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ClinicalTrials.gov public records Last synced Nov 15, 2026, 3:15 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 31 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Challenge Test Clear all

Conditions: Bronchial Asthma
Interventions: Albuterol Sulfate Inhalation Aerosol (90 mcg per actuation), Ventolin HFA 90Mcg/Actuation Inhalation Aerosol_#1, Ventolin HFA, 90 Mcg/Inh Inhalation Aerosol_#2, Placebo; Drug
Lead sponsor: Cipla Ltd.; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Medford, Oregon

Conditions: Cardiovascular Diseases, Hyperlipidemias
Interventions: Lipid Challenge, Glucose Challenge, Mixed Meal Challenge; Dietary Supplement
Lead sponsor: Emory University; Other
Eligibility: 18 Years to 50 Years
Enrollment: 11 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: COPD
Interventions: biological/vaccine; Biological
Lead sponsor: University of South Florida; Other
Eligibility: 19 Years to 92 Years · Male only
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2004 – 2007
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Orthostatic Hypotension
Interventions: Impedance threshold device; Device
Lead sponsor: United States Army Institute of Surgical Research; Federal
Eligibility: 18 Years to 65 Years
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2006
U.S. locations: 1
States / cities: Fort Sam Houston, Texas

Conditions: Randomised Clinical Trial, Double Blind, Dengue, Challenge Test, Dose Escalation and Safety
Interventions: VLPDEN-02 1.0 µg (0.25 µg of each VLP) + ALFQ adjuvant, VLPDEN-02 10 µg (2.5 µg of each VLP) + ALFQ adjuvant, VLPDEN-02 100 µg (25 µg of each VLP) + ALFQ adjuvant, ALFQ adjuvant + Saline, rDEN3Delta30; Biological
Lead sponsor: VLP Therapeutics; Industry
Eligibility: 18 Years to 55 Years
Enrollment: 42 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2027 – 2028
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Allergic Rhinitis
Interventions: Placebo, Allegra, Allegra-D, PF-03654746; Drug
Lead sponsor: Pfizer; Industry
Eligibility: 19 Years to 55 Years
Enrollment: 21 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2008
U.S. locations: 1
States / cities: Omaha, Nebraska

Conditions: Bronchial Asthma
Interventions: 90 mcg Reference Product, 180 mcg Reference Product, 90 mcg Test Product, Placebo; Drug
Lead sponsor: Cipla Ltd.; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 110 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Denver, Colorado

Conditions: Mouse Allergies, Mouse Sensitization
Interventions: Not listed
Lead sponsor: Vanderbilt University; Other
Eligibility: 18 Years to 60 Years
Enrollment: 39 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Allergy, Irritation, Sensitization
Interventions: Not listed
Lead sponsor: Chattem, Inc.; Industry
Eligibility: 16 Years to 79 Years
Enrollment: 224 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012
U.S. locations: 1
States / cities: Fairfield, New Jersey

Conditions: Healthy, Healthy Volunteer, Healthy Volunteers, Healthy Adult, Healthy Male and Female Subjects, Healthy Subjects, Healthy Volunteers Only, Healthy Non-smokers
Interventions: Negative control, Avocado, Fat and fiber addition; Other
Lead sponsor: University of Vermont Medical Center; Other
Eligibility: 21 Years to 65 Years
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Burlington, Vermont

Conditions: Cough Reflex Sensitivity
Interventions: Cosmed QuarkSpiro Dosimeter-Controlled Nebulizer, DeVilbiss 45 Handheld Nebulizer; Device
Lead sponsor: University of Montana; Other
Eligibility: 18 Years to 89 Years
Enrollment: 10 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Missoula, Montana

Conditions: Hypersensitivity
Interventions: Butenafine HCl 1% (BAY1896425); Drug
Lead sponsor: Bayer; Industry
Eligibility: 18 Years to 79 Years
Enrollment: 225 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013
U.S. locations: 1
States / cities: Fairfield, New Jersey

Conditions: Food Hypersensitivity
Interventions: Not listed
Lead sponsor: ORA, Inc.; Industry
Eligibility: 5 Years to 35 Years
Enrollment: 6 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Asthma
Interventions: mannitol; Drug
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years to 80 Years
Enrollment: 66 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2010
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Drug Hypersensitivity, Penicillin Allergy, Antibiotic Allergy
Interventions: Placebo-Controlled Graded Drug Challenge; Drug
Lead sponsor: Montefiore Medical Center; Other
Eligibility: 7 Years and older
Enrollment: 166 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2021
U.S. locations: 1
States / cities: The Bronx, New York

Conditions: Refractory Ascites, Hepatic Hydrothorax, Hepatic Encephalopathy, Cirrhosis
Interventions: Oral glutamine challenge, Psychometric Tests; Other
Lead sponsor: University of Arkansas; Other
Eligibility: 18 Years to 75 Years
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: Little Rock, Arkansas

Conditions: Alzheimer Disease, Mild Cognitive Impairment
Interventions: Pramlintide challenge test; Drug
Lead sponsor: Boston University; Other
Eligibility: 60 Years to 90 Years
Enrollment: 57 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2026
U.S. locations: 3
States / cities: Indianapolis, Indiana • Boston, Massachusetts • Jamaica Plain, Massachusetts

Conditions: Asthma
Interventions: NIOX MINO® Instrument (09-1100); Device
Lead sponsor: Aerocrine AB; Industry
Eligibility: 7 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012
U.S. locations: 8
States / cities: Blue Bell, Pennsylvania • Collegeville, Pennsylvania • Doylestown, Pennsylvania + 5 more

Conditions: Financial Burden, Health Behavior, Social Support
Interventions: The BAJJAJJA intervention; Behavioral
Lead sponsor: University of Utah; Other
Eligibility: 50 Years and older · Female only
Enrollment: 24 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Optimization of Laboratory Procedures
Interventions: Not listed
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 73 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Congenital Sucrase-Isomaltase Deficiency
Interventions: Sucrose Hydrogen Methane Breath Test; Diagnostic Test
Lead sponsor: QOL Medical, LLC; Industry
Eligibility: 18 Years and older
Enrollment: 211 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Culver City, California

Conditions: Food Hypersensitivity
Interventions: Conjunctival Allergen Challenge; Other
Lead sponsor: ORA, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 19 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016
U.S. locations: 1
States / cities: Charlotte, North Carolina

Conditions: History of IgE Dependent Reaction to a Penicillin Product
Interventions: Penicillin skin test kit; Drug
Lead sponsor: AllerQuest LLC; Industry
Eligibility: 18 Years and older
Enrollment: 481 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2013
U.S. locations: 13
States / cities: Homewood, Alabama • Tucson, Arizona • Walnut Creek, California + 10 more

Conditions: Brain Death
Interventions: venous blood gas; Procedure
Lead sponsor: MemorialCare Health System; Other
Eligibility: 1 Week and older
Enrollment: 7 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Long Beach, California

Search by objective public record fields.

BE Study of Albuterol Sulfate Inhalation Aerosol 90 mcg Per Actuation in Patients With Stable Mild Asthma

The Mixed Meal Challenge Study

Human Safety of Capsaicin Inhalation Challenge Testing for Young and Older Men

Impedance Threshold Device Tilt Study

Phase I Study of VLPDEN-02 Dengue Vaccine in Healthy Adults

A Study to Test a New Decongestant in Patients With Allergic Rhinitis Following a Nasal Allergen Challenge

Pharmacodynamic Bioequivalence of Metered Dose Inhalers of Albuterol Sulfate in Patients With Stable Mild Asthma

A Comparison of Skin Prick Tests, Clinical Symptoms, and Nasal Challenge Using a New Mouse Extract

Cumulative Irritation Patch Test

Avocado and Postprandial Responses

Evaluating the Feasibility and Reliability of Using Handheld Nebulizers to Conduct Cough Sensitivity Testing With Citric Acid

Study to Determine Skin Irritation and/or Sensitization Potential of an Antifungal Cream Containing Trolamine (Repeated Insult Patch Test)

Food Allergy Challenge Diagnostic Study

Mannitol Bronchoprovocation Challenge Ancillary Study/ACRN

Drug Challenges Without Prior Skin Testing

Glutamine Challenge as Predictor of Hepatic Encephalopathy After Transjugular Intrahepatic Portosystemic Shunt (TIPS)

Multi-Center Development of a Novel Diagnostic Test for Alzheimer's Disease

A Study to Explore the Utility of Fractional Exhaled Nitric Oxide (FeNO) Compared With Methacholine Challenge (MCC) Testing in the Assessment of Patients With Suspected But Undiagnosed Asthma

Economic Empowerment and Health Promotion of Uganda Grandmother-caregivers.

Optimization of the ex Vivo Challenge

Adult Pilot Study for Reference Ranges and Optimal Cut-offs for the Sucrose Challenge Test and Sucrose Breath Test

Food Allergy Diagnostic Test Response to Previous Oral Challenge Response

Evaluation of Skin Testing Reagents for Penicillin Allergy

Does Venous pCO2 Increase by 20 mmHg or More During Apnea Challenge Test?