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ClinicalTrials.gov public records Last synced Oct 19, 2026, 10:57 AM EDT

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Showing 1–24 of 408 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Cicatrix Clear all
Terminated Phase 3 Interventional

Seprafilm® for Prevention of Adhesions at Repeat Cesarean

NCT00697606
View directory record Official record
Conditions
Adhesion Formation After Primary Cesarean Delivery
Interventions
Seprafilm®, Control
Device · Other
Lead sponsor
Abington Memorial Hospital
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
450 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Abington, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 30, 2015 · Synced Oct 19, 2026, 10:57 AM EDT
Completed Phase 2 Interventional

A Study for Safety and Efficacy Evaluation of Various Doses of STP705 in Reducing Keloid Recurrence

NCT04844840
View directory record Official record
Conditions
Keloid
Interventions
STP705, Placebo
Drug · Other
Lead sponsor
Sirnaomics
Industry
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
3
States / cities
Scottsdale, Arizona • Aventura, Florida • Hackensack, New Jersey
Source: ClinicalTrials.gov public record
Updated Mar 19, 2024 · Synced Oct 19, 2026, 10:57 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Vollure for the Correction of Atrophic Facial Scarring

NCT04519515
View directory record Official record
Conditions
Atrophic Scar
Interventions
Allergan Vollure
Device
Lead sponsor
Siperstein Dermatology
Other
Eligibility
22 Years and older
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Boynton Beach, Florida
Source: ClinicalTrials.gov public record
Updated Feb 15, 2022 · Synced Oct 19, 2026, 10:57 AM EDT
Completed Not applicable Interventional

Clinical Trial To Study The Anti-scarring Effect Of Cicatricell

NCT03020420
View directory record Official record
Conditions
Surgical Incisions
Interventions
Cicatricell Cream
Other
Lead sponsor
University of Toledo Health Science Campus
Other
Eligibility
18 Years to 60 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Toledo, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 5, 2024 · Synced Oct 19, 2026, 10:57 AM EDT
Completed Not applicable Interventional

Serial Platelet-Rich Plasma Injections for Vocal Fold Atrophy, Scar, and/or Sulcus Vocalis

NCT03749863
View directory record Official record
Conditions
Presbylarynx, Atrophy; Larynx, Dysphonia, Vocal Cord Atrophy, Presbylarynges, Vocal Fold Scar, Sulcus Vocalis of Vocal Cord
Interventions
Serial PRP injections
Procedure
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 10, 2023 · Synced Oct 19, 2026, 10:57 AM EDT
Not listed Phase 2 Interventional

Pediatric Multicenter Study of REPEL-CV

NCT00116233
View directory record Official record
Conditions
Adhesions
Interventions
REPEL-CV
Device
Lead sponsor
SyntheMed
Industry
Eligibility
1 Day to 1 Year
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
1
States / cities
Little Silver, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 28, 2005 · Synced Oct 19, 2026, 10:57 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Laser Treatment for Fresh Surgical Scars and Mature Scars

NCT01030198
View directory record Official record
Conditions
New Surgical Scars, Scars
Interventions
RevLite (Laser Treatment)
Device
Lead sponsor
Cynosure, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010
U.S. locations
1
States / cities
Boca Raton, Florida
Source: ClinicalTrials.gov public record
Updated Dec 17, 2020 · Synced Oct 19, 2026, 10:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Laser Resurfacing Versus Dermabrasion for Scar Revision

NCT01176448
View directory record Official record
Conditions
Cicatrix, Dermabrasion, Coagulation, Laser
Interventions
Fractionated laser, Dermabrasion
Device
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010
U.S. locations
1
States / cities
Edina, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 1, 2019 · Synced Oct 19, 2026, 10:57 AM EDT
Completed Phase 2 Interventional Results available

Dual JAK1/TYK2 Inhibitor for Cicatricial Alopecia

NCT05076006
View directory record Official record
Conditions
Cicatricial Alopecia
Interventions
PF-06700841, Placebo
Drug
Lead sponsor
Emma Guttman
Other
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 19, 2026 · Synced Oct 19, 2026, 10:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Medipore Tape Study

NCT02676115
View directory record Official record
Conditions
Scarring
Interventions
Standard Post Operative Skin Care, Medipore Tape
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
15 Years to 95 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 8, 2016 · Synced Oct 19, 2026, 10:57 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Clinical Study to Evaluate the Safety and Effectiveness of the Treatment With Tixel C on Acne Scars

NCT04269317
View directory record Official record
Conditions
Scars
Interventions
Tixel C
Device
Lead sponsor
Novoxel Ltd.
Industry
Eligibility
18 Years to 65 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 12, 2021 · Synced Oct 19, 2026, 10:57 AM EDT
Completed Phase 2 Interventional Results available

Comparing and Combining Bortezomib and Mycophenolate in SSc Pulmonary Fibrosis

NCT02370693
View directory record Official record
Conditions
Lung Diseases, Interstitial, Systemic Sclerosis, Scleroderma
Interventions
Bortezomib, Placebo, Mycophenolate mofetil
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 25, 2021 · Synced Oct 19, 2026, 10:57 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Botulinum Toxin to Improve Cosmesis of Primary Cleft Lip Repair

NCT02247193
View directory record Official record
Conditions
Cleft Lip, Scarring, Cleft Palate
Interventions
Botulinum Toxin Type A, Normal Saline Injection
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
Up to 6 Months
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2020
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 3, 2021 · Synced Oct 19, 2026, 10:57 AM EDT
Recruiting Not applicable Interventional

Microneedling vs Dermabrasion for Early Facial Scar Resurfacing

NCT06171386
View directory record Official record
Conditions
Scar
Interventions
Microneedling, Dermabrasion
Procedure
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Oct 19, 2026, 10:57 AM EDT
Completed Not applicable Interventional

Electrodermabrasion Compared to Dermabrasion

NCT01769989
View directory record Official record
Conditions
Scar
Interventions
Electrodermabrasion, Dermabrasion
Procedure
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated May 30, 2017 · Synced Oct 19, 2026, 10:57 AM EDT
Terminated Phase 2 Interventional

Sorafenib for Patients With Extensive Keloids

NCT01425216
View directory record Official record
Conditions
Keloids
Interventions
Sorafenib
Drug
Lead sponsor
Tirgan, Michael H., M.D.
Individual
Eligibility
18 Years to 50 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 18, 2016 · Synced Oct 19, 2026, 10:57 AM EDT
Completed Not applicable Interventional

A Comparison of Scar Infiltration, Scar Deactivation, and Standard of Care for the Treatment of Chronic, Post-Surgical Pain After Cesarean Section

NCT03936309
View directory record Official record
Conditions
Scar, Cesarean Section; Dehiscence
Interventions
Scar Deactivation Surface Release Technique protocol, Scar Infiltration with 0.25-1% Lidocaine, Physical therapy
Other
Lead sponsor
Jennifer Loomis
Federal
Eligibility
18 Years and older · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Scott Air Force Base, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 9, 2025 · Synced Oct 19, 2026, 10:57 AM EDT
Not listed No phase listed Observational

Superficial Radiation Therapy (SRT) for the Treatment of Recurrent Keloid Scars

NCT04184011
View directory record Official record
Conditions
Keloid Scar
Interventions
SRT-100™
Device
Lead sponsor
Sensus Healthcare
Industry
Eligibility
Not listed
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Boynton Beach, Florida
Source: ClinicalTrials.gov public record
Updated Dec 3, 2019 · Synced Oct 19, 2026, 10:57 AM EDT
Recruiting Phase 3 Interventional

Study to Learn About the Safety of Fazirsiran and if it Can Help People With Alpha-1 Antitrypsin Liver Disease With Mild Liver Scarring (Fibrosis)

NCT06165341
View directory record Official record
Conditions
Alpha1-Antitrypsin Deficiency
Interventions
Fazirsiran Injection, Placebo
Drug
Lead sponsor
Takeda
Industry
Eligibility
18 Years to 75 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
20
States / cities
Phoenix, Arizona • Tucson, Arizona • La Jolla, California + 15 more
Source: ClinicalTrials.gov public record
Updated Mar 5, 2026 · Synced Oct 19, 2026, 10:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Post Excision/Mohs Scar Laser Resurfacing

NCT02130297
View directory record Official record
Conditions
Skin Cancer
Interventions
Laser Treatment
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 19, 2021 · Synced Oct 19, 2026, 10:57 AM EDT
Completed Not applicable Interventional

Mederma to Reduce Appearance of Post Surgical Scars

NCT01504061
View directory record Official record
Conditions
Scars
Interventions
Mederma N&I, Mederma Ultra Gel
Other
Lead sponsor
Merz North America, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 24, 2013 · Synced Oct 19, 2026, 10:57 AM EDT
Terminated Phase 2 Interventional Results available

A Phase 2 Extension Study To Enroll Subjects Who Were Enrolled In B5301001 Study

NCT02205476
View directory record Official record
Conditions
Hypertrophic Scars Resulting From Prior Breast Scar Revision Surgery
Interventions
PF-06473871
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 57 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
5
States / cities
Coral Gables, Florida • Miami, Florida • Atlanta, Georgia + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 28, 2016 · Synced Oct 19, 2026, 10:57 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Patient Satisfaction and Cosmetic Outcomes in Adhesive Strip Versus Suture Repair for Simple Facial Lacerations

NCT06550999
View directory record Official record
Conditions
Facial Laceration
Interventions
Laceration repair with adhesive strips, Laceration repair with sutures
Device · Procedure
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Enrollment
62 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced Oct 19, 2026, 10:57 AM EDT
Not yet recruiting Early Phase 1 Interventional

Topical CBD Scar Outcomes Study

NCT05650697
View directory record Official record
Conditions
Forehead; Wound
Interventions
Group 1 cannabidiol (CBD) with silicone ointment, Group 2 silicone patch
Biological
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 99 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Apr 1, 2026 · Synced Oct 19, 2026, 10:57 AM EDT