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ClinicalTrials.gov public records Last synced Nov 15, 2026, 1:11 AM EST

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Showing 97–120 of 164 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Chronic Neuropathic Pain Clear all

Conditions: Chronic Neuropathic Pain, Post-Stroke Pain, Trigeminal Neuralgia, Nerve Injury, Spinal Cord Injuries, Pain, Postoperative, Complex Regional Pain Syndromes, Post-herpetic Neuralgia, Nerve Root Avulsion
Interventions: High Frequency rTMS, Low Frequency rTMS; Device
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years to 80 Years
Enrollment: 32 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Spinal Cord Injuries, Nerve Injury, Pain, Postoperative, Post Herpetic Neuralgia, Complex Regional Pain Syndromes, Post-Stroke Pain, Post Radiation Brain Injury, Post Radiation Plexopathy, Nerve Root Avulsion
Interventions: Medtronic Summit RC+S or Percept RC; Device
Lead sponsor: University of California, San Francisco; Other
Eligibility: 22 Years to 80 Years
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2030
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Complex Regional Pain Syndromes, Healthy
Interventions: Not listed
Lead sponsor: National Institute of Nursing Research (NINR); NIH
Eligibility: 18 Years and older
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2002 – 2014
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Pain
Interventions: clonidine; Drug
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older
Enrollment: 43 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2004 – 2008
U.S. locations: 2
States / cities: Winston-Salem, North Carolina

Conditions: Chronic Pain
Interventions: Ketamine; Drug
Lead sponsor: Theresa Lii; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: Stanford, California

Conditions: Pain, Chronic Pain, Back Pain, Nociceptive Pain, Neuropathic Pain, Musculoskeletal Pain, Neck Pain, Pain, Intractable
Interventions: Observational; Other
Lead sponsor: Proove Bioscience, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 50,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2017
U.S. locations: 31
States / cities: Prescott, Arizona • Heber Springs, Arkansas • Beverly Hills, California + 24 more

Conditions: Chronic Pain, Pain, Chronic, Pain Syndrome, Pain, Neuropathic, Pain, Intractable
Interventions: Mindfulness Based Intervention; Behavioral
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 18 Years to 60 Years
Enrollment: 69 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Human Immunodeficiency Virus, Chronic Neuropathic Pain
Interventions: Low Dose Naltrexone; Drug
Lead sponsor: Emory University; Other
Eligibility: 18 Years to 75 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 3
States / cities: Atlanta, Georgia

Conditions: Neuropathic Pain
Interventions: Donepezil, Placebo; Drug
Lead sponsor: Wake Forest University; Other
Eligibility: 18 Years to 80 Years
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 2
States / cities: Winston-Salem, North Carolina

Conditions: Chronic Pain, Acute Pain, Post Operative Pain, Fibromyalgia, Primary, Fibromyalgia, Secondary, Fibromyalgia, Irritable Bowel Syndrome, Chronic Headache Disorder, Chronic Migraine, Chronic Pelvic Pain Syndrome, Temporomandibular Joint Disorders, Endometriosis-related Pain, Arthritis, Chronic Low-back Pain, Failed Back Surgery Syndrome, Post Herpetic Neuralgia, Neuropathic Pain, Painful Diabetic Neuropathy, Painful Bladder Syndrome, Trauma-related Wound, Trauma, Multiple, Chronic Pain Syndrome, Chronic Shoulder Pain
Interventions: SOMA pain manager smartphone application; Device
Lead sponsor: Brown University; Other
Eligibility: 18 Years and older
Enrollment: 800 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Symptomatic Neuroma, Amputation, Chronic Nerve Pain
Interventions: Axoguard Nerve Cap®; Device
Lead sponsor: Axogen Corporation; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 2
States / cities: Boston, Massachusetts • Lubbock, Texas

Conditions: Burn Injury, Chronic Pain, Pruritus, Itching
Interventions: Transcranial direct current stimulation (tDCS); Device
Lead sponsor: Spaulding Rehabilitation Hospital; Other
Eligibility: 18 Years and older
Enrollment: 34 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2020
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Low Back Pain, Osteoarthritis, Neuropathic Pain
Interventions: EN3409; Drug
Lead sponsor: BioDelivery Sciences International; Industry
Eligibility: 18 Years and older
Enrollment: 304 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 57
States / cities: Birmingham, Alabama • Mobile, Alabama • Phoenix, Arizona + 52 more

Conditions: Spinal Cord Injuries, Neuropathic Pain
Interventions: brivaracetam, Placebo; Drug
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years and older
Enrollment: 44 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Neuropathic Pain, Chronic Pain
Interventions: Ultrasound, Sham (No Treatment); Device
Lead sponsor: Stanford University; Other
Eligibility: 18 Years and older
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Stanford, California

Conditions: Spinal Cord Injuries
Interventions: Brivaracetam, Placebo; Drug · Other
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years and older
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 2
States / cities: Englewood, Colorado • Minneapolis, Minnesota

Conditions: Trigeminal Neuralgia (Burchiel Type I), Trigeminal Neuralgia (Burchiel Type II), Trigeminal Neuropathic Pain, Trigeminal Deafferentation Pain, Complex Regional Pain Syndrome (Types I and II, Involving the Upper Extremity), Glossopharyngeal Neuralgia, Upper Extremity Pain Due to Deafferentation of the Cervical Spine, Central Pain Syndromes
Interventions: Epidural Motor Cortex Stimulation; Device
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Pain
Interventions: ALO-01 (Morphine Sulfate Plus Naltrexone Hydrochloride ER); Drug
Lead sponsor: Pfizer; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 467 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2008
U.S. locations: 58
States / cities: Birmingham, Alabama • Phoenix, Arizona • Tempe, Arizona + 48 more

Conditions: Back Pain
Interventions: Precision Spinal Cord Stimulation System; Device
Lead sponsor: Boston Scientific Corporation; Industry
Eligibility: 18 Years and older
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2008
U.S. locations: 1
States / cities: San Diego, California

Conditions: Chronic, Non-neuropathic Back Pain
Interventions: Mindfulness-Oriented Recovery Enhancement (MORE), Support Group; Behavioral
Lead sponsor: University of Utah; Other
Eligibility: 21 Years to 60 Years
Enrollment: 17 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2019
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Postherpetic Neuralgia
Interventions: T-62; Drug
Lead sponsor: Pfizer; Industry
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
U.S. locations: 8
States / cities: Bradenton, Florida • Naples, Florida • New Port Richey, Florida + 5 more

Conditions: Peripheral Neuropathy, Low Back Pain
Interventions: MC5-A Scrambler Therapy, MC5-A Scrambler Therapy Sham Device; Device
Lead sponsor: Brooke Army Medical Center; Federal
Eligibility: 18 Years to 79 Years
Enrollment: 58 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2017
U.S. locations: 1
States / cities: Fort Sam Houston, Texas

Conditions: Diabetic Neuropathies, Chronic Pain
Interventions: Active Comparator: Active tDCS + Active TUS, Sham; Device
Lead sponsor: Case Western Reserve University; Other
Eligibility: 40 Years to 80 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2027
U.S. locations: 2
States / cities: Chicago, Illinois • Cleveland, Ohio

Conditions: Diabetes Mellitus, Neuropathy, Neuropathic Pain, Vascular Diseases, Vascular Stiffness, Microvascular Changes, Pain, Chronic
Interventions: Not listed
Lead sponsor: University of Chicago; Other
Eligibility: 18 Years and older
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: Chicago, Illinois

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Transcranial Magnetic Stimulation for Chronic Neuropathic Pain

Closed-Loop Deep Brain Stimulation for Refractory Chronic Pain

Study of Proteins Associated With Complex Regional Pain Syndrome

Clonidine-induced Spinal Acetylcholine Release: Normal Volunteers vs. Neuropathic Pain

Observational Study of Ketamine Infusions for the Treatment of Chronic Pain

Observational Study of the Impact of Genetic Testing on Healthcare Decisions and Care in Interventional Pain Management

Investigating Biological Targets, Markers, and Intervention for Chronic Pain

Low Dose Naltrexone for Pain in Patients With HIV

Donepezil Compared to Placebo in Patients With Chronic Neuropathic Pain

Assessing Symptom and Mood Dynamics in Pain Using the Smartphone Application SOMA

Tolerability and Feasibility Pilot Clinical Study of a Large-Diameter Nerve Cap for Protecting and Preserving Terminated Nerve Ends

Effects of Transcranial Direct Current Stimulation (tDCS) on Neuropathic Symptoms Following Burn Injury

Long-term Open-Label Safety Study to Evaluate EN3409

Brivaracetam to Reduce Neuropathic Pain in Chronic SCI: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial

Ultrasound for Peripheral Nerve Modulation

Brivaracetam to Reduce Neuropathic Pain in Chronic Spinal Cord Injury

Motor Cortex Stimulation for the Treatment of Chronic Facial, Upper Extremity, and Throat Pain.

Study of Embeda (Kadian NT, ALO-01) in Subjects With Chronic Moderate to Severe Nonmalignant Pain

Spinal Cord Stimulation for Chronic and Intractable Back Pain

Effects of Behavioral Interventions on Mechanisms of Pain Regulation and Hedonic Regulation

A Study to Determine if an Investigational Pain Medicine Provides Relief of Chronic Pain After a Shingles Outbreak

MC5-A Scrambler Therapy for the Treatment of Chronic Neuropathic Extremity Pain

Optimization of NIBS for Diabetic Neuropathy Neuropathic Pain

Diabetic Neuropathy in Spinal Cord Stimulator Patients