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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Cervicalgia Clear all
Completed Not applicable Interventional

Effects of Cervical Manual Therapy on Cervicogenic Headache

NCT03385889
View directory record Official record
Conditions
Unilateral Headache, Musculoskeletal Neck Pain
Interventions
Cervical Spine Mobilization, Cervical Spine Manipulation
Procedure
Lead sponsor
Shenandoah University
Other
Eligibility
18 Years to 70 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Winchester, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 3, 2019 · Synced Sep 23, 2026, 8:15 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Comparison of Manual Assessment of Cervical Segmental Motion With Musculoskeletal Ultrasound

NCT07722676
View directory record Official record
Conditions
Neck Pain
Interventions
Passive Intervertebral Motion testing
Diagnostic Test
Lead sponsor
Florida Gulf Coast University
Other
Eligibility
18 Years to 65 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Fort Myers, Florida
Source: ClinicalTrials.gov public record
Updated Jul 26, 2026 · Synced Sep 23, 2026, 8:15 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Quantitative Ultrasound Biomarkers to Assess Upper Trapezius Muscles in Patients With Chronic Pain

NCT05497622
View directory record Official record
Conditions
Chronic Neck Pain
Interventions
Quantitative Ultrasound, Osteopathic TART Assessment, Osteopathic Manipulation Treatment
Diagnostic Test · Procedure
Lead sponsor
Rocky Vista University, LLC
Other
Eligibility
18 Years and older
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Ivins, Utah
Source: ClinicalTrials.gov public record
Updated Aug 24, 2022 · Synced Sep 23, 2026, 8:15 PM EDT
Completed Not applicable Interventional

Effect of Osteopathic Manipulative Medicine on Motor Function and Quality of Life in Cervical Dystonia

NCT02420106
View directory record Official record
Conditions
Cervical Dystonia
Interventions
Osteopathic Manipulative Medicine
Procedure
Lead sponsor
New York Institute of Technology
Other
Eligibility
2 Years to 100 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Old Westbury, New York
Source: ClinicalTrials.gov public record
Updated Jul 1, 2019 · Synced Sep 23, 2026, 8:15 PM EDT
Completed Not applicable Interventional Results available

Development of STEPPT

NCT06835439
View directory record Official record
Conditions
Pain, Back Pain, Low Back Pain, Chronic Pain, Neck Pain
Interventions
STEPPT Pilot, Standard Care (Control)
Behavioral
Lead sponsor
San Diego State University
Other
Eligibility
18 Years and older
Enrollment
144 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated May 10, 2026 · Synced Sep 23, 2026, 8:15 PM EDT
Completed Not applicable Interventional

Using fMRI to Determine if Cerebral Hemodynamic Responses to Pain Change Following Thoracic Spine Manipulation in Individuals With Mechanical Neck Pain

NCT01862705
View directory record Official record
Conditions
Neck Pain
Interventions
Thoracic spine manipulation
Other
Lead sponsor
OSF Healthcare System
Other
Eligibility
18 Years to 60 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Peoria, Illinois
Source: ClinicalTrials.gov public record
Updated May 12, 2015 · Synced Sep 23, 2026, 8:15 PM EDT
Not listed Phase 4 Interventional

Study on Magnetic Field Therapy to Improve Quality of Sleep and Reduction of Chronic Spine Pain

NCT00445133
View directory record Official record
Conditions
Back Pain, Neck Pain, Sleep Initiation and Maintenance Disorders
Interventions
Magnetic Sleep Pad
Device
Lead sponsor
Weintraub, Michael I., MD, FACP, FAAN
Individual
Eligibility
18 Years to 85 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007
U.S. locations
1
States / cities
Briarcliff Manor, New York
Source: ClinicalTrials.gov public record
Updated Sep 26, 2007 · Synced Sep 23, 2026, 8:15 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Dry Needling vs Dry Needling With ES in Patients With Neck/Shoulder Pain

NCT03638388
View directory record Official record
Conditions
Myofascial Pain, Neck Pain, Shoulder Pain
Interventions
Dry needling (DN), Dry needling with intramuscular electrical stimulation (DNES)
Procedure
Lead sponsor
Kindyle Brennan
Other
Eligibility
18 Years to 60 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Belton, Texas
Source: ClinicalTrials.gov public record
Updated Mar 24, 2019 · Synced Sep 23, 2026, 8:15 PM EDT
Completed Not applicable Interventional

Specific and Shared Mechanisms Associated With Treatment for Chronic Neck Pain

NCT05940012
View directory record Official record
Conditions
Chronic Neck Pain
Interventions
Manual Therapy
Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Nov 17, 2025 · Synced Sep 23, 2026, 8:15 PM EDT
Active, not recruiting Not applicable Interventional

Partners4Pain & Wellbeing: A Randomized Trial of Community Supported Complementary and Integrative Health Self-management for Back Pain

NCT06696352
View directory record Official record
Conditions
Chronic Pain, Back Pain, Neck Pain, Self-management, Complementary Therapies
Interventions
Partners4Pain, Keys to Wellbeing
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
376 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated May 11, 2026 · Synced Sep 23, 2026, 8:15 PM EDT
Not listed No phase listed Observational

Observational Study of the Impact of Genetic Testing on Healthcare Decisions and Care in Interventional Pain Management

NCT02485795
View directory record Official record
Conditions
Pain, Chronic Pain, Back Pain, Nociceptive Pain, Neuropathic Pain, Musculoskeletal Pain, Neck Pain, Pain, Intractable
Interventions
Observational
Other
Lead sponsor
Proove Bioscience, Inc.
Industry
Eligibility
18 Years and older
Enrollment
50,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
31
States / cities
Prescott, Arizona • Heber Springs, Arkansas • Beverly Hills, California + 24 more
Source: ClinicalTrials.gov public record
Updated May 31, 2017 · Synced Sep 23, 2026, 8:15 PM EDT
Completed Phase 4 Interventional

Use of ThermaCare Heat Wraps and Ibuprofen as an Adjunct to Physical Therapy for Neck Pain

NCT02327338
View directory record Official record
Conditions
Heat, Pain
Interventions
thermacare heat wraps, Ibuprofen
Device · Drug
Lead sponsor
Future Sciene Technology
Industry
Eligibility
18 Years to 80 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Henderson, Nevada
Source: ClinicalTrials.gov public record
Updated Jul 31, 2017 · Synced Sep 23, 2026, 8:15 PM EDT
Completed Not applicable Interventional

Collar Use for Cervical Radicular Pain

NCT04163939
View directory record Official record
Conditions
Cervical Radiculopathy
Interventions
Vista Therapy Collar, Placebo
Other
Lead sponsor
Rhode Island Hospital
Other
Eligibility
18 Years and older
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jan 30, 2023 · Synced Sep 23, 2026, 8:15 PM EDT
Completed Not applicable Interventional

Effect of Biofreeze® Versus Placebo on Acute Neck Pain, Disability, and Range of Motion

NCT03157349
View directory record Official record
Conditions
Acute Pain, Neck Pain
Interventions
Biofreeze, Placebo
Other
Lead sponsor
Sport and Spine Rehab Clinical Research Foundation
Other
Eligibility
18 Years to 65 Years
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Landover, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 31, 2019 · Synced Sep 23, 2026, 8:15 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Individually Tailored Yoga Program for the Treatment of Chronic Neck and Back Pain

NCT02806323
View directory record Official record
Conditions
Neck Pain Musculoskeletal, Back Pain, Unspecified
Interventions
Yoga practice
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
30 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jan 25, 2017 · Synced Sep 23, 2026, 8:15 PM EDT
Active, not recruiting Not applicable Interventional

Validating a Clinical Prediction Rule to Guide Manual Therapy and Exercise for Neck Pain Relief

NCT06906107
View directory record Official record
Conditions
Neck Pain Musculoskeletal, Neck Pain Treatment, Cervicalgia
Interventions
Cervical Manipulation, Exercise, Mobilization
Procedure
Lead sponsor
Baylor University
Other
Eligibility
18 Years to 70 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
4
States / cities
Rochester, Minnesota • Syracuse, New York • Waco, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 13, 2026 · Synced Sep 23, 2026, 8:15 PM EDT
Terminated Phase 1 Interventional

Pilot Study of Spinal Manipulation for Chronic Neck Pain

NCT00030004
View directory record Official record
Conditions
Neck Pain
Interventions
spinal manipulation, midazolam
Procedure · Drug
Lead sponsor
National Center for Complementary and Integrative Health (NCCIH)
NIH
Eligibility
18 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2001
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Aug 17, 2006 · Synced Sep 23, 2026, 8:15 PM EDT
Completed Not applicable Interventional

Cervical and Upper Thoracic Mobilization and Manipulation for Mechanical Neck Pain

NCT02036905
View directory record Official record
Conditions
Neck Pain
Interventions
Cervical and thoracic mobilization, cervical and thoracic manipulation
Other
Lead sponsor
Youngstown State University
Other
Eligibility
18 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
2
States / cities
Solon, Ohio • Havertown, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 25, 2016 · Synced Sep 23, 2026, 8:15 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Influence of Directional Preference on Movement Coordination Deficits in Individuals With Whiplash Associated Disorders

NCT06143228
View directory record Official record
Conditions
Whiplash Injury of Cervical Spine, Muscle Weakness
Interventions
Not listed
Lead sponsor
D'Youville College
Other
Eligibility
19 Years to 70 Years
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
2
States / cities
Tallahassee, Florida • Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Feb 21, 2024 · Synced Sep 23, 2026, 8:15 PM EDT
Recruiting Phase 3 Interventional

CARES (Comprehensive Analgesic, Recovery, and Education Support) for Surgery Trial

NCT06027099
View directory record Official record
Conditions
Chronic Pain, Back Pain, Neck Pain, Opioid Misuse
Interventions
Tizanidine, MI-Opioid Taper, Placebo, Enhanced Usual Care
Drug · Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 75 Years
Enrollment
375 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
4
States / cities
Stanford, California • Kansas City, Kansas • Boston, Massachusetts + 1 more
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Sep 23, 2026, 8:15 PM EDT
Completed Phase 3 Interventional Results available

Study to Evaluate the Long-Term Safety of Hydrocodone Bitartrate Extended-Release Tablets (CEP-33237) in Patients Who Require Opioid Treatment for an Extended Period of Time

NCT01223365
View directory record Official record
Conditions
Chronic Pain
Interventions
Hydrocodone ER
Drug
Lead sponsor
Teva Branded Pharmaceutical Products R&D, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
330 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
54
States / cities
Mobile, Alabama • Anaheim, California • Beverly Hills, California + 46 more
Source: ClinicalTrials.gov public record
Updated Jun 4, 2017 · Synced Sep 23, 2026, 8:15 PM EDT
Active, not recruiting Not applicable Interventional

EMVITAL + EMFACE Combination Therapy for Temporomandibular Joint (TMJ) Pain Relief

NCT07661121
View directory record Official record
Conditions
Temporomandibular Disorder (TMD), Temporomandibular Joint Pain, Facial Pain, Neck Pain
Interventions
Treatment with BTL-043 and BTL-785F
Device
Lead sponsor
BTL Industries Ltd.
Industry
Eligibility
22 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
4
States / cities
Leesburg, Florida • Ocala, Florida • Covington, Kentucky + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 21, 2026 · Synced Sep 23, 2026, 8:15 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Neuroendocrine Changes in Cervical Spinal Manipulation and Mobilization Non-specific Mechanical Neck Pain

NCT04911608
View directory record Official record
Conditions
Neck Pain
Interventions
cervical spinal manipulation, cervical spinal mobilization
Other
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years to 60 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Jan 19, 2023 · Synced Sep 23, 2026, 8:15 PM EDT
Recruiting Not applicable Interventional

Psychological Options for Wellness and Recovery (POWeR) Trial for Veterans With Chronic Back/Neck Pain

NCT07137715
View directory record Official record
Conditions
Chronic Pain, Back Pain, Back Pain Lower Back Chronic, Neck Pain
Interventions
Pain reprocessing therapy (PRT), Cognitive Behavioral Therapy for Chronic Pain (CBT-CP), Usual Care
Behavioral · Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years and older
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Sep 23, 2026, 8:15 PM EDT