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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Recruiting Not applicable Interventional Accepts healthy volunteers

Transcranial Photobiomodulation in Anxiety Disorders

NCT07133893
Conditions
Symptoms of Anxiety
Interventions
Attention bias assessment and modification, Transcranial photobiomodulation
Behavioral · Device
Lead sponsor
Francisco Gonzalez-Lima, PhD
Other
Eligibility
18 Years to 100 Years
Enrollment
280 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Austin, Texas
Conditions
Traumatic Brain Injury, Intracranial Hypertension
Interventions
Mannitol, Hypertonic Saline
Drug
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 70 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
1
States / cities
San Antonio, Texas
Recruiting No phase listed Observational Accepts healthy volunteers

Individual Cerebral Hemodynamic Oxygenation Relationships (ICHOR 1)

NCT06195345
Conditions
HIE, TBI (Traumatic Brain Injury), TBI, Hemodynamic Instability, Hypoxic-Ischemic Encephalopathy
Interventions
MR Imaging
Diagnostic Test
Lead sponsor
Children's Hospital Los Angeles
Other
Eligibility
1 Minute to 18 Years
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2035
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Intracranial Atherosclerotic Disease, Stroke, Angioplasty, Balloon, Hemodynamics, Device Safety
Interventions
Submaximal balloon angioplasty
Device
Lead sponsor
Case Western Reserve University
Other
Eligibility
30 Years to 90 Years
Enrollment
159 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2032
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Brain Injuries, Intracranial Pressure Increase, Monitoring
Interventions
Intracranial Pressure Noninvasive Monitoring
Device
Lead sponsor
University of Louisville
Other
Eligibility
18 Years to 100 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Louisville, Kentucky
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Metabolic and Hemodynamic Reserve in Pediatric SCA

NCT04406818
Conditions
Child, Only, Brain Diseases, Sickle Cell Disease, Anemia, Sickle Cell
Interventions
Carbon Dioxide
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
4 Years to 21 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
1
States / cities
St Louis, Missouri
Conditions
Mild Cognitive Impairment
Interventions
External Counterpulsation (EECP)
Device
Lead sponsor
Patrick Moriarty, MD, FACP, FACC
Other
Eligibility
18 Years to 85 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Kansas City, Kansas
Conditions
Stroke, Intracranial Stenosis
Interventions
Not listed
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years to 85 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Nashville, Tennessee
Conditions
Birth Asphyxia With Neurologic Involvement
Interventions
Umbilical Cord Milking, Early Cord Clamping
Procedure
Lead sponsor
Sharp HealthCare
Other
Eligibility
35 Weeks to 42 Weeks
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
2
States / cities
San Diego, California
Conditions
Cerebral Microvascular Circulation
Interventions
Mechanical ventilation adjustment
Procedure
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
San Francisco, California
Conditions
Moyamoya, Stroke
Interventions
Not listed
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2015
U.S. locations
1
States / cities
St Louis, Missouri
Conditions
Healthy
Interventions
Pioglitazone, Placebo
Drug
Lead sponsor
Takeda
Industry
Eligibility
55 Years to 83 Years
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Orthostatic Hypotension, Pure Autonomic Failure, Multiple System Atrophy, Autonomic Failure
Interventions
Abdominal compression, Sham abdominal compression, Placebo pill, midodrine
Other · Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2025
U.S. locations
1
States / cities
Nashville, Tennessee
Completed No phase listed Observational Accepts healthy volunteers

Cerebral Anatomy, Hemodynamics and Metabolism

NCT02919956
Conditions
Hypoplastic Left Heart Syndrome
Interventions
Magnetic Resonance Imaging, Neurodevelopmental Testing
Other
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
3 Years and older
Enrollment
121 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Ventricular Tachycardia
Interventions
Data Collection Forms
Other
Lead sponsor
Dhanunjaya Lakkireddy, MD, FACC
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Kansas City, Kansas
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

Biomarker-Led Optimization of Successful Surgical Outcomes in Moyamoya

NCT06634004
Conditions
Moyamoya Disease
Interventions
BOLD MRI
Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 69 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2030
U.S. locations
2
States / cities
Baltimore, Maryland • Nashville, Tennessee
Conditions
Autonomic Failure, Pure Autonomic Failure, Multiple System Atrophy, Parkinson Disease, Supine Hypertension, Neurogenic Orthostatic Hypotension
Interventions
Active CPAP, Sham CPAP, Sleeping in a head-up tilt (HUT) position
Device · Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
40 Years to 80 Years
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Nashville, Tennessee
Conditions
Mechanical Circulatory Support
Interventions
Not listed
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Conditions
Adult Intracranial Tumor, Adult Solid Tumor
Interventions
Remifentanil, Dexmedetomidine
Drug
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 80 Years
Enrollment
142 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
2
States / cities
Cleveland, Ohio
Conditions
Anterior Cerebral Artery Syndrome, Anterior Cerebral Artery Stroke, Acute Ischemic Stroke, Cardioembolic Stroke, Vasogenic Cerebral Edema
Interventions
Transcranial Doppler (TCD) examination
Other
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Richmond, Virginia
Not yet recruiting Phase 4 Interventional Accepts healthy volunteers

Individual Cerebral Hemodynamic Oxygenation Relationships - ICHOR 4

NCT07103616
Conditions
Anesthesia; Reaction, Anesthesia
Interventions
Randomization of Propofol or Dexmedetomidine
Drug
Lead sponsor
Children's Hospital Los Angeles
Other
Eligibility
Up to 7 Years
Enrollment
130 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Atrial Fibrillation
Interventions
non-invasive testing
Procedure
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Dallas, Texas
Conditions
Intracranial Arterial Aneurysm
Interventions
Additional scan time on standard MR angiography
Radiation
Lead sponsor
Lahey Clinic
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Burlington, Massachusetts
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Study of Blood Pressure and Blood Supply to the Brain in Persons With a Spinal Cord Injury.

NCT00248807
Conditions
Orthostatic Hypotension, Spinal Cord Injuries
Interventions
1.25 mg enalaprilat IV, Head up tilt (HUT)
Drug · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2012
U.S. locations
1
States / cities
The Bronx, New York