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ClinicalTrials.gov public records Last synced Oct 4, 2026, 9:58 PM EDT

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Showing 49–71 of 71 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Chronic Venous Insufficiency Clear all
Completed Not applicable Interventional

Feasibility Study of Cryotherapy for Chronic Venous Disorders

NCT00617825
View directory record Official record
Conditions
Venous Insufficiency
Interventions
cyrotherapy as a cool gel wrap
Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
45 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jun 15, 2018 · Synced Oct 4, 2026, 9:58 PM EDT
Completed Not applicable Interventional

Prefistula Forearm Exercise in Pts Requiring Chronic HD Therapy

NCT03988270
View directory record Official record
Conditions
Arterio-venous Fistula, Kidney Failure, Hemodialysis Access Failure
Interventions
Exercise
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 10, 2022 · Synced Oct 4, 2026, 9:58 PM EDT
Terminated Phase 4 Interventional Results available

Radiofrequency Ablation vs. Laser Ablation of the Incompetent Small Saphenous Vein

NCT02248740
View directory record Official record
Conditions
Chronic Venous Insufficiency
Interventions
Ablation of the incompetent small saphenous vein
Procedure
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2017
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 7, 2019 · Synced Oct 4, 2026, 9:58 PM EDT
Not listed Phase 3 Interventional

A Multi-Centered, Two-Arm, Randomized Study Comparing the Effects of AAT-023 (Zuragen) Solution, and Heparin on the Incidence of Catheter Related Blood Stream Infections in Tunneled Chronic Central Venous Catheters for Dialysis

NCT00628680
View directory record Official record
Conditions
End Stage Renal Disease
Interventions
AAT-023 solution (Zuragen), Heparin
Device · Drug
Lead sponsor
Ash Access Technology
Industry
Eligibility
18 Years and older
Enrollment
415 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2006
U.S. locations
22
States / cities
Bakersfield, California • Lynwood, California • Middlebury, Connecticut + 17 more
Source: ClinicalTrials.gov public record
Updated Mar 5, 2008 · Synced Oct 4, 2026, 9:58 PM EDT
Completed Not applicable Interventional Results available

Venous Stent for the Iliofemoral Vein Investigational Clinical Trial Using the DUO Venous Stent System

NCT04580160
View directory record Official record
Conditions
May-Thurner Syndrome, Deep Vein Thrombosis, Chronic Venous Insufficiency
Interventions
Duo Venous Stent System
Device
Lead sponsor
Vesper Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
162 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
28
States / cities
Orange, California • Palo Alto, California • Darien, Connecticut + 24 more
Source: ClinicalTrials.gov public record
Updated May 15, 2025 · Synced Oct 4, 2026, 9:58 PM EDT
Completed Not applicable Interventional Results available

Clinical Study of the BARD® COVERA™ Arteriovenous (AV) Stent Graft in AV Graft Patients (AVeVA)

NCT02790606
View directory record Official record
Conditions
Stenosis, Restenosis
Interventions
Covera(TM) Vascular Covered Stent
Device
Lead sponsor
C. R. Bard
Industry
Eligibility
21 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
16
States / cities
Phoenix, Arizona • Tempe, Arizona • Tucson, Arizona + 12 more
Source: ClinicalTrials.gov public record
Updated Apr 14, 2020 · Synced Oct 4, 2026, 9:58 PM EDT
Completed Not applicable Interventional

A Clinical Study to Evaluate the Effectiveness of a Novel Portable Non-Pneumatic Active Compression Device vs. an Advanced Pneumatic Compression Device for Treating Lower Extremity Lymphedema

NCT05507346
View directory record Official record
Conditions
Lymphedema, Lymphedema of Leg, Chronic Venous Insufficiency, Venous Insufficiency, Lymphedema, Lower Limb
Interventions
Cross over Device (PCD or Dayspring - alternate to first group)
Device
Lead sponsor
Koya Medical, Inc.
Industry
Eligibility
18 Years to 100 Years
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Oakland, California
Source: ClinicalTrials.gov public record
Updated Dec 12, 2025 · Synced Oct 4, 2026, 9:58 PM EDT
Completed Phase 2 Interventional Results available

Cooling Leg and Foot Ulcer Skin Post Healing to Prevent Ulcer Recurrence

NCT02626156
View directory record Official record
Conditions
Venous Hypertension Ulcers, Venous Stasis Ulcer, Venous Ulcer, Venous Insufficiency, Leg Ulcer, Foot Ulcer, Varicose Ulcer, Diabetic Foot
Interventions
Cooling gel pack, Cooling cotton pack
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
50 Years and older
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
2
States / cities
Charleston, South Carolina • Spartanburg, South Carolina
Source: ClinicalTrials.gov public record
Updated Jun 30, 2021 · Synced Oct 4, 2026, 9:58 PM EDT
Completed Phase 4 Interventional Results available

Radiofrequency Ablation vs Laser Ablation of the Incompetent Greater Saphenous Vein

NCT02236338
View directory record Official record
Conditions
Chronic Venous Insufficiency
Interventions
Ablation of the Incompetent Greater Saphenous Vein, ClosureFAST radiofrequency catheter, EVLT 980nm diode laser system
Procedure · Device
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2016
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated May 14, 2018 · Synced Oct 4, 2026, 9:58 PM EDT
Completed Phase 4 Interventional Results available

Treatment of Chronic Deep Vein Thrombosis (DVT) and Post-Thrombotic Syndrome (PTS) With the EkoSonic® Endovascular System

NCT02159521
View directory record Official record
Conditions
Deep Vein Thrombosis, Post-thrombotic Syndrome
Interventions
EkoSonic® Endovascular System, Alteplase
Device · Biological
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years to 75 Years
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
22
States / cities
Los Angeles, California • Aurora, Colorado • Darien, Connecticut + 18 more
Source: ClinicalTrials.gov public record
Updated Jul 19, 2021 · Synced Oct 4, 2026, 9:58 PM EDT
Completed No phase listed Observational

Head Circumference Growth in Children With Ehlers-Danlos Syndrome Who Develop Dysautonomia Later in Life

NCT01367977
View directory record Official record
Conditions
Ehlers Danlos Syndrome, External Hydrocephalus, Dysautonomia, Postural Orthostatic Tachycardia Syndrome, Venous Insufficiency
Interventions
Not listed
Lead sponsor
Genetic Disease Investigators
Other
Eligibility
5 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Colleyville, Texas
Source: ClinicalTrials.gov public record
Updated Feb 14, 2024 · Synced Oct 4, 2026, 9:58 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Hypoxemia in Maintenance Hemodialysis Patients

NCT03045796
View directory record Official record
Conditions
Oxygen Saturation and the Relationship to Other Cardiac Variables, Maintenance Hemodialysis, Kidney Failure, Chronic
Interventions
Oxygen Saturation measured by WristOx
Device
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated May 11, 2017 · Synced Oct 4, 2026, 9:58 PM EDT
Completed Not applicable Interventional Results available

Venclose RF Ablation System for the Treatment of IPVs

NCT04386785
View directory record Official record
Conditions
Chronic Venous Insufficiency
Interventions
Radiofrequency (RF) Thermal Ablation of Incompetent Perforator Veins
Device
Lead sponsor
Venclose, Inc.
Industry
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Tyler, Texas
Source: ClinicalTrials.gov public record
Updated May 27, 2022 · Synced Oct 4, 2026, 9:58 PM EDT
Completed Not applicable Interventional Results available

VasQ External Support for Arteriovenous Fistula

NCT03242343
View directory record Official record
Conditions
Arterio-Venous Fistula, ESRD, Steal Syndrome, Aneurysm, Renal Failure, Renal Disease, Diabetes Mellitus, Kidney Failure
Interventions
VasQ
Device
Lead sponsor
Laminate Medical Technologies
Industry
Eligibility
18 Years to 80 Years
Enrollment
144 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
15
States / cities
Birmingham, Alabama • Phoenix, Arizona • Peoria, Illinois + 11 more
Source: ClinicalTrials.gov public record
Updated May 27, 2026 · Synced Oct 4, 2026, 9:58 PM EDT
Withdrawn Phase 3 Interventional

Clinical Effectiveness of Topical Autologous Platelet Gel for the Treatment of Venous Ulcers

NCT00273234
View directory record Official record
Conditions
Venous Ulcer
Interventions
Autologous Platelet Gel (APG)
Procedure
Lead sponsor
National Healing Corporation
Industry
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006
U.S. locations
6
States / cities
St. Petersburg, Florida • Titusville, Florida • Newburyport, Massachusetts + 3 more
Source: ClinicalTrials.gov public record
Updated Mar 6, 2007 · Synced Oct 4, 2026, 9:58 PM EDT
Active, not recruiting Not applicable Interventional

Chronic Venous Thrombosis: Relief With Adjunctive Catheter-Directed Therapy (The C-TRACT Trial)

NCT03250247
View directory record Official record
Conditions
Deep Vein Thrombosis, Venous Stasis, Venous Insufficiency, Venous Leg Ulcer, Venous Reflux, Post Thrombotic Syndrome
Interventions
Stents
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
225 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
29
States / cities
Orange, California • San Francisco, California • New Haven, Connecticut + 23 more
Source: ClinicalTrials.gov public record
Updated Jan 28, 2026 · Synced Oct 4, 2026, 9:58 PM EDT
Recruiting Not applicable Interventional

Pedal Pump Clinical Trial on Edema V2

NCT07809516
View directory record Official record
Conditions
Lower Extremity Edema, Lower Extremity Edema Chronic, CHF - Congestive Heart Failure, CHF Exacerbation, Chronic Venous Insufficiency, CVI
Interventions
Pedal Pump, Pedal Pump Sham
Device
Lead sponsor
Hillcrest
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Oct 4, 2026, 9:58 PM EDT
Completed Phase 2Phase 3 Interventional Results available

Safety and Efficacy Study of the Venous Window Needle Guide to Access Arteriovenous (AV)Fistulae

NCT01471041
View directory record Official record
Conditions
End Stage Renal Disease, AV Fistula, Kidney Failure
Interventions
Venous Window Needle Guide
Device
Lead sponsor
Vital Access Corp.
Industry
Eligibility
18 Years and older
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
2
States / cities
Fresno, California • Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jun 3, 2016 · Synced Oct 4, 2026, 9:58 PM EDT
Completed Not applicable Interventional Results available

Evaluation of a Dual Action Pneumatic Compression System: Tolerance and Comfort in Patients With Venous Leg Ulcers (VLUs)

NCT02395302
View directory record Official record
Conditions
Venous Leg Ulcer, Chronic Venous Insufficiency, Venous Stasis Ulcer, Venous Ulcer, Venous Insufficiency
Interventions
Dual Action Pneumatic Compression
Device
Lead sponsor
Tactile Medical
Industry
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
6
States / cities
San Francisco, California • Miami, Florida • Boston, Massachusetts + 2 more
Source: ClinicalTrials.gov public record
Updated Mar 27, 2017 · Synced Oct 4, 2026, 9:58 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Study To Evaluate Treating Chronic Cerebrospinal Venous Insufficiency (CCSVI) in Multiple Sclerosis Patients

NCT01089686
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Venoplasty, Sham procedure (non-treatment)
Procedure
Lead sponsor
Manish Mehta, MD
Other
Eligibility
18 Years to 65 Years
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Albany, New York
Source: ClinicalTrials.gov public record
Updated Mar 7, 2012 · Synced Oct 4, 2026, 9:58 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

A Non-randomized, Open-Label Study to Evaluate the Safety and Effectiveness of Insight® Pro Device for Evaluating Lymphatic and Venous Disorders (VOLGA)

NCT05628688
View directory record Official record
Conditions
Lymphedema, Chronic Venous Insufficiency, Edema, Venous Insufficiency of Leg
Interventions
Insight Pro Device for Diagnosis
Diagnostic Test
Lead sponsor
Koya Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Oakland, California
Source: ClinicalTrials.gov public record
Updated Dec 12, 2025 · Synced Oct 4, 2026, 9:58 PM EDT
Completed Phase 3 Interventional Results available

Study Assessing Safety & Effectiveness of a Catheter Lock Solution in Dialysis Patients to Prevent Bloodstream Infection

NCT02651428
View directory record Official record
Conditions
Kidney Failure, Chronic, Catheter-Related Infections
Interventions
Neutrolin, Heparin
Drug
Lead sponsor
CorMedix Therapeutics
Industry
Eligibility
18 Years and older
Enrollment
806 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
5
States / cities
Riverside, California • San Dimas, California • Miami Gardens, Florida + 2 more
Source: ClinicalTrials.gov public record
Updated Feb 25, 2025 · Synced Oct 4, 2026, 9:58 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Non-Invasive Management of Chronic Venous Insufficiency

NCT00950378
View directory record Official record
Conditions
Venous Insufficiency
Interventions
Not listed
Lead sponsor
University of Utah
Other
Eligibility
40 Years to 60 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated May 29, 2013 · Synced Oct 4, 2026, 9:58 PM EDT