Independent directory Public ClinicalTrials.gov records United States
Clinical Trials Finder
Objective public record navigation
Search Results

Search by objective public record fields.

Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results come from ClinicalTrials.gov. When the live registry is unavailable, a clearly labeled stored copy may be shown.

Clear filters

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Oct 27, 2026, 12:23 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 217–240 of 687 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Cigarette Use Clear all
Completed Not applicable Interventional Accepts healthy volunteers

E-cigarette Switching Older Adults

NCT06534905
View directory record Official record
Conditions
Tobacco Use, Opioid Use Disorder, Tobacco-Related Disorders
Interventions
E-cigarette, Control/Standard Advice
Other · Behavioral
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
50 Years and older
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 10, 2026 · Synced Oct 27, 2026, 12:23 AM EDT
Enrolling by invitation Phase 4 Interventional

Piloting Novel Interventional Strategies to Improve Nicotine Pouches as a Substitute for Smoking

NCT07625956
View directory record Official record
Conditions
Smoking ( Cigarette)
Interventions
Nicotine replacement therapy patches, Oral nicotine pouches
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
21 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Oct 27, 2026, 12:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Impact of Oral Ethanol and Vaped Ethanol on the Evaluation of Impairment

NCT04522973
View directory record Official record
Conditions
Electronic Cigarette Use
Interventions
Beverage with ethanol and E-cigarette liquid with ethanol, Beverage with ethanol and E-cigarette liquid without ethanol, Beverage without ethanol and E-cigarette liquid with ethanol, Beverage without ethanol and E-cigarette liquid without ethanol
Other
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
21 Years to 55 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jan 14, 2026 · Synced Oct 27, 2026, 12:23 AM EDT
Completed Not applicable Interventional Results available

Evaluating E-Cigarette Nicotine Form, Concentration, and Flavors Among Youth

NCT05458895
View directory record Official record
Conditions
E-cigarette Use
Interventions
ECIG lab session 1, ECIG lab session 2, ECIG lab session 3, ECIG lab session 4, ECIG lab session 5, ECIG lab session 6, ECIG lab session 7, ECIG lab session 8
Other
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
21 Years to 25 Years
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 22, 2024 · Synced Oct 27, 2026, 12:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

E-cigarettes and Blood Vessel Function

NCT02740595
View directory record Official record
Conditions
Nicotine Dependence
Interventions
one time exposure to e-cig with nicotine, one time exposure to e-cig without nicotine, one time exposure to empty e-cig
Other
Lead sponsor
University of California, Los Angeles
Other
Eligibility
21 Years to 45 Years
Enrollment
148 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2022
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 5, 2023 · Synced Oct 27, 2026, 12:23 AM EDT
Withdrawn Phase 1 Interventional Accepts healthy volunteers

Investigation of the Impact of Smoking Status on Allergen-induced Nasal Airway Inflammation Using a Cat Hair (Felis Domesticus) Extract Nasal Allergen Challenge Model

NCT03031145
View directory record Official record
Conditions
Tobacco Smoking, Healthy Participants, E-cigarette Smokers
Interventions
Felis Domesticus
Biological
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 50 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated May 7, 2021 · Synced Oct 27, 2026, 12:23 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

A Study Evaluating the Use of an Indoor Air Quality Monitor to Promote a Smoke-free Home

NCT06693700
View directory record Official record
Conditions
Smoking, Smoking Cessation, Smoking Reduction, Smoking Habit, Smoking Behaviors, Smoking, Tobacco, Smoking, Cigarette, Smoking (Tobacco) Addiction, Tobacco Use, Tobacco Smoking
Interventions
Indoor Air Quality Monitor AirGradient ONE
Other
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
8
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Oct 27, 2026, 12:23 AM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

Semaglutide for Post-Smoking Cessation Weight Management

NCT06173778
View directory record Official record
Conditions
Obesity, Overweight, Cigarette Smoking
Interventions
semaglutide 2.4mg, Placebo, Nicotine Replacement Therapy (NRT, nicotine patch), Brief Smoking Cessation Counseling
Drug · Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 75 Years
Enrollment
197 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
2
States / cities
Austin, Texas • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 27, 2026, 12:23 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Effect of Electronic Cigarette Use on Cough Reflex Sensitivity

NCT02203162
View directory record Official record
Conditions
Cough
Interventions
electronic cigarette exposure
Device
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Jun 28, 2023 · Synced Oct 27, 2026, 12:23 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Quit Smoking Study for People Who Use E-Cigarettes

NCT04946825
View directory record Official record
Conditions
Nicotine Addiction, E-Cig Use, Quitting Smoking
Interventions
Nicotine replacement therapy patch, Nicotine replacement therapy lozenge, Quit electronic cigarettes, Continue electronic cigarettes
Drug · Behavioral
Lead sponsor
University of Vermont
Other
Eligibility
18 Years to 29 Years
Enrollment
396 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated May 22, 2025 · Synced Oct 27, 2026, 12:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Nicotine Uptake, Measures of Abuse Liability, and Puffing Topography With Use of RELX ENDS Products by Smokers

NCT04640285
View directory record Official record
Conditions
Electronic Cigarette Use
Interventions
RELX ENDS Tobacco Flavor, RELX ENDS Menthol Flavor, Usual Brand Cigarette, Nicorette White Ice Mint nicotine polacrilex gum
Other
Lead sponsor
Cheerain HK Limited
Industry
Eligibility
22 Years to 59 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Overland Park, Kansas
Source: ClinicalTrials.gov public record
Updated Mar 24, 2021 · Synced Oct 27, 2026, 12:23 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Impact of Very Low Nicotine Content Cigarettes in a Complex Marketplace

NCT03272685
View directory record Official record
Conditions
Tobacco Smoking, Nicotine Dependence
Interventions
Very Low Nicotine Content Cigarettes, Normal Nicotine Content Cigarettes
Drug
Lead sponsor
University of Minnesota
Other
Eligibility
21 Years and older
Enrollment
799 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
6
States / cities
San Francisco, California • Minneapolis, Minnesota • Durham, North Carolina + 3 more
Source: ClinicalTrials.gov public record
Updated Aug 20, 2024 · Synced Oct 27, 2026, 12:23 AM EDT
Completed Not applicable Interventional Results available

Pharmacokinetic and Subjective Effects of Heated Tobacco Products

NCT06356610
View directory record Official record
Conditions
Tobacco Use
Interventions
Product A, Product B, Product C, Product D, Product E, Product F
Other
Lead sponsor
Altria Client Services LLC
Industry
Eligibility
22 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
3
States / cities
Lexington, Kentucky • Springfield, Missouri • Knoxville, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 27, 2026 · Synced Oct 27, 2026, 12:23 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Effects of Contingency Management and Nicotine Replacement Therapy on Youth Smoking

NCT01359709
View directory record Official record
Conditions
Cigarette Smoking Behavior
Interventions
Nicotine polacrilex
Drug
Lead sponsor
University of California, Los Angeles
Other
Eligibility
13 Years to 21 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2016
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 13, 2016 · Synced Oct 27, 2026, 12:23 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

RTMS Targets Neural Circuits for Smoking Cessation

NCT04903028
View directory record Official record
Conditions
Tobacco Use, Cigarette Smoking
Interventions
Sham rTMS, Active rTMS 10 Hz DLPFC
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
22 Years to 70 Years
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 16, 2026 · Synced Oct 27, 2026, 12:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Cardiovascular Assessment of the Effects of Tobacco and Nicotine Delivery Products

NCT01964807
View directory record Official record
Conditions
Adverse Effect of Other Agents Primarily Affecting the Cardiovascular System, Initial Encounter
Interventions
Cigarette, NIDA test type with 16.6 mg nicotine, Cigarette, NIDA test type with <0.45 mg nicotine, Electronic cigarette with 18 mg/ml nicotine, Electronic Cigarette with no nicotine, Moist snuff, Sham Smoking, Secondhand cigarette smoke (SHS), Conditioned, filtered air, Sham Moist Snuff
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 50 Years
Enrollment
81 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2021
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Dec 27, 2021 · Synced Oct 27, 2026, 12:23 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Multimodal Neuroimaging Genetic Biomarkers of Nicotine AddictionSeverity

NCT01867411
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Not listed
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
18 Years to 60 Years
Enrollment
159 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2013
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 26, 2026 · Synced Oct 27, 2026, 12:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Enhancing Source Credibility in Tobacco Regulatory Communications

NCT03339206
View directory record Official record
Conditions
Cigarette Smoking Behavior
Interventions
Constituent message with FDA and quitline, Constituent message without FDA and quitline, Littering message (Control)
Behavioral
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
18 Years to 65 Years
Enrollment
845 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 24, 2020 · Synced Oct 27, 2026, 12:23 AM EDT
Recruiting Phase 1Phase 2 Interventional Accepts healthy volunteers

Hyperpolarized Xenon-129 MR Imaging of the Lung

NCT04662658
View directory record Official record
Conditions
E-Cig Use
Interventions
Hyperpolarized Xenon -129 MRI
Drug
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Dec 10, 2020 · Synced Oct 27, 2026, 12:23 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Sex Differences in E-Cigarette Perception

NCT07398976
View directory record Official record
Conditions
Nicotine Dependence, E-cigarette Use
Interventions
Nicotine Level 1 (0mg/ml), Nicotine Level 2 (36mg/ml), Nicotine Level 3 (59mg/ml)
Other
Lead sponsor
Yale University
Other
Eligibility
21 Years to 44 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Oct 27, 2026, 12:23 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Concurrent Nicotine Patch / Denicotinized Cigarette Therapy for Smoking Cessation II

NCT00734617
View directory record Official record
Conditions
Cigarette Smoking
Interventions
Nicotine Patch
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years to 65 Years
Enrollment
479 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 15, 2014 · Synced Oct 27, 2026, 12:23 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Predictors of Teen Smoking-cessation

NCT01141517
View directory record Official record
Conditions
Cigarette Smoking
Interventions
Not-On-Tobacco smoking cessation program
Behavioral
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
13 Years to 19 Years
Enrollment
147 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2014
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 22, 2019 · Synced Oct 27, 2026, 12:23 AM EDT
Recruiting Not applicable Interventional

Generalized and Domain-Specific Episodic Thinking for Smoking Cessation

NCT07158749
View directory record Official record
Conditions
Cigarette Smoking Behavior
Interventions
Episodic Future Thinking (EFT), Episodic Recent Thinking (ERT), Domain-specific episodic thinking, Generalized episodic thinking
Behavioral
Lead sponsor
Virginia Polytechnic Institute and State University
Other
Eligibility
21 Years and older
Enrollment
134 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 27, 2026, 12:23 AM EDT
Completed Phase 2 Interventional Results available

Enhancing Self Regulation Among Smokers

NCT04161144
View directory record Official record
Conditions
Smoking Cessation, Smoking, Cigarette, Nicotine Dependence
Interventions
sirolimus, Placebo
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Mar 9, 2021 · Synced Oct 27, 2026, 12:23 AM EDT