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ClinicalTrials.gov public records Last synced Oct 7, 2026, 6:23 AM EDT

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Showing 265–278 of 278 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Cigarette Smokers Clear all

Conditions: Smoking, Cigarette, Nicotine Dependence
Interventions: Nicotine (electronic cigarette), Nicotine (nicotine pouch); Other
Lead sponsor: Brown University; Other
Eligibility: 21 Years and older
Enrollment: 45 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Stress, Smoking Cessation, Overeating
Interventions: Prompt to use smartphone apps for stress management; Behavioral
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 75 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Electronic Cigarette Use
Interventions: Tobacco product administration and assessment, own brand cigarettes, Tobacco product administration and assessment, ECIG 30 Watts, 0 mg/ml nicotine, Tobacco product administration and assessment, ECIG 30 Watts, 8 mg/ml nicotine, Tobacco product administration and assessment, ECIG 30 Watts, 15 mg/ml nicotine, Tobacco product administration and assessment, ECIG 30 Watts, 30 mg/ml nicotine; Other
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 18 Years to 55 Years
Enrollment: 44 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: Smoking, Tobacco
Interventions: 31237616, 31237617, 31237571, 31237581; Other
Lead sponsor: RAI Services Company; Industry
Eligibility: 21 Years to 65 Years
Enrollment: 1,060 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026
U.S. locations: 9
States / cities: Brandon, Florida • Coral Springs, Florida • Aurora, Illinois + 5 more

Conditions: Smoker, Smoking Cessation
Interventions: Nicotine Pouches, Mini Nicotine lozenges; Drug
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 21 Years and older
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Smoking
Interventions: Nicotine Lozenge, Placebo Lozenge, Abstinence Advisement; Drug · Behavioral
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 46 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2013
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: Non-interventional study.; Other
Lead sponsor: GlaxoSmithKline; Industry
Eligibility: 40 Years and older
Enrollment: 1,283 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007
U.S. locations: 47
States / cities: Highlands Ranch, Colorado • Wheat Ridge, Colorado • Clearwater, Florida + 43 more

Conditions: Tobacco Use Disorder
Interventions: switch to non-menthol cigarettes prior to cessation attempt, continue smoking menthol cigarettes prior to cessation attempt; Other
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years to 64 Years
Enrollment: 122 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2018
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Tobacco Dependence
Interventions: Reduced Nicotine Content Cigarettes, Same Nicotine Content Cigarettes; Drug
Lead sponsor: Milton S. Hershey Medical Center; Other
Eligibility: 18 Years to 65 Years
Enrollment: 280 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2018
U.S. locations: 2
States / cities: Washington D.C., District of Columbia • Hershey, Pennsylvania

Conditions: Obesity, Smoking Cessation
Interventions: ENDS, CI, No ENDS, NI; Other
Lead sponsor: Brown University; Other
Eligibility: 21 Years to 99 Years
Enrollment: 39 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Nicotine Dependence
Interventions: Exposure to smoking advertising with coupon, Exposure to smoking advertising without coupons, Exposure to non health related images; Behavioral
Lead sponsor: National Institute on Minority Health and Health Disparities (NIMHD); NIH
Eligibility: 18 Years to 29 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Smoking
Interventions: FT21039, FT21092, FT21018; Other
Lead sponsor: RAI Services Company; Industry
Eligibility: 21 Years to 60 Years
Enrollment: 114 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017
U.S. locations: 2
States / cities: Overland Park, Kansas • Minneapolis, Minnesota

Conditions: Cigarette Smoker, Current Every Day Smoker
Interventions: Informational Intervention, Telephone-Based Intervention; Other · Behavioral
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: Not listed
Enrollment: 46 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Tobacco Use
Interventions: VLN menthol cigarettes (A), Usual Brand Menthol Cigarettes (B), Nicotine gum (C); Other · Drug
Lead sponsor: 22nd Century Group, Inc.; Industry
Eligibility: 22 Years to 65 Years
Enrollment: 55 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018
U.S. locations: 1
States / cities: Overland Park, Kansas

Search by objective public record fields.

Using ANDS to Reduce Harm for Low SES Cigarette Smokers

Sense2Stop:Mobile Sensor Data to Knowledge

Effects of E-Cigarette Nicotine Content in Smokers (Nicotine Flux Study)

A Multi-Site Study to Assess the Effect of Availability of a Heated Tobacco Product on Smoking Abstinence Among Current Primary Cigarette Smokers

The Options 2 Study

Pilot Study: Preoperative Nicotine Lozenges

Airway Limitation Study: Study In Primary Care Centers Of Chronic Bronchitis In Long-Term Cigarette Smokers Of At Least 40 Years Of Age With Symptoms Of Cough And Shortness Of Breath

Smoking Cessation in Menthol Flavored Cigarette Smokers

Reduced Nicotine Content Cigarettes in Smokers of Lower Socioeconomic Status

Trial for Harm Reduction With Incentives & Vaping E-cigarettes

Understanding How Cigarette Direct Mail Marketing Influences Smoking Behaviors Among High and Low Socioeconomic Status Young Adult Smokers

CSD170501: Study to Assess Biomarkers of Tobacco Exposure in Smokers During In-Clinic Confinement Switch to an Electronic Cigarette

Tailored Smoking Cessation Intervention in Promoting Sexual and Gender Minority Smokers to Quit Smoking

Evaluation of Abuse Liability of Very Low Nicotine (VLN) Mentholated Cigarettes