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Showing 1–24 of 346 matching trials from the live ClinicalTrials.gov search.
Recruiting Not applicable Interventional Accepts healthy volunteers

Imaging Speech in Neurotypical Adults and Individuals With Cerebellar Stroke

NCT06458153
Conditions
Stroke, Cerebellum
Interventions
Neural responses to speech functional localizer, Neural responses to silent articulation, Neural responses to self vs. externally generated speech, Event-related potentials for speech, Neural responses to induced speech errors, Neural responses to sensory-motor adaptation, Speech production behaviors, Auditory acuity testing, Neural responses to learning a non-speech auditory motor behavior
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Completed Early Phase 1 Interventional Accepts healthy volunteers

Blood Brain Flow and Exercise

NCT02653638
Conditions
Cerebrovascular Circulation
Interventions
Control, Indomethacin
Other · Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 75 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Madison, Wisconsin
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

NuroSleeve Powered Brace & Stimulation System to Restore Arm Function

NCT04798378
Conditions
Neurologic Diseases, Hemiparesis, Quadriplegia, Muscular Dystrophies, Arthrogryposis, Spinal Cord Injuries, Charcot-Marie-Tooth, Stroke, Weakness of Extremities as Sequela of Stroke, Weakness Due to Upper Motor Neuron Dysfunction, Amyotrophic Lateral Sclerosis, Spinal Muscular Atrophy, Arm Paralysis, Cerebral Palsy
Interventions
Neurosleeve
Device
Lead sponsor
Thomas Jefferson University
Other
Eligibility
4 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
2
States / cities
Wilmington, Delaware • Philadelphia, Pennsylvania
Conditions
Stroke
Interventions
Noninvasive spinal stimulation with gait training, Conventional gait training, Exploratory Phase - Optimization of Gait Training and Spinal Stimulation
Device · Other
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years and older
Enrollment
115 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Stroke, Occupational Therapy, Activities of Daily Living, Rehabilitation, Virtual Reality
Interventions
VALOR Home Exercise Program (HEP), Usual Care Treatment (UCT) Control
Device · Other
Lead sponsor
Barron Associates, Inc.
Industry
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Not listed Not applicable Interventional

Stroke Recovery and Music or No Music

NCT03608904
Conditions
Ischemic Stroke
Interventions
Music listening, Spoken word (language) listening
Other
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
18 Years to 90 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Houston, Texas
Conditions
Stroke
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years to 80 Years
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Acquired Brain Injury, Traumatic Brain Injury, Stroke
Interventions
Adapted Hatha Yoga, Low-Impact Exercise
Behavioral
Lead sponsor
Colorado State University
Other
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Fort Collins, Colorado
Conditions
Brain Infarction, Brain Ischemia
Interventions
t DC stimulation, tDCStimulation
Device
Lead sponsor
University of Oklahoma
Other
Eligibility
19 Years to 90 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Conditions
Stroke
Interventions
VR immersive therapy
Procedure
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Richmond, Virginia
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Effects of Vibration on Motor Function of Survivors of Chronic Stroke

NCT06663501
Conditions
Stroke, Healthy
Interventions
Assisted Motion with Enhanced Sensation training
Device
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 70 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Right Hemispheric Stroke
Interventions
Aprosodia Intervention, No-Intervention
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 89 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Carotid Stenosis
Interventions
Minocycline, Placebo oral capsule
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 90 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Not applicable Interventional Accepts healthy volunteers Results available

Internet and Telephone Support Intervention for Stroke Caregivers

NCT04348851
Conditions
Depression, Quality of Life, Recovery of Function, Self Efficacy, Stress
Interventions
Caregiver problem-solving, Attention Control
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Gainesville, Florida
Conditions
Stroke, Sleep Wake Disorders, Rehabilitation, Recovery of Function
Interventions
Observation
Other
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
18 Years and older
Enrollment
200 participants
Timeline
2021 – 2025
U.S. locations
6
States / cities
Atlanta, Georgia • Kansas City, Kansas • Syracuse, New York + 1 more
Conditions
Stroke
Interventions
Stroke Rehabilitation
Procedure
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2003
U.S. locations
1
States / cities
Palo Alto, California
Conditions
Stroke, Aphasia
Interventions
tDCS, Speech and language therapy
Device · Behavioral
Lead sponsor
Casa Colina Hospital and Centers for Healthcare
Other
Eligibility
18 Years to 85 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Pomona, California
Conditions
Blood Pressure, Endothelial Dysfunction, Hypertension
Interventions
Inspiratory muscle strength training, Brisk walking
Other
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
50 Years and older
Enrollment
102 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Boulder, Colorado
Completed No phase listed Observational Accepts healthy volunteers

MRI Biomarkers and Exercise

NCT02729428
Conditions
Cerebrovascular Circulation
Interventions
MRI
Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 75 Years
Enrollment
71 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Madison, Wisconsin
Conditions
Stroke, Brain Disease, Central Nervous System Diseases, Nervous System Diseases, Cardiovascular Diseases
Interventions
Deep Brain Stimulation (DBS) of the Motor Thalamus
Device
Lead sponsor
Jorge Gonzalez-Martinez
Other
Eligibility
18 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Stroke, Cerebrovascular Disorders, Brain Diseases, Central Nervous System Diseases, Nervous System Diseases, Vascular Diseases, Cardiovascular Diseases
Interventions
Aerobic Exercise, Upper Extremity Repetitive Task Practice
Behavioral
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 85 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Cognitive Decline
Interventions
Not listed
Lead sponsor
Lahey Clinic
Other
Eligibility
50 Years and older
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2017
U.S. locations
1
States / cities
Burlington, Massachusetts
Completed Early Phase 1 Interventional Accepts healthy volunteers

Imaging Laterality in Chronic Stroke Patients

NCT03584425
Conditions
Stroke, Motor Cortex; Lesion
Interventions
Rasch modified version of the Fugl-Meyer Motor assessment, Anatomical image acquisition, Functional MRI task and acquisition
Diagnostic Test
Lead sponsor
Medical University of South Carolina
Other
Eligibility
21 Years to 80 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
Charleston, South Carolina
Conditions
Stroke
Interventions
Surface functional electrical stimulation (FES), Motor learning, Brain computer interface (BCI) training
Other
Lead sponsor
Louis Stokes VA Medical Center
Federal
Eligibility
22 Years and older
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2016
U.S. locations
1
States / cities
Gainesville, Florida