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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Chronic Intractable Pain Clear all
Completed Phase 4 Interventional

Restore Claims Characterization Study

NCT00200122
View directory record Official record
Conditions
Chronic Refractory Pain Associated With Failed Back Surgery Syndrome, Epidural Fibrosis, Peripheral Causalgia, Complex Regional Pain Syndrome
Interventions
Spinal Cord Stimulation
Device
Lead sponsor
MedtronicNeuro
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
8
States / cities
Chicago, Illinois • Indianapolis, Indiana • Kansas City, Missouri + 5 more
Source: ClinicalTrials.gov public record
Updated Jan 20, 2009 · Synced Sep 14, 2026, 7:06 PM EDT
Completed Not applicable Interventional Results available

OPTIONS Spinal Cord Stimulation Programming Parameters

NCT02503787
View directory record Official record
Conditions
Pain, Intractable
Interventions
Spinal Cord Stimulation (SCS)
Device
Lead sponsor
MedtronicNeuro
Industry
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
11
States / cities
Scottsdale, Arizona • Chula Vista, California • Wilmington, Delaware + 8 more
Source: ClinicalTrials.gov public record
Updated Sep 18, 2017 · Synced Sep 14, 2026, 7:06 PM EDT
Terminated Phase 4 Interventional Results available

A Study To Evaluate Pregabalin In The Treatment Of Moderate To Severe Chronic Bone Pain Related To Metastatic Cancer

NCT00381095
View directory record Official record
Conditions
Bone Neoplasms, Pain, Intractable, Cancer
Interventions
Pregabalin, Placebo
Drug
Lead sponsor
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Industry
Eligibility
18 Years and older
Enrollment
152 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
8
States / cities
Celebration, Florida • Kissimmee, Florida • Pensacola, Florida + 4 more
Source: ClinicalTrials.gov public record
Updated Jan 19, 2021 · Synced Sep 14, 2026, 7:06 PM EDT
Completed Phase 2 Interventional

A Two-Arm Study Evaluation H.P. Acthar Injection Gel in Treatment of Chronic Migraines

NCT01813591
View directory record Official record
Conditions
Chronic Migraine
Interventions
H.P. Acthar Gel
Drug
Lead sponsor
Dent Neuroscience Research Center
Other
Eligibility
18 Years to 60 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
4
States / cities
Springfield, Missouri • Reno, Nevada • Amherst, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 25, 2018 · Synced Sep 14, 2026, 7:06 PM EDT
Active, not recruiting Phase 4 Interventional

Clinical Trial of MED HF10™ Spinal Cord Stimulation for the Treatment of Chronic Pain

NCT06897280
View directory record Official record
Conditions
Chronic, Intractable Back Pain and/or Leg Pain
Interventions
SCS Device Program Setting
Device
Lead sponsor
Nevro Corp
Industry
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Overland Park, Kansas
Source: ClinicalTrials.gov public record
Updated Jun 28, 2026 · Synced Sep 14, 2026, 7:06 PM EDT
Terminated Phase 2 Interventional Results available

A Safety and Effectiveness Study of Intraspinal Gabapentin (MDT2004) for the Treatment of Chronic Pain

NCT00414466
View directory record Official record
Conditions
Chronic Intractable Pain
Interventions
Intraspinal Gabapentin
Drug
Lead sponsor
MedtronicNeuro
Industry
Eligibility
18 Years to 70 Years
Enrollment
254 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
14
States / cities
Little Rock, Arkansas • Napa, California • Sarasota, Florida + 11 more
Source: ClinicalTrials.gov public record
Updated Aug 22, 2013 · Synced Sep 14, 2026, 7:06 PM EDT
Withdrawn Phase 4 Interventional

Transitioning to a Valve -Gated Intrathecal Drug Delivery System (IDDS)

NCT03876158
View directory record Official record
Conditions
Chronic Pain, Intractable Pain, Back Pain
Interventions
Prometra II Programmable Pump system(Flowonix Medical)
Device
Lead sponsor
Rush University Medical Center
Other
Eligibility
22 Years to 85 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 11, 2020 · Synced Sep 14, 2026, 7:06 PM EDT
Completed Not applicable Interventional Results available

Stimgenics Open-Label, Post Market Study

NCT03606187
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Stimgenics SCS Programming Approach, Standard SCS Programming Approach
Device
Lead sponsor
Stimgenics LLC
Industry
Eligibility
18 Years and older
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Bloomington, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 1, 2021 · Synced Sep 14, 2026, 7:06 PM EDT
Completed No phase listed Observational

Prospective Randomized Feasibility Study Comparing Manual vs. Automatic Position-Adaptive Spinal Cord Stimulation With Surgical Leads

NCT01874899
View directory record Official record
Conditions
Chronic Refractory Low Back and Leg Pain
Interventions
RestoreSensor Neurostimulation
Device
Lead sponsor
Justin Parker Neurological Institute
Other
Eligibility
18 Years to 70 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 6, 2019 · Synced Sep 14, 2026, 7:06 PM EDT
Completed Not applicable Interventional

Post-market, Randomized, Controlled, Prospective Study Evaluating Intrathecal Pain Medication (IT) Versus Conventional Medical Management (CMM) in the Non-cancer, Refractory, Chronic Pain Population

NCT04096391
View directory record Official record
Conditions
Chronic Nonmalignant Pain, Pain, Intractable, Pain, Chronic
Interventions
Flowonix Prometra® II Programmable Infusion System, Pain Medicine
Device · Drug
Lead sponsor
Evolve Restorative Center
Other
Eligibility
22 Years and older
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Santa Rosa, California
Source: ClinicalTrials.gov public record
Updated May 17, 2022 · Synced Sep 14, 2026, 7:06 PM EDT
Completed Not applicable Interventional Results available

High Rate Spinal Cord Stimulation (SCS) for Chronic Pain

NCT01624740
View directory record Official record
Conditions
Chronic Pain
Interventions
Low Rate Stimulation, High Rate Stimulation
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Carlsbad, California
Source: ClinicalTrials.gov public record
Updated Mar 19, 2015 · Synced Sep 14, 2026, 7:06 PM EDT
Completed Phase 1 Interventional

Atkins Diet for Difficult-to-Control Headaches in Teenagers

NCT00181064
View directory record Official record
Conditions
Chronic Daily Headache
Interventions
Modified Atkins diet
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
12 Years to 19 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2009 · Synced Sep 14, 2026, 7:06 PM EDT
Completed Phase 2 Interventional Results available

ACT34-CMI -- Adult Autologous CD34+ Cells

NCT00300053
View directory record Official record
Conditions
Myocardial Ischemia
Interventions
CLBS14 (low-dose), CLBS14 (high-dose), placebo injection
Biological
Lead sponsor
Lisata Therapeutics, Inc.
Industry
Eligibility
21 Years to 80 Years
Enrollment
321 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
26
States / cities
Birmingham, Alabama • Phoenix, Arizona • La Jolla, California + 18 more
Source: ClinicalTrials.gov public record
Updated Jan 25, 2021 · Synced Sep 14, 2026, 7:06 PM EDT
Completed Phase 3 Interventional Results available

Efficacy and Safety of Targeted Intramyocardial Delivery of Auto CD34+ Stem Cells for Improving Exercise Capacity in Subjects With Refractory Angina

NCT01508910
View directory record Official record
Conditions
Chronic Myocardial Ischemia, Refractory Angina Pectoris, Advanced Coronary Heart Disease
Interventions
Auto-CD34+ cells, Placebo: Diluent used to suspend Auto-CD34+ cells, Standard of care
Biological · Other
Lead sponsor
Lisata Therapeutics, Inc.
Industry
Eligibility
21 Years to 80 Years
Enrollment
291 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
41
States / cities
Birmingham, Alabama • Gilbert, Arizona • Phoenix, Arizona + 38 more
Source: ClinicalTrials.gov public record
Updated Dec 18, 2018 · Synced Sep 14, 2026, 7:06 PM EDT
Terminated No phase listed Observational

Quality of Life and Pain Changes Due to DRG Stimulation for Chronic Pain

NCT03417973
View directory record Official record
Conditions
Spinal; Nerve Root, Pain, Pelvic Pain, Regional Pain Syndrome, Chronic Pain Syndrome, Complex Regional Pain Syndromes
Interventions
dorsal root ganglion neuromodulation
Device
Lead sponsor
KM Clinical Research Group
Industry
Eligibility
18 Years to 85 Years
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Murrieta, California
Source: ClinicalTrials.gov public record
Updated Mar 18, 2020 · Synced Sep 14, 2026, 7:06 PM EDT
Terminated Not applicable Interventional Results available

Spinal Cord Stimulation (SCS) for Neuropathic Pain of Back or Lower Extremity

NCT00399841
View directory record Official record
Conditions
Intractable Neuropathic Pain, Pain, Back Pain, Lower Extremity Pain
Interventions
Precision for Spinal Cord Stimulation
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Belleville, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 18, 2020 · Synced Sep 14, 2026, 7:06 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Study on the Safety of BAY1817080 How it is Tolerated and the Way the Body Absorbs, Distributes and Gets Rid of the Study Drug Given to Participants With Moderate Renal Impairment and End Stage Renal Disease Requiring Dialysis Compared With Matched Participants With Normal Renal Function

NCT04471337
View directory record Official record
Conditions
Endometriosis Related Pain, Overactive Bladder, Diabetic Neuropathic Pain, Refractory or Unexplained Chronic Cough
Interventions
BAY1817080
Drug
Lead sponsor
Bayer
Industry
Eligibility
18 Years to 79 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
2
States / cities
Miami, Florida • Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Mar 25, 2024 · Synced Sep 14, 2026, 7:06 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Multi-center Prospective Study Determining the Sustainability of Pain Relief and Psychosocial and Functional Responses When Utilizing a Multiple Waveform Enabled Neurostimulator

NCT03082261
View directory record Official record
Conditions
Chronic Pain, Intractable Pain
Interventions
Prodigy, Prodigy MRI or Proclaim Elite IPG
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
269 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
11
States / cities
Phoenix, Arizona • Scottsdale, Arizona • Tucson, Arizona + 8 more
Source: ClinicalTrials.gov public record
Updated Jul 7, 2021 · Synced Sep 14, 2026, 7:06 PM EDT
Completed Not applicable Interventional

Prometra Post-Approval Study

NCT01854229
View directory record Official record
Conditions
Chronic Pain, Cancer Pain, Intractable Pain, Back Pain
Interventions
Prometra Programmable Intrathecal Infusion Pump
Device
Lead sponsor
Flowonix Medical
Industry
Eligibility
22 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2023
U.S. locations
26
States / cities
La Jolla, California • Santa Barbara, California • Santa Rosa, California + 20 more
Source: ClinicalTrials.gov public record
Updated Oct 17, 2023 · Synced Sep 14, 2026, 7:06 PM EDT
Recruiting Phase 2 Interventional

Investigational Trial to Evaluate XC001 Delivered Via an Cardiac Catheter in Subjects With Chronic Angina.

NCT07048808
View directory record Official record
Conditions
Refractory Angina, Coronary Artery Disease
Interventions
XC001, Sham (No Treatment)
Combination Product
Lead sponsor
XyloCor Therapeutics, Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
14
States / cities
Birmingham, Alabama • Phoenix, Arizona • Atlanta, Georgia + 11 more
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Sep 14, 2026, 7:06 PM EDT
Terminated Not applicable Interventional Results available

Efficacy of the Spinal Cord Stimulation System as Salvage Therapy

NCT00387244
View directory record Official record
Conditions
Pain, Intractable Pain, Chronic Pain
Interventions
Precision for Spinal Cord Stimulation
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Napa, California
Source: ClinicalTrials.gov public record
Updated Dec 16, 2020 · Synced Sep 14, 2026, 7:06 PM EDT
Completed No phase listed Observational

Implantable Systems Performance Registry

NCT00959296
View directory record Official record
Conditions
Spinal Cord Stimulation, Deep Brain Stimulation, Drug Infusion (Implantable Pumps), Sacral Neuromodulation
Interventions
Various
Device
Lead sponsor
MedtronicNeuro
Industry
Eligibility
Not listed
Enrollment
10,981 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2016
U.S. locations
43
States / cities
Huntsville, Alabama • Scottsdale, Arizona • Aliso Viejo, California + 40 more
Source: ClinicalTrials.gov public record
Updated Apr 20, 2017 · Synced Sep 14, 2026, 7:06 PM EDT
Not listed No phase listed Observational

Observational Study of the Impact of Genetic Testing on Healthcare Decisions and Care in Interventional Pain Management

NCT02485795
View directory record Official record
Conditions
Pain, Chronic Pain, Back Pain, Nociceptive Pain, Neuropathic Pain, Musculoskeletal Pain, Neck Pain, Pain, Intractable
Interventions
Observational
Other
Lead sponsor
Proove Bioscience, Inc.
Industry
Eligibility
18 Years and older
Enrollment
50,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
31
States / cities
Prescott, Arizona • Heber Springs, Arkansas • Beverly Hills, California + 24 more
Source: ClinicalTrials.gov public record
Updated May 31, 2017 · Synced Sep 14, 2026, 7:06 PM EDT
Completed Not applicable Interventional

Acupuncture in Treating Mucositis-Related Pain Caused by Chemotherapy in Patients Undergoing Stem Cell Transplantation

NCT00060021
View directory record Official record
Conditions
Cancer
Interventions
acupuncture therapy, management of therapy complications, pain therapy
Procedure
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2003
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 29, 2015 · Synced Sep 14, 2026, 7:06 PM EDT