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ClinicalTrials.gov public records Last synced Oct 15, 2026, 1:41 AM EDT

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Showing 577–600 of 807 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Cessation, Tobacco Clear all
Terminated Not applicable Interventional

Evaluation of a Computer-Delivered 5 A's Intervention for Smoking

NCT01383278
View directory record Official record
Conditions
Smoking
Interventions
Computer-directed 5 A's intervention for smoking, Screening and resource provision
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years to 65 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Dec 21, 2015 · Synced Oct 15, 2026, 1:41 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Testing Counseling Styles to Motivate Smokers to Quit

NCT01188018
View directory record Official record
Conditions
Smoking, Tobacco Use, Nicotine Dependence
Interventions
Brief Advice (BA), Motivational Interviewing (MI), Health Education (HE)
Behavioral
Lead sponsor
University of Missouri, Kansas City
Other
Eligibility
18 Years and older
Enrollment
255 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 4, 2012 · Synced Oct 15, 2026, 1:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Electronic Cigarette Use on the Lungs

NCT02596685
View directory record Official record
Conditions
Current Smoker, Never Smoker, Tobacco Use Disorder, Former Smoker, E-cig User
Interventions
Bronchoscopy, Electronic Cigarette, Laboratory Biomarker Analysis, Questionnaire Administration
Procedure · Other
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
21 Years to 45 Years
Enrollment
142 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2021
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 30, 2024 · Synced Oct 15, 2026, 1:41 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Sustaining Smoking Cessation in Smokers With Kids With Asthma

NCT00862368
View directory record Official record
Conditions
Asthma, Smoking Cessation
Interventions
PAM, PAM-Enhanced/Asthma Counseling Phone Calls, Follow-Up Phone Calls - Child Wellness Topic
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years and older
Enrollment
573 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2011
U.S. locations
5
States / cities
Fall River, Massachusetts • Pawtucket, Rhode Island • Providence, Rhode Island + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 25, 2012 · Synced Oct 15, 2026, 1:41 AM EDT
Completed Not applicable Interventional Results available

Varenicline or Nicotine Patch in Promoting Smoking Cessation Among Current Smokers

NCT01771627
View directory record Official record
Conditions
Tobacco Use Disorder
Interventions
varenicline, nicotine patch
Drug
Lead sponsor
Roswell Park Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Sep 28, 2020 · Synced Oct 15, 2026, 1:41 AM EDT
Completed Phase 3 Interventional

Telephone and Web-based Teen Tobacco Cessation in HMOs

NCT00311948
View directory record Official record
Conditions
Tobacco Use
Interventions
Telephone counseling + interactive website = more abstinence, Behavioral: interactive website
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
15 Years to 18 Years
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
3
States / cities
Eugene, Oregon • Portland, Oregon • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Sep 28, 2012 · Synced Oct 15, 2026, 1:41 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Catalyzing Cigarette Smoking Cessation Through Harm Reduction Sampling Among People Unmotivated to Quit

NCT07199517
View directory record Official record
Conditions
Cigarette Smoking, Tobacco Use, Cigarette Smoking Behavior
Interventions
HRP Sampling period, NPL Sampling period
Other
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
21 Years and older
Enrollment
472 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Oct 15, 2026, 1:41 AM EDT
Completed Not applicable Interventional Results available

Novel Medication as a Potential Smoking Cessation Aid

NCT02265367
View directory record Official record
Conditions
Tobacco Use Disorder
Interventions
Levomilnacipran, Placebo
Drug
Lead sponsor
University of Minnesota
Other
Eligibility
25 Years to 55 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 22, 2022 · Synced Oct 15, 2026, 1:41 AM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

Dyadic Financial Incentive Treatments for Dual Smoker Couples

NCT06296849
View directory record Official record
Conditions
Smoking, Cigarette
Interventions
Financial Incentive Treatment (FIT)
Behavioral
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years and older
Enrollment
900 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
2
States / cities
Athens, Georgia • Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Oct 15, 2026, 1:41 AM EDT
Not listed Not applicable Interventional

The Positively Quit Trial for Smoking Cessation

NCT04449458
View directory record Official record
Conditions
Cigarette Smoking
Interventions
Positively Me, Positively Living
Behavioral
Lead sponsor
University of South Florida
Other
Eligibility
18 Years and older
Enrollment
482 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Jul 23, 2024 · Synced Oct 15, 2026, 1:41 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Feasibility of Delivering VergeRx at FQHCs

NCT06161675
View directory record Official record
Conditions
Tobacco Use Cessation
Interventions
QuitAid, SmokefreeTXT, Nicotine Replacement Therapy Patch, Nicotine lozenge
Behavioral · Drug
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 30, 2025 · Synced Oct 15, 2026, 1:41 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Advancing Tobacco Use Treatment for African American Smokers

NCT02360631
View directory record Official record
Conditions
Smoking Cessation
Interventions
Chantix, Placebo
Drug
Lead sponsor
Lisa Sanderson Cox, PhD
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
2
States / cities
Kansas City, Kansas • Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 15, 2020 · Synced Oct 15, 2026, 1:41 AM EDT
Completed Phase 4 Interventional Results available

Cannabis and Tobacco Co-use Study

NCT04228965
View directory record Official record
Conditions
Tobacco Use Disorder
Interventions
Varenicline, Contingency Management, Counseling
Drug · Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 40 Years
Enrollment
181 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
3
States / cities
Charleston, South Carolina • Florence, South Carolina • Pickens, South Carolina
Source: ClinicalTrials.gov public record
Updated Jun 15, 2025 · Synced Oct 15, 2026, 1:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Coping Skills Treatment for Smoking Cessation

NCT01061528
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Transdermal Nicotine
Drug
Lead sponsor
Butler Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
116 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Oct 16, 2018 · Synced Oct 15, 2026, 1:41 AM EDT
Completed Not applicable Interventional Results available

Innovative Digital Therapeutic for Smoking Cessation

NCT03694327
View directory record Official record
Conditions
Smoking Cessation, Nicotine Addiction, Drug Addiction, Drug Dependence, Tobacco Dependence, Tobacco Use Disorder, Substance Use Disorder, Tobacco Smoking
Interventions
CT-101-M, QuitGuide
Device
Lead sponsor
My Digital Study
Industry
Eligibility
18 Years to 65 Years
Enrollment
158 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 6, 2022 · Synced Oct 15, 2026, 1:41 AM EDT
Not listed Not applicable Interventional

Smoking Cessation Following Psychiatric Hospitalization

NCT02204956
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Sustained Care, Usual Care
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years and older
Enrollment
422 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated May 11, 2018 · Synced Oct 15, 2026, 1:41 AM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

E-cigarette Cessation in Adults Who Co-use Cannabis

NCT06688539
View directory record Official record
Conditions
Nicotine Dependence, Tobacco Use Disorder
Interventions
Varenicline Pill, Contingency management, Counseling
Drug · Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 40 Years
Enrollment
105 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
3
States / cities
Charleston, South Carolina • Lancaster, South Carolina • Pickens, South Carolina
Source: ClinicalTrials.gov public record
Updated Jun 12, 2026 · Synced Oct 15, 2026, 1:41 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

A Smoking Cessation Treatment for Adult Women

NCT01422239
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Tailored treatment, Standard Treatment
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 64 Years · Female only
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 20, 2020 · Synced Oct 15, 2026, 1:41 AM EDT
Recruiting Phase 3 Interventional Accepts healthy volunteers

Early Withdrawal Exposure and Negative Affect Withdrawal (NAW) Regulation Training for Smoking Cessation

NCT03912194
View directory record Official record
Conditions
Tobacco Dependence
Interventions
cognitive-behavioral withdrawal regulation strategies, relaxation strategies, early withdrawal exposure
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2026
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 11, 2026 · Synced Oct 15, 2026, 1:41 AM EDT
Recruiting Phase 4 Interventional

Varenicline and Accelerated Transcranial Magnetic Stimulation (TMS) for Quitting Nicotine Use (Pilot Study)

NCT07145866
View directory record Official record
Conditions
Nicotine Dependence, Transcranial Magnetic Stimulation, Vaping, Smoking Cessation, Smoking (Tobacco) Addiction
Interventions
Varenicline, Transcranial Magnetic Stimulation, Transcranial Magnetic Stimulation Sham, Nicotine Cessation Counseling, D-cycloserine
Drug · Device · Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 15, 2026 · Synced Oct 15, 2026, 1:41 AM EDT
Completed Not applicable Interventional

Project HEALS (Helping and Empowering pAtients for Living a Life Smoke-free

NCT05362318
View directory record Official record
Conditions
Smoking, Tobacco Use, Lung Cancer
Interventions
Nicotine patch and lozenges, Telephone counseling sessions, Access to a web-based video, Florida Tobacco Quitline
Drug · Behavioral
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Apr 6, 2026 · Synced Oct 15, 2026, 1:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Repetitive Transcranial Magnetic Stimulation (rTMS) for Nicotine Addiction

NCT02401672
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Transcranial magnetic stimulation
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 60 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 21, 2020 · Synced Oct 15, 2026, 1:41 AM EDT
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

Smart Olfaction App to Reduce Relapse

NCT07007195
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Ad Libitum Use followed by Instructed Use of the Inspire Device, Instructed Use followed by Ad Libitum Use of the Inspire Device, Smart-T Smoking Cessation App with the Inspire Device Condition, Smart-T Smoking Cessation App Without the Inspire Device Condition, Nicotine replacement therapy (NRT), Inspire Device
Device · Drug
Lead sponsor
University of Houston
Other
Eligibility
18 Years and older
Enrollment
132 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Oct 15, 2026, 1:41 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Tobacco Cessation Via Public Health Dental Clinics

NCT00683839
View directory record Official record
Conditions
Smoking
Interventions
Brief tobacco counseling
Behavioral
Lead sponsor
Oregon Research Institute
Other
Eligibility
18 Years and older
Enrollment
2,637 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2009
U.S. locations
3
States / cities
Jackson, Mississippi • New York, New York • Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Oct 26, 2011 · Synced Oct 15, 2026, 1:41 AM EDT