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ClinicalTrials.gov public records Last synced Oct 7, 2026, 4:13 AM EDT

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Showing 145–168 of 1,264 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Cessation of Smoking Clear all
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

ChatGPT-Supported Text Messaging Program for Smoking Cessation

NCT07079306
View directory record Official record
Conditions
Smoking Cessation
Interventions
BeFree+Bot, BeFree
Behavioral
Lead sponsor
George Washington University
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated May 22, 2026 · Synced Oct 7, 2026, 4:13 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Culturally Specific Interventions: African American Smokers

NCT01811758
View directory record Official record
Conditions
Smoking, Smoking Cessation
Interventions
Culturally Specific CBT, Standard CBT
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 65 Years
Enrollment
345 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
Coral Gables, Florida
Source: ClinicalTrials.gov public record
Updated Jul 10, 2015 · Synced Oct 7, 2026, 4:13 AM EDT
Completed Phase 4 Interventional Results available

A Text Messaging Program for Smokers in Primary Care

NCT03174158
View directory record Official record
Conditions
Smoking Cessation
Interventions
Mailed nicotine replacement therapy, Text messaging, Brief advice
Drug · Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
153 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 7, 2020 · Synced Oct 7, 2026, 4:13 AM EDT
Terminated Not applicable Interventional

Evaluation of a Computer-Delivered 5 A's Intervention for Smoking

NCT01383278
View directory record Official record
Conditions
Smoking
Interventions
Computer-directed 5 A's intervention for smoking, Screening and resource provision
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years to 65 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Dec 21, 2015 · Synced Oct 7, 2026, 4:13 AM EDT
Completed Not applicable Interventional

Addressing Psychological Risk Factors Underlying Smoking Persistence in COPD Patients: The Fresh Start-II Study

NCT04646174
View directory record Official record
Conditions
Copd, Smoking Cessation, Nicotine Dependence, Tobacco Use, Cigarette Smoking
Interventions
Unified Protocol adapted for smoking cessation, American Lung Association self-management strategies for smoking cessation
Behavioral
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 29, 2023 · Synced Oct 7, 2026, 4:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mobile Mindfulness Training for Smoking Cessation

NCT02037360
View directory record Official record
Conditions
Smoking Cessation
Interventions
Active Comparator App/Training, Experimental App/Training
Behavioral
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years to 65 Years
Enrollment
1,251 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 30, 2018 · Synced Oct 7, 2026, 4:13 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Selegiline for Smoking Cessation - 1

NCT00439413
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Selegiline Transdermal Patch, Placebo, Smoking Cessation Counseling
Drug · Behavioral
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
18 Years to 99 Years
Enrollment
246 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
4
States / cities
College Park, Maryland • New Brunswick, New Jersey • Cincinnati, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 2, 2017 · Synced Oct 7, 2026, 4:13 AM EDT
Recruiting Not applicable Interventional

Actívatexto: Advancing Smoking Cessation and Physical Activity Among Latinos

NCT06926608
View directory record Official record
Conditions
Smoking, Smoking Cessation, Physical Inactivity
Interventions
Actívatexto, Decídetexto
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
408 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Sep 18, 2026 · Synced Oct 7, 2026, 4:13 AM EDT
Not yet recruiting Not applicable Interventional

Smartphone-based Incentives Intervention to Increase Smoking Cessation During Pregnancy

NCT07840118
View directory record Official record
Conditions
Smoking During Pregnancy and Postpartum, Perinatal Cigarette Smoking
Interventions
Best Practices, Financial Incentives
Behavioral
Lead sponsor
University of Vermont
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
137 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Sep 24, 2026 · Synced Oct 7, 2026, 4:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Diabetes Smoking Cessation Incentives Study

NCT04682067
View directory record Official record
Conditions
Smoking Cessation, Diabetes Type 2
Interventions
Contingency Management, Usual Care smoking cessation
Behavioral
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 75 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated May 26, 2022 · Synced Oct 7, 2026, 4:13 AM EDT
Completed Not applicable Interventional Results available

Improving Medication Compliance and Smoking Cessation Treatment Outcomes for African American Smokers

NCT00781599
View directory record Official record
Conditions
Smokers
Interventions
Chantix, Adherence Counseling, Standard Counseling
Drug · Behavioral
Lead sponsor
Nikki Nollen, PhD, MA
Other
Eligibility
18 Years to 75 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Jul 11, 2012 · Synced Oct 7, 2026, 4:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effectiveness of Smoking Cessation Guidelines in the Emergency Department

NCT00756704
View directory record Official record
Conditions
Cigarette Smoking
Interventions
Smoking cessation guideline implementation
Behavioral
Lead sponsor
University of Iowa
Other
Eligibility
18 Years and older
Enrollment
789 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2011
U.S. locations
2
States / cities
Des Moines, Iowa • Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Nov 4, 2011 · Synced Oct 7, 2026, 4:13 AM EDT
Active, not recruiting Phase 4 Interventional Accepts healthy volunteers

Reward Sensitivity and Pharmacotherapy for Smoking Cessation

NCT02162849
View directory record Official record
Conditions
Tobacco Use Cessation
Interventions
Varenicline, Nicotine Patch, Placebo Patch, Placebo Tablet, Questionnaires, Counseling Sessions, Lab Session, Saliva Test
Drug · Behavioral · Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years to 75 Years
Enrollment
204 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Oct 7, 2026, 4:13 AM EDT
Terminated Not applicable Interventional

Peri-procedural Smoking Cessation Program in Patients With Chronic Pain

NCT04605744
View directory record Official record
Conditions
Chronic Pain, Smoking
Interventions
Smoking cessation counseling
Behavioral
Lead sponsor
The Cooper Health System
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Camden, New Jersey
Source: ClinicalTrials.gov public record
Updated Jan 26, 2022 · Synced Oct 7, 2026, 4:13 AM EDT
Recruiting Not applicable Interventional

Cessation of Dual Use of Cigarettes and E-cigarettes During Pregnancy

NCT07124702
View directory record Official record
Conditions
Dual Use of Cigarettes and E-cigarettes, Gestational Weight Gain, Birth-weight-for-gestational-age z Score
Interventions
Simultaneous cessation intervention, Stepwise cessation intervention, Behavior counseling only
Behavioral
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
18 Years and older · Female only
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Nov 13, 2025 · Synced Oct 7, 2026, 4:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Real Time fMRI and Quitting Smoking

NCT03302026
View directory record Official record
Conditions
Nicotine Use Disorder
Interventions
Realtime biofeedback using fMRI
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 65 Years
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 16, 2019 · Synced Oct 7, 2026, 4:13 AM EDT
Terminated Early Phase 1 Interventional

Bupropion Hydrochloride or Patient's Choice for Smoking Cessation in Patients With Squamous Cell Head and Neck Cancer Undergoing Radiation Therapy With or Without Chemotherapy

NCT02582008
View directory record Official record
Conditions
Current Smoker, Head and Neck Squamous Cell Carcinoma, Hypopharyngeal Squamous Cell Carcinoma, Laryngeal Squamous Cell Carcinoma, Nasopharyngeal Carcinoma, Oral Cavity Squamous Cell Carcinoma, Oropharyngeal Squamous Cell Carcinoma
Interventions
Bupropion Hydrochloride, Laboratory Biomarker Analysis, Nicotine Replacement, Quality-of-Life Assessment, Questionnaire Administration, Varenicline
Drug · Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
2
States / cities
Winston-Salem, North Carolina • Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Mar 22, 2023 · Synced Oct 7, 2026, 4:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

CONNECT: Smoking Cessation and Lung Cancer Screening

NCT04149249
View directory record Official record
Conditions
Smoking Cessation
Interventions
Computer-Assisted Intervention Video Doctor, Computer-Assisted Intervention no Video Doctor
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
55 Years to 80 Years
Enrollment
99 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
2
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 15, 2023 · Synced Oct 7, 2026, 4:13 AM EDT
Completed Not applicable Interventional

Salvation Army Tobacco Quit Line Referral Implementation Trial

NCT06689774
View directory record Official record
Conditions
Tobacco Use, Smoking, Smoking Cessation
Interventions
Cognitive-Motivational Feedback, Staff Tobacco Quit Line Referral Implementation Support, Consumer Incentives for Immediate Referral to a Tobacco Quit Line
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Oct 7, 2026, 4:13 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Smoking Cessation Intervention Development for Homeless Youth

NCT06754215
View directory record Official record
Conditions
Cigarette Smoking-Related Carcinoma
Interventions
Focus Group, Interview, Smoking Cessation Intervention, Survey Administration
Behavioral · Other
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
14 Years to 24 Years
Enrollment
179 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2023
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Oct 7, 2026, 4:13 AM EDT
Completed Not applicable Interventional

Intensive Referral to Reduce Smoking in Probationers

NCT03042650
View directory record Official record
Conditions
Smoking Cessation, Substance Use Disorder
Interventions
Intensive Referral Intervention Group, Standard Practice Facilitated Group
Behavioral
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years and older
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Sep 29, 2023 · Synced Oct 7, 2026, 4:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Contingency Management for Smoking Cessation

NCT04982952
View directory record Official record
Conditions
Smoking Cessation, Smoking, Tobacco, Smoking Reduction
Interventions
Contingency Management - Increasing, Fixed payments
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
83 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
2
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Dec 5, 2024 · Synced Oct 7, 2026, 4:13 AM EDT
Completed Phase 4 Interventional

Centralized Telephone Outreach to Assist Smoking Cessation Among Veterans

NCT00012948
View directory record Official record
Conditions
Smoking, Smoking Cessation
Interventions
Telephone Care
Procedure
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
Not listed
Enrollment
800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 2004
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 7, 2015 · Synced Oct 7, 2026, 4:13 AM EDT
Completed Not applicable Interventional

Smoking Cessation Intervention for Diabetic Patients

NCT01501877
View directory record Official record
Conditions
Smoking, Type 2 Diabetes
Interventions
Acceptance and Commitment Therapy, Standard smoking cessation intervention
Behavioral
Lead sponsor
Rhode Island Hospital
Other
Eligibility
21 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Apr 12, 2017 · Synced Oct 7, 2026, 4:13 AM EDT