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ClinicalTrials.gov public records Last synced Oct 20, 2026, 6:46 AM EDT

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Showing 145–168 of 338 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Chronic Stroke Clear all
Completed Not applicable Interventional Results available

Portable EMG-triggered Hand Robot for Individuals After Stroke

NCT02364700
View directory record Official record
Conditions
Stroke
Interventions
Hand of Hope (HOH)
Device
Lead sponsor
Rehab-Robotics Company Limited
Industry
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 12, 2017 · Synced Oct 20, 2026, 6:46 AM EDT
Completed Not applicable Interventional

Can Patients With Chronic Stroke Regain Living Independence by Daily Energizing With Biophoton Generators

NCT06049849
View directory record Official record
Conditions
Chronic Stroke
Interventions
Biophoton Energizing Brain and Whole Body
Device
Lead sponsor
First Institute of All Medicines
Other
Eligibility
18 Years to 80 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Butler, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 8, 2025 · Synced Oct 20, 2026, 6:46 AM EDT
Completed Not applicable Interventional Results available

Closed-loop Deep Brain Stimulation to Treat Refractory Neuropathic Pain

NCT03029884
View directory record Official record
Conditions
Chronic Pain, Post Stroke Pain, Phantom Limb Pain, Spinal Cord Injuries
Interventions
Open-Loop DBS, Sham Stimulation, Closed-Loop DBS
Device
Lead sponsor
Prasad Shirvalkar, MD, PhD
Other
Eligibility
21 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2026
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 4, 2026 · Synced Oct 20, 2026, 6:46 AM EDT
Recruiting Phase 2 Interventional

Novel Wrist Sensor System to Promote Hemiparetic Arm Use in Home Daily Life of Chronic Stroke Survivors

NCT05626894
View directory record Official record
Conditions
Stroke, Stroke Sequelae, Hemiparesis;Poststroke/CVA
Interventions
StrokeWear Motor and Behavioral Intervention, Usual Care
Combination Product · Other
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 85 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 28, 2025 · Synced Oct 20, 2026, 6:46 AM EDT
Completed Not applicable Interventional

Pilot Study: A Novel Method of Non-Invasive Brain Stimulation (kTMP) to Enhance Motor Function in Chronic Stroke Patients

NCT06317194
View directory record Official record
Conditions
Stroke
Interventions
kTMP
Device
Lead sponsor
Magnetic Tides
Industry
Eligibility
18 Years to 80 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Oct 20, 2026, 6:46 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

ACT Group for Family Caregivers of Stroke Survivors

NCT07528261
View directory record Official record
Conditions
Caregiver Stress, Caregiver Stress Syndrome, Caregiver Burnout, Caregiver Distress, Caregiver Exhaustion, Caregiver Health Related QOL, Caregiver Burden for Those Who Care for Adults With Impaired Functional Status, Caregiver Quality of Life, Caregiver Burden, Caregiver Mental Health, Caregiver Resilience and Stress, Caregiver Sense of Control Over Life, Caregiver Awareness, Caregiver Stress in Chronic Mental Illness
Interventions
Group-based ACT Intervention
Behavioral
Lead sponsor
The Wright Institute
Other
Eligibility
40 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Alameda, California
Source: ClinicalTrials.gov public record
Updated May 1, 2026 · Synced Oct 20, 2026, 6:46 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Neural Operant Conditioning

NCT06113965
View directory record Official record
Conditions
Stroke, Chronic Stroke, Gait, Hemiplegic, Gait, Spastic, Walking, Difficulty
Interventions
Peripheral Nerve Stimulation
Device
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 10, 2025 · Synced Oct 20, 2026, 6:46 AM EDT
Completed Not applicable Interventional

Constraint-induced Movement Therapy to Improve Gait and Mobility of People With Chronic Stroke

NCT03114046
View directory record Official record
Conditions
Rehabilitation, Recovery of Function, Stroke, Lower Extremity Paresis
Interventions
Lower extremity Constraint-induced movement therapy(LE-CIMT)
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jan 23, 2023 · Synced Oct 20, 2026, 6:46 AM EDT
Completed Not applicable Interventional Results available

Effects of Transcranial Direct Current Stimulation (tDCS) on Language

NCT04166513
View directory record Official record
Conditions
Stroke, Aphasia
Interventions
Targeted Transcranial Direct Current Stimulation, Active Control Transcranial Direct Current Stimulation, Phonologic-Focused Speech Therapy, Semantic-Focused Speech Therapy
Device · Behavioral
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years to 85 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 3, 2025 · Synced Oct 20, 2026, 6:46 AM EDT
Completed No phase listed Observational

CADASIL Disease Discovery

NCT02821780
View directory record Official record
Conditions
Germline Mutation in the NOTCH 3 Gene, Cardiovascular Disease, Arterial Stiffness, Pathogenesis of CADASIL, Clinical Phenotype of CADASIL
Interventions
Not listed
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
18 Years to 100 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
2
States / cities
Bethesda, Maryland • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Oct 20, 2026, 6:46 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Mapping Corticoreticulospinal Motor Control in Chronic Hemiparetic Stroke

NCT06598150
View directory record Official record
Conditions
Stroke, Hemiparesis
Interventions
Shoulder Abduction
Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 1, 2025 · Synced Oct 20, 2026, 6:46 AM EDT
Recruiting Not applicable Interventional

Exoskeleton Research: Myoelectric Orthosis for Rehab of Severe Chronic Arm Motor Deficits

NCT05296408
View directory record Official record
Conditions
Chronic Stroke
Interventions
motor learning based therapy, MyoPro, Home Exercise Program
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 89 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 21, 2026 · Synced Oct 20, 2026, 6:46 AM EDT
Completed Phase 2 Interventional

Volitional Swallowing in Stroke Patients With Chronic Dysphagia

NCT00306501
View directory record Official record
Conditions
Stroke, Dysphagia
Interventions
Swallowing Training
Procedure
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years to 75 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Oct 20, 2026, 6:46 AM EDT
Completed No phase listed Observational

Real World Testing of a Brain-Computer Interface

NCT04026581
View directory record Official record
Conditions
Amyotrophic Lateral Sclerosis, Brain Stem Stroke, Cerebral Palsy, Traumatic Brain Injury, Speech Disorders
Interventions
Speech generating device (SGD) evaluation including BCI access, Training and treatment
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
14 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
2
States / cities
Carnegie, Pennsylvania • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 6, 2023 · Synced Oct 20, 2026, 6:46 AM EDT
Completed No phase listed Observational

Exploring Folk Health Practices in Latinos With Chronic Medical Conditions

NCT00224237
View directory record Official record
Conditions
Diabetes, Hypertension, Asthma, Heart Disease, Stroke, Arthritis
Interventions
Not listed
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 100 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 23, 2017 · Synced Oct 20, 2026, 6:46 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Explore the Effects of Cortical Priming on Visuomotor Stepping Learning in Persons With Chronic Stroke

NCT06681207
View directory record Official record
Conditions
Stroke
Interventions
anodal transcranial direct current stimulation (a-tDCS)
Combination Product
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
21 Years to 90 Years
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 14, 2026 · Synced Oct 20, 2026, 6:46 AM EDT
Completed Not applicable Interventional Results available

Primed vs. Unprimed rTMS in Chronic Stroke

NCT01757821
View directory record Official record
Conditions
Stroke
Interventions
real 6-Hz primed low-frequency rTMS, Sham 6-Hz Primed low-frequency rTMS, real 1-Hz rTMS only
Device
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 2, 2017 · Synced Oct 20, 2026, 6:46 AM EDT
Terminated Not applicable Interventional

Hand Rehabilitation Study for Stroke Patients

NCT03148106
View directory record Official record
Conditions
Upper Extremity Paresis, Disability Physical, Chronic Stroke, Motor Disorders
Interventions
Somatosensory Electrical Stimulation
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 80 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2025
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Oct 20, 2026, 6:46 AM EDT
Completed Phase 3 Interventional

Perinatal Arterial Stroke: A Multi-site RCT of Intensive Infant Rehabilitation (I-ACQUIRE)

NCT03910075
View directory record Official record
Conditions
Perinatal Stroke, Hemiparesis
Interventions
I-ACQUIRE - High Dosage, I-ACQUIRE - Moderate Dosage, Usual & Customary Treatment (U&CT)
Behavioral
Lead sponsor
Virginia Polytechnic Institute and State University
Other
Eligibility
8 Months to 36 Months
Enrollment
216 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
15
States / cities
La Jolla, California • New Haven, Connecticut • Chicago, Illinois + 12 more
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Oct 20, 2026, 6:46 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Imaging Laterality in Chronic Stroke Patients

NCT03584425
View directory record Official record
Conditions
Stroke, Motor Cortex; Lesion
Interventions
Rasch modified version of the Fugl-Meyer Motor assessment, Anatomical image acquisition, Functional MRI task and acquisition
Diagnostic Test
Lead sponsor
Medical University of South Carolina
Other
Eligibility
21 Years to 80 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 23, 2019 · Synced Oct 20, 2026, 6:46 AM EDT
Completed Not applicable Interventional Results available

Ankle Robot to Reduce Foot Drop in Stroke

NCT02483676
View directory record Official record
Conditions
Stroke, Foot Drop
Interventions
Treadmill plus anklebot, Treadmill only
Device · Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 20, 2020 · Synced Oct 20, 2026, 6:46 AM EDT
Not listed Not applicable Interventional

Feasibility of a Stroke Specific Self-management Program

NCT03993574
View directory record Official record
Conditions
Stroke, Chronic Conditions
Interventions
Self- management program, Standard care
Other
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 8, 2021 · Synced Oct 20, 2026, 6:46 AM EDT
Recruiting Not applicable Interventional

Promoting Recovery After Brain Injury Using Focused Ultrasound

NCT07277309
View directory record Official record
Conditions
Consciousness Disorders, Disorders of Consciousness Due to Severe Brain Injury
Interventions
Low-intensity focused ultrasound
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 79 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
2
States / cities
Boston, Massachusetts • Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 15, 2026 · Synced Oct 20, 2026, 6:46 AM EDT
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

Chronic Transcutaneous Stimulation to Promote Motor Function and Recovery in Individuals With Paralysis or Paresis

NCT04755699
View directory record Official record
Conditions
Healthy Volunteers, Spinal Cord Injury, Stroke, Paralysis, Paresis, Neurological Injury
Interventions
Transcutaneous Electrical Stimulation
Device
Lead sponsor
Northwell Health
Other
Eligibility
18 Years to 75 Years
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2028
U.S. locations
1
States / cities
Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Mar 11, 2026 · Synced Oct 20, 2026, 6:46 AM EDT