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Showing 1–24 of 1,315 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Cessation, Smoking Clear all
Terminated No phase listed Observational Accepts healthy volunteers

Smoking Cessation Program: A Quality Improvement Trial in a Resident-Based Outpatient Clinic

NCT00436943
View directory record Official record
Conditions
Smoking
Interventions
nicotine replacement therapy and bupropion, smoking cessation counseling and referrals
Drug · Behavioral
Lead sponsor
Atlantic Health System
Other
Eligibility
21 Years and older
Enrollment
900 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
Morristown, New Jersey
Source: ClinicalTrials.gov public record
Updated Jul 11, 2010 · Synced Sep 11, 2026, 11:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Testing Different Theories of Smoking Cessation: An Intervention Study

NCT01209897
View directory record Official record
Conditions
Smoking Cessation
Interventions
Smoking cessation booklet
Behavioral
Lead sponsor
University of Hawaii
Other
Eligibility
18 Years and older
Enrollment
1,826 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Honolulu, Hawaii
Source: ClinicalTrials.gov public record
Updated May 13, 2024 · Synced Sep 11, 2026, 11:53 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Vaped Phenanthrene

NCT07134426
View directory record Official record
Conditions
Former Smoker, Non-Smoker
Interventions
D10-phenanthrene
Other
Lead sponsor
University of Minnesota
Other
Eligibility
21 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Sep 11, 2026, 11:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

YMCA Exercise Intervention for Smoking Cessation Study

NCT03080090
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Aerobic exercise, Smoking Cessation Intervention
Behavioral
Lead sponsor
Jasper A. Smits
Other
Eligibility
18 Years to 65 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jun 14, 2026 · Synced Sep 11, 2026, 11:53 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Exenatide Once Weekly for Smoking Cessation

NCT02975297
View directory record Official record
Conditions
Smoking Cessation
Interventions
Exenatide, NRT, Counseling, Placebo
Drug · Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 75 Years
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 27, 2021 · Synced Sep 11, 2026, 11:53 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Novel Psychosocial Influences on Smoking Cessation

NCT02173938
View directory record Official record
Conditions
Smoking
Interventions
Tobacco Dependence Treatment
Other
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years and older · Female only
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated May 3, 2015 · Synced Sep 11, 2026, 11:53 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Zonisamide Augmentation of Varenicline Treatment for Smoking Cessation

NCT01685996
View directory record Official record
Conditions
Nicotine Dependence
Interventions
zonisamide, placebo
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 65 Years
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 23, 2018 · Synced Sep 11, 2026, 11:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mobile Cessation Support for Latino Smokers

NCT03586596
View directory record Official record
Conditions
Smoking Cessation
Interventions
The Decídetext program, Standard Care Control
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
21 Years and older
Enrollment
457 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
3
States / cities
Kansas City, Kansas • Hackensack, New Jersey • Rochester, New York
Source: ClinicalTrials.gov public record
Updated Apr 11, 2024 · Synced Sep 11, 2026, 11:53 PM EDT
Completed Not applicable Interventional Results available

Smoking Cessation Using Motivational Therapy and Varenicline

NCT00701896
View directory record Official record
Conditions
Smoking, HIV Infections
Interventions
Varenicline tartrate, Nicotine Replacement Therapy, Biological Control, Motivational Interview
Drug · Other · Behavioral
Lead sponsor
Philip Diaz
Other
Eligibility
18 Years and older
Enrollment
294 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 14, 2021 · Synced Sep 11, 2026, 11:53 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Bupropion Treatment for Youth Smoking Cessation

NCT00344695
View directory record Official record
Conditions
Nicotine Dependence
Interventions
bupropion SR
Drug
Lead sponsor
University of Arizona
Other
Eligibility
14 Years to 17 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
Ends 2003
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Jun 26, 2006 · Synced Sep 11, 2026, 11:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Smoke-free Home Intervention in Permanent Supportive Housing

NCT04855357
View directory record Official record
Conditions
Smoking Cessation, Second Hand Tobacco Smoke
Interventions
Resident counselling, Staff Training
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
452 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Sep 11, 2026, 11:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Pilot Randomized Controlled Trial of a Smart Phone-Based Smoking Cessation Program

NCT04955639
View directory record Official record
Conditions
Smoking Cessation
Interventions
Control, Pivot
Other
Lead sponsor
Jennifer Marler, MD
Industry
Eligibility
21 Years and older
Enrollment
188 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
San Carlos, California
Source: ClinicalTrials.gov public record
Updated Jun 30, 2024 · Synced Sep 11, 2026, 11:53 PM EDT
Recruiting Phase 4 Interventional

Modifying Progesterone and Estradiol Levels to Prevent Postpartum Cigarette Smoking Relapse and Reduce Secondhand Smoke Exposure in Infants and Children

NCT04783857
View directory record Official record
Conditions
Smoking, Smoking Cessation, Smoking Reduction
Interventions
Progesterone 200 MG Oral Capsule
Drug
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
171 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 12, 2026 · Synced Sep 11, 2026, 11:53 PM EDT
Completed Not applicable Interventional

Using Machine Learning to Develop Just-in-Time Adaptive Interventions for Smoking Cessation

NCT04839198
View directory record Official record
Conditions
Smoking Cessation
Interventions
Android Wear smartwatch, Adaptive Treatment, Nicotine Patch, interviewing-based counseling
Behavioral · Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 27, 2025 · Synced Sep 11, 2026, 11:53 PM EDT
Completed Phase 1 Interventional

Combinations of Pharmacologic Smoking Cessation Treatments

NCT00018187
View directory record Official record
Conditions
Smoking
Interventions
Bupropion, Mecamylamine, Nicotine Patch
Drug
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
20 Years to 40 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
1998 – 2001
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 20, 2009 · Synced Sep 11, 2026, 11:53 PM EDT
Recruiting Not applicable Interventional

Impact of Behavior Modification Interventions and Lung Cancer Screening on Smoking Cessation in People Living With HIV: A Feasibility Study

NCT04949464
View directory record Official record
Conditions
HIV Infection, Tobacco-Related Carcinoma
Interventions
Computed Tomography, Smoking Cessation Intervention
Procedure · Behavioral
Lead sponsor
AIDS Malignancy Consortium
Network
Eligibility
45 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
11
States / cities
La Jolla, California • Washington D.C., District of Columbia • Tampa, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Sep 11, 2026, 11:53 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Assessment of a Teachable Moment for Smoking Cessation

NCT00596440
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Transdermal nicotine patch
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
234 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2012
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 27, 2015 · Synced Sep 11, 2026, 11:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Latinos Kick Buts: Mobile Engagement and Cessation Support for Latino Smokers

NCT05278481
View directory record Official record
Conditions
Smoking Cessation
Interventions
Reward Message with standard introduction, Reward Message with culturally tailored introduction, Threat/Self-efficacy with standard introduction, Threat/Self-efficacy with culturally tailored introduction, Social norms message with standard introduction, Social norms message with culturally tailored introduction
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
21 Years and older
Enrollment
408 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jun 9, 2022 · Synced Sep 11, 2026, 11:53 PM EDT
Completed Phase 2 Interventional Results available

Enhancing Self Regulation Among Smokers

NCT04161144
View directory record Official record
Conditions
Smoking Cessation, Smoking, Cigarette, Nicotine Dependence
Interventions
sirolimus, Placebo
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Mar 8, 2021 · Synced Sep 11, 2026, 11:53 PM EDT
Completed Phase 1 Interventional Results available

Mindfulness-Based Ecological Momentary Intervention For Smoking Cessation Among Cancer Survivors

NCT06476548
View directory record Official record
Conditions
Any Cancer Type
Interventions
EMI
Device
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Apr 1, 2026 · Synced Sep 11, 2026, 11:53 PM EDT
Recruiting Not applicable Interventional

Bladder Cancer Screening Trial

NCT05646485
View directory record Official record
Conditions
Bladder Cancer, Urothelial Carcinoma, Hematuria, Smoking Cessation
Interventions
Urinalysis
Diagnostic Test
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
50 Years and older
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Sep 11, 2026, 11:53 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Project Q Pilot: Smoking Cessation for Light Smokers

NCT03416621
View directory record Official record
Conditions
Tobacco Use Cessation
Interventions
Cognitive behavioral cessation counseling, Counseling and placebo drug intervention, Counseling and active drug intervention
Behavioral · Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years to 65 Years
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 28, 2021 · Synced Sep 11, 2026, 11:53 PM EDT
Recruiting Not applicable Interventional

Wellness Intervention for Smoking and HIV

NCT04725617
View directory record Official record
Conditions
HIV, Sleep, Smoking Cessation, Cardiovascular Diseases
Interventions
Varenicline, Smoking Cessation Counseling, Health Approach 1 to Reduce Smoking, Health Approach 2 to Reduce Smoking
Drug · Behavioral · Other
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 75 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
2
States / cities
Phoenix, Arizona • Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 18, 2025 · Synced Sep 11, 2026, 11:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Shared Decision Making in Rural Primary Care Lung Cancer Screening and Smoking Cessation

NCT04897568
View directory record Official record
Conditions
Lung Cancer, Smoking Cessation
Interventions
Patient decision aid
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
50 Years to 80 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 14, 2024 · Synced Sep 11, 2026, 11:53 PM EDT