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ClinicalTrials.gov public records Last synced Oct 2, 2026, 11:20 AM EDT

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Showing 49–72 of 517 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Chronic Low-back Pain Clear all
Terminated Phase 2 Interventional Results available

Long Term Safety Study of Tanezumab in Chronic Low Back Pain

NCT00924664
View directory record Official record
Conditions
Low Back Pain
Interventions
Tanezumab 20 mg, Tanezumab 10 mg
Biological
Lead sponsor
Pfizer
Industry
Eligibility
18 Years and older
Enrollment
849 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
149
States / cities
Anniston, Alabama • Birmingham, Alabama • Hueytown, Alabama + 99 more
Source: ClinicalTrials.gov public record
Updated Apr 21, 2021 · Synced Oct 2, 2026, 11:20 AM EDT
Completed Not applicable Interventional

Individualized Chiropractic and Integrative Care for Low Back Pain

NCT00567333
View directory record Official record
Conditions
Sub-Acute and Chronic Low Back Pain
Interventions
Chiropractic care, Multidisciplinary, integrative care
Other
Lead sponsor
Northwestern Health Sciences University
Other
Eligibility
18 Years and older
Enrollment
201 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2013
U.S. locations
1
States / cities
Bloomington, Minnesota
Source: ClinicalTrials.gov public record
Updated May 12, 2015 · Synced Oct 2, 2026, 11:20 AM EDT
Completed Not applicable Interventional

Mindfulness and Chronic Low Back Pain

NCT03354585
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
mindfulness training, non-mindfulness training, book-listening
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 65 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
2
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Apr 29, 2024 · Synced Oct 2, 2026, 11:20 AM EDT
Completed Phase 4 Interventional

Topical Lidocaine Patch in Low Back Pain

NCT00904540
View directory record Official record
Conditions
Acute and Chronic Non-radicular LBP
Interventions
Lidoderm®
Drug
Lead sponsor
Endo USA Inc., a Keenova Therapeutics Company
Industry
Eligibility
18 Years and older
Enrollment
131 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2002
U.S. locations
7
States / cities
Phoenix, Arizona • Mill Valley, California • Weston, Florida + 4 more
Source: ClinicalTrials.gov public record
Updated Jan 2, 2024 · Synced Oct 2, 2026, 11:20 AM EDT
Completed Not applicable Interventional Results available

Physical Activity Interventions To Heal Chronic Low Back Pain

NCT04678297
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Physical activity + emotion regulation intervention, Physical activity control intervention
Behavioral
Lead sponsor
University of Connecticut
Other
Eligibility
18 Years and older
Enrollment
204 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Storrs Mansfield, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 23, 2026 · Synced Oct 2, 2026, 11:20 AM EDT
Completed Not applicable Interventional

Implementing Group Battlefield Acupuncture in CCRCs for the Treatment of Chronic Lower Back Pain

NCT06128538
View directory record Official record
Conditions
Pain, Back
Interventions
Auricular acupuncture, Visual Analog Scale for Pain, Roland-Morris Disability Questionnaire
Device · Behavioral
Lead sponsor
Korey Kennelty
Other
Eligibility
18 Years to 115 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Aug 28, 2025 · Synced Oct 2, 2026, 11:20 AM EDT
Not listed Not applicable Interventional

The Enso Study for Chronic Low Back Pain

NCT03320863
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Enso device
Device
Lead sponsor
Thimble Bioelectronics, Inc.
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jan 27, 2020 · Synced Oct 2, 2026, 11:20 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Ultrasound Imaging for Myofascial Pain

NCT05928884
View directory record Official record
Conditions
Chronic Low-back Pain, Myofascial Pain
Interventions
There is no intervention. It is a phenotyping study only
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
20 Years to 70 Years
Enrollment
124 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 6, 2025 · Synced Oct 2, 2026, 11:20 AM EDT
Completed Not applicable Interventional Results available

Internet-based Behavioral Pain Management

NCT01918189
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
behavioral pain self-management intervention Pain EASE
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 18, 2019 · Synced Oct 2, 2026, 11:20 AM EDT
Completed Not applicable Interventional

The Feasibility of Using Neuroscience Education in Adults Over 65 Years Old With Chronic Low Back and/or Lower Extremity Pain

NCT02449876
View directory record Official record
Conditions
Back Pain, Lower Extremity Pain
Interventions
Neuroscience Education
Other
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
65 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Apr 12, 2017 · Synced Oct 2, 2026, 11:20 AM EDT
Completed Phase 3 Interventional

Comparison of CAM and Conventional Mind-Body Therapies for Chronic Back Pain

NCT01467843
View directory record Official record
Conditions
Low Back Pain
Interventions
Cognitive Behavioral Therapy, Mindfulness Based Stress Reduction
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
20 Years to 70 Years
Enrollment
342 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 13, 2017 · Synced Oct 2, 2026, 11:20 AM EDT
Not yet recruiting Not applicable Interventional

Magnetic Resonance Elastography Of Chronic Low Back Pain Before And After Therapy

NCT07712458
View directory record Official record
Conditions
Low Back Pain, Recurrent, Chronic Low Back Pain (CLBP)
Interventions
EMMA (Expert Manipulative Massage Automation)
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 17, 2026 · Synced Oct 2, 2026, 11:20 AM EDT
Active, not recruiting Phase 1Phase 2 Interventional

Safety, Tolerability, and Effectiveness of Intramuscular Injection of CELZ-201-DDT for the Treatment of Chronic Lower Back Pain

NCT06053242
View directory record Official record
Conditions
Chronic Low-back Pain, Degenerative Disc Disease
Interventions
CELZ-201-DDT, Placebo
Drug · Other
Lead sponsor
Creative Medical Technology Holdings Inc
Industry
Eligibility
18 Years to 80 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Aventura, Florida
Source: ClinicalTrials.gov public record
Updated Aug 21, 2026 · Synced Oct 2, 2026, 11:20 AM EDT
Completed Not applicable Interventional

Trigger Point Dry Needling vs Trigger Point Dry Needling With Intramuscular Electrical Stimulation

NCT03539588
View directory record Official record
Conditions
Sub-acute and Chronic Low Back Pain
Interventions
trigger point dry needling, Electrical Stimulation
Device
Lead sponsor
William Beaumont Army Medical Center
Federal
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
El Paso, Texas
Source: ClinicalTrials.gov public record
Updated May 29, 2018 · Synced Oct 2, 2026, 11:20 AM EDT
Completed Not applicable Interventional

Acupressure for Fatigue and Low Back Pain

NCT02106741
View directory record Official record
Conditions
Fatigue, Chronic Low Back Pain
Interventions
Relaxation acupressure, Stimulating acupressure
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 65 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 25, 2016 · Synced Oct 2, 2026, 11:20 AM EDT
Suspended Not applicable Interventional Accepts healthy volunteers

Stanford Spine Keeper - Managing Your Low Back Pain

NCT05443503
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Mobile health applications (mHealth apps) based intervention
Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
500,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Redwood City, California
Source: ClinicalTrials.gov public record
Updated Jan 9, 2026 · Synced Oct 2, 2026, 11:20 AM EDT
Completed Phase 2 Interventional Results available

Evaluating the Role of Neuroinflammation in Low Back Pain

NCT03106740
View directory record Official record
Conditions
Low Back Pain, Back Pain With Radiation, Back Pain Without Radiation, Back Pain Lower Back Chronic, Back Ache, Pain, Chronic
Interventions
Minocycline Hydrochloride 100mg Capsule, Magnetic Resonance-Positron Emission Tomography Imaging, Placebo Capsule
Drug · Diagnostic Test · Other
Lead sponsor
Marco Loggia
Other
Eligibility
18 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 11, 2026 · Synced Oct 2, 2026, 11:20 AM EDT
Completed Not applicable Interventional

Program for Emotional and Physical Pain - Pilot Randomized Clinical Trial

NCT01769729
View directory record Official record
Conditions
Depression, Chronic Low Back Pain
Interventions
PEPP, Care management
Behavioral
Lead sponsor
Butler Hospital
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Pawtucket, Rhode Island
Source: ClinicalTrials.gov public record
Updated Dec 5, 2014 · Synced Oct 2, 2026, 11:20 AM EDT
Completed Not applicable Interventional

Meditation and Exercise to Treat Chronic Back Pain

NCT03324659
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Exercise and Meditation, Control
Behavioral
Lead sponsor
Duquesne University
Other
Eligibility
18 Years to 60 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 5, 2021 · Synced Oct 2, 2026, 11:20 AM EDT
Completed Phase 2 Interventional Results available

PF-06372865 In Subjects With Chronic Low Back Pain

NCT02262754
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
PF-06372865, Placebo, Naproxen
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 75 Years
Enrollment
302 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
46
States / cities
Mesa, Arizona • Phoenix, Arizona • Anaheim, California + 36 more
Source: ClinicalTrials.gov public record
Updated Jan 4, 2017 · Synced Oct 2, 2026, 11:20 AM EDT
Recruiting Not applicable Interventional

Photobiomodulation for Lower Back Pain Post Spinal Fusion and Decompression Surgery

NCT06282770
View directory record Official record
Conditions
Spinal Fusion, Chronic Lower Back Pain
Interventions
Laser Diode Brace, Sham Laser Diode Brace
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 75 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
2
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 13, 2026 · Synced Oct 2, 2026, 11:20 AM EDT
Completed Phase 3 Interventional

Mind Body Intervention for Chronic Lower Back Pain

NCT01894282
View directory record Official record
Conditions
Chronic Lower Back Pain
Interventions
Manual Therapy, Mind Body Intervention
Procedure
Lead sponsor
Canandaigua VA Medical Center
Federal
Eligibility
18 Years to 69 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Mar 31, 2022 · Synced Oct 2, 2026, 11:20 AM EDT
Completed Phase 3 Interventional Results available

Study to Evaluate the Efficacy and Safety of Hydrocodone Bitartrate Extended-Release Tablets (CEP-33237) for Relief of Moderate to Severe Pain in Patients With Osteoarthritis or Low Back Pain Who Require Opioid Treatment for an Extended Period of Time

NCT01240863
View directory record Official record
Conditions
Chronic Pain
Interventions
Hydrocodone ER, Placebo
Drug
Lead sponsor
Teva Branded Pharmaceutical Products R&D, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
391 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
73
States / cities
Mobile, Alabama • Chandler, Arizona • Scottsdale, Arizona + 63 more
Source: ClinicalTrials.gov public record
Updated Jun 5, 2017 · Synced Oct 2, 2026, 11:20 AM EDT
Active, not recruiting Not applicable Interventional

Partners4Pain & Wellbeing: A Randomized Trial of Community Supported Complementary and Integrative Health Self-management for Back Pain

NCT06696352
View directory record Official record
Conditions
Chronic Pain, Back Pain, Neck Pain, Self-management, Complementary Therapies
Interventions
Partners4Pain, Keys to Wellbeing
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
376 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated May 12, 2026 · Synced Oct 2, 2026, 11:20 AM EDT