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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Chemotherapy-Induced Peripheral Neuropathy Clear all
Completed Not applicable Interventional Results available

Voxx Human Performance Technology Socks for Chemotherapy-Induced Peripheral Neuropathy

NCT04403802
View directory record Official record
Conditions
Neuropathy;Peripheral, Chemotherapy-induced Peripheral Neuropathy, Neuropathy
Interventions
Voxx Human Performance Technology Socks, Placebo Socks
Device
Lead sponsor
Arash Asher, MD
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
2
States / cities
Los Angeles, California • Torrance, California
Source: ClinicalTrials.gov public record
Updated Aug 28, 2025 · Synced Jun 10, 2026, 6:44 AM EDT
Recruiting Phase 3 Interventional

Comparing Cooling and/or Compression Approaches of Limbs for Prevention of Chemotherapy-Induced Peripheral Neuropathy

NCT05642611
View directory record Official record
Conditions
Malignant Solid Neoplasm
Interventions
Biospecimen Collection, Cryocompression Therapy, Pneumatic Compression Therapy, Quality-of-Life Assessment, Questionnaire Administration
Procedure · Other
Lead sponsor
SWOG Cancer Research Network
Network
Eligibility
18 Years and older
Enrollment
777 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2031
U.S. locations
36
States / cities
Birmingham, Alabama • Martinez, California • Fairfield, Connecticut + 32 more
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Jun 10, 2026, 6:44 AM EDT
Enrolling by invitation Not applicable Interventional

Helping Cancer Patients Manage Neuropathy Symptoms From Chemotherapy With a Low-Intensity, Low-Risk Cranial PEMF Device

NCT07061769
View directory record Official record
Conditions
Chemotherapy Induced Peripheral Neuropathy, Chemotherapy Induced Peripheral Neuropathy (CIPN), Chemotherapy Induced Pain Neuropathy, Chemotherapy Induced Neuropathic Pain
Interventions
SHIFT
Device
Lead sponsor
FluxWear, INC
Industry
Eligibility
18 Years to 60 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Newport Beach, California
Source: ClinicalTrials.gov public record
Updated Jul 10, 2025 · Synced Jun 10, 2026, 6:44 AM EDT
Not listed No phase listed Observational

Chemotherapy Induced Peripheral Neuropathy Natural History Study (EPIPHANY)

NCT03997981
View directory record Official record
Conditions
Chemotherapy-induced Peripheral Neuropathy
Interventions
Not listed
Lead sponsor
Disarm Therapeutics
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
10
States / cities
DeBary, Florida • Baltimore, Maryland • Ann Arbor, Michigan + 6 more
Source: ClinicalTrials.gov public record
Updated Feb 29, 2024 · Synced Jun 10, 2026, 6:44 AM EDT
Completed No phase listed Observational

Scrambler Therapy in Treating Pain and Peripheral Neuropathy in Patients Previously Treated With Chemotherapy

NCT01347723
View directory record Official record
Conditions
Pain, Peripheral Neuropathy
Interventions
scrambler therapy, questionnaire administration, management of therapy complications
Other · Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
194 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 13, 2020 · Synced Jun 10, 2026, 6:44 AM EDT
Completed Not applicable Interventional

Whole Body Vibration for the Improvement of Health and Functioning in Participants With Chemotherapy-Induced Peripheral Neuropathy

NCT04170075
View directory record Official record
Conditions
Chemotherapy-Induced Peripheral Neuropathy, Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
Interventions
Whole Body Vibration
Behavioral
Lead sponsor
OHSU Knight Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 29, 2023 · Synced Jun 10, 2026, 6:44 AM EDT
Completed Not applicable Interventional Results available

Breast/Evaluation of Cryotherapy and TRPA1 Receptors in Chemotherapy Induced Neuropathy

NCT03329131
View directory record Official record
Conditions
Peripheral Neuropathies
Interventions
Cryotherapy
Device
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Oct 15, 2024 · Synced Jun 10, 2026, 6:44 AM EDT
Completed Not applicable Interventional

Photobiomodulation Therapy and Nerve Density for Patients With Diabetic or Chemotherapy-associated Neuropathy

NCT03195868
View directory record Official record
Conditions
Neuropathy, Neuropathy, Diabetic, Neuropathy Toxic
Interventions
Realief Therapy
Device
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 8, 2022 · Synced Jun 10, 2026, 6:44 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Alpha-lipoic Acid in Patients at Risk for Paclitaxel Induced Neuropathy

NCT01313117
View directory record Official record
Conditions
Peripheral Neuropathy
Interventions
Alpha lipoic acid
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older · Female only
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 1, 2014 · Synced Jun 10, 2026, 6:44 AM EDT
Terminated Phase 2 Interventional Results available

NR in Chemo-induced Peripheral Neuropathy

NCT03642990
View directory record Official record
Conditions
Chemotherapy-induced Peripheral Neuropathy, Breast Cancer Metastatic, Platinum-resistant Recurrent Ovarian Cancer, Head and Neck Cancer Stage IV, Endometrial Cancer Stage IV
Interventions
Nicotinamide Riboside
Drug
Lead sponsor
Donna Hammond, PhD
Other
Eligibility
18 Years to 85 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
2
States / cities
Iowa City, Iowa • Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 11, 2023 · Synced Jun 10, 2026, 6:44 AM EDT
Completed Not applicable Interventional Results available

MC5-A Scrambler Therapy or TENS Therapy in Treating Patients With Chemotherapy-Induced Peripheral Neuropathy

NCT02722434
View directory record Official record
Conditions
Pain, Peripheral Neuropathy, Tingling
Interventions
Laboratory Biomarker Analysis, MC5-A Scrambler Therapy, Questionnaire Administration, Transcutaneous Electrical Nerve Stimulation
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 11, 2022 · Synced Jun 10, 2026, 6:44 AM EDT
Recruiting No phase listed Observational

Assessing Effect of Spinal Cord Stimulation on Pain and Quality of Life With Chemotherapy-Induced Peripheral Neuropathy

NCT05411523
View directory record Official record
Conditions
Chemotherapy-Induced Peripheral Neuropathy, Hematopoietic and Lymphoid System Neoplasm, Malignant Solid Neoplasm
Interventions
Quality-of-Life Assessment, Questionnaire Administration, Spinal Cord Stimulation
Other · Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 1, 2026 · Synced Jun 10, 2026, 6:44 AM EDT
Completed Phase 2 Interventional

Neotrofin for Treatment of Chemotherapy-Induced Peripheral Neuropathy

NCT00041795
View directory record Official record
Conditions
Peripheral Nervous System Diseases, Chemotherapy-Induced Peripheral Neuropathy
Interventions
leteprinim potassium (Neotrofin)
Drug
Lead sponsor
NeoTherapeutics
Industry
Eligibility
18 Years to 80 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2002
U.S. locations
6
States / cities
Berkeley, California • Burbank, California • Mission Hills, California + 3 more
Source: ClinicalTrials.gov public record
Updated Jun 23, 2005 · Synced Jun 10, 2026, 6:44 AM EDT
Terminated Phase 2 Interventional

A Randomized, Double-Blind, Placebo Controlled, Multicenter, Efficacy and Safety Trial of Single Cycle Tetrodotoxin in the Treatment of Chemotherapy Induced Neuropathic Pain

NCT05359133
View directory record Official record
Conditions
Chemotherapy-induced Neuropathic Pain, Chemotherapy-induced Peripheral Neuropathy
Interventions
Tetrodotoxin, Placebo
Drug
Lead sponsor
Wex Pharmaceuticals Inc.
Industry
Eligibility
21 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
15
States / cities
Santa Ana, California • Santa Rosa, California • Port Charlotte, Florida + 11 more
Source: ClinicalTrials.gov public record
Updated Feb 19, 2025 · Synced Jun 10, 2026, 6:44 AM EDT
Withdrawn Early Phase 1 Interventional

Transcranial Direct Current Stimulation in Reducing Pain in Cancer Patients With Chemotherapy Induced Peripheral Neuropathy

NCT04135326
View directory record Official record
Conditions
Chemotherapy-Induced Peripheral Neuropathy, Malignant Neoplasm
Interventions
Quality-of-Life Assessment, Questionnaire Administration, Transcranial Direct Current Stimulation
Other · Procedure
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 8, 2024 · Synced Jun 10, 2026, 6:44 AM EDT
Completed Not applicable Interventional Results available

Scrambler Therapy in the Treatment of Chronic Chemotherapy-Induced Peripheral Neuropathy

NCT02111174
View directory record Official record
Conditions
Neuropathy
Interventions
Scrambler Therapy, Sham Therapy
Device
Lead sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Other
Eligibility
18 Years and older
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 16, 2018 · Synced Jun 10, 2026, 6:44 AM EDT
Completed No phase listed Observational

Nerve Changes in Patients Who Are Undergoing Chemotherapy or Biological Therapy for Cancer

NCT00281853
View directory record Official record
Conditions
Neurotoxicity, Unspecified Adult Solid Tumor, Protocol Specific
Interventions
management of therapy complications
Procedure
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
21 Years to 85 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 10, 2010 · Synced Jun 10, 2026, 6:44 AM EDT
Terminated Phase 3 Interventional Results available

Preventive Treatment of Oxaliplatin Induced Peripheral Neuropathy in Metastatic Colorectal Cancer (POLAR-M)

NCT03654729
View directory record Official record
Conditions
Colorectal Cancer, Chemotherapy-induced Peripheral Neuropathy
Interventions
Calmangafodipir (2 µmol/kg), Calmangafodipir (5 µmol/kg), Placebo
Drug
Lead sponsor
Egetis Therapeutics
Industry
Eligibility
18 Years and older
Enrollment
291 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
11
States / cities
Fresno, California • Orange City, Florida • Wichita, Kansas + 8 more
Source: ClinicalTrials.gov public record
Updated Dec 16, 2021 · Synced Jun 10, 2026, 6:44 AM EDT
Terminated No phase listed Observational

Risk Prediction of Taxane Chemotherapy-Induced Peripheral Neuropathy

NCT04932031
View directory record Official record
Conditions
Breast Cancer, Chemotherapy-induced Peripheral Neuropathy, Aging
Interventions
Not listed
Lead sponsor
Sapere Bio
Industry
Eligibility
18 Years and older · Female only
Enrollment
123 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
2
States / cities
Birmingham, Alabama • Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 2, 2023 · Synced Jun 10, 2026, 6:44 AM EDT
Terminated Not applicable Interventional Results available

Acupuncture for Chemo-Induced Peripheral Neuropathy in Multiple Myeloma Patients

NCT04770402
View directory record Official record
Conditions
Chemotherapy-induced Peripheral Neuropathy
Interventions
Acupuncture, Standard of Care CIPN management
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 26, 2025 · Synced Jun 10, 2026, 6:44 AM EDT
Completed Not applicable Interventional

Preventing Chemotherapy-Induced Peripheral Neuropathy With Acupuncture (PACT Trial)

NCT05528263
View directory record Official record
Conditions
Acupuncture, Early-stage Breast Cancer, Chemotherapy-induced Peripheral Neuropathy, Breast Cancer Stage I, Breast Cancer Stage II, Breast Cancer Stage III
Interventions
Acupuncture, Nature scenery with a relaxation exercise
Device · Other
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
89 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 23, 2026 · Synced Jun 10, 2026, 6:44 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Spinal Cord Stimulation in Chemotherapy Induced Neuropathy

NCT03764514
View directory record Official record
Conditions
Chemotherapy-induced Peripheral Neuropathy
Interventions
Spinal Cord Stimulator
Device
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 23, 2024 · Synced Jun 10, 2026, 6:44 AM EDT
Completed Not applicable Interventional

Somatic Yoga and Meditation for Cancer Survivors With Pain From Neuropathy

NCT03786055
View directory record Official record
Conditions
Cancer Survivor, Pain, Chemotherapy Induced Peripheral Neuropathy, Function, Fall Risk, Balance, Quality of Life
Interventions
Somatic Yoga and Meditation (SYM)
Behavioral
Lead sponsor
Stockton University
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
2
States / cities
Atlantic City, New Jersey • Pomona, New Jersey
Source: ClinicalTrials.gov public record
Updated Aug 14, 2019 · Synced Jun 10, 2026, 6:44 AM EDT
Completed Not applicable Interventional

Treatment Trial Using Low Level Laser Therapy (LLLT) for Treatment of Chemotherapy Induced Peripheral Neuropathy

NCT01006408
View directory record Official record
Conditions
Peripheral Neuropathy
Interventions
Low Level Laser, Placebo followed by Low Level Laser
Procedure
Lead sponsor
Legacy Health System
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Oct 18, 2012 · Synced Jun 10, 2026, 6:44 AM EDT