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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Completed Not applicable Interventional Accepts healthy volunteers Results available

Chlorhexidine-Alcohol Versus Povidone-Iodine for Cesarean Antisepsis

NCT02202577
Conditions
Surgical Site Infection
Interventions
Chlorhexidine - Isopropyl alcohol, Povidone-Iodine Scrub and Paint
Drug
Lead sponsor
Case Western Reserve University
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
932 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Cleveland, Ohio
Completed Not applicable Interventional Accepts healthy volunteers

PROPHYLACTIC ANTIBIOTICS PRIOR TO CESAREAN SECTION IN OBESE WOMEN

NCT01810354
Conditions
Infection Prevention
Interventions
Cefazolin
Drug
Lead sponsor
Women and Infants Hospital of Rhode Island
Other
Eligibility
Female only
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Providence, Rhode Island
Conditions
Surgical Site Infection
Interventions
Chlorhexidine-alcohol group, Povidone-Iodine Group
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 45 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Bacterial Vaginoses
Interventions
Metronidazole, Placebo
Drug
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Columbus, Ohio
Conditions
Wound Infection, Complication, Postoperative
Interventions
Povidone Iodine, Chlorhexidine gluconate
Procedure
Lead sponsor
Richmond University Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
1,114 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Staten Island, New York
Completed Not applicable Interventional Accepts healthy volunteers

Cesarean Skin Incision Trial

NCT01897376
Conditions
Wound Complication
Interventions
Pfannenstiel incision, vertical skin incision
Procedure
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
228 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
2
States / cities
Galveston, Texas • Houston, Texas
Conditions
Cesarean Delivery, Wound Infection, Obesity
Interventions
cefazolin
Drug
Lead sponsor
Michael Stitely
Other
Eligibility
18 Years and older · Female only
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Morgantown, West Virginia
Completed Not applicable Interventional Results available

Negative Pressure Wound Therapy After Cesarean Delivery

NCT01637870
Conditions
Major Puerperal Infection, Postpartum, Wound Complications, Wound Seroma, Caesarean Section Wound Separation, Wound Infection
Interventions
Prevena negative pressure wound system
Device
Lead sponsor
Abbey Hardy-Fairbanks
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Iowa City, Iowa
Completed Phase 4 Interventional Results available

Subcuticular Suture for Cesarean Skin Incision Closure

NCT02459093
Conditions
Complications; Cesarean Section, Surgical Wound Infection
Interventions
poliglecaprone 25 suture, polyglactin 910 suture
Device
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
550 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
2
States / cities
The Bronx, New York
Conditions
Obesity, Morbid, Wound Infection, Wound Complication
Interventions
Negative pressure wound therapy (PREVENA Incision Management Therapy System), Standard dressing
Device
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Recruiting Phase 3 Interventional Accepts healthy volunteers

Azithromycin Prophylaxis for PRElabor CEsarean DElivery Trial

NCT06605118
Conditions
Obstetrical Complications, Labor and Delivery Complication, Cesarean Delivery
Interventions
Azithromycin Injection, Placebo, Standard of Care Preoperative antibiotics
Drug
Lead sponsor
The George Washington University Biostatistics Center
Other
Eligibility
Female only
Enrollment
8,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
14
States / cities
Birmingham, Alabama • San Francisco, California • Chicago, Illinois + 10 more
Conditions
Cesarean Section, Endometritis, Surgical Wound Infection
Interventions
Vaginal cleansing before cesarean delivery
Procedure
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older · Female only
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
3
States / cities
Indianapolis, Indiana
Conditions
Endometritis, Wound Infection, Abscess, Surgical Site Infection
Interventions
Azithromycin and standard of care, Placebo and standard of care
Drug
Lead sponsor
Alan Tita
Other
Eligibility
14 Years and older · Female only
Enrollment
2,013 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
9
States / cities
Birmingham, Alabama • New Orleans, Louisiana • Jackson, Mississippi + 6 more
Conditions
Post-operative Complications, Surgical Site Infection, Surgical Wound Infection
Interventions
Prevena™ Incision Management System (PIMS), Standard-of-care Dressing
Device
Lead sponsor
KCI USA, Inc
Industry
Eligibility
18 Years and older · Female only
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Cesarean Section, Surgical Site Infection, Wound Dehiscence, Seroma
Interventions
Steri-Strip™ Skin Closures, Standard Cesarean Wound Closure
Device · Procedure
Lead sponsor
Riverside University Health System Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
610 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Moreno Valley, California
Completed Not applicable Interventional Accepts healthy volunteers

Timing of Prophylactic Antibiotics for Cesarean Sections

NCT00330278
Conditions
Endometritis, Wound Infection
Interventions
Cefazolin
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older · Female only
Enrollment
350 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2006
U.S. locations
1
States / cities
Charleston, South Carolina
Terminated Phase 4 Interventional Results available

Antibacterial-coated Sutures at Time of Cesarean

NCT03386240
Conditions
Surgical Site Infection, Surgical Wound Infection, Cesarean Section; Infection, Cesarean Section Complications
Interventions
Vicryl-plus, monocryl-plus, PDS-plus (Triclosan-coated Sutures), Vicryl, monocryl, PDS (not coated with triclosan)
Drug · Other
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
1,169 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Galveston, Texas
Conditions
Surgical Wound Dehiscence, Wound Infection
Interventions
Negative pressure wound closure, Standard wound closure
Procedure
Lead sponsor
West Virginia University
Other
Eligibility
18 Years and older · Female only
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
2
States / cities
Charleston, West Virginia • Morgantown, West Virginia
Conditions
Surgical Site Infection, Cesarean Section; Infection
Interventions
Abdominal Closure Bundle
Procedure
Lead sponsor
Abington Memorial Hospital
Other
Eligibility
18 Years and older · Female only
Enrollment
850 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Abington, Pennsylvania
Conditions
Surgical Site Infection in Obese Women Undergoing C-section
Interventions
cephalexin & metronidazole, placebo
Drug
Lead sponsor
University of Cincinnati
Other
Eligibility
13 Years and older · Female only
Enrollment
475 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2010
U.S. locations
1
States / cities
Cincinnati, Ohio
Conditions
Cesarean Section Complications, Cesarean Wound; Dehiscence, Cesarean Wound Disruption
Interventions
PICO Negative Pressure Wound Therapy, Standard Dressing
Device
Lead sponsor
Northwell Health
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
153 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
New Hyde Park, New York
Conditions
Surgical Site Infection, Cesarean Section; Complications, Wound, Infection (Following Delivery), Postpartum Complication
Interventions
Steri3X, Control
Device · Other
Lead sponsor
University of Tennessee
Other
Eligibility
16 Years and older · Female only
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Memphis, Tennessee
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Antimicrobial Dressing Versus Standard Dressing in Obese Women Undergoing Cesarean Delivery

NCT03887299
Conditions
Cesarean Section Complications, Wound Breakdown, Wound Infection, Satisfaction, Surgical Wound Infection
Interventions
ReliaTect™ Post-Op Dressing (contains chlorohexidine gluconate or CHG), Standard Wound Care
Combination Product · Other
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
154 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Galveston, Texas
Conditions
Cesarean Section Complications, Wound Infection
Interventions
Skin preparation patterns with ChloraPrep 2 x 26 mL single
Procedure
Lead sponsor
Albert Einstein Healthcare Network
Other
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania