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Showing 1–24 of 267 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Chronic Neuromuscular Pain Clear all
Not listed Phase 3 Interventional

Virtual Reality for Chronic Neuropathic Pain

NCT03592394
View directory record Official record
Conditions
Spinal Cord Injuries, Neuropathic Pain
Interventions
Immersive Virtual Reality (Gear VR)
Device
Lead sponsor
Kathleen Friel
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
White Plains, New York
Source: ClinicalTrials.gov public record
Updated Jul 9, 2019 · Synced Sep 20, 2026, 5:43 AM EDT
Terminated Not applicable Interventional Results available

Spinal Cord Stimulation for Chronic and Intractable Back Pain

NCT00370695
View directory record Official record
Conditions
Back Pain
Interventions
Precision Spinal Cord Stimulation System
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Dec 16, 2020 · Synced Sep 20, 2026, 5:43 AM EDT
Completed Not applicable Interventional

Immersive Virtual Reality for Chronic Neuropathic Pain After Spinal Cord Injury: A Feasibility Trial

NCT04700033
View directory record Official record
Conditions
Neuralgia, Spinal Cord Injuries, Chronic Pain
Interventions
Somatic IVR (sIVR), Distractive IVR (dIVR), Control IVR (cIVR)
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 22, 2022 · Synced Sep 20, 2026, 5:43 AM EDT
Completed No phase listed Observational

Association Between Types of Pain and Motor Activities Physical Activity

NCT05236933
View directory record Official record
Conditions
Spinal Cord Injury, Chronic Pain
Interventions
Not listed
Lead sponsor
Temple University
Other
Eligibility
18 Years to 75 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 13, 2023 · Synced Sep 20, 2026, 5:43 AM EDT
Active, not recruiting Not applicable Interventional

The Effect of Yoga on Nerve Pain Caused by Chemotherapy (Chemotherapy-Induced Peripheral Neuropathy)

NCT05121558
View directory record Official record
Conditions
Chemotherapy-induced Peripheral Neuropathy, Nerve Pain, Neuropathy, Neuropathy, Painful, Pain, CIPN - Chemotherapy-Induced Peripheral Neuropathy, Chronic Pain
Interventions
Yoga, Education control, Usual care
Other
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
227 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
8
States / cities
Boston, Massachusetts • Basking Ridge, New Jersey • Middletown, New Jersey + 5 more
Source: ClinicalTrials.gov public record
Updated Feb 5, 2026 · Synced Sep 20, 2026, 5:43 AM EDT
Recruiting No phase listed Observational

Diabetic Neuropathy in Spinal Cord Stimulator Patients

NCT04687215
View directory record Official record
Conditions
Diabetes Mellitus, Neuropathy, Neuropathic Pain, Vascular Diseases, Vascular Stiffness, Microvascular Changes, Pain, Chronic
Interventions
Not listed
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 4, 2026 · Synced Sep 20, 2026, 5:43 AM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Transvaginal Versus Fluoroscopy-guided Trans Gluteal Pudendal Nerve Block for Pudendal Neuralgia

NCT06644261
View directory record Official record
Conditions
Pudendal Neuralgia, Chronic Pelvic Pain Syndrome
Interventions
Bupivacaine injection
Drug
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2029
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Dec 17, 2024 · Synced Sep 20, 2026, 5:43 AM EDT
Withdrawn Phase 1Phase 2 Interventional

Noninvasive Modulation of Chronic Neuropathic Pain

NCT06249724
View directory record Official record
Conditions
Neuropathic Pain, Chronic Pain
Interventions
Active stimulation using low-frequency ultrasonic transducer, Sham stimulation using low-frequency ultrasonic transducer
Device
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 70 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated May 21, 2025 · Synced Sep 20, 2026, 5:43 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Assessing Symptom and Mood Dynamics in Pain Using the Smartphone Application SOMA

NCT05754190
View directory record Official record
Conditions
Chronic Pain, Acute Pain, Post Operative Pain, Fibromyalgia, Primary, Fibromyalgia, Secondary, Fibromyalgia, Irritable Bowel Syndrome, Chronic Headache Disorder, Chronic Migraine, Chronic Pelvic Pain Syndrome, Temporomandibular Joint Disorders, Endometriosis-related Pain, Arthritis, Chronic Low-back Pain, Failed Back Surgery Syndrome, Post Herpetic Neuralgia, Neuropathic Pain, Painful Diabetic Neuropathy, Painful Bladder Syndrome, Trauma-related Wound, Trauma, Multiple, Chronic Pain Syndrome, Chronic Shoulder Pain
Interventions
SOMA pain manager smartphone application
Device
Lead sponsor
Brown University
Other
Eligibility
18 Years and older
Enrollment
800 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Sep 18, 2025 · Synced Sep 20, 2026, 5:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Lumbopelvic Manipulation on Neuromuscular Activity of Back & Hip Muscles in Adults With Chronic Low Back Pain

NCT01861418
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Lumbopelvic Manipulation, Sham manipulation
Other
Lead sponsor
Texas Woman's University
Other
Eligibility
20 Years to 60 Years
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Oct 11, 2017 · Synced Sep 20, 2026, 5:43 AM EDT
Completed No phase listed Observational

A Study of the Association of Sleep Dysfunction and Burning Mouth Syndrome

NCT00862576
View directory record Official record
Conditions
Burning Mouth Syndrome
Interventions
Not listed
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 16, 2009 · Synced Sep 20, 2026, 5:43 AM EDT
Enrolling by invitation No phase listed Observational

Observational Study of Ketamine Infusions for the Treatment of Chronic Pain

NCT05477004
View directory record Official record
Conditions
Chronic Pain
Interventions
Ketamine
Drug
Lead sponsor
Theresa Lii
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Dec 18, 2025 · Synced Sep 20, 2026, 5:43 AM EDT
Recruiting Not applicable Interventional

Noninvasive Brain Stimulation for Treating Carpal Tunnel Syndrome

NCT04206215
View directory record Official record
Conditions
Chronic Pain, Carpal Tunnel Syndrome
Interventions
transcranial Direct Current Stimulation (tDCS), Transcranial Ultrasound (TUS)
Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 80 Years
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Sep 20, 2026, 5:43 AM EDT
Enrolling by invitation Not applicable Interventional

Efficacy and Feasibility of BurstDR SCS in Painful Diabetic Neuropathy

NCT07250828
View directory record Official record
Conditions
Painful Diabetic Neuropathy (PDN), Diabetic Neuropathy, Neuropathic Pain, Chronic Pain
Interventions
BurstDR Spinal Cord Stimulation
Device
Lead sponsor
TriCity Research Center
Industry
Eligibility
19 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Grand Island, Nebraska
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Sep 20, 2026, 5:43 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Neuroimaging of Opioid Phase (OPAL)

NCT05905419
View directory record Official record
Conditions
Chronic Pain, Opioid Use
Interventions
Opioid Phase
Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older · Female only
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Sep 20, 2026, 5:43 AM EDT
Completed Phase 2 Interventional Results available

Trial of Dronabinol and Vaporized Cannabis in Chronic Low Back Pain

NCT02460692
View directory record Official record
Conditions
Cannabis, Low Back Pain, Neuropathic Pain
Interventions
Placebos, dronabinol, Vaporized Cannabis 3.7% THC/5.6% CBD
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
19 Years to 70 Years
Enrollment
131 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Sep 27, 2023 · Synced Sep 20, 2026, 5:43 AM EDT
Completed Phase 2 Interventional Results available

Clonidine Versus Adenosine to Treat Neuropathic Pain

NCT00349921
View directory record Official record
Conditions
Pain
Interventions
clonidine, adenosine, placebo
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
Not listed
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
2
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 9, 2018 · Synced Sep 20, 2026, 5:43 AM EDT
Withdrawn Phase 2 Interventional

Ketamine and Midazolam Infusions for CRPS: Feasibility Study

NCT05945147
View directory record Official record
Conditions
Complex Regional Pain Syndromes
Interventions
Ketamine, Midazolam, Normal Saline
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2099
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Nov 21, 2024 · Synced Sep 20, 2026, 5:43 AM EDT
Completed No phase listed Observational

Susceptibility to Chronic Post-Traumatic Extremity Pain

NCT00672711
View directory record Official record
Conditions
Chronic Pain
Interventions
Not listed
Lead sponsor
Corewell Health East
Other
Eligibility
18 Years to 80 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
2
States / cities
Royal Oak, Michigan • Troy, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 3, 2020 · Synced Sep 20, 2026, 5:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Mechanisms of Affective Touch in Chronic Pain

NCT04206397
View directory record Official record
Conditions
Fibromyalgia
Interventions
affective touch
Behavioral
Lead sponsor
Laura Case
Other
Eligibility
18 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Oct 1, 2025 · Synced Sep 20, 2026, 5:43 AM EDT
Completed Phase 2 Interventional Results available

Valproic Acid for the Prevention of Post-Amputation Pain

NCT01928849
View directory record Official record
Conditions
Pain, Phantom, Pain, Neuropathic
Interventions
Valproic Acid, Cherry Syrup
Drug · Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
2
States / cities
Bethesda, Maryland • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 18, 2018 · Synced Sep 20, 2026, 5:43 AM EDT
Suspended Not applicable Interventional

Chromatic Retinal Stimulation to Reduce Chronic Pain and Pain Sensitivity

NCT05956067
View directory record Official record
Conditions
Chronic Low-back Pain, Chronic Pain, Fibromyalgia
Interventions
Green Light stimulation, Equal Energy White stimulation, S-cone modulating white light
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 16, 2026 · Synced Sep 20, 2026, 5:43 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

PatientSpot Formerly Known as ArthritisPower

NCT03840928
View directory record Official record
Conditions
Rheumatoid Arthritis, Ankylosing Spondylitis, Fibromyalgia, Gout, Crohn Disease, Juvenile Idiopathic Arthritis, Lupus Erythematosus, Myositis, Osteoarthritis, Osteoporosis, Psoriasis, Psoriatic Arthritis, Scleroderma, Dermatomyositis, Inflammatory Bowel Diseases, Polymyositis, Axial Spondyloarthritis, Diffuse Idiopathic Skeletal Hyperostosis, Polymyalgia Rheumatica, Giant Cell Arteritis, Temporal Arteritis, Wegener, Relapsing Polychondritis, Undifferentiated Connective Tissue Disease, Spinal Cord Injuries, Alzheimer Disease, Amyotrophic Lateral Sclerosis, Ataxia, Bell Palsy, Brain Tumor, Cerebral Aneurysm, Epilepsy, Guillain-Barre Syndrome, Headache, Head Injury, Hydrocephalus, Lumbar Disc Disease, Meningitis, Multiple Sclerosis, Muscular Dystrophy, Neurocutaneous Syndromes, Parkinson Disease, Stroke, Cluster Headache, Tension-Type Headache, Chronic Obstructive Pulmonary Disease, Asthma, Lung Cancer, Cystic Fibrosis, Sleep Apnea, Eczema, Alopecia, Chronic Inflammation, Unstable Angina, Heart Attack, Heart Failure, Arrythmia, Valve Heart Disease, High Blood Pressure, Congenital Heart Disease, Peripheral Arterial Disease, Diabetes, Chronic Liver Disease, Obesity
Interventions
Not listed
Lead sponsor
Global Healthy Living Foundation
Other
Eligibility
19 Years and older
Enrollment
40,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2025
U.S. locations
1
States / cities
Upper Nyack, New York
Source: ClinicalTrials.gov public record
Updated Dec 12, 2023 · Synced Sep 20, 2026, 5:43 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Chronic Pain, Couples, & Physical Activity

NCT04077164
View directory record Official record
Conditions
Chronic Pain, Fibromyalgia, Osteoarthritis, Knee, Osteoarthritis, Hip, Osteoarthritis, Ankylosing Spondylitis, Rheumatoid Arthritis, Chronic Low-back Pain, Chronic Shoulder Pain
Interventions
No intervention, observational only.
Other
Lead sponsor
Illinois Institute of Technology
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 9, 2023 · Synced Sep 20, 2026, 5:43 AM EDT