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ClinicalTrials.gov public records Last synced Oct 25, 2026, 1:51 AM EDT

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Showing 745–768 of 1,095 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Child Developmental Disorders, Pervasive Clear all
Recruiting Not applicable Interventional Accepts healthy volunteers

Parent-Mediated Intervention Targeting Insistence on Sameness for Autistic Children

NCT06472115
View directory record Official record
Conditions
Autism Spectrum Disorder, Autism
Interventions
Supportive Parenting for Anxious Childhood Emotions (SPACE) for insistence on sameness (IS)
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
6 Years to 11 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Feb 25, 2026 · Synced Oct 25, 2026, 1:51 AM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

Clinical Applications of High-Frequency Oscillations

NCT00600717
View directory record Official record
Conditions
Epilepsy, Migraine, Headache, Pain, Autism, Cerebral Palsy, Brain Development, Traumatic Brain Injury, ADHD - Attention Deficit Disorder With Hyperactivity, Mental Health
Interventions
Not listed
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
1 Day to 69 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2000 – 2027
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 4, 2026 · Synced Oct 25, 2026, 1:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Fit Families Program for Families of Children With Autism Spectrum Disorder

NCT05159102
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
12-week FMS Intervention, Physical Activities & Activity Booklets (via FitFamilies app)
Other · Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
4 Years to 11 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jan 27, 2022 · Synced Oct 25, 2026, 1:51 AM EDT
Completed Not applicable Interventional Results available

Reducing Challenging Behaviors in Children With Autism Through Digital Health

NCT05277194
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
KeepCalm app
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
3 Years to 13 Years
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 16, 2026 · Synced Oct 25, 2026, 1:51 AM EDT
Completed Not applicable Interventional

A Coping Effectiveness Training Intervention for Caregivers of Children With Autism Spectrum: A Feasibility Study

NCT01168284
View directory record Official record
Conditions
Autism Spectrum Disorders
Interventions
Coping Effectiveness Training
Behavioral
Lead sponsor
National Human Genome Research Institute (NHGRI)
NIH
Eligibility
18 Years to 100 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 17, 2019 · Synced Oct 25, 2026, 1:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Learning Enhancement Through Neurostimulation in Autism

NCT02998684
View directory record Official record
Conditions
Autism
Interventions
Active Transcranial Direct Current Stimulation, Sham Transcranial Direct Current Stimulation, PEERS Social Skills Training
Device · Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
14 Years to 17 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 4, 2018 · Synced Oct 25, 2026, 1:51 AM EDT
Not yet recruiting Phase 3 Interventional

A Study of KarXT + KarX-EC for Treatment of Irritability in Children and Adolescents With Autism Spectrum Disorder

NCT07285798
View directory record Official record
Conditions
Irritability Associated With Autism Spectrum Disorder
Interventions
KarXT, KarX-EC, KarXT + KarX-EC Matching Placebo
Drug
Lead sponsor
Bristol-Myers Squibb
Industry
Eligibility
5 Years to 17 Years
Enrollment
176 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
23
States / cities
Phoenix, Arizona • Glendale, California • Los Angeles, California + 19 more
Source: ClinicalTrials.gov public record
Updated Sep 28, 2026 · Synced Oct 25, 2026, 1:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Facebook for Social Skills Training in Autism: Project Rex Connect

NCT02897687
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Facebook Group, Book Club Group
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
12 Years to 20 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated May 9, 2018 · Synced Oct 25, 2026, 1:51 AM EDT
Recruiting Not applicable Interventional

Neural Basis of Social Cognition Deficits

NCT05185128
View directory record Official record
Conditions
Autism Spectrum Disorder, Psychosis, Social Communication
Interventions
PEERS social skills intervention
Behavioral
Lead sponsor
Loma Linda University
Other
Eligibility
12 Years to 18 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Feb 4, 2026 · Synced Oct 25, 2026, 1:51 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Characterization and Natural History of Williams Syndrome and Other Chromosome 7q11.23 Variants

NCT06930417
View directory record Official record
Conditions
Williams Beuren Syndrome, Williams Syndrome, Williams Beuren Region Duplication, Dup7
Interventions
Not listed
Lead sponsor
University of Pennsylvania
Other
Eligibility
Not listed
Enrollment
2,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2045
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Oct 25, 2026, 1:51 AM EDT
Completed Not applicable Interventional

Optimizing Social and Communication Outcomes for Toddlers With Autism

NCT00999778
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Caregiver-Mediated Intervention, Caregiver-Education Intervention
Behavioral
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
18 Months to 36 Months
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 16, 2012 · Synced Oct 25, 2026, 1:51 AM EDT
Completed Not applicable Interventional

Animal-Assisted Therapy in Pediatric Autism Spectrum Disorders

NCT06687850
View directory record Official record
Conditions
Pediatric Autism, Developmental Delay (Disorder), Behavioral Concerns
Interventions
animal assisted therapy
Behavioral
Lead sponsor
University of Arkansas, Fayetteville
Other
Eligibility
3 Years to 21 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Fayetteville, Arkansas
Source: ClinicalTrials.gov public record
Updated Nov 14, 2024 · Synced Oct 25, 2026, 1:51 AM EDT
Withdrawn Phase 1 Interventional Accepts healthy volunteers

Triadic Interactions of Families With Autism and Oxytocin

NCT01912378
View directory record Official record
Conditions
Autism Disorder
Interventions
Oxytocin, Placebo nasal spray
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
7 Years to 60 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jan 16, 2019 · Synced Oct 25, 2026, 1:51 AM EDT
Terminated Phase 1 Interventional Results available

A Study to Investigate the Pharmacokinetics, Safety, and Tolerability of Balovaptan in Children With Autism Spectrum Disorder

NCT04049578
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Balovaptan
Drug
Lead sponsor
Hoffmann-La Roche
Industry
Eligibility
2 Years to 4 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
5
States / cities
Phoenix, Arizona • Staten Island, New York • Cleveland, Ohio + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 14, 2020 · Synced Oct 25, 2026, 1:51 AM EDT
Recruiting Not applicable Interventional

Examining the Effectiveness of the Early Start Denver Model in Community Programs Serving Young Autism

NCT06005285
View directory record Official record
Conditions
Autism
Interventions
Early Start Denver Model (ESDM), Early Intensive Behavioral Intervention (EIBI)
Behavioral
Lead sponsor
University of California, Davis
Other
Eligibility
12 Months and older
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Dec 5, 2025 · Synced Oct 25, 2026, 1:51 AM EDT
Completed Not applicable Interventional

Mobilizing Community Systems to Engage Families in Early Autism Spectrum Disorder (ASD) Detection & Services

NCT02445105
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Autism Navigator Enhanced Practice, Family Engagement plus Autism Navigator
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
Not listed
Enrollment
10,857 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
4
States / cities
Tallahassee, Florida • Atlanta, Georgia • White Plains, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 13, 2022 · Synced Oct 25, 2026, 1:51 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Modulating Temporoparietal Junction Mentalizing-Related Activity in Autism Spectrum Disorder (ASD) Using Transcranial Magnetic Stimulation (TMS)

NCT06214065
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
fMRI, rTMS
Diagnostic Test · Device
Lead sponsor
Yale University
Other
Eligibility
18 Years to 35 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 27, 2026 · Synced Oct 25, 2026, 1:51 AM EDT
Completed Early Phase 1 Interventional Results available

Probiotics for Quality of Life in Autism Spectrum Disorders

NCT02903030
View directory record Official record
Conditions
Autism Spectrum Disorders, Anxiety
Interventions
Maltose (placebo), Visbiome Extra Strength
Drug
Lead sponsor
Ohio State University
Other
Eligibility
3 Years to 12 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 5, 2020 · Synced Oct 25, 2026, 1:51 AM EDT
Recruiting Not applicable Interventional

External Trigeminal Nerve Stimulation for Children With ASD + ADHD to Reduce Elevated Symptoms

NCT07214545
View directory record Official record
Conditions
Attention Deficit Disorder With Hyperactivity (ADHD), Autism Spectrum Disorder (ASD)
Interventions
Trigeminal Nerve Stimulation, Sham Trigeminal Nerve Stimulation
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
7 Years to 14 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 20, 2026 · Synced Oct 25, 2026, 1:51 AM EDT
Completed Phase 4 Interventional Results available

Atomoxetine, Placebo and Parent Management Training in Autism

NCT00844753
View directory record Official record
Conditions
Autism, Pervasive Development Disorder, Asperger's Disorder, Attention Deficit Hyperactivity Disorder
Interventions
atomoxetine, Placebo, Parent Management Training
Drug · Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
5 Years to 14 Years
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
3
States / cities
Rochester, New York • Columbus, Ohio • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 4, 2016 · Synced Oct 25, 2026, 1:51 AM EDT
Not listed No phase listed Observational

Validation of Optical Genome Mapping for the Identification of Constitutional Genomic Variants in a Postnatal Cohort

NCT05295277
View directory record Official record
Conditions
Developmental Disability, Intellectual Disability, Autism Spectrum Disorder, Congenital Anomaly, Fragile X Syndrome, Facioscapulohumeral Muscular Dystrophy 1
Interventions
Standard of care genetic testing group
Other
Lead sponsor
Bionano Genomics
Industry
Eligibility
Not listed
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
8
States / cities
Atlanta, Georgia • Augusta, Georgia • Iowa City, Iowa + 5 more
Source: ClinicalTrials.gov public record
Updated Aug 7, 2023 · Synced Oct 25, 2026, 1:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Autism Adaptive Community-based Treatment to Improve Outcomes Using Navigators (ACTION) Network

NCT03575429
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Engagement Intervention, Engagement + Coaching Intervention
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
12 Months to 24 Months
Enrollment
81 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
3
States / cities
Coral Gables, Florida • Tallahassee, Florida • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 16, 2024 · Synced Oct 25, 2026, 1:51 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

A Comparison of Two School Based Interventions to Manage Anxiety in Autistic Students

NCT05863520
View directory record Official record
Conditions
Autism Spectrum Disorder, Anxiety Disorders, Emotion Regulation
Interventions
Zones of Regulation, Facing Your Fears - School Based
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
7 Years to 15 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 4, 2025 · Synced Oct 25, 2026, 1:51 AM EDT
Not yet recruiting Not applicable Interventional

Using Apollo Neuro in Autistic Children With Self-Injurious Behavior

NCT07648420
View directory record Official record
Conditions
Self-Injurious Behavior, Autism Spectrum Disorder
Interventions
Apollo Neuro device
Device
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
6 Years to 179 Months
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Oct 25, 2026, 1:51 AM EDT