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Showing 1–24 of 72 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Chronic Physical Health Conditions Clear all
Completed Not applicable Interventional

A Computer-Based Intervention for Medically Unexplained Physical Symptoms

NCT00468013
View directory record Official record
Conditions
Fibromyalgia, Irritable Bowel Syndrome, Chronic Fatigue Syndrome
Interventions
Resilience Building Exercises, Journaling
Behavioral
Lead sponsor
University of Medicine and Dentistry of New Jersey
Other
Eligibility
18 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated Feb 8, 2015 · Synced Sep 8, 2026, 11:50 AM EDT
Completed Not applicable Interventional

Vermont Diabetes Information System

NCT00109369
View directory record Official record
Conditions
Diabetes Mellitus
Interventions
Information and decision support for providers and patients
Other
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years and older
Enrollment
7,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2007
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Jan 31, 2011 · Synced Sep 8, 2026, 11:50 AM EDT
Not listed Not applicable Interventional

Brain Injury Therapy of Exercise and Enriched Environment

NCT03256643
View directory record Official record
Conditions
Brain Injuries
Interventions
Exercise, Delayed Exercise, Exercise and enrichment
Behavioral
Lead sponsor
Wayne State University
Other
Eligibility
18 Years to 75 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Taylor, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 25, 2020 · Synced Sep 8, 2026, 11:50 AM EDT
Completed Not applicable Interventional

Goal Oriented Activity for Latinos With Spine Pain

NCT05005416
View directory record Official record
Conditions
Low Back Pain, Neck Pain, Chronic Pain, Chronic Low-back Pain
Interventions
GOALS Intervention, Usual Care Physical Therapy
Behavioral
Lead sponsor
San Diego State University
Other
Eligibility
18 Years to 66 Years
Enrollment
138 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
2
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Feb 9, 2025 · Synced Sep 8, 2026, 11:50 AM EDT
Active, not recruiting Not applicable Interventional

The Development of an Integrated Physical Activity and Mental Health Intervention for Veterans With COPD, Emotion Distress, and Low Physical Activity

NCT04953806
View directory record Official record
Conditions
COPD, Depression, Anxiety
Interventions
Step-CBT
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
40 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Sep 8, 2026, 11:50 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Open-label, Post-marketing, Prospective Study to Assess Impact of COVID-19 on Cognitive Function in Patients

NCT04950673
View directory record Official record
Conditions
Cognitive Decline, Cognitive Dysfunction, Brain Health, Post CoV-2 Syndrome, COVID Long-Haul
Interventions
Cognivue
Device
Lead sponsor
Cognivue, Inc.
Industry
Eligibility
18 Years to 95 Years
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
4
States / cities
Irvine, California • Visalia, California • Boca Raton, Florida + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 21, 2022 · Synced Sep 8, 2026, 11:50 AM EDT
Completed Not applicable Interventional Results available

Development of STEPPT

NCT06835439
View directory record Official record
Conditions
Pain, Back Pain, Low Back Pain, Chronic Pain, Neck Pain
Interventions
STEPPT Pilot, Standard Care (Control)
Behavioral
Lead sponsor
San Diego State University
Other
Eligibility
18 Years and older
Enrollment
144 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated May 10, 2026 · Synced Sep 8, 2026, 11:50 AM EDT
Completed Not applicable Interventional

A Trial of a Positive Psychology Intervention for Older Adults (RESET)

NCT05451589
View directory record Official record
Conditions
Depressive Symptoms, Anxiety, Chronic Pain, Fatigue, Loneliness, Stress, Psychological
Interventions
RESET, Wellness Check Control
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
50 Years and older
Enrollment
457 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Sep 8, 2026, 11:50 AM EDT
Completed Not applicable Interventional

Nature and Health: How Does Lifestyle and Environment Affect Health and Wellness

NCT06001697
View directory record Official record
Conditions
Chronic Disease, Risk Reduction, Mental Health Wellness 1, Physical Inactivity, Sleep, Depression, Anxiety
Interventions
Park prescription, Regular health advice
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
13 Years to 65 Years
Enrollment
134 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Monroeville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 5, 2025 · Synced Sep 8, 2026, 11:50 AM EDT
Completed Not applicable Interventional Results available

The Effect of Physical Activity Promotion on Short and Long-term Outcomes in COPD

NCT02099799
View directory record Official record
Conditions
COPD, Emphysema, Chronic Bronchitis
Interventions
Pedometer and Website
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
40 Years and older
Enrollment
153 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
2
States / cities
Birmingham, Alabama • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 4, 2021 · Synced Sep 8, 2026, 11:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Denver Garden Environment and Microbiome Study Disease

NCT03089151
View directory record Official record
Conditions
Diet Modification, Physical Activity, Weight Gain, Chronic Disease, Lifestyle, Sedentary, Health Behavior
Interventions
Community Garden Intervention
Behavioral
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated May 6, 2021 · Synced Sep 8, 2026, 11:50 AM EDT
Completed Not applicable Interventional Results available

Brief COVID-19 Intervention for People With Serious Mental Illness and Co-Morbid Medical Conditions

NCT05467982
View directory record Official record
Conditions
Mental Illness, Chronic Disease
Interventions
Integrated Illness Management and Recovery, Chronic Disease Self-Management Program
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
164 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
2
States / cities
Louisville, Kentucky • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 11, 2024 · Synced Sep 8, 2026, 11:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Self-Management in Parents of Technology-Dependent Children

NCT04105244
View directory record Official record
Conditions
Caregivers, Parents, Self-Management, Chronic Illnesses, Multiple
Interventions
Resourcefulness Training©
Behavioral
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years and older
Enrollment
202 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 5, 2024 · Synced Sep 8, 2026, 11:50 AM EDT
Active, not recruiting Not applicable Interventional

SMART Stepped Care Management for Low Back Pain in the Military Health System

NCT04172038
View directory record Official record
Conditions
Low Back Pain, Chronic Pain, Military Personnel, Veterans
Interventions
Physical Therapy, Move 2 Health (M2H), MORE Mindfulness
Behavioral
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
18 Years to 65 Years
Enrollment
850 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
4
States / cities
Schofield Barracks, Hawaii • San Antonio, Texas • Tacoma, Washington
Source: ClinicalTrials.gov public record
Updated Jan 13, 2025 · Synced Sep 8, 2026, 11:50 AM EDT
Completed Not applicable Interventional

MANAGE AT WORK: Addressing the Challenge of Chronic Physical Health Conditions in the Workplace

NCT01978392
View directory record Official record
Conditions
Chronic Physical Health Conditions
Interventions
Self-management group workshops
Behavioral
Lead sponsor
Liberty Mutual Research Institute for Safety
Industry
Eligibility
18 Years and older
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
4
States / cities
Worcester, Massachusetts • Hanover, New Hampshire • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jun 1, 2017 · Synced Sep 8, 2026, 11:50 AM EDT
Terminated Not applicable Interventional

Community Health Worker Intervention to Improve Post-Hospital Outcomes

NCT04028609
View directory record Official record
Conditions
Chronic Disease (Physical), Mental Disorder
Interventions
Healthy at Home, Services as Usual
Behavioral · Other
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
21 Years to 60 Years
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 27, 2023 · Synced Sep 8, 2026, 11:50 AM EDT
Completed Not applicable Interventional Results available

A Mobile Intervention to Reduce Pain and Improve Health (MORPH)

NCT03377634
View directory record Official record
Conditions
Chronic Pain, Obesity, Sedentary Lifestyle
Interventions
MORPH
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
65 Years to 79 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 21, 2021 · Synced Sep 8, 2026, 11:50 AM EDT
Completed Not applicable Interventional

Physical Activity and Social Engagement for Persons With Disabilities in an Underserved Community

NCT05247242
View directory record Official record
Conditions
Disability Physical, Chronic Conditions, Multiple, Aging
Interventions
Lakeshore Online Fitness (Online), Get Active with Virtual Reality (VR)
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Tarrant, Alabama
Source: ClinicalTrials.gov public record
Updated Jan 19, 2025 · Synced Sep 8, 2026, 11:50 AM EDT
Completed Not applicable Interventional

Assessing Novel Methods of Improving Patient Education of Nutrition

NCT00394576
View directory record Official record
Conditions
Chronic Kidney Disease
Interventions
Internet-based nutrition module along with usual care, usual care
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 90 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 5, 2019 · Synced Sep 8, 2026, 11:50 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Health Electronic Assessment of Risks and Trends Using Biometric Equipment and Technology

NCT06753045
View directory record Official record
Conditions
Heart Diseases
Interventions
Smartwatch
Other
Lead sponsor
Tulane University
Other
Eligibility
18 Years to 120 Years
Enrollment
10,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
3
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Mar 4, 2026 · Synced Sep 8, 2026, 11:50 AM EDT
Active, not recruiting Not applicable Interventional

Positive Minds Strong Joints for Knee Osteoarthritis

NCT06493903
View directory record Official record
Conditions
Osteoarthritis, Knee
Interventions
Positive Minds, Strong Joints
Behavioral
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
50 Years and older
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Sep 8, 2026, 11:50 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Energy Balance Interventions in Increasing Physical Activity in Breast Cancer Gene Positive Patients, Lynch Syndrome-Positive Patients, CLL Survivors or High-Risk Family Members

NCT02194387
View directory record Official record
Conditions
Body Mass Index 25 or Greater, BRCA1 Gene Mutation, BRCA2 Gene Mutation, Breast Carcinoma, Cancer Survivor, Chronic Lymphocytic Leukemia, Fatigue, Health Status Unknown, Lynch Syndrome, Ovarian Carcinoma, Overweight
Interventions
Dietary Intervention, Internet-Based Intervention, Laboratory Biomarker Analysis, Questionnaire Administration, Telephone-Based Intervention
Dietary Supplement · Other · Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
337 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 8, 2026 · Synced Sep 8, 2026, 11:50 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Assessing Symptom and Mood Dynamics in Pain Using the Smartphone Application SOMA

NCT05754190
View directory record Official record
Conditions
Chronic Pain, Acute Pain, Post Operative Pain, Fibromyalgia, Primary, Fibromyalgia, Secondary, Fibromyalgia, Irritable Bowel Syndrome, Chronic Headache Disorder, Chronic Migraine, Chronic Pelvic Pain Syndrome, Temporomandibular Joint Disorders, Endometriosis-related Pain, Arthritis, Chronic Low-back Pain, Failed Back Surgery Syndrome, Post Herpetic Neuralgia, Neuropathic Pain, Painful Diabetic Neuropathy, Painful Bladder Syndrome, Trauma-related Wound, Trauma, Multiple, Chronic Pain Syndrome, Chronic Shoulder Pain
Interventions
SOMA pain manager smartphone application
Device
Lead sponsor
Brown University
Other
Eligibility
18 Years and older
Enrollment
800 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Sep 18, 2025 · Synced Sep 8, 2026, 11:50 AM EDT
Active, not recruiting Not applicable Interventional

REACH (Restore Energy, Activity Can Help) Lupus Study

NCT06479213
View directory record Official record
Conditions
Systemic Lupus Erythematosus, Fatigue
Interventions
REACH Peer Coaching Program, REACH Mobile Health Application
Behavioral
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 19, 2025 · Synced Sep 8, 2026, 11:50 AM EDT