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ClinicalTrials.gov public records Last synced Jun 11, 2026, 5:54 AM EDT

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Showing 1–23 of 23 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Chronic Low Back and Leg Pain Clear all
Not listed Not applicable Interventional Accepts healthy volunteers

Effect of Spinal Cord Stimulation on Gait and Balance in Chronic Low Back Pain Patients

NCT03586882
View directory record Official record
Conditions
Chronic Low Back Pain, Pain in Leg, Unspecified
Interventions
Spinal Cord Stimulation
Device
Lead sponsor
Texas Back Institute
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Plano, Texas
Source: ClinicalTrials.gov public record
Updated Jul 15, 2018 · Synced Jun 11, 2026, 5:54 AM EDT
Recruiting Not applicable Interventional

Managing Pain Using Optimized Sequences by Adjusting Parameters With Independent Current Control

NCT07190807
View directory record Official record
Conditions
Chronic Pain, Intractable Pain, Low Back Pain, Chronic Low-back Pain, Chronic Leg Pain, Leg Pain
Interventions
Boston Scientific WaveWriter Alpha™ SCS Systems
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
7
States / cities
Greenwood, Colorado • Clermont, Florida • New Orleans, Louisiana + 4 more
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Jun 11, 2026, 5:54 AM EDT
Completed No phase listed Observational

Spinal Cord Stimulation Research Study

NCT00768872
View directory record Official record
Conditions
Chronic Low Back and Leg Pain
Interventions
Not listed
Lead sponsor
MedtronicNeuro
Industry
Eligibility
18 Years and older
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
3
States / cities
Napa, California • Chestnut Hill, Massachusetts • Edina, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 13, 2016 · Synced Jun 11, 2026, 5:54 AM EDT
Completed Not applicable Interventional Results available

Study of PM Modulation Therapy in Trial Phase

NCT03110601
View directory record Official record
Conditions
Chronic Pain
Interventions
Control - Conventional SCS, Test - Stimgenics SCS
Device
Lead sponsor
Stimgenics LLC
Industry
Eligibility
19 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Bloomington, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 15, 2019 · Synced Jun 11, 2026, 5:54 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

A Comparative Study: Non-Surgical Spinal Decompression and Spinal Manipulative Therapy- Utilizing a Quantifiable Musculoskeletal Functional Assessment Risk Analysis Tool (MSDR®) in Patients With Chronic Low Back Pain

NCT00732394
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
MSDR
Other
Lead sponsor
MedAppraise, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
1
States / cities
Clearwater, Florida
Source: ClinicalTrials.gov public record
Updated Aug 11, 2008 · Synced Jun 11, 2026, 5:54 AM EDT
Terminated Not applicable Interventional

SENSE (Subcutaneous and Epidural Neuromodulation System Evaluation) Study

NCT01990287
View directory record Official record
Conditions
Failed Back Surgery Syndrome, Post-Laminectomy Syndrome, Low Back Pain
Interventions
SCS and PNfS, SCS Alone
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
22 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
28
States / cities
Phoenix, Arizona • Scottsdale, Arizona • Little Rock, Arkansas + 24 more
Source: ClinicalTrials.gov public record
Updated Apr 12, 2016 · Synced Jun 11, 2026, 5:54 AM EDT
Recruiting Phase 3 Interventional

Mechanisms of Stimulation for Pain Alleviation

NCT06741579
View directory record Official record
Conditions
Chronic Neuropathic Pain in the Low Back and Legs, Peripheral Nerve Stimulation, Chronic Neuropathic Pain
Interventions
Peripheral Nerve Stimulation, Conventional Care Regimen
Device · Procedure
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
148 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Oct 1, 2025 · Synced Jun 11, 2026, 5:54 AM EDT
Completed Not applicable Interventional

The Feasibility of Using Neuroscience Education in Adults Over 65 Years Old With Chronic Low Back and/or Lower Extremity Pain

NCT02449876
View directory record Official record
Conditions
Back Pain, Lower Extremity Pain
Interventions
Neuroscience Education
Other
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
65 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Apr 11, 2017 · Synced Jun 11, 2026, 5:54 AM EDT
Completed No phase listed Observational

Spinal Cord Stimulation Research Study

NCT00737581
View directory record Official record
Conditions
Chronic Low Back and Leg Pain
Interventions
Not listed
Lead sponsor
MedtronicNeuro
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
2
States / cities
Edina, Minnesota • Garland, Texas
Source: ClinicalTrials.gov public record
Updated Jan 31, 2017 · Synced Jun 11, 2026, 5:54 AM EDT
Terminated Phase 4 Interventional Results available

Percutaneous Neuromodulation Therapy (PNT) With Chronic Low Back Pain Patients

NCT00290238
View directory record Official record
Conditions
Low Back Pain
Interventions
Vertis Percutaneous Neuromodulation Therapy (PNT), Transcutaneous Electrical Nerve Stimulation (TENS)
Device
Lead sponsor
RS Medical
Industry
Eligibility
18 Years and older
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
8
States / cities
La Jolla, California • Atlanta, Georgia • Eugene, Oregon + 5 more
Source: ClinicalTrials.gov public record
Updated May 31, 2009 · Synced Jun 11, 2026, 5:54 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Caudal Epidural Injection of Dextrose For Low Back Pain

NCT01547364
View directory record Official record
Conditions
Back Pain Lower Back Chronic
Interventions
Saline, Dextrose
Drug
Lead sponsor
Smigel, Liza, M.D.
Individual
Eligibility
18 Years to 75 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Hilo, Hawaii
Source: ClinicalTrials.gov public record
Updated Apr 29, 2018 · Synced Jun 11, 2026, 5:54 AM EDT
Completed No phase listed Observational

MIS MiLIF Versus Open

NCT00792129
View directory record Official record
Conditions
Chronic Low Back Pain, Leg Pain
Interventions
The Atavi System
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years to 75 Years
Enrollment
113 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
9
States / cities
La Jolla, California • San Diego, California • Port Charlotte, Florida + 5 more
Source: ClinicalTrials.gov public record
Updated Feb 15, 2012 · Synced Jun 11, 2026, 5:54 AM EDT
Completed Not applicable Interventional

Manual Therapy as a Form of Sensory Discrimination in Chronic Low Back Pain

NCT02757378
View directory record Official record
Conditions
Low Back Pain
Interventions
Neuroplasticity Explanation (Experimental), Biomechanical Explanation (Control)
Procedure
Lead sponsor
Kevin Farrell
Other
Eligibility
18 Years and older
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
5
States / cities
Moline, Illinois • Silvis, Illinois • Woodridge, Illinois + 1 more
Source: ClinicalTrials.gov public record
Updated May 1, 2016 · Synced Jun 11, 2026, 5:54 AM EDT
Completed Not applicable Interventional

Evaluation of the Effectiveness of Transforaminal Epidural Injections in Lumbar Disc Herniation or Radiculitis

NCT01052571
View directory record Official record
Conditions
Low Back Pain
Interventions
lumbar transforaminal epidural injections
Procedure
Lead sponsor
Pain Management Center of Paducah
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Paducah, Kentucky
Source: ClinicalTrials.gov public record
Updated Oct 20, 2015 · Synced Jun 11, 2026, 5:54 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Integrated Supported Biopsychosocial Self-Management for Back Related Leg Pain

NCT05022121
View directory record Official record
Conditions
Low Back Pain, Sciatica, Back Related Leg Pain, Pain, Chronic, Intervertebral Disc Displacement
Interventions
Supported Biopsychosocial Self-Management (SBSM), Medical Care
Behavioral · Drug
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
2
States / cities
Minneapolis, Minnesota • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 14, 2024 · Synced Jun 11, 2026, 5:54 AM EDT
Completed Not applicable Interventional Results available

Making Better Lives: Patient-Focused Care for Low Back Pain (LBP)

NCT02697435
View directory record Official record
Conditions
Chronic Low Back Pain, Hip Ostearthritis, Myofascial Pain Syndrome, Fibromyalgia, Depression, Maladaptive Coping, Lumbar Spinal Stenosis, Insomnia, Sacroiliac Joint Pain, Lateral Hip and Thigh Pain, Anxiety, Dementia, Recent Leg Length Discrepancy
Interventions
Patient-Centered Care, Imaging-Directed Care
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
60 Years to 89 Years
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania • Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 18, 2019 · Synced Jun 11, 2026, 5:54 AM EDT
Completed No phase listed Observational

Prospective Randomized Feasibility Study Comparing Manual vs. Automatic Position-Adaptive Spinal Cord Stimulation With Surgical Leads

NCT01874899
View directory record Official record
Conditions
Chronic Refractory Low Back and Leg Pain
Interventions
RestoreSensor Neurostimulation
Device
Lead sponsor
Justin Parker Neurological Institute
Other
Eligibility
18 Years to 70 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 6, 2019 · Synced Jun 11, 2026, 5:54 AM EDT
Recruiting Not applicable Interventional

How Osteopathic Treatment Affects the Leg and Foot in People With Low Back Pain

NCT07193212
View directory record Official record
Conditions
Chronic Low Back Pain (CLBP)
Interventions
Osteopathic Manipulative Treatment
Other
Lead sponsor
Edward Via Virginia College of Osteopathic Medicine
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Auburn, Alabama
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Jun 11, 2026, 5:54 AM EDT
Completed Not applicable Interventional

Role of Steroids and 10% Hypertonic Sodium Chloride in Adhesiolysis in Post Lumbar Surgery Syndrome Patients

NCT01053572
View directory record Official record
Conditions
Low Back Pain
Interventions
Adhesiolysis
Procedure
Lead sponsor
Pain Management Center of Paducah
Other
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Paducah, Kentucky
Source: ClinicalTrials.gov public record
Updated Apr 24, 2017 · Synced Jun 11, 2026, 5:54 AM EDT
Completed Not applicable Interventional

Treatment of Chronic Low Back and Lower Extremity Pain

NCT00681447
View directory record Official record
Conditions
Low Back Pain
Interventions
Lumbar Interlaminar Epidural, Lumbar Interlaminar Epidural injection
Procedure
Lead sponsor
Pain Management Center of Paducah
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
Paducah, Kentucky
Source: ClinicalTrials.gov public record
Updated Oct 20, 2015 · Synced Jun 11, 2026, 5:54 AM EDT
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

Brain Mechanisms Supporting Cannabis-induced Pain Relief

NCT04982965
View directory record Official record
Conditions
Sciatica, Lumbar Radiculopathy, Lower Back Pain, Degenerative Disc Disease, Chronic Low-back Pain (cLBP), Chronic Low Back and Leg Pain, Back Pain
Interventions
Active Cannabis, Placebo Cannabis
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
21 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Jun 11, 2026, 5:54 AM EDT
Completed Not applicable Interventional Results available

SCS as an Option for Chronic Low Back and/or Leg Pain Instead of Surgery

NCT04676022
View directory record Official record
Conditions
Chronic Pain
Interventions
WaveWriter, Conventional Medical Managament
Device · Other
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
22 Years and older
Enrollment
241 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
23
States / cities
Palm Desert, California • Santa Rosa, California • Greenwood Village, Colorado + 19 more
Source: ClinicalTrials.gov public record
Updated Mar 5, 2025 · Synced Jun 11, 2026, 5:54 AM EDT
Completed Early Phase 1 Interventional

Effectiveness of Caudal Epidural Injections in Treatment of Chronic Low Back and Lower Extremity Pain

NCT00370799
View directory record Official record
Conditions
Low Back Pain
Interventions
Caudal epidural injection, Caudal Epidural Injection with generic Celestone, Caudal Epidural Injection with Celestone, Caudal Epidural Injection with DepoMedrol
Drug
Lead sponsor
Pain Management Center of Paducah
Other
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Paducah, Kentucky
Source: ClinicalTrials.gov public record
Updated Aug 15, 2013 · Synced Jun 11, 2026, 5:54 AM EDT