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Showing 1–24 of 798 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Cessation, Tobacco Clear all
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

FRESH Delivers: An Innovative Approach to Reducing Tobacco Use Among Rural Smokers

NCT05429892
View directory record Official record
Conditions
Tobacco Cessation, Tobacco Dependence, Food Security
Interventions
Smoking cessation counseling and food delivery, Smoking cessation counseling, Food delivery
Behavioral
Lead sponsor
University of Arkansas
Other
Eligibility
21 Years to 75 Years
Enrollment
540 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Jul 24, 2026, 8:06 AM EDT
Completed Phase 3 Interventional

Smoking Cessation in Substance Abuse Treatment Patients: A Feasibility Study

NCT00408265
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Contingency Management
Behavioral
Lead sponsor
UConn Health
Other
Eligibility
18 Years and older · Male only
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 20, 2011 · Synced Jul 24, 2026, 8:06 AM EDT
Completed Not applicable Interventional

Text Messaging to Engage and Retain Veterans in Smoking Cessation Counseling

NCT03177265
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Text messaging prior to first counseling call, Text-to-Enhance, Mail Notice, Telephone Counseling
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
432 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
2
States / cities
San Diego, California • New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 8, 2021 · Synced Jul 24, 2026, 8:06 AM EDT
Not listed Phase 3 Interventional

Implementing Tobacco Control in Dental Practice

NCT00297700
View directory record Official record
Conditions
Smoking
Interventions
Active referral
Behavioral
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
18 Years and older
Enrollment
2,800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jan 10, 2017 · Synced Jul 24, 2026, 8:06 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Effect of Resistance Training on Tobacco-Related Cardiovascular Disease Risk

NCT01705951
View directory record Official record
Conditions
Smoking, Cardiovascular Disease Risk
Interventions
Resistance Training (RT), Nicotine Replacement Therapy (NRT)
Other · Biological
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 35 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 11, 2012 · Synced Jul 24, 2026, 8:06 AM EDT
Completed Not applicable Interventional Results available

Comparing Smoking Cessation Interventions Among Underserved Patients Referred for Lung Cancer Screening

NCT04798664
View directory record Official record
Conditions
Smoking Cessation
Interventions
Removal of Financial Barriers, Financial Incentives, Mobile Health Application
Behavioral
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
18 Years and older
Enrollment
3,228 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
5
States / cities
Oakland, California • Detroit, Michigan • Danville, Pennsylvania + 2 more
Source: ClinicalTrials.gov public record
Updated Feb 24, 2026 · Synced Jul 24, 2026, 8:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Intervention Study to Increase Smoking Cessation Rates Among Public Housing Residents

NCT01651611
View directory record Official record
Conditions
Tobacco Cessation
Interventions
Motivational interviewing, Smoking cessation counseling, Navigation to smoking cessation resources, Social support
Behavioral
Lead sponsor
Boston University
Other
Eligibility
18 Years to 79 Years
Enrollment
330 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 28, 2016 · Synced Jul 24, 2026, 8:06 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Use of a Smartphone Mobile Application (App) to Enhance Smoking Cessation Treatment

NCT03519451
View directory record Official record
Conditions
Depression, Tobacco Use Disorder, Current Every Day Smoker
Interventions
Internet-Based Intervention, Questionnaire Administration
Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years to 65 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Jul 24, 2026, 8:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pilot Trial of Using SmokeBeat to Monitor and Increase Smoking Abstinence in Pregnant Women

NCT03209557
View directory record Official record
Conditions
Tobacco Use Cessation, Pregnancy Related
Interventions
SmartWatch SmokeBeat Application
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
Female only
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Lancaster, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 8, 2019 · Synced Jul 24, 2026, 8:06 AM EDT
Completed Not applicable Interventional Results available

'Questions About Quitting' Smoking Cessation Trial

NCT00992264
View directory record Official record
Conditions
Smoking
Interventions
Message Tone, Navigation, Proactive Outreach, Testimonials
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Enrollment
1,865 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 12, 2017 · Synced Jul 24, 2026, 8:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

eCEASE to Support Treatment for Parental Tobacco Use

NCT04974736
View directory record Official record
Conditions
Tobacco Smoking, Second Hand Tobacco Smoke, Smoking Cessation
Interventions
iEHR + Navigator
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
Not listed
Enrollment
817 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 14, 2025 · Synced Jul 24, 2026, 8:06 AM EDT
Recruiting Phase 4 Interventional

Extended Intervention for Tobacco Use (EXIT) for People Experiencing Homelessness

NCT07148232
View directory record Official record
Conditions
Tobacco Cessation, Tobacco Abstinence, Tobacco Use, Tobacco Use Cessation, Tobacco Dependence
Interventions
Nicotine Replacement Therapy (NRT), Wellness Coaching
Drug · Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Nov 20, 2025 · Synced Jul 24, 2026, 8:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Improving the Delivery of Smoking Cessation Guidelines in Hospitalized Veterans

NCT00816036
View directory record Official record
Conditions
Cigarette Smoking
Interventions
Smoking Cessation Guideline Implementation
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
898 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
4
States / cities
Denver, Colorado • Iowa City, Iowa • Minneapolis, Minnesota + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 26, 2015 · Synced Jul 24, 2026, 8:06 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Tobacco Cessation for Sexual Minorities

NCT03643679
View directory record Official record
Conditions
Smoking Cessation
Interventions
Kwit smartphone app
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 30 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 6, 2020 · Synced Jul 24, 2026, 8:06 AM EDT
Completed Not applicable Interventional

Effectiveness of an Integrated Treatment to Address Smoking Cessation and Anxiety/ Depression in People Living With HIV

NCT03904186
View directory record Official record
Conditions
Human Immunodeficiency Virus, Smoking Cessation, Smoking, Cigarette, Smoking, Anxiety, Depression, Nicotine Dependence
Interventions
QUIT, Time-Matched Control (TM)
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 79 Years
Enrollment
131 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
3
States / cities
Boston, Massachusetts • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 8, 2026 · Synced Jul 24, 2026, 8:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Study of Mobile Phone Support for the DC Tobacco Quitline

NCT01817842
View directory record Official record
Conditions
Smoking Cessation
Interventions
Mobile EX cessation support, DC Quitline Support, Device Control
Behavioral
Lead sponsor
Truth Initiative
Other
Eligibility
18 Years and older
Enrollment
803 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Mar 25, 2013 · Synced Jul 24, 2026, 8:06 AM EDT
Completed Phase 3 Interventional Results available

Smoking-Cessation and Stimulant Treatment (S-CAST)

NCT01077024
View directory record Official record
Conditions
Cocaine Dependence, Methamphetamine Dependence, Nicotine Dependence
Interventions
Smoking-cessation treatment
Other
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years and older
Enrollment
538 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
12
States / cities
Tucson, Arizona • Rancho Cucamonga, California • Tarzana, California + 9 more
Source: ClinicalTrials.gov public record
Updated Sep 28, 2021 · Synced Jul 24, 2026, 8:06 AM EDT
Completed Phase 3 Interventional Results available

Smoking Cessation With the Nicotine Patch: A Pilot Study of Patch Messaging

NCT01287377
View directory record Official record
Conditions
Smoking Cessation
Interventions
Telephone Counseling, Nicotine Patches
Behavioral · Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
243 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Feb 12, 2020 · Synced Jul 24, 2026, 8:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Pivot Breath Sensor Performance Study

NCT03870022
View directory record Official record
Conditions
Smoking Cessation, Smoking, Tobacco
Interventions
Pivot Breath Sensor System, Similar Carbon Monoxide breath sensor system
Device
Lead sponsor
Jennifer Marler, MD
Industry
Eligibility
18 Years to 80 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Redwood City, California
Source: ClinicalTrials.gov public record
Updated Jun 30, 2024 · Synced Jul 24, 2026, 8:06 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Adverse Airway Effects From Tobacco and E-Cigarettes

NCT03251053
View directory record Official record
Conditions
Airway Morbidity, Smoking Cessation, Nicotine Adverse Reaction, Smoking, Tobacco, Smoking, Cigarette
Interventions
Electronic cigarette use, Control regular cigarette smokers
Device · Other
Lead sponsor
Miami VA Healthcare System
Federal
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Aug 15, 2017 · Synced Jul 24, 2026, 8:06 AM EDT
Withdrawn Not applicable Interventional

Progesterone and Atomoxetine for Cocaine Cessation

NCT01741376
View directory record Official record
Conditions
Cocaine Dependence, Nicotine Dependence
Interventions
Progesterone, Placebo
Drug
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 60 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 5, 2019 · Synced Jul 24, 2026, 8:06 AM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

Semaglutide for Post-Smoking Cessation Weight Management

NCT06173778
View directory record Official record
Conditions
Obesity, Overweight, Cigarette Smoking
Interventions
semaglutide 2.4mg, Placebo, Nicotine Replacement Therapy (NRT, nicotine patch), Brief Smoking Cessation Counseling
Drug · Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 75 Years
Enrollment
197 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
2
States / cities
Austin, Texas • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 10, 2026 · Synced Jul 24, 2026, 8:06 AM EDT
Completed Not applicable Interventional

Evidence-Based Tobacco Cessation Strategies in Patients With Cancer

NCT02211196
View directory record Official record
Conditions
Malignant Neoplasm
Interventions
smoking cessation intervention, survey administration, questionnaire administration
Behavioral · Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
Not listed
Enrollment
377 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 2, 2018 · Synced Jul 24, 2026, 8:06 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

CO Monitoring for Tobacco Cessation in Quitlines

NCT05327660
View directory record Official record
Conditions
Tobacco Dependence
Interventions
Quitline Treatment as Usual (TAU), Remote Carbon Monoxide (CO) Monitoring, Incentivized Remote CO Monitoring
Combination Product
Lead sponsor
Consumer Wellness Solutions
Industry
Eligibility
18 Years and older
Enrollment
229 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 27, 2024 · Synced Jul 24, 2026, 8:06 AM EDT