listed Observational

Accelerated Transcranial Magnetic Stimulation Intervention for Post-Concussion Syndrome

NCT07211919
View directory record Official record
Conditions
Post Concussive Syndrome, Chronic, Post Concussion Symptoms, Post Concussive Syndrome, Post Concussion Syndrome, Anxiety Disorder Not Otherwise Specified
Interventions
Not listed
Lead sponsor
Cognitive FX
Industry
Eligibility
16 Years to 75 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Provo, Utah
Source: ClinicalTrials.gov public record
Updated Oct 9, 2025 · Synced Jun 26, 2026, 2:02 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Functional Connectivity as a Biomarker of rTMS

NCT03050801
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
rTMS
Device
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years to 50 Years
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 11, 2021 · Synced Jun 26, 2026, 2:02 AM EDT
Completed Not applicable Interventional

Exercise and Activities for Independent Living With Mild Cognitive Impairment (MCI)

NCT00446394
View directory record Official record
Conditions
Mild Cognitive Impairment, Dementia
Interventions
Resources and Activities for Life Long Independence (RALLI), Social Walking program (SW)
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
70 Years and older
Enrollment
181 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 18, 2012 · Synced Jun 26, 2026, 2:02 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Aspirin in Reducing Events in the Elderly

NCT01038583
View directory record Official record
Conditions
Functional Disability, Dementia, Heart Disease, Stroke, Cancer, Bleeding, Depression
Interventions
100 mg enteric-coated aspirin, Placebo
Drug
Lead sponsor
Hennepin Healthcare Research Institute
Other
Eligibility
65 Years and older
Enrollment
19,114 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2024
U.S. locations
33
States / cities
Birmingham, Alabama • Palo Alto, California • Washington D.C., District of Columbia + 26 more
Source: ClinicalTrials.gov public record
Updated Apr 4, 2021 · Synced Jun 26, 2026, 2:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Acute Nerve Stimulation For Enhancing Human and Cognitive Performance

NCT05675956
View directory record Official record
Conditions
Concussion, Mild, Autonomic Nervous System, Cognitive
Interventions
Experimental group with 100% intensity setting on Apollo Neuro device, Active Comparator group with 10% intensity setting on the Apollo Neuro device
Device
Lead sponsor
University of South Carolina
Other
Eligibility
18 Years to 35 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Mar 27, 2024 · Synced Jun 26, 2026, 2:02 AM EDT
Completed No phase listed Observational Results available

BRAIN, Symptoms, and Physical Activity in COPD

NCT04291131
View directory record Official record
Conditions
COPD, Chronic Musculoskeletal Pain
Interventions
Not listed
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
40 Years and older · Male only
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 14, 2025 · Synced Jun 26, 2026, 2:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Peanuts and Neurocognitive / Cardiovascular Health in Black Individuals

NCT06318377
View directory record Official record
Conditions
Cardiovascular Diseases, Hypertension, Cognitive Decline, Diet, Healthy
Interventions
Peanut group
Dietary Supplement
Lead sponsor
The University of Texas at Arlington
Other
Eligibility
18 Years to 50 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Arlington, Texas
Source: ClinicalTrials.gov public record
Updated Mar 31, 2025 · Synced Jun 26, 2026, 2:02 AM EDT
Completed Not applicable Interventional

FES Assisted Cycling in Children With CP

NCT04688424
View directory record Official record
Conditions
Cerebral Palsy Spastic Diplegia
Interventions
FES, Cycling
Device · Other
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
10 Years to 18 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2016
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 29, 2020 · Synced Jun 26, 2026, 2:02 AM EDT
Recruiting Not applicable Interventional

Effect of Neuro20 Functional Electrical Stimulation Suit on Autonomic Function, Muscle Performance, and Gait

NCT07164846
View directory record Official record
Conditions
Spinal Cord Injury, Stroke, Amputees
Interventions
Therapy Sessions
Device
Lead sponsor
Brooks Rehabilitation
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
2
States / cities
Jacksonville, Florida • Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Oct 30, 2025 · Synced Jun 26, 2026, 2:02 AM EDT
Not yet recruiting Phase 2 Interventional

Remotely Administered tDCS to Improve Cognitive Function in Veterans With mTBI and PTSD Principal Investigator

NCT07414537
View directory record Official record
Conditions
Cognition, Brain Injuries, Stress Disorders, Post-Traumatic
Interventions
Transcranial direct current stimulation (tDCS), Cognitive training
Device · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
20 Years to 75 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2030
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 16, 2026 · Synced Jun 26, 2026, 2:02 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Cherries Role in Gut Microbiota-liver-brain Function

NCT05586386
View directory record Official record
Conditions
Obesity
Interventions
Cherry group, Placebo group
Other
Lead sponsor
Texas A&M University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
College Station, Texas
Source: ClinicalTrials.gov public record
Updated Oct 18, 2022 · Synced Jun 26, 2026, 2:02 AM EDT
Recruiting Not applicable Interventional

Brain Stimulation for Foot-sole Sensation in Older Adults With Foot-sole Somatosensory Deficits

NCT06771531
View directory record Official record
Conditions
Somatosensory Function, Balance Control, Mobility
Interventions
transcranial direct current stimulation, active sham stimulation
Device
Lead sponsor
Hebrew SeniorLife
Other
Eligibility
65 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Roslindale, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 21, 2026 · Synced Jun 26, 2026, 2:02 AM EDT