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Showing 1–24 of 25 matching trials from the local directory fallback.
Local D1 index available.
Filters: Condition: Chronic Obstructive Pulmonary Disease (COPD Clear all
Recruiting Phase 3 Interventional

A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00006)

NCT06883305
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease (COPD)
Interventions
Placebo, Tezepelumab
Other · Biological
Lead sponsor
AstraZeneca
Industry
Eligibility
40 Years to 80 Years
Enrollment
990 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
66
States / cities
Foley, Alabama • Mobile, Alabama • Sheffield, Alabama + 56 more
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced May 11, 2026, 2:33 PM EDT
Recruiting Phase 3 Interventional

A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00007)

NCT06878261
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease (COPD)
Interventions
Placebo, Tezepelumab
Other · Biological
Lead sponsor
AstraZeneca
Industry
Eligibility
40 Years to 80 Years
Enrollment
990 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
68
States / cities
Cullman, Alabama • Phoenix, Arizona • Scottsdale, Arizona + 61 more
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced May 11, 2026, 2:33 PM EDT
Recruiting Phase 2 Interventional

A Study to Investigate the Effect of AZD6793 in Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease

NCT07082738
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease (COPD)
Interventions
AZD6793, Placebo
Drug · Other
Lead sponsor
AstraZeneca
Industry
Eligibility
40 Years and older
Enrollment
1,160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
86
States / cities
Birmingham, Alabama • Glendale, Arizona • Phoenix, Arizona + 70 more
Source: ClinicalTrials.gov public record
Updated Mar 16, 2026 · Synced Apr 29, 2026, 10:59 AM EDT
Not yet recruiting Phase 1 Interventional

Investigating Senolytic Properties in Pulmonary Rehabilitation and Metformin in COPD Exacerbations

NCT07275359
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease (COPD)
Interventions
Metformin
Drug
Lead sponsor
Duke University
Other
Eligibility
65 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 16, 2026 · Synced Apr 29, 2026, 9:06 AM EDT
Active, not recruiting Phase 3 Interventional

A Study to Evaluate Astegolimab in Participants With Chronic Obstructive Pulmonary Disease

NCT05595642
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease (COPD)
Interventions
Astegolimab, Placebo
Drug
Lead sponsor
Hoffmann-La Roche
Industry
Eligibility
40 Years to 80 Years
Enrollment
1,290 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
53
States / cities
Birmingham, Alabama • Dothan, Alabama • Glendale, Arizona + 44 more
Source: ClinicalTrials.gov public record
Updated May 19, 2026 · Synced May 21, 2026, 1:52 AM EDT
Active, not recruiting No phase listed Observational

Feasibility and Acceptance of SonoHeal for Airway Clearance and Preliminary Comparison With the Standard of Care

NCT07568119
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease (COPD), Cystic Fibrosis (CF), Non Cystic Fibrosis Bronchiectasis
Interventions
Airway clearance therapy through acoustic oscillations
Device
Lead sponsor
Cognita Labs LLC
Industry
Eligibility
11 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Santa Ana, California
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced May 20, 2026, 6:46 AM EDT
Enrolling by invitation No phase listed Observational

Analysis of the Virtual Acute Care at Home Experience

NCT05952999
View directory record Official record
Conditions
Asthma, Chronic Obstructive Pulmonary Disease (COPD), Bronchitis, Conditions, Diabetes, Fever, Heart Failure, Hypertension, Infections, Renal and Urinary Disorders
Interventions
Digital Care Solution as supportive personalized care, Traditional Hospital Level Care
Other
Lead sponsor
OSF Healthcare System
Other
Eligibility
18 Years and older
Enrollment
9,654 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Peoria, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 16, 2026 · Synced May 20, 2026, 2:29 AM EDT
Completed Not applicable Interventional

Evaluation of Auto-EPAP for Management of Upper Airway Obstruction During Non-Invasive Ventilation

NCT06560411
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease (COPD), Neuromuscular Diseases (NMD), Obesity Hypoventilation Syndrome (OHS), Obstructive Sleep Apnea
Interventions
Non-Invasive Ventilation
Device
Lead sponsor
Breas Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
4
States / cities
Scottsdale, Arizona • San Diego, California • Colorado Springs, Colorado + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 27, 2026 · Synced May 19, 2026, 5:45 PM EDT
Completed Phase 2 Interventional Results available

Tezepelumab COPD Exacerbation Study

NCT04039113
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease (COPD)
Interventions
Placebo, Tezepelumab
Other · Biological
Lead sponsor
AstraZeneca
Industry
Eligibility
40 Years to 80 Years
Enrollment
337 participants
Timeline
2019 – 2024
U.S. locations
27
States / cities
Dothan, Alabama • Huntington Beach, California • Newport Beach, California + 24 more
Source: ClinicalTrials.gov public record
Updated Feb 17, 2025 · Synced Apr 22, 2026, 1:40 PM EDT
Terminated Phase 3 Interventional Results available

Pulmonary Rehabilitation Before Lung Cancer Resection

NCT02887521
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease (COPD), Non-small Cell Lung Cancer (NSCLC)
Interventions
education, pedometer, rehabilitation, surgery
Other · Device · Procedure
Lead sponsor
Alliance for Clinical Trials in Oncology
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
6
States / cities
Jacksonville, Florida • Chicago, Illinois • Detroit, Michigan + 3 more
Source: ClinicalTrials.gov public record
Updated Feb 2, 2025 · Synced Apr 29, 2026, 10:42 AM EDT
Completed Phase 2 Interventional Results available

A Study to Assess the Effect of CK-2127107 on Physical Function in Subjects With Chronic Obstructive Pulmonary Disease

NCT02662582
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease (COPD)
Interventions
Placebo, Reldesemtiv
Drug
Lead sponsor
Astellas Pharma Global Development, Inc.
Industry
Eligibility
40 Years to 75 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
2
States / cities
Torrance, California • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 13, 2024 · Synced May 12, 2026, 8:03 AM EDT
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

Quest to Analyze One Thousand Humans Meditating

NCT06583395
View directory record Official record
Conditions
Amyotrophic Lateral Sclerosis (ALS), Angina, Stable, Anxiety, Asthma, Atrial Fibrillation, Cancer Brain, Cancer Colon, Cancer Prostate, Cancer Skin, Cancer, Breast, Cancer, Lung, Cancer, Other, Cancer, Ovarian, Cancer, Thyroid, Cerebral Palsy, Chronic Fatigue Syndrome, Chronic Kidney Diseases, Chronic Obstructive Pulmonary Disease (COPD), Cluster Headache, Crohn Disease, Deafness, Depression, Diabetes, Eczema, Epilepsy, Fibroids, Fibromyalgia, Heart Failure, Hypertension, Hyperthyroidism, Hypothyroidism, Infertility, Irritable Bowel Syndrome (IBS), Lyme Disease, Lymphoma, Macular Degeneration, Migraine, Multiple Allergies, Multiple Sclerosis, Osteoarthritis, Osteoporosis, Ovarian Cysts, Parkinson Disease, Phantom Limb Pain, Post Traumatic Stress Disorder (PTSD), Psoriasis, Rheumatoid Arthritis, Sjogrens Disease, Spinal Cord Injury, Spinal Stenosis, Stroke, Tension Headache, Throat Cancer, Tinnitus, Ulcerative Colitis
Interventions
Advanced multi-component meditation practice
Behavioral
Lead sponsor
Tobias Moeller-Bertram
Industry
Eligibility
21 Years and older
Enrollment
3,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Palm Desert, California
Source: ClinicalTrials.gov public record
Updated Oct 31, 2024 · Synced May 20, 2026, 11:35 PM EDT
Completed No phase listed Observational Results available

Comparative Effectiveness of Telemedicine in Primary Care

NCT04684836
View directory record Official record
Conditions
Asthma, Chronic Obstructive Pulmonary Disease (COPD), Congestive Heart Failure, Diabetes, Hypertension
Interventions
Exposure to telemedicine, after the onset of the pandemic
Other
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
19 Years and older
Enrollment
33,100 participants
Timeline
2021 – 2022
U.S. locations
4
States / cities
Gainesville, New York • New York, New York • Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Apr 29, 2026, 8:40 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

The CAPTURE Study: Validating a Unique COPD Case Finding Tool in Primary Care (Aim 1)

NCT03581227
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease (COPD)
Interventions
CAPTURE Tool
Other
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
45 Years to 80 Years
Enrollment
4,679 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
8
States / cities
Los Angeles, California • Aurora, Colorado • Miami, Florida + 4 more
Source: ClinicalTrials.gov public record
Updated Jun 6, 2023 · Synced May 6, 2026, 8:45 AM EDT
Terminated Phase 2 Interventional Results available

Pulmonary Rehab in Chronic Obstructive Pulmonary Disease (COPD): Response to Tyvaso

NCT02178566
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease (COPD)
Interventions
Inhaled Treprostinil
Drug
Lead sponsor
Inova Health Care Services
Other
Eligibility
40 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Falls Church, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 11, 2022 · Synced May 6, 2026, 2:05 AM EDT
Completed Not applicable Interventional

Clinical Trial of Air Cleaners to Improve Indoor Air Quality and COPD Health

NCT02236858
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease (COPD)
Interventions
HEPA Air Cleaner, Sham HEPA Air Cleaner
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
40 Years and older
Enrollment
142 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2021
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 13, 2021 · Synced May 7, 2026, 12:13 PM EDT
Completed Not applicable Interventional Results available

Chest Wall Oscillation for Asthma and COPD Exacerbations Trial (COAT)

NCT00181285
View directory record Official record
Conditions
Asthma, Chronic Obstructive Pulmonary Disease (COPD), Undifferentiated Asthma/COPD
Interventions
High Frequency Chest Wall Oscillator
Device
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2008
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 7, 2018 · Synced Apr 29, 2026, 12:48 PM EDT
Completed Phase 4 Interventional Results available

Comparative Effectiveness of a Peer-led O2 Infoline for Patients and Caregivers

NCT02098369
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease (COPD)
Interventions
Additional education material, PELICAN-Proactive, PELICAN-Reactive, Written education material (basic)
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years and older
Enrollment
444 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
6
States / cities
Lake Forest, California • Torrance, California • Denver, Colorado + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 5, 2018 · Synced May 6, 2026, 8:57 AM EDT
Completed Not applicable Interventional Results available

Ex-vivo Perfusion and Ventilation of Lungs Recovered From Non-Heart-Beating Donors to Assess Transplant Suitability

NCT01615484
View directory record Official record
Conditions
Alpha-1 Antitrypsin Deficiency, Bronchiectasis, Chronic Obstructive Pulmonary Disease (COPD), Cystic Fibrosis, Emphysema, Pulmonary Fibrosis, Pulmonary Hypertension, Sarcoidosis
Interventions
STEEN Solution™, Transplantation of lungs obtained from Non-Heart-Beating Donors (NHBDs) after ex-vivo perfusion w/ STEEN Solution™
Device · Procedure
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
15 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
2
States / cities
Chapel Hill, North Carolina • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 7, 2018 · Synced May 19, 2026, 9:01 AM EDT
Completed Not applicable Interventional

Translating The GOLD COPD Guidelines Into Primary Care Practice

NCT01237561
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease (COPD)
Interventions
provider support tools plus spirometer
Other
Lead sponsor
Memorial Hospital of Rhode Island
Other
Eligibility
40 Years to 80 Years
Enrollment
3,593 participants
Timeline
2010 – 2013
U.S. locations
1
States / cities
Pawtucket, Rhode Island
Source: ClinicalTrials.gov public record
Updated Apr 3, 2017 · Synced Apr 22, 2026, 6:14 AM EDT
Completed Phase 2 Interventional

BEAM COPD: Breathing, Education, Awareness and Movement in Chronic Obstructive Pulmonary Disease (COPD)

NCT01551953
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease (COPD)
Interventions
Education, Mind-body breathing, Tai chi
Behavioral
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
40 Years and older
Enrollment
124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 26, 2017 · Synced May 8, 2026, 10:44 PM EDT
Completed Phase 2 Interventional Results available

Pharmacokinetic, Safety and Tolerability Study of Aclidinium/Formoterol Fixed Dose Combination and Formoterol in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)

NCT01551888
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease (COPD)
Interventions
Aclidinium/formoterol 400/12μg, Formoterol
Drug
Lead sponsor
AstraZeneca
Industry
Eligibility
40 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
Spartanburg, South Carolina
Source: ClinicalTrials.gov public record
Updated Feb 13, 2017 · Synced May 20, 2026, 4:09 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Developing a COPD Case Finding Methodology for Primary Care

NCT01880177
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease (COPD)
Interventions
Not listed
Lead sponsor
University of Michigan
Other
Eligibility
40 Years and older
Enrollment
346 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
4
States / cities
Lexington, Kentucky • Ann Arbor, Michigan • Omaha, Nebraska + 1 more
Source: ClinicalTrials.gov public record
Updated May 10, 2016 · Synced May 6, 2026, 5:29 PM EDT
Completed Phase 3 Interventional

Improving Clinician Communication Skills (ICCS)

NCT00687349
View directory record Official record
Conditions
Advanced Cancer, Chronic Obstructive Pulmonary Disease (COPD), Congestive Heart Failure, End Stage Liver Disease, Restrictive Lung Disease
Interventions
Training Program Intervention
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
6,086 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2013
U.S. locations
4
States / cities
Charleston, South Carolina • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Sep 15, 2014 · Synced Apr 29, 2026, 8:40 AM EDT