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ClinicalTrials.gov public records Last synced Oct 1, 2026, 10:35 PM EDT

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Showing 49–72 of 564 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Chronic Pain Patients Clear all
Withdrawn Not applicable Interventional

IVs With Buzzy in Chronic Pain Patients

NCT05555173
View directory record Official record
Conditions
Chronic Pain, Acute Pain
Interventions
Buzzy
Device
Lead sponsor
Steward St. Elizabeth's Medical Center of Boston, Inc.
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 24, 2026 · Synced Oct 1, 2026, 10:35 PM EDT
Completed Not applicable Interventional Results available

Integrated Services for Pain: Interventions to Reduce Pain Effectively

NCT03454555
View directory record Official record
Conditions
Chronic Pain
Interventions
Shared Decision Making, Motivational Interviewing and Cognitive Behavioral Therapy for Chronic Pain
Behavioral
Lead sponsor
RTI International
Other
Eligibility
18 Years to 85 Years
Enrollment
543 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
3
States / cities
Chapel Hill, North Carolina • Durham, North Carolina • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 12, 2025 · Synced Oct 1, 2026, 10:35 PM EDT
Terminated Not applicable Interventional

Acupressure for Pain and Opioid Use Among Breast Cancer Patients

NCT03655600
View directory record Official record
Conditions
Breast Cancer, Fatigue, Chronic Pain
Interventions
Self-administered acupressure
Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older · Female only
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 25, 2019 · Synced Oct 1, 2026, 10:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Neurophysiological Effects on tPCS and tDCS on Healthy Subjects and on Patients With Chronic Visceral Pain

NCT02497196
View directory record Official record
Conditions
Visceral Pain, Pancreatitis, Pelvic Pain
Interventions
Active tPCS, Active tDCS, Sham tPCS, Sham tDCS
Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 60 Years
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 24, 2020 · Synced Oct 1, 2026, 10:35 PM EDT
Terminated Phase 4 Interventional Results available

Percutaneous Neuromodulation Therapy (PNT) With Chronic Low Back Pain Patients

NCT00290238
View directory record Official record
Conditions
Low Back Pain
Interventions
Vertis Percutaneous Neuromodulation Therapy (PNT), Transcutaneous Electrical Nerve Stimulation (TENS)
Device
Lead sponsor
RS Medical
Industry
Eligibility
18 Years and older
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
8
States / cities
La Jolla, California • Atlanta, Georgia • Eugene, Oregon + 5 more
Source: ClinicalTrials.gov public record
Updated Jun 1, 2009 · Synced Oct 1, 2026, 10:35 PM EDT
Completed Phase 3 Interventional

Study to Evaluate the Efficacy and Safety of ORAVESCENT Fentanyl Citrate for the Management of Breakthrough Pain

NCT00214955
View directory record Official record
Conditions
Chronic Neuropathic Pain
Interventions
ORAVESCENT Fentanyl Citrate
Drug
Lead sponsor
Cephalon
Industry
Eligibility
18 Years to 80 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2005
U.S. locations
17
States / cities
Jonesboro, Arkansas • Bakersfield, California • San Diego, California + 13 more
Source: ClinicalTrials.gov public record
Updated May 9, 2014 · Synced Oct 1, 2026, 10:35 PM EDT
Completed Not applicable Interventional Results available

Targeted Interventions to Prevent Chronic Low Back Pain in High Risk Patients

NCT02647658
View directory record Official record
Conditions
Low Back Pain
Interventions
Guideline Based Care plus Psychologically Informed Physical Therapy, Guideline Based Care (GBC)
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
2,300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
5
States / cities
Baltimore, Maryland • Boston, Massachusetts • Pittsburgh, Pennsylvania + 2 more
Source: ClinicalTrials.gov public record
Updated Feb 10, 2020 · Synced Oct 1, 2026, 10:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pain Avoidance Behavior and Its Relation to Risk for Opioid Use in Chronic Pain Patients

NCT04603417
View directory record Official record
Conditions
Chronic Pain, Opioid Use
Interventions
Electroencephalography (EEG)/Magnetoencephalography (MEG)/MRI
Diagnostic Test
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
63 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 27, 2025 · Synced Oct 1, 2026, 10:35 PM EDT
Completed Phase 3 Interventional Results available

Opioid Titration Order Sheet or Standard Care in Treating Patients With Cancer Pain

NCT00666211
View directory record Official record
Conditions
Brain and Central Nervous System Tumors, Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Lymphoproliferative Disorder, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Neoplasms, Pain, Precancerous Condition, Unspecified Adult Solid Tumor, Protocol Specific
Interventions
educational intervention, Titrated pain management, questionnaire administration
Other
Lead sponsor
Vanderbilt-Ingram Cancer Center
Other
Eligibility
21 Years and older
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
11
States / cities
Hopkinsville, Kentucky • Owensboro, Kentucky • Chattanooga, Tennessee + 4 more
Source: ClinicalTrials.gov public record
Updated Sep 6, 2012 · Synced Oct 1, 2026, 10:35 PM EDT
Completed Phase 3 Interventional Results available

16 Week Efficacy and 5 Year Long Term Efficacy, Safety and Tolerability of Secukinumab in Patients With Active Ankylosing Spondylitis

NCT01649375
View directory record Official record
Conditions
Anklyosing Spondylitis
Interventions
Secukinumab (75 mg), Placebo, Secukinumab (150 mg)
Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
219 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
10
States / cities
Mesa, Arizona • Upland, California • Edina, Minnesota + 6 more
Source: ClinicalTrials.gov public record
Updated Oct 30, 2019 · Synced Oct 1, 2026, 10:35 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Positron Emission Tomography to Measure Pain and Pain Control

NCT00001307
View directory record Official record
Conditions
Healthy, Hyperalgesia, Pain, Peripheral Nervous System Disease
Interventions
Oxygen-15 Water, Capsaicin
Drug
Lead sponsor
National Institute of Dental and Craniofacial Research (NIDCR)
NIH
Eligibility
Not listed
Enrollment
273 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1992 – 2005
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 1, 2026, 10:35 PM EDT
Completed Phase 2 Interventional Results available

RN624 In Adult Patients With Chronic Low Back Pain

NCT00584870
View directory record Official record
Conditions
Low Back Pain
Interventions
Naproxen, Placebo, PF-04383119 (RN624)
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 90 Years
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
38
States / cities
Anniston, Alabama • Birmingham, Alabama • Chandler, Arizona + 30 more
Source: ClinicalTrials.gov public record
Updated Jul 12, 2021 · Synced Oct 1, 2026, 10:35 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Prospective Randomized Trial of CPAP for SDB in Patients Who Use Opioids

NCT04928157
View directory record Official record
Conditions
Sleep Disorder; Breathing-Related, Pain, Sleep Apnea, Obstructive Sleep Apnea, Sleep, Sleep Disorder, Chronic Pain, Opioid Use
Interventions
Positive Airway Pressure (PAP)
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
62 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Dec 2, 2024 · Synced Oct 1, 2026, 10:35 PM EDT
Not yet recruiting Phase 2 Interventional

Semaglutide for Low Back Pain

NCT07731256
View directory record Official record
Conditions
Lower Back Pain, Obesity (BMI>30), Chronic Lower Back Pain, glp1 Agonist
Interventions
Semaglutide (administered by PDS290 pen-injector), Placebo (administered by PDS290 pen-injector)
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 85 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2031
U.S. locations
2
States / cities
Birmingham, Alabama • St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 28, 2026 · Synced Oct 1, 2026, 10:35 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Quantitative Ultrasound Biomarkers to Assess Upper Trapezius Muscles in Patients With Chronic Pain

NCT05497622
View directory record Official record
Conditions
Chronic Neck Pain
Interventions
Quantitative Ultrasound, Osteopathic TART Assessment, Osteopathic Manipulation Treatment
Diagnostic Test · Procedure
Lead sponsor
Rocky Vista University, LLC
Other
Eligibility
18 Years and older
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Ivins, Utah
Source: ClinicalTrials.gov public record
Updated Aug 25, 2022 · Synced Oct 1, 2026, 10:35 PM EDT
Completed Not applicable Interventional

Valdecoxib in Treating Chronic Pain in Cancer Patients

NCT00021996
View directory record Official record
Conditions
Pain, Unspecified Adult Solid Tumor, Protocol Specific
Interventions
valdecoxib
Drug
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2004
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 18, 2013 · Synced Oct 1, 2026, 10:35 PM EDT
Completed Phase 1 Interventional

Mindfulness-Oriented Recovery Enhancement for Chronic Pain Patients Receiving Opioid Therapy

NCT01505101
View directory record Official record
Conditions
Chronic Pain, Opioid Abuse, Unspecified Use
Interventions
Mindfulness-Oriented Recovery Enhancement, Conventional Support Group (SG)
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
18 Years and older
Enrollment
115 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Aug 6, 2014 · Synced Oct 1, 2026, 10:35 PM EDT
Completed Not applicable Interventional Results available

Bioness® StimRouter™ Neuromodulation System for Chronic Pain Therapy

NCT01592344
View directory record Official record
Conditions
Chronic Pain
Interventions
StimRouter - active stimulation, StimRouter - Control
Device
Lead sponsor
Bioness Inc
Industry
Eligibility
22 Years and older
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
13
States / cities
Scottsdale, Arizona • Napa, California • Pasadena, California + 10 more
Source: ClinicalTrials.gov public record
Updated Apr 11, 2016 · Synced Oct 1, 2026, 10:35 PM EDT
Completed Phase 3 Interventional Results available

A Study for Patient With Chronic Low Back Pain

NCT00767806
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Duloxetine, Placebo
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years and older
Enrollment
401 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
7
States / cities
Chandler, Arizona • Cromwell, Connecticut • DeLand, Florida + 4 more
Source: ClinicalTrials.gov public record
Updated Oct 18, 2010 · Synced Oct 1, 2026, 10:35 PM EDT
Completed No phase listed Observational

Stellate Ganglion Block to Treat Long COVID 19 Case Series

NCT05812209
View directory record Official record
Conditions
Long COVID, Long Covid19, Post-COVID-19 Syndrome, Post Acute COVID-19 Syndrome, Dysautonomia, Anosmia, Dysgeusia, Brain Fog, Muscle Pain, Shortness of Breath, Dizziness, Fatigue Post Viral, Cough, Menstrual Cycle Abnormal, Pain
Interventions
Stellate Ganglion Block
Procedure
Lead sponsor
Metamorphosis LTD
Other
Eligibility
Not listed
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Cañon City, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 13, 2023 · Synced Oct 1, 2026, 10:35 PM EDT
Completed Not applicable Interventional

Virtual Reality, Debriefing and Chronic Pain

NCT05254509
View directory record Official record
Conditions
Chronic Pain
Interventions
Occupational Therapy, Occupational Therapy +Virtual Reality
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 11, 2025 · Synced Oct 1, 2026, 10:35 PM EDT
No Longer Available No phase listed Expanded access

The Effect of Adding Magnesium Sulfate to Standard Epidural and Interscalene Block in Treatment of Patients With Chronic Pain

NCT01918514
View directory record Official record
Conditions
Pain
Interventions
Adding Magnesium Sulfate to the standard epidural and interscalene blocks for chronic pain
Drug
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
18 Years and older
U.S. locations
1
States / cities
East Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Oct 22, 2021 · Synced Oct 1, 2026, 10:35 PM EDT
Completed Phase 2 Interventional Results available

A Phase 2 Study to Evaluate the Efficacy and Safety of TNX-102 SL in Patients With Multi-Site Pain Associated With Post-Acute Sequelae of SARS-CoV-2 Infection

NCT05472090
View directory record Official record
Conditions
Post-Acute Sequelae of SARS-CoV-2 (PASC) Infection, COVID-19, Long COVID, Long Haul COVID
Interventions
TNX-102 SL, Placebo SL Tablet
Drug
Lead sponsor
Tonix Pharmaceuticals, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
29
States / cities
Birmingham, Alabama • Oceanside, California • Santa Ana, California + 25 more
Source: ClinicalTrials.gov public record
Updated Nov 26, 2024 · Synced Oct 1, 2026, 10:35 PM EDT
Completed Phase 3 Interventional Results available

ß-SPECIFIC 4 Patients: Study of Pediatric EffiCacy and Safety wIth FIrst-line Use of Canakinumab

NCT02296424
View directory record Official record
Conditions
Systemic Juvenile Idiopathic Arthritis (SJIA)
Interventions
ACZ885 150 mg (Canakinumab)
Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
2 Years to 20 Years
Enrollment
182 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
2
States / cities
Los Angeles, California • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 9, 2019 · Synced Oct 1, 2026, 10:35 PM EDT