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ClinicalTrials.gov public records Last synced Nov 4, 2026, 9:40 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 190 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Cerebrospinal Fluid Clear all

Conditions: Perinatal Depression, Chronic Pain
Interventions: No intervention; Other
Lead sponsor: Duke University; Other
Eligibility: 18 Years to 40 Years · Female only
Enrollment: 81 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Healthy Volunteer
Interventions: Not listed
Lead sponsor: National Institute of Allergy and Infectious Diseases (NIAID); NIH
Eligibility: 18 Years to 85 Years
Enrollment: 250 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: Started 2004
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Alzheimer's Disease
Interventions: icosapent ethyl (IPE), gel cap placebo; Drug · Other
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 50 Years to 75 Years
Enrollment: 131 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2023
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Guillain-Barré Syndrome, Miller Fisher Syndrome
Interventions: Not listed
Lead sponsor: Erasmus Medical Center; Other
Eligibility: Not listed
Enrollment: 2,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2024
U.S. locations: 26
States / cities: Phoenix, Arizona • Orange, California • New Haven, Connecticut + 19 more

Conditions: Hydrocephalus
Interventions: Thermal Anisotropy; Device
Lead sponsor: Rhaeos, Inc.; Industry
Eligibility: 5 Years to 80 Years
Enrollment: 145 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Vasospasm, Intracranial, Subarachnoid Hemorrhage
Interventions: Extraventricular Drain, Lumbar Drain; Device
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years to 110 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2027
U.S. locations: 1
States / cities: San Diego, California

Conditions: Epilepsy
Interventions: Not listed
Lead sponsor: National Institute of Neurological Disorders and Stroke (NINDS); NIH
Eligibility: Not listed
Enrollment: 45 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2004 – 2005
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Healthy
Interventions: Bacillus Calmette-Guerin (BCG); Biological
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 55 Years to 80 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Charlestown, Massachusetts

Conditions: Spinal Duraplasty
Interventions: Adherus Dural Sealant System, DuraSeal Exact Dural Sealant System; Device
Lead sponsor: Stryker Craniomaxillofacial; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 94 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2025
U.S. locations: 14
States / cities: Duarte, California • Sacramento, California • Stanford, California + 9 more

Conditions: Infection, Meningitis
Interventions: Not listed
Lead sponsor: IDbyDNA, Inc.; Industry
Eligibility: 0 Years to 17 Years
Enrollment: 71 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 3
States / cities: Orange, California • San Diego, California • Miami, Florida

Conditions: Healthy
Interventions: PF-04995274; Drug
Lead sponsor: Pfizer; Industry
Eligibility: 18 Years to 55 Years
Enrollment: 18 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Hydrocephalus
Interventions: Not listed
Lead sponsor: Johns Hopkins All Children's Hospital; Other
Eligibility: 1 Year to 21 Years
Enrollment: 95 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: St. Petersburg, Florida

Conditions: HIV Infections
Interventions: raltegravir; Drug
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 18 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2011
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Healthy
Interventions: Docosahexaenoic acid (DHA), Eicosapentaenoic acid; Drug
Lead sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA); NIH
Eligibility: 18 Years and older
Enrollment: 97 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2001 – 2008
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: HIV Infections
Interventions: Abacavir sulfate, Amprenavir, Lamivudine, Zidovudine; Drug
Lead sponsor: National Institute of Allergy and Infectious Diseases (NIAID); NIH
Eligibility: 18 Years and older
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Ends 2007
U.S. locations: 1
States / cities: New York, New York

Conditions: Relapsing Multiple Sclerosis, Clinically Isolated Syndrome
Interventions: Ocrelizumab; Drug
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years to 50 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2027
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Herpesviridae Infection, HTLV-I Infection, Multiple Sclerosis, Tropical Spastic Paraparesis, Vasculitis
Interventions: Not listed
Lead sponsor: National Institute of Neurological Disorders and Stroke (NINDS); NIH
Eligibility: 18 Years to 75 Years
Enrollment: 1,388 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1976 – 2010
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Cerebrospinal Fluid Leak
Interventions: Suturable DuraGen™; Device
Lead sponsor: Integra LifeSciences Corporation; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 106 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 3
States / cities: Aurora, Colorado • Jacksonville, Florida • Portland, Oregon

Conditions: Epilepsy, Seizures
Interventions: Perampanel; Drug
Lead sponsor: Carilion Clinic; Other
Eligibility: 18 Years and older
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Roanoke, Virginia

Conditions: Healthy
Interventions: Low dose Regular Insulin, High dose Regular insulin; Drug
Lead sponsor: HealthPartners Institute; Other
Eligibility: 18 Years to 35 Years
Enrollment: 2 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Saint Paul, Minnesota

Conditions: Parkinson Disease
Interventions: Intracerebral Infusion of Autologous Cerebral Spinal Fluid; Device
Lead sponsor: Jeff Elias, MD; Other
Eligibility: 30 Years and older
Enrollment: 4 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018
U.S. locations: 1
States / cities: Charlottesville, Virginia

Conditions: Dementia
Interventions: prazosin hydrochloride, placebo; Drug
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 21 Years and older
Enrollment: 9 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2023
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Hydrocephalus
Interventions: Thermal Anisotropy Measurement Device; Device
Lead sponsor: Rhaeos, Inc.; Industry
Eligibility: 5 Years to 80 Years
Enrollment: 130 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 4
States / cities: Tampa, Florida • Chicago, Illinois • Rolling Meadows, Illinois

Conditions: Healthy Volunteers
Interventions: Clonidine Pill; Drug
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 18 Years and older
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: New York, New York

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CSF/Serum Biomarkers in Predicting PND/Persistent Pain After Cesarean

Collection of Data and Samples From Healthy Donors for Use in Translational Research

Brain Amyloid and Vascular Effects of Eicosapentaenoic Acid

International Guillain-Barré Syndrome Outcome Study

Formative Usability Assessment of Wireless Thermal Anisotropy Devices

Lumbar Drain vs Extraventricular Drain to Prevent Vasospasm in Subarachnoid Hemorrhage

Herpes Virus-6 and Epilepsy

A Pilot Study of the Effects of BCG Immunization on CSF and Blood-based Biomarkers in Older Adults.

Adherus™ Dural Sealant in Spinal Procedures

Pediatric Infectious Disease Precision Medicine Using Sequencing Evaluation of CSF

Study In Healthy Subjects To Evaluate The Changes In The Protein sAPP-Alpha In Cerebrospinal Fluid Following A Single Oral Dose Of PF-04995274

Strata Programmable CSF Shunt Valve Study

Raltegravir Augmentation on Persistent Central Nervous System (CNS) Immunoactivation in Treated HIV-1 Patients

Effect of Polyunsaturated Fatty Acids on Cardiovascular and Motor Responses Under Stress

Four-Drug Combination Therapy With Zidovudine, Lamivudine, 1592U89 (Abacavir), and 141W94 (Amprenavir) in HIV-Infected Patients

Impact of Ocrelizumab on Cerebrospinal Fluid Biomarkers at Multiple Sclerosis Onset

Assessment of Patients With Multiple Sclerosis (MS)

Suturable DuraGen™ PMCF Study

Correlation of Serum Level of Perampanel (PER) Level to Cerebrospinal Fluid (CSF) Levels of PER

Measurement of Insulin Levels in Cerebral Spinal Fluid (CSF) of Healthy Adults After a Single Intranasal Dose

Convection Enhanced Delivery of CSF in DBS for Parkinson's

Prazosin and Cerebrospinal Fluid (CSF) Biomarkers in Mild Traumatic Brain Injury (mTBI)

Longitudinal Measurements of Flow in Cerebrospinal Fluid Shunts With a Wireless Thermal Anisotropy Measurement Device

PET Study of a2a Agonist Effects on the Ventricular CSF Clearance of [11C]Butanol