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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Cervical Ripening Clear all
Terminated Not applicable Interventional Results available

Cervical Ripening in Postmenopausal Women

NCT02534883
View directory record Official record
Conditions
Stenosis of Cervix
Interventions
Misoprostol, Placebo
Drug
Lead sponsor
St. Louis University
Other
Eligibility
45 Years to 85 Years · Female only
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 11, 2018 · Synced Jun 10, 2026, 12:17 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mifepristone Versus Laminaria for Cervical Ripening in Midtrimester Induction

NCT00383032
View directory record Official record
Conditions
Abortion, Induced
Interventions
mifepristone
Drug
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
16 Years and older · Female only
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2006
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Oct 23, 2023 · Synced Jun 10, 2026, 12:17 AM EDT
Completed Not applicable Interventional Results available

Foley Bulb With Oral Misoprostol for Induction of Labor

NCT03407625
View directory record Official record
Conditions
Pregnancy, Labor, Induced
Interventions
Foley bulb plus Oral Misoprostol, Oral Misoprostol
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
10 Years and older · Female only
Enrollment
2,227 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Nov 3, 2020 · Synced Jun 10, 2026, 12:17 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Randomized Control Trial of Intracervical Balloon Placement vs Oxytocin in Women With Term PROM and Unripe Cervices

NCT03172858
View directory record Official record
Conditions
Premature Rupture of Membrane, Unfavorable Cervix
Interventions
Intracervical balloon catheter, Oxytocin
Device · Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 50 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 25, 2024 · Synced Jun 10, 2026, 12:17 AM EDT
Completed Not applicable Interventional

Adjuvant Oxytocin for Preinduction Ripening With a Foley catheter--a Clinical Trial

NCT00468520
View directory record Official record
Conditions
Pregnancy, Induced Labor, Cervical Ripening
Interventions
low dose oxytocin
Drug
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2005
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 1, 2011 · Synced Jun 10, 2026, 12:17 AM EDT
Withdrawn Phase 2 Interventional Accepts healthy volunteers

Pharmacokinetics and Safety of the 100 Mcg Misoprostol Vaginal Insert (MVI 100)

NCT00528255
View directory record Official record
Conditions
Cervical Ripening, Induction of Labor
Interventions
Misoprostol Vaginal Insert (MVI 100)
Drug
Lead sponsor
Ferring Pharmaceuticals
Industry
Eligibility
18 Years and older · Female only
Healthy volunteers
Accepts healthy volunteers
U.S. locations
6
States / cities
Phoenix, Arizona • Long Beach, California • Orange, California + 3 more
Source: ClinicalTrials.gov public record
Updated Jun 17, 2012 · Synced Jun 10, 2026, 12:17 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Outpatient Cervical Ripening With Orally Administered Misoprostol in Diabetics

NCT00514618
View directory record Official record
Conditions
Diabetes, Gestational
Interventions
Misoprostol, Placebo
Drug · Dietary Supplement
Lead sponsor
MemorialCare Health System
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2008
U.S. locations
1
States / cities
Long Beach, California
Source: ClinicalTrials.gov public record
Updated Nov 6, 2023 · Synced Jun 10, 2026, 12:17 AM EDT
Terminated Not applicable Interventional Results available

Prehospital Cervical Ripening Before Induction and the Maternal Experience

NCT01641601
View directory record Official record
Conditions
Labor, Induced, Cervical Ripening
Interventions
Outpatient transcervical Foley balloon
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
15 Years to 50 Years · Female only
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 4, 2020 · Synced Jun 10, 2026, 12:17 AM EDT
Recruiting Not applicable Interventional

Cervical Ripening Balloons for Same-Day Cervical Prep

NCT06964373
View directory record Official record
Conditions
Dilation and Evacuation
Interventions
Cervical Ripening Balloon, Osmotic Dilators
Device
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years and older · Female only
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Jun 10, 2026, 12:17 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Tension Versus Tension- Free Foley Balloon for Cervical Ripening

NCT05404776
View directory record Official record
Conditions
Induced Vaginal Delivery
Interventions
Placement of Foley balloon for cervical ripening with tension., Placement of Foley balloon for cervical ripening without tension.
Other
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
279 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 5, 2025 · Synced Jun 10, 2026, 12:17 AM EDT
Completed Phase 4 Interventional Results available

Misoprostol Dosing in BMI Greater Than 30

NCT05262738
View directory record Official record
Conditions
Pregnancy Related, Obesity, Labor Onset and Length Abnormalities
Interventions
50 Micrograms Vaginal Misoprostol (Intervention), 25 Micrograms Vaginal Misoprostol (Control)
Drug
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years and older · Female only
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jul 2, 2024 · Synced Jun 10, 2026, 12:17 AM EDT
Completed Not applicable Interventional

Outpatient Foley For Starting Induction of Labor at Term in Nulliparous Women

NCT03472937
View directory record Official record
Conditions
Pregnancy Related
Interventions
Transcervical Foley catheter placement for cervical ripening
Procedure
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older · Female only
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Feb 5, 2020 · Synced Jun 10, 2026, 12:17 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Patient Satisfaction During Outpatient Versus Inpatient Foley Catheter Induction of Labor

NCT02975167
View directory record Official record
Conditions
Induction of Labor Affected Fetus / Newborn, Cervical Ripening, Patient Satisfaction
Interventions
Outpatient Cervical Ripening, Inpatient Cervical Ripening, Foley catheter placement, Pre-Foley Questionnaire, Post-Foley Questionnaire, Fetal Non-Stress Test
Other · Procedure · Behavioral
Lead sponsor
MemorialCare Health System
Other
Eligibility
18 Years and older · Female only
Enrollment
94 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2025
U.S. locations
1
States / cities
Long Beach, California
Source: ClinicalTrials.gov public record
Updated Jul 22, 2025 · Synced Jun 10, 2026, 12:17 AM EDT
Completed No phase listed Observational

Outpatient Cervical Ripening

NCT04041687
View directory record Official record
Conditions
Pregnancy
Interventions
Not listed
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
Female only
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 29, 2024 · Synced Jun 10, 2026, 12:17 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Foley Balloon Study for Cervical Ripening - Cost Comparison Between Outpatient and Inpatient Cervical Ripening

NCT05506631
View directory record Official record
Conditions
Pregnancy Outcome
Interventions
Outpatient Foley balloon placement, Inpatient Foley Balloon placement
Procedure
Lead sponsor
Lehigh Valley Hospital
Other
Eligibility
18 Years to 39 Years · Female only
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Allentown, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 30, 2025 · Synced Jun 10, 2026, 12:17 AM EDT
Recruiting Not applicable Interventional

RCT of Cervical Ripening Double Ballon Catheter Prior to Dilation and Evacuation.

NCT07200115
View directory record Official record
Conditions
Cervical Preparation Prior to Dilation and Evacuation
Interventions
Cervical Ripening Double Balloon (CRDB) Catheter, Osmotic Dilators
Device
Lead sponsor
Yale University
Other
Eligibility
18 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 4, 2026 · Synced Jun 10, 2026, 12:17 AM EDT
Completed No phase listed Observational

Labor Induction With Oral Versus Vaginal Misoprostol

NCT04755218
View directory record Official record
Conditions
Pregnancy, Labor, Induced
Interventions
Not listed
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
10 Years and older · Female only
Enrollment
2,546 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Apr 4, 2024 · Synced Jun 10, 2026, 12:17 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Inpatient Versus Outpatient Foley Cervical Ripening Study

NCT03725397
View directory record Official record
Conditions
Induced; Birth
Interventions
Outpatient, Inpatient
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older · Female only
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
2
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 21, 2023 · Synced Jun 10, 2026, 12:17 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Inpatient Versus Outpatient Cervical Ripening

NCT03769610
View directory record Official record
Conditions
Pregnancy Related, Labor, Induction, Cervical Ripening
Interventions
Inpatient Foley catheter, Outpatient Foley catheter
Other
Lead sponsor
LifeBridge Health
Other
Eligibility
14 Years to 45 Years · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
2
States / cities
Baltimore, Maryland • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 13, 2021 · Synced Jun 10, 2026, 12:17 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Misoprostol Versus Dilapan-S for Cervical Preparation

NCT00835731
View directory record Official record
Conditions
Cervical Ripening
Interventions
misoprostol, Dilapan-S, vitamin B-12
Drug · Device
Lead sponsor
Planned Parenthood League of Massachusetts
Other
Eligibility
18 Years and older · Female only
Enrollment
125 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 22, 2017 · Synced Jun 10, 2026, 12:17 AM EDT
Completed Phase 3 Interventional Results available

Efficacy & Safety Study Comparing Misoprostol Vaginal Insert (MVI) Versus Dinoprostone Vaginal Insert (DVI) for Reducing Time to Vaginal Delivery

NCT01127581
View directory record Official record
Conditions
Reducing Time to Vaginal Delivery, Cervical Ripening, Induction of Labor
Interventions
MVI 200, Dinoprostone Vaginal Insert (DVI)
Drug
Lead sponsor
Ferring Pharmaceuticals
Industry
Eligibility
18 Years and older · Female only
Enrollment
1,358 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
34
States / cities
Phoenix, Arizona • Scottsdale, Arizona • Tucson, Arizona + 28 more
Source: ClinicalTrials.gov public record
Updated Apr 30, 2014 · Synced Jun 10, 2026, 12:17 AM EDT
Completed Phase 3 Interventional Results available

Safety/Efficacy Study Comparing the Misoprostol Vaginal Insert to Cervidil for Cervical Ripening and Induction of Labor

NCT00308711
View directory record Official record
Conditions
Cervical Ripening, Labor, Induced
Interventions
Misoprostol vaginal insert 100 mcg, Misoprostol vaginal insert 50 mcg, Dinoprostone vaginal insert (Cervidil)
Drug
Lead sponsor
Ferring Pharmaceuticals
Industry
Eligibility
18 Years and older · Female only
Enrollment
1,308 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
49
States / cities
Birmingham, Alabama • Mesa, Arizona • Phoenix, Arizona + 43 more
Source: ClinicalTrials.gov public record
Updated Jun 24, 2012 · Synced Jun 10, 2026, 12:17 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Patient Satisfaction of Cervical Ripening in an Outpatient Setting

NCT01605474
View directory record Official record
Conditions
Pregnancy
Interventions
Patient discharged home after foley bulb placement., Inpatient
Other
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
800 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2012
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 24, 2012 · Synced Jun 10, 2026, 12:17 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Study of the Effectiveness of Cervical Ripening Balloon With and Without Oxytocin

NCT03138252
View directory record Official record
Conditions
Cervical Ripening, Induction of Labor, Multiparity
Interventions
Oxytocin
Drug
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 3, 2022 · Synced Jun 10, 2026, 12:17 AM EDT