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Showing 1–24 of 35 matching trials from the live ClinicalTrials.gov search.
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Completed Not applicable Interventional

Concurrent Treatment of Substance Abuse and Child Maltreatment

NCT02774525
View directory record Official record
Conditions
Substance Use, Child Maltreatment
Interventions
Reinforcement for drug & alcohol abstinence, Parenting intervention, Treatment as usual (TAU)
Behavioral
Lead sponsor
University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2020
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated May 11, 2021 · Synced Jul 21, 2026, 12:06 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Follow-up Evaluation of Home Nurse Visitation Program for Socially Disadvantaged Women and Their Children

NCT00443586
View directory record Official record
Conditions
Risk Reduction Behavior
Interventions
Developmental Screening, Screening plus Transportation, Screening, Transport, Prenatal Visits, Screen, Transport, Prenatal/Inf Visits
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
27 Years to 35 Years
Enrollment
345 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2021
U.S. locations
1
States / cities
Elmira, New York
Source: ClinicalTrials.gov public record
Updated Jun 9, 2021 · Synced Jul 21, 2026, 12:06 PM EDT
Recruiting Not applicable Interventional

Integrating Systems and Basic Income: Improving Outcomes for Families of Young Children

NCT07261254
View directory record Official record
Conditions
Income, Infant, Newborn, Mothers, Poverty, United States, Healthcare Disparities, Child Care, Child Health, Community Health Workers, Hispanic or Latino, Medicaid, Child Development, Social Services Utilization, Health Services Utilization
Interventions
Community Health Worker, Community Health Worker + Guaranteed Basic Income
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
0 Days and older
Enrollment
2,400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Feb 11, 2026 · Synced Jul 21, 2026, 12:06 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Violence Prevention for Adolescent Girls With Prior Maltreatment

NCT02765048
View directory record Official record
Conditions
PTSD, Depression, Aggression, Victimization
Interventions
GAIN Program
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
12 Years and older
Enrollment
312 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
3
States / cities
Arnold, Missouri • St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated May 5, 2016 · Synced Jul 21, 2026, 12:06 PM EDT
Completed Not applicable Interventional

RESPECT-PLUS: Services for Infants With Prenatal Opiate Exposure

NCT02334111
View directory record Official record
Conditions
Opioid Use Disorder, Neonatal Abstinence Syndrome, Child Development, Child Abuse, Child Neglect
Interventions
RESPECT-Plus
Behavioral
Lead sponsor
Boston Medical Center
Other
Eligibility
Up to 21 Days
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 15, 2017 · Synced Jul 21, 2026, 12:06 PM EDT
Completed Not applicable Interventional Results available

Families Together: Intervention for Reunified Families

NCT04382677
View directory record Official record
Conditions
Child Abuse, Child Neglect
Interventions
Promoting First Relationships ®, Resource & Referral
Behavioral · Other
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
264 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2025
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Jul 21, 2026, 12:06 PM EDT
Active, not recruiting Not applicable Interventional

Fostering Healthy Futures for Teens: An RCT

NCT03707366
View directory record Official record
Conditions
Child Abuse, Child Neglect, Risk Behavior, Delinquency, Mental Health Impairment, Substance Use, Educational Problems, Adolescent Development, Adolescent Behavior, Sexual Behavior, Child Maltreatment
Interventions
FHF-T
Behavioral
Lead sponsor
University of Denver
Other
Eligibility
13 Years to 16 Years
Enrollment
234 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2044
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Jul 21, 2026, 12:06 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Assessing Models of Coordinated Services for Low-Income Children and Their Families

NCT04146974
View directory record Official record
Conditions
Child Development, Family and Household
Interventions
Not listed
Lead sponsor
Mathematica Policy Research, Inc.
Other
Eligibility
Not listed
Enrollment
416 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Oct 30, 2019 · Synced Jul 21, 2026, 12:06 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Local Evaluation of the Saint Francis Ministries Fatherhood FIRE Program

NCT05097833
View directory record Official record
Conditions
Parenting, Parent-Child Relations, Relationship, Marital, Relationship, Family, Relationships, Father-Child, Fathers
Interventions
Enhanced Saint Francis Fatherhood FIRE Program, Services as Usual Saint Francis Fatherhood FIRE Program
Behavioral
Lead sponsor
University of Kansas
Other
Eligibility
18 Years and older · Male only
Enrollment
600 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Lawrence, Kansas
Source: ClinicalTrials.gov public record
Updated Apr 2, 2025 · Synced Jul 21, 2026, 12:06 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

K-ORCA: Testing a Decision Support Tool and Group Process for Selecting Interventions

NCT06375551
View directory record Official record
Conditions
Child Abuse, Decision Making, Child Welfare, Decision Making, Shared, Decision Support Technique, Social Facilitation, Implementation Science, Policy, Organizations, Consensus, Mental Health, Family
Interventions
Optimizing Responses with Collaborative Assessments-Automated (ORCA-A), Optimizing Responses with Collaborative Assessments-Live (ORCA-L)
Behavioral
Lead sponsor
Chestnut Health Systems
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Jul 21, 2026, 12:06 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Age 12 Follow-up of Early Preventive Intervention (Memphis)

NCT00438165
View directory record Official record
Conditions
Child Rearing, Reproductive Behavior, Risk Reduction Behavior
Interventions
home visitation
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
Female only
Enrollment
609 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2012
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Feb 18, 2016 · Synced Jul 21, 2026, 12:06 PM EDT
Completed Not applicable Interventional

Enhancing Permanency in Children and Families

NCT04700696
View directory record Official record
Conditions
Substance Abuse, Substance Use, Child Abuse, Neglect, Child
Interventions
Peer Recovery Support, Family Treatment Drug Court with Medications for Opioid Use Disorders (MOUD), Relational Skill Building based on the Nurturing Parenting Program (NPP)
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
Not listed
Enrollment
117 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 22, 2024 · Synced Jul 21, 2026, 12:06 PM EDT
Completed Not applicable Interventional

Collaborative Care for Infants at Risk

NCT03199326
View directory record Official record
Conditions
Child Abuse, Primary Health Care, Child Welfare
Interventions
Collaborative Care
Other
Lead sponsor
University of Utah
Other
Eligibility
0 Days to 364 Days
Enrollment
468 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Nov 9, 2020 · Synced Jul 21, 2026, 12:06 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Disrupting SRFOH to Improve Substance Use and Mental Health Outcomes for Parents in Rural Regions

NCT06560866
View directory record Official record
Conditions
Substance-Related Disorders
Interventions
Just Care for Families
Behavioral
Lead sponsor
Chestnut Health Systems
Other
Eligibility
Not listed
Enrollment
266 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated May 31, 2026 · Synced Jul 21, 2026, 12:06 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Trial of KEEP-P, a Preventive Intervention for Foster Preschoolers (KEEP-P)

NCT03106636
View directory record Official record
Conditions
Child Behavior
Interventions
KEEP-P+
Behavioral
Lead sponsor
University of Oregon
Other
Eligibility
30 Months to 6 Years
Enrollment
442 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Jul 13, 2020 · Synced Jul 21, 2026, 12:06 PM EDT
Completed Not applicable Interventional Results available

Supporting Parents Program: Intervention for Families in CPS

NCT01332851
View directory record Official record
Conditions
Child Abuse, Child Neglect
Interventions
Promoting First Relationships (PFR), Resource and Referral
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
270 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 6, 2018 · Synced Jul 21, 2026, 12:06 PM EDT
Completed Not applicable Interventional

Cash Transfers to Address Child Welfare Involvement

NCT05857553
View directory record Official record
Conditions
Child Poverty
Interventions
Unconditional Cash Transfer, No Direct Cash Transfer
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
Not listed
Enrollment
450 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 27, 2025 · Synced Jul 21, 2026, 12:06 PM EDT
Completed Not applicable Interventional

Family Telehealth Project for Foster Care Youth

NCT04488523
View directory record Official record
Conditions
Parent-Child Relations, Communication
Interventions
Family-based Telehealth Intervention
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
12 Years and older
Enrollment
93 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Nov 13, 2025 · Synced Jul 21, 2026, 12:06 PM EDT
Completed No phase listed Observational

Age-17 Follow-up of Home Visiting Intervention

NCT00708695
View directory record Official record
Conditions
Antisocial Behavior, Psychopathology, Substance Use, HIV Infections
Interventions
Nurse Home Visiting
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
17 Years to 65 Years
Enrollment
1,880 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2015
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated May 3, 2022 · Synced Jul 21, 2026, 12:06 PM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Testing the CrOss Systems Technical Assistance for Retaining Staff (COSTARS) Model for Improving Staff Retention Among Child Welfare Workers and Peer Supporters, and Implementation of Evidence Based Interventions.

NCT07439783
View directory record Official record
Conditions
Substance Use Disorder, Opioid Use Disorder, Child Maltreatment, Implementation, Peer Recovery Supporters
Interventions
COSTARS, Implementation As Usual
Other
Lead sponsor
Alicia Bunger
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 12, 2026 · Synced Jul 21, 2026, 12:06 PM EDT
Active, not recruiting Not applicable Interventional

Intervention to Enhance Coping and Help-seeking Among Youth in Foster Care

NCT06019377
View directory record Official record
Conditions
Adolescent Behavior, Psychosocial Functioning, Coping Behavior, Help-Seeking Behavior, Utilization, Health Care, Depression, Anxiety, Stress Disorders, Post-Traumatic, Emotion Regulation, Child Welfare
Interventions
Stronger Youth Networks and Coping (SYNC)
Behavioral
Lead sponsor
Portland State University
Other
Eligibility
16 Years to 20 Years
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Jul 21, 2026, 12:06 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Collaborating to Implement Cross-System Interventions in Child Welfare and Substance Use

NCT03931005
View directory record Official record
Conditions
Substance Use, Implementation, Child Maltreatment, System Fragmentation
Interventions
Collaboration Decision Support Guide
Other
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 6, 2026 · Synced Jul 21, 2026, 12:06 PM EDT
Recruiting Not applicable Interventional

Testing Implementation Strategies to Scale-up a Multicomponent Continuum of Service Intervention for Families Involved in Systems With Parental Opioid and Methamphetamine Use

NCT07365293
View directory record Official record
Conditions
Substance Related Disorders
Interventions
Just Care for Families (JCFF), Just Care for Families (JCFF) App, Just Care for Families (JCFF) App Feedback
Behavioral
Lead sponsor
Chestnut Health Systems
Other
Eligibility
Not listed
Enrollment
254 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 16, 2026 · Synced Jul 21, 2026, 12:06 PM EDT
Recruiting Not applicable Interventional

Reducing Parental Substance Use and Enhancing Family Resilience Among Rural Families Through Ohio START

NCT07278427
View directory record Official record
Conditions
Substance Use Disorder (SUD), Rural Health, Family Resilience, Child Maltreatment, Child Well-beiing, Substance Use Recovery
Interventions
Ohio START (Ohio Sobriety, Treatment, and Reducing Trauma)
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Jul 21, 2026, 12:06 PM EDT