Independent directory Public ClinicalTrials.gov records United States
Clear filters

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Oct 14, 2026, 1:25 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 361–384 of 807 matching trials from the live ClinicalTrials.gov search.
Completed Not applicable Interventional Results available

Development and Pilot Testing of the Sense2Quit App

NCT05609032
Conditions
Smoking Cessation, HIV Infections
Interventions
Sense2Quit App
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
New York, New York
Conditions
Tobacco, Posttraumatic Stress Disorder
Interventions
Acceptance and Commitment Therapy for PTSD and Tobacco Use, Freedom From Smoking
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Bedford, Massachusetts
Conditions
Smoking, Smoking Cessation, Tobacco Use Cessation
Interventions
Usual Care, RiskProfile-Clin, RiskProfile-Gen
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
915 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
St Louis, Missouri
Completed Not applicable Interventional Accepts healthy volunteers

Real Time fMRI and Quitting Smoking

NCT03302026
Conditions
Nicotine Use Disorder
Interventions
Realtime biofeedback using fMRI
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 65 Years
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Tobacco Dependence
Interventions
C-Raven Virtual Tobacco Cessation Counseling, Nicotine Replacement Product, Community Health Worker, Lung Cancer Screening
Behavioral · Drug · Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
50 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Tobacco Use, Tobacco Smoking, Cigarette Smoking, Smokeless Tobacco Cessation
Interventions
Electronic Cigarette, Oral Nicotine Pouch
Other
Lead sponsor
Roswell Park Cancer Institute
Other
Eligibility
21 Years to 55 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Buffalo, New York
Conditions
Tobacco Cessation, HIV, AIDS
Interventions
Treatment as usual, AIR (Aspirations, Inspiration, Respiration)
Behavioral
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2019
U.S. locations
1
States / cities
New York, New York
Conditions
Cannabis Dependence
Interventions
MET/CBT/CM plus NRT
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
2
States / cities
Concord, New Hampshire • Lebanon, New Hampshire
Completed Not applicable Interventional Accepts healthy volunteers

Prolonged Smoking Cessation Using Prescription Step Care

NCT00170079
Conditions
Tobacco Dependence
Interventions
Smoking Cessation Intervention
Behavioral
Lead sponsor
University of Tennessee
Other
Eligibility
18 Years and older
Enrollment
270 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2011
U.S. locations
2
States / cities
Rochester, Minnesota • Memphis, Tennessee
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Incentives for Oklahoma Tobacco Helpline Engagement in Persistent Poverty Counties

NCT05095779
Conditions
Cigarette Smoking, Nicotine Dependence
Interventions
Coaching calls, Nicotine replacement therapy, Financial Incentives
Behavioral · Drug
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years and older
Enrollment
165 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Completed Not applicable Interventional Accepts healthy volunteers Results available

Empowering LGBTQ+ Tobacco Cessation Pilot

NCT05365633
Conditions
Smoking Cessation
Interventions
Empowerment activity-enhanced tobacco cessation assistance
Behavioral
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Completed Phase 4 Interventional Results available

Tobacco Treatment Comparison for Cancer Care

NCT06218823
Conditions
Smoking Cessation, Cancer
Interventions
Transdermal Nicotine Patch, Standard Telephone Counseling, Varenicline, Cancer-Targeted Telephone Counseling, Mailed Information about Standard Care Resources
Drug · Behavioral · Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Madison, Wisconsin
Conditions
Smoking Cessation, Tobacco Use Cessation
Interventions
SSR591813L (dianicline)
Drug
Lead sponsor
Sanofi
Industry
Eligibility
18 Years and older
Enrollment
630 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Bridgewater, New Jersey
Completed Not applicable Interventional Accepts healthy volunteers

Functional Assessment Screening Patient Reported Information

NCT01669564
Conditions
Quality of Life, Tobacco Use Cessation, Physical Activity
Interventions
Will use HIT patient feedback to activate patients., Patients will not receive HIT patient feedback.
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
666 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Thromboangiitis Obliterans (Buerger's Disease)
Interventions
ATI-1013 (0.2 g), ATI-1013 (0.8 g), ATI-1013 (3.2 g), Placebo
Biological · Other
Lead sponsor
Antidote Therapeutics, Inc
Industry
Eligibility
23 Years to 59 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Overland Park, Kansas
Completed Phase 1 Interventional Accepts healthy volunteers

Tobacco Cessation Treatment for Alaska Native Youth

NCT01099384
Conditions
Tobacco Cessation
Interventions
Written self-help materials, Group behavioral counseling
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
12 Years to 17 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Bethel, Alaska
Active, not recruiting Phase 4 Interventional Accepts healthy volunteers

Implementing Tobacco Treatment in Low Dose CT Lung Cancer Screening Sites

NCT03315910
Conditions
Smoking Cessation
Interventions
Motivational Interviewing (MI), Nicotine Replacement Therapy (NRT), Nicotine Lozenge, Message Framing, saliva sample
Behavioral · Drug · Other
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
50 Years to 80 Years
Enrollment
807 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2026
U.S. locations
18
States / cities
Los Angeles, California • Walnut Creek, California • La Grange, Georgia + 14 more
Conditions
Nicotine Dependence, Tobacco Use
Interventions
Nicotine replacement therapy - Transdermal nicotine patch, Nicotine replacement therapy - Nicotine gum, Nicotine replacement therapy - Nicotine lozenge, Bupropion, Varenicline, Combination pharmacotherapy - Transdermal nicotine patch + nicotine gum, Combination pharmacotherapy - Transdermal nicotine patch + nicotine lozenge, Combination pharmacotherapy - Transdermal nicotine patch + bupropion, Tobacco quitline referral, Tailored behavioral intervention, Alcohol use risk reduction, Behavioral activation for depressive symptoms, Behavioral management of postcessation weight gain
Drug · Behavioral
Lead sponsor
Mark Vander Weg
Other
Eligibility
18 Years to 99 Years
Enrollment
411 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
1
States / cities
Iowa City, Iowa
Conditions
Nicotine Dependence, Psychotic Disorders
Interventions
Contingency Management, Reward
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
Seattle, Washington
Completed Not applicable Interventional Results available

Goal2Quit + NRT Sampling

NCT03837379
Conditions
Cigarette Smoking, Smoking Cessation, Depression
Interventions
Treatment as Usual, Goal2Quit + NRT Sampling
Behavioral · Combination Product
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
164 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Charleston, South Carolina
Conditions
Cancer and Tobacco Abuse
Interventions
Bupropion and intensive behavioral therapy
Drug
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
Indianapolis, Indiana
Conditions
Smoking Cessation, Nicotine Dependence
Interventions
NicVAX vaccine, Placebo
Biological
Lead sponsor
Nabi Biopharmaceuticals
Industry
Eligibility
18 Years to 65 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
12
States / cities
Newport Beach, California • San Diego, California • Miami, Florida + 9 more
Not listed Not applicable Interventional Accepts healthy volunteers

Testing a Self-affirmation Intervention for Use in a Mobile Application

NCT03405220
Conditions
Smoking, Smoking Cessation, Smoking, Tobacco
Interventions
Self affirmation, 10 items, written examples, Self affirmation, 10 items, no examples, Self affirmation, 10 items, imagined examples, Self affirmation, 5 items, written examples, Self affirmation, 5 items, no examples, Self affirmation, 5 items, imagined examples, Self affirmation, 3 items, written examples, Self affirmation, 3 items, no examples, Self affirmation, 3 items, imagined examples
Behavioral
Lead sponsor
Kent State University
Other
Eligibility
21 Years to 65 Years
Enrollment
900 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Kent, Ohio
Recruiting Not applicable Interventional Accepts healthy volunteers

Take A Break - Rural

NCT05790486
Conditions
Smoking, Smoking Behaviors, Smoking Cessation
Interventions
Take a Break plus Nicotine replacement therapy (NRT) Sampling, The Comparison, Community Paramedicine Standard Plus Enhanced Implementation Program, Community Paramedicine Standard Implementation Program
Behavioral · Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
800 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Winston-Salem, North Carolina