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ClinicalTrials.gov public records Last synced Oct 6, 2026, 7:53 AM EDT

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Showing 121–144 of 1,264 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Cessation of Smoking Clear all
Completed Phase 4 Interventional Results available

Behaviorally Enhanced Counseling on Nicotine Dependence (BEACON) Trial.

NCT00991081
View directory record Official record
Conditions
Smoking
Interventions
Counseling, Self-help guide, Pharmacotherapy, Genetic feedback, verbal, Genetic feedback, printed
Behavioral · Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
3
States / cities
Menlo Park, California • Stanford, California • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Sep 19, 2012 · Synced Oct 6, 2026, 7:53 AM EDT
Completed Not applicable Interventional

Internet and Telephone Counseling for Smoking Cessation

NCT00282009
View directory record Official record
Conditions
Unspecified Adult Solid Tumor, Protocol Specific
Interventions
Basic Internet, Enhanced Internet, Enhanced Internet + phone
Behavioral
Lead sponsor
Georgetown University
Other
Eligibility
18 Years to 90 Years
Enrollment
2,205 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2015
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Feb 10, 2016 · Synced Oct 6, 2026, 7:53 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Affect Regulation Training for Pregnant Smokers

NCT01163864
View directory record Official record
Conditions
Smoking Cessation
Interventions
affect regulation training, health and lifestyle
Behavioral
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
77 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2011
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Oct 17, 2022 · Synced Oct 6, 2026, 7:53 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Smoking Cessation CM for Veterans With or at Risk for Cancer

NCT06432985
View directory record Official record
Conditions
Tobacco Use Disorder, Substance Use Disorder
Interventions
Focus Group, Contingency Management (CM), TUD Treatment as Usual (TAU)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2031
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 2, 2026 · Synced Oct 6, 2026, 7:53 AM EDT
Completed Not applicable Interventional

Smokefree.Gov Website in Helping United States Federal Employees Quit Smoking

NCT00245076
View directory record Official record
Conditions
Unspecified Adult Solid Tumor, Protocol Specific
Interventions
smoking cessation intervention, internet-based intervention
Behavioral · Other
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
Rockville, Maryland
Source: ClinicalTrials.gov public record
Updated May 1, 2015 · Synced Oct 6, 2026, 7:53 AM EDT
Completed Not applicable Interventional Results available

Increasing Contingency Management Success in Smoking Cessation

NCT00273793
View directory record Official record
Conditions
Smoking
Interventions
Contingency Management
Behavioral
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years and older
Enrollment
328 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jun 21, 2012 · Synced Oct 6, 2026, 7:53 AM EDT
Completed Not applicable Interventional

Smokers' Quitline for Asian Language Speakers

NCT01248832
View directory record Official record
Conditions
Smoking Cessation
Interventions
Telephone Counseling, Self-Help Materials
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 75 Years
Enrollment
2,277 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Feb 13, 2020 · Synced Oct 6, 2026, 7:53 AM EDT
Completed No phase listed Observational

Effect of Lung Cancer Diagnoses on Family Behaviors

NCT01862770
View directory record Official record
Conditions
Lung Cancer, Blood Relatives of Patient w/Lung Cancer, Cigarette Smokers
Interventions
Not listed
Lead sponsor
National Human Genome Research Institute (NHGRI)
NIH
Eligibility
18 Years to 55 Years
Enrollment
507 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
2
States / cities
Tampa, Florida • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 5, 2018 · Synced Oct 6, 2026, 7:53 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Innovative Smartphone Application of a New Behavioral Method to Quit Smoking: Pilot Trial (Smart Quit)

NCT01812070
View directory record Official record
Conditions
Smoking
Interventions
ACT, CBT
Behavioral
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
196 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Mar 6, 2015 · Synced Oct 6, 2026, 7:53 AM EDT
Completed Not applicable Interventional Results available

Randomized Controlled Trial (RCT) of a Motivational Decision Support System

NCT02086162
View directory record Official record
Conditions
Schizophrenia
Interventions
Web-based motivational decision support system, NCI Education
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years to 70 Years
Enrollment
184 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
3
States / cities
Chicago, Illinois • Worcester, Massachusetts • New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated Nov 29, 2018 · Synced Oct 6, 2026, 7:53 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Diabetes Smoking Cessation Incentives Study

NCT04682067
View directory record Official record
Conditions
Smoking Cessation, Diabetes Type 2
Interventions
Contingency Management, Usual Care smoking cessation
Behavioral
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 75 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated May 26, 2022 · Synced Oct 6, 2026, 7:53 AM EDT
Completed Phase 2Phase 3 Interventional Results available

Smoking Cessation & Opioid Dependence Treatment Integration

NCT02854800
View directory record Official record
Conditions
Smoking Cessation, Opioid Related Disorders
Interventions
varenicline
Drug
Lead sponsor
West Virginia University
Other
Eligibility
18 Years and older
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated Aug 14, 2020 · Synced Oct 6, 2026, 7:53 AM EDT
Active, not recruiting No phase listed Observational

Determinants of Bladder Cancer Recurrence Study (The DETER Study)

NCT02400944
View directory record Official record
Conditions
Bladder Cancer
Interventions
questionnaires, Saliva and/or urine sample
Behavioral · Other
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2027
U.S. locations
4
States / cities
Basking Ridge, New Jersey • Commack, New York • Harrison, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Oct 6, 2026, 7:53 AM EDT
Not listed Not applicable Interventional

Stage Ib Trial of mSMART for Smoking Cessation Medication Adherence

NCT02635919
View directory record Official record
Conditions
Nicotine Dependence
Interventions
mSMART
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 3, 2018 · Synced Oct 6, 2026, 7:53 AM EDT
Completed Phase 2Phase 3 Interventional Results available

Comparing NicoBloc to Nicotine Lozenges

NCT03720899
View directory record Official record
Conditions
Smoking Cessation, Nicotine Dependence
Interventions
NicoBloc, Nicotine Lozenge
Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Apr 8, 2025 · Synced Oct 6, 2026, 7:53 AM EDT
Recruiting Not applicable Interventional

Clinical Research Evaluating Smoking Cessation With E-Cigarettes and Nicotine Therapy

NCT06948058
View directory record Official record
Conditions
Smoking Cessation, Obesity and Obesity-related Medical Conditions
Interventions
Electronic Cigarettes (EC), Nicotine replacement therapy (NRT)
Other
Lead sponsor
Brown University
Other
Eligibility
21 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated May 18, 2026 · Synced Oct 6, 2026, 7:53 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Using Computers to Assist in Parental Smoking Cessation in a Pediatric Setting

NCT01334216
View directory record Official record
Conditions
Cigarette Smoking
Interventions
CHICA Smoking Cessation Module, CHICA Placebo
Other
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
362 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Sep 13, 2017 · Synced Oct 6, 2026, 7:53 AM EDT
Terminated Phase 3 Interventional

S0002 - A Program to Quit Smoking With or Without Bupropion in Treating Patients With Stage I or II Non-Small Cell Lung Cancer Who Have Undergone Surgery

NCT00032084
View directory record Official record
Conditions
Lung Cancer
Interventions
smoking cessation intervention, bupropion hydrochloride, nicotine, psychosocial assessment and care
Behavioral · Drug · Procedure
Lead sponsor
SWOG Cancer Research Network
Network
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2004
U.S. locations
175
States / cities
Anniston, Alabama • Mobile, Alabama • Phoenix, Arizona + 115 more
Source: ClinicalTrials.gov public record
Updated Mar 11, 2013 · Synced Oct 6, 2026, 7:53 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

The Natural History of Gene Expression in the Lung Cells of Non-Smokers, Smokers and Ex-Smokers in Health and Disease

NCT00974064
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease (COPD), Smoking, Smoking Cessation, Chronic Bronchitis, Emphysema
Interventions
Not listed
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older
Enrollment
171 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 27, 2020 · Synced Oct 6, 2026, 7:53 AM EDT
Completed Not applicable Interventional Results available

Implementation of Smoking Cessation Within NCI Community Oncology Research Program (NCORP) Sites

NCT03291587
View directory record Official record
Conditions
Smoking Cessation
Interventions
Personnel Training and Coaching Calls
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
1,094 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
49
States / cities
Newark, Delaware • Augusta, Georgia • Savannah, Georgia + 36 more
Source: ClinicalTrials.gov public record
Updated Jul 25, 2022 · Synced Oct 6, 2026, 7:53 AM EDT
Completed Not applicable Interventional Results available

Monitoring of Exhaled Carbon Monoxide to Promote Pre-operative Smoking Cessation

NCT01014455
View directory record Official record
Conditions
Smoking
Interventions
Informing surgical patients about CO monitoring, a brief intervention recommending preoperative abstinence from smoking
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
169 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 22, 2011 · Synced Oct 6, 2026, 7:53 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Combined Treatment for Tobacco and Alcohol Use in Puerto Rico

NCT00570804
View directory record Official record
Conditions
Smoking
Interventions
Telephone Counseling, Telephone Assessments
Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
370 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2021
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 28, 2021 · Synced Oct 6, 2026, 7:53 AM EDT
Completed Phase 1 Interventional

Multiple Dose, Dose Escalation Study of Varenicline Controlled Release Formulation in Adult Smokers

NCT00527150
View directory record Official record
Conditions
Smoking Cessation
Interventions
Varenicline Tartrate
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 55 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
2
States / cities
East Grand Forks, Minnesota • Fargo, North Dakota
Source: ClinicalTrials.gov public record
Updated Jan 11, 2010 · Synced Oct 6, 2026, 7:53 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Facilitating Smoking Cessation With Reduced Nicotine Cigarettes

NCT02796391
View directory record Official record
Conditions
Smoking Cessation
Interventions
Very Low Nicotine Content (VLNC) Cigarettes, One on One Counseling
Drug · Behavioral
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
18 Years and older
Enrollment
163 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Nov 14, 2022 · Synced Oct 6, 2026, 7:53 AM EDT