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ClinicalTrials.gov public records Last synced Nov 15, 2026, 5:39 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 810 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Cessation, Tobacco Clear all

Conditions: Nicotine Dependence
Interventions: Placebo, Varenicline; Drug
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years to 65 Years
Enrollment: 62 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2007
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Nicotine Dependence, Opiate Dependence
Interventions: Intensive, tailored intervention, NJ Quitline Referral; Behavioral
Lead sponsor: Rutgers, The State University of New Jersey; Other
Eligibility: 18 Years and older
Enrollment: 87 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: New Brunswick, New Jersey

Conditions: Smoking
Interventions: Web+Mobile, Web Only; Behavioral
Lead sponsor: Oregon Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 1,266 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 1
States / cities: Eugene, Oregon

Conditions: Tobacco Cessation
Interventions: Tailored behavioral counseling, Tobacco cessation pharmacotherapy; Behavioral · Drug
Lead sponsor: Iowa City Veterans Affairs Medical Center; Federal
Eligibility: 18 Years to 99 Years
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Bladder Cancer
Interventions: questionnaires, Saliva and/or urine sample; Behavioral · Other
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 600 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2027
U.S. locations: 4
States / cities: Basking Ridge, New Jersey • Commack, New York • Harrison, New York + 1 more

Conditions: Smoking
Interventions: Smokers cease smoking; Behavioral
Lead sponsor: University of Vermont; Other
Eligibility: 18 Years and older
Enrollment: 287 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2015
U.S. locations: 2
States / cities: Hanover, New Hampshire • Burlington, Vermont

Conditions: Nicotine Dependence
Interventions: Standard Treatment, Traditional Contingency Management, Early Enhanced Contingency Management; Behavioral
Lead sponsor: Wayne State University; Other
Eligibility: 13 Years and older
Enrollment: 84 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2011
U.S. locations: 1
States / cities: Detroit, Michigan

Conditions: Tobacco Dependence
Interventions: C-Raven Virtual Tobacco Cessation Counseling, Nicotine Replacement Product, Community Health Worker, Lung Cancer Screening; Behavioral · Drug · Other
Lead sponsor: Johns Hopkins University; Other
Eligibility: 50 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Tobacco Use, Tobacco Use Cessation
Interventions: Tobacco counseling resources; Behavioral
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years and older
Enrollment: 4,800 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Smokeless Tobacco Cessation
Interventions: #EnufSnuff.TXT- First Responder, Enough Snuff Intervention; Behavioral
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Tobacco Use Disorder
Interventions: Internet-delivered continuing professional development, No intervention arm; Behavioral · Other
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 19 Years and older
Enrollment: 190 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2003 – 2008
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Tobacco Use, Smoking, Smoking Cessation
Interventions: Cognitive-Motivational Feedback, Staff Tobacco Quit Line Referral Implementation Support, Consumer Incentives for Immediate Referral to a Tobacco Quit Line; Behavioral
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years and older
Enrollment: 96 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Cigarette Smoking, Nicotine Dependence
Interventions: Counseling Intervention, Information Intervention; Behavioral
Lead sponsor: University of Massachusetts, Worcester; Other
Eligibility: 13 Years to 18 Years
Enrollment: 1,058 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2010
U.S. locations: 1
States / cities: Worcester, Massachusetts

Conditions: Nicotine Dependence, Smoking
Interventions: N-acetylcysteine (NAC), Placebo; Drug · Other
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years to 65 Years
Enrollment: 114 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2019
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Tobacco Use Disorder, Smoking Cessation
Interventions: Web-based curriculum on tobacco dependence treatment, Tobacco Counseling Role Play, Preceptor Training and Teaching Medical Students, Booster Session; Behavioral
Lead sponsor: University of Massachusetts, Worcester; Other
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2014
U.S. locations: 13
States / cities: Birmingham, Alabama • Stanford, California • Washington D.C., District of Columbia + 10 more

Conditions: Smoking, Cigarette, Breastfeeding
Interventions: Integrated intervention of smoking cessation and breastfeeding, Attention placebo control; Behavioral
Lead sponsor: Xiaozhong Wen; Other
Eligibility: 18 Years and older · Female only
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Buffalo, New York

Conditions: Smoking Cessation
Interventions: Non-invasive vagus nerve stimulator plus nicotine replacement patches, nicotine replacement patches; Combination Product · Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Tobacco Use Cessation, Post Traumatic Stress Disorders
Interventions: Motivation Interviewing Counseling; Behavioral
Lead sponsor: US Department of Veterans Affairs; Federal
Eligibility: 18 Years and older
Enrollment: 178 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2014
U.S. locations: 1
States / cities: Denver, Colorado

Conditions: Cigarette Smoking, Tobacco Smoking, Smoking, Tobacco
Interventions: nicotine patch plus nicotine gum/lozenge, Intensive Alcohol Intervention; Drug · Behavioral
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years to 75 Years
Enrollment: 352 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2018
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Adherence, Tobacco Use Cessation, Alcohol & Drug Use, Nicotine Transdermal System
Interventions: Lifestyle counseling; Behavioral
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 25 Years
Enrollment: 41 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2008
U.S. locations: 3
States / cities: Jacksonville, Florida • Rochester, Minnesota

Conditions: Tobacco Use Cessation
Interventions: Path2Quit - culturally specific text message intervention; Behavioral
Lead sponsor: Case Comprehensive Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 35 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Smoking Cessation, Smoking, Nicotine Dependence
Interventions: Varenicline, Nicotine lozenge, Nicotine Patch; Drug
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years to 99 Years
Enrollment: 1,086 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2017
U.S. locations: 2
States / cities: Madison, Wisconsin • Milwaukee, Wisconsin

Conditions: Tobacco Use Disorder
Interventions: AAT-experiment, AAT-placebo; Behavioral
Lead sponsor: Yale University; Other
Eligibility: 13 Years to 18 Years
Enrollment: 66 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Cigarette Smoking
Interventions: C2Q-Teen app, NCI's QuitSTART app, Written smoking cessation materials only; Behavioral
Lead sponsor: University of Massachusetts, Worcester; Other
Eligibility: 13 Years to 19 Years
Enrollment: 146 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Worcester, Massachusetts

Search by objective public record fields.

Effects of Chantix on Relapse Prevention for Smoking Cessation

Developing a Smoking Cessation Intervention for Methadone Maintained Smokers

Web and Mobile Smoking Cessation

A Stepped Care Approach to Treating Tobacco Use in Rural Veterans

Determinants of Bladder Cancer Recurrence Study (The DETER Study)

Effects of Quitting Study A Test of Pre-clinical Findings

Prize Reinforcement for Smoking Cessation

C-Raven, a Virtual Tobacco Cessation Intervention in the Community

Automating Tobacco Cessation in Primary Care

Smokeless Tobacco Cessation Intervention for Firefighters

Dental Tobacco Control.Net:Improving Practice

Salvation Army Tobacco Quit Line Referral Implementation Trial

School Nurse-Delivered Smoking Cessation Intervention

N-acetylcysteine for Tobacco Use Disorder

Tobacco Treatment Medical Education in 10 Medical Schools

Lung and Breast Cancer Prevention by an Integrated Intervention of Maternal Smoking Cessation and Breastfeeding

A Study Of Vagal Nerve Stimulation In Conjunction With NRT For Smoking Cessation

Tobacco Cessation for Veterans With Post Traumatic Stress Disorder (PTSD)

Enhancing Smoking Cessation in the Homeless Population

Smoking Cessation for Young Adults Who Binge Drink - 1

Feasibility of a Culturally-Specific Video Text Cessation Intervention With AA Quitline Callers

A Comparative Effectiveness & Long Term Health Study in Wisconsin Smokers

Tobacco Approach Avoidance Training for Adolescent Smokers-2

Developing a Smartphone App With Mindfulness Training for Teen Smoking Cessation