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ClinicalTrials.gov public records Last synced Oct 9, 2026, 5:24 PM EDT

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Showing 97–120 of 564 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Chronic Pain Patients Clear all
Completed Not applicable Interventional Results available

Chiropractic Management of Chronic Lower Back Pain in Older Adults

NCT00475787
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Spinal Manipulation, Detuned Ultrasound
Procedure
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
65 Years and older
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
2
States / cities
Buffalo, New York • Canandaigua, New York
Source: ClinicalTrials.gov public record
Updated Dec 30, 2014 · Synced Oct 9, 2026, 5:24 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Multimodal Assessment of Sensory Processing and Brain Features in Patients With Chronic Orofacial Pain

NCT02630771
View directory record Official record
Conditions
Toothache, Temporomandibular Joint Disorders
Interventions
Pressure pain threshold
Procedure
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated May 2, 2019 · Synced Oct 9, 2026, 5:24 PM EDT
Completed Not applicable Interventional Results available

A Patient-Centered Intervention to Improve Opioid Safety

NCT02791399
View directory record Official record
Conditions
Opioid Safety, Prescription Opioid Misuse, Chronic Pain
Interventions
ISOP Intervention with the Nurse Care Manager
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
286 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jul 27, 2023 · Synced Oct 9, 2026, 5:24 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Positron Emission Tomography to Measure Pain and Pain Control

NCT00001307
View directory record Official record
Conditions
Healthy, Hyperalgesia, Pain, Peripheral Nervous System Disease
Interventions
Oxygen-15 Water, Capsaicin
Drug
Lead sponsor
National Institute of Dental and Craniofacial Research (NIDCR)
NIH
Eligibility
Not listed
Enrollment
273 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1992 – 2005
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 9, 2026, 5:24 PM EDT
Completed Not applicable Interventional Results available

ECAP-controlled, Closed-loop Stimulation to Treat Chronic Trunk and/or Limb Pain (ECAP)

NCT04319887
View directory record Official record
Conditions
Chronic Pain, Back Pain, Pain
Interventions
Evoke Spinal Cord Stimulation (SCS) System
Device
Lead sponsor
Saluda Medical Pty Ltd
Industry
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
22
States / cities
Little Rock, Arkansas • Carlsbad, California • Santa Rosa, California + 18 more
Source: ClinicalTrials.gov public record
Updated Dec 31, 2024 · Synced Oct 9, 2026, 5:24 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Study of D-Methadone in Patients With Chronic Pain

NCT00588640
View directory record Official record
Conditions
Pain, Bladder Cancer, Breast Cancer, CNS Cancer, Colon Cancer, Esophageal Cancer, Pancreatic Cancer, Prostate Cancer, Uterine Cancer, Head and Neck Cancer, Eye Cancer, Otorhinolaryngologic Neoplasms
Interventions
D-methadone, placebo
Drug
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 10, 2016 · Synced Oct 9, 2026, 5:24 PM EDT
Completed Phase 3 Interventional

The Safety and Efficacy of the Buprenorphine Transdermal Delivery System in Subjects With Osteoarthritis Pain.

NCT00315848
View directory record Official record
Conditions
Osteoarthritis
Interventions
Buprenorphine transdermal delivery system
Drug
Lead sponsor
Purdue Pharma LP
Industry
Eligibility
18 Years and older
Enrollment
225 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1996 – 1999
U.S. locations
10
States / cities
Huntsville, Alabama • Phoenix, Arizona • Westminster, Colorado + 6 more
Source: ClinicalTrials.gov public record
Updated May 3, 2006 · Synced Oct 9, 2026, 5:24 PM EDT
Completed Not applicable Interventional

Stress and Health Interview for Primary Care Patients With Medically Unexplained Symptoms

NCT02151500
View directory record Official record
Conditions
Somatoform Disorders
Interventions
Stress and Health Interview
Behavioral
Lead sponsor
Wayne State University
Other
Eligibility
18 Years to 80 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Rochester Hills, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 8, 2015 · Synced Oct 9, 2026, 5:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Using Music During Lumbar Medial Branch Block Procedure

NCT04091607
View directory record Official record
Conditions
Lower Back Pain, Lumbar Spondylosis
Interventions
Music Therapy
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 10, 2022 · Synced Oct 9, 2026, 5:24 PM EDT
Completed No phase listed Observational

Tracking Outcomes in Pain Patients Using Fitness Devices

NCT02420457
View directory record Official record
Conditions
Chronic Pain, Back Pain
Interventions
Epidural injection, Epidural steroid injection as determined by routine care provider
Procedure · Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 25, 2019 · Synced Oct 9, 2026, 5:24 PM EDT
Completed Not applicable Interventional

Stimulation Change Effects on Quantitative Sensory Testing in Neuromodulation Patients

NCT04708392
View directory record Official record
Conditions
Chronic Pain
Interventions
Spinal Cord Stimulator
Device
Lead sponsor
Albany Medical College
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Albany, New York
Source: ClinicalTrials.gov public record
Updated Jan 15, 2021 · Synced Oct 9, 2026, 5:24 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Study to Demonstrate That Muscle Pattern Recognition (MPR) is an Effective Evaluation Tool for Musculoskeletal Neck or Back Pain

NCT00134225
View directory record Official record
Conditions
Neck Pain, Low Back Pain
Interventions
Muscle Pattern Recognition (MPR)
Device
Lead sponsor
iTech Medical, Inc.
Industry
Eligibility
18 Years to 62 Years
Enrollment
480 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2006
U.S. locations
3
States / cities
Irvine, California • Portage, Michigan • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Oct 26, 2005 · Synced Oct 9, 2026, 5:24 PM EDT
Completed No phase listed Observational Results available

Assessing Pain, Patient Reported Outcomes and Complementary and Integrative Health

NCT05097521
View directory record Official record
Conditions
Chronic Musculoskeletal Pain
Interventions
Practitioner-delivered CIH therapies, Combination of practitioner-delivered and self-care CIH therapies, Self-care CIH therapies
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 89 Years
Enrollment
3,603 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
2
States / cities
Sepulveda, California • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Oct 9, 2026, 5:24 PM EDT
Completed Not applicable Interventional Results available

Trial on the Effect of Optically Modified Fiber Mattress Covers on Sleep Disturbances in Patients With Chronic Back Pain

NCT00969540
View directory record Official record
Conditions
Back Pain, Insomnia
Interventions
Active Mattress Cover, Placebo Mattress Cover
Device
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Dec 3, 2014 · Synced Oct 9, 2026, 5:24 PM EDT
Enrolling by invitation Not applicable Interventional

Using Virtual Reality Applications for Younger Patients With Chronic Pain

NCT07630350
View directory record Official record
Conditions
Chronic Pain Management
Interventions
Virtual reality gaming, Physical therapy exercises
Device · Other
Lead sponsor
Elizabeth Pickle
Other
Eligibility
7 Years to 21 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Allison Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 31, 2026 · Synced Oct 9, 2026, 5:24 PM EDT
Completed Not applicable Interventional Results available

Mobile-Based Contingency Management to Promote Daily Self-monitoring in Primary Care Patients

NCT03962491
View directory record Official record
Conditions
Pain, Chronic
Interventions
Daily Self-Monitoring Surveys + Contingency Management, Daily Self-Monitoring Surveys
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Dec 7, 2022 · Synced Oct 9, 2026, 5:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

TENS for Testicular Pain (ICO): A Randomized Controlled Trial

NCT04866784
View directory record Official record
Conditions
Pain Management
Interventions
Transcutaneous Electrical Nerve Stimulation (TENS)
Device
Lead sponsor
Jennifer E. Lee
Other
Eligibility
18 Years to 99 Years · Male only
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jun 23, 2022 · Synced Oct 9, 2026, 5:24 PM EDT
Active, not recruiting Not applicable Interventional

Pain Self-Management and Treatment Engagement for Patients Taking Opioids

NCT06855732
View directory record Official record
Conditions
Chronic Pain, Opioid Use Disorder, Opioid Misuse and Addiction
Interventions
Usual Care, Pain Self-Management
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
204 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
17
States / cities
Baltimore, Maryland • Allison Park, Pennsylvania • Blawnox, Pennsylvania + 9 more
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Oct 9, 2026, 5:24 PM EDT
Terminated Not applicable Interventional

Patient Experience Comparing Tonic Vs. Burst Spinal Cord Stimulation For Chronic Pain

NCT04159753
View directory record Official record
Conditions
Chronic Pain
Interventions
Spinal Cord Stimulator
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 18, 2022 · Synced Oct 9, 2026, 5:24 PM EDT
Not listed Phase 1 Interventional

New Approaches in Evaluating Patients' Response to Botulinum Toxins in the Treatment of Chronic Neck Pain and Back Pain

NCT02008136
View directory record Official record
Conditions
Cervicalgia, Low Back Pain
Interventions
Botulinum Toxins
Drug
Lead sponsor
VA Connecticut Healthcare System
Federal
Eligibility
18 Years to 85 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Dec 7, 2017 · Synced Oct 9, 2026, 5:24 PM EDT
Completed No phase listed Observational

Diagnosis and Evaluation of Patients Needing Third Molar (Wisdom Tooth) Extraction and Patients With Chronic Facial Pain

NCT00001600
View directory record Official record
Conditions
Facial Pain, Temporomandibular Joint Disorder
Interventions
Not listed
Lead sponsor
National Institute of Dental and Craniofacial Research (NIDCR)
NIH
Eligibility
Not listed
Enrollment
4,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1997 – 2005
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 9, 2026, 5:24 PM EDT
Terminated Not applicable Interventional Results available

Efficacy of the Spinal Cord Stimulation System as Salvage Therapy

NCT00387244
View directory record Official record
Conditions
Pain, Intractable Pain, Chronic Pain
Interventions
Precision for Spinal Cord Stimulation
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Napa, California
Source: ClinicalTrials.gov public record
Updated Dec 17, 2020 · Synced Oct 9, 2026, 5:24 PM EDT
Completed Phase 3 Interventional

Safety and Efficacy of the Buprenorphine Transdermal Delivery System in Subjects With Osteoarthritis Pain.

NCT00314652
View directory record Official record
Conditions
Osteoarthritis
Interventions
Buprenorphine transdermal delivery system
Drug
Lead sponsor
Purdue Pharma LP
Industry
Eligibility
18 Years and older
Enrollment
260 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999
U.S. locations
22
States / cities
Phoenix, Arizona • Tucson, Arizona • San Diego, California + 16 more
Source: ClinicalTrials.gov public record
Updated May 3, 2006 · Synced Oct 9, 2026, 5:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Integrative Psychosocial Group Treatment

NCT03648177
View directory record Official record
Conditions
Chronic Pain, Opioid Misuse
Interventions
IPGT, Treatment as Usual
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 64 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 6, 2019 · Synced Oct 9, 2026, 5:24 PM EDT