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ClinicalTrials.gov public records Last synced Oct 21, 2026, 10:35 PM EDT

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Showing 73–96 of 258 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Circadian Rhythms Clear all
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

Mechanistic Studies of Psilocybin in Headache Disorders

NCT06464367
View directory record Official record
Conditions
Migraine
Interventions
Psilocybin, Placebo
Drug
Lead sponsor
Yale University
Other
Eligibility
21 Years to 70 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Oct 21, 2026, 10:35 PM EDT
Terminated Phase 2 Interventional Results available

A Study to Assess the Wakefulness Promoting Effect, Safety, Tolerability, and Pharmacokinetics (PK) of LML134 in Shift Work Disorder

NCT03141086
View directory record Official record
Conditions
Circadian Rhythm Disorders
Interventions
LML134, Placebo
Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
18 Years to 65 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
8
States / cities
Los Angeles, California • San Diego, California • Miami, Florida + 5 more
Source: ClinicalTrials.gov public record
Updated Jan 5, 2021 · Synced Oct 21, 2026, 10:35 PM EDT
Completed Not applicable Interventional

Time Restricted Nutrition in Pediatric Stem Cell Transplant Recipients

NCT04549038
View directory record Official record
Conditions
Hematopoietic Stem Cell Transplant
Interventions
12-16 hour nutrition
Other
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
12 Months and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 8, 2023 · Synced Oct 21, 2026, 10:35 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Circadian Rhythms in Human Adipose

NCT06891534
View directory record Official record
Conditions
Obesity, Abdominal, Feeding Patterns
Interventions
Continuous Feeding, Intermittent feeding
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 55 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2030
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Oct 21, 2026, 10:35 PM EDT
Completed Phase 4 Interventional

Lemborexant in Delayed Sleep Phase Syndrome

NCT05463861
View directory record Official record
Conditions
Delayed Sleep Phase Syndrome
Interventions
Lemborexant, Placebo
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Redwood City, California
Source: ClinicalTrials.gov public record
Updated Mar 2, 2026 · Synced Oct 21, 2026, 10:35 PM EDT
Not listed Not applicable Interventional

Impact of Time Restricted Eating on Patients With Coronary Artery Disease (CAD) Undergoing Cardiac Rehabilitation

NCT05014880
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
ICR (Intensive Cardiac Rehabilitation), ICR x TRE (Intensive Cardiac Rehabilitation x Time-Restricted Eating)
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 75 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Aug 20, 2024 · Synced Oct 21, 2026, 10:35 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Multi-scale Modeling of Sleep Behaviors in Social Networks

NCT02846077
View directory record Official record
Conditions
Healthy Volunteers
Interventions
No intervention. Observation only
Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
729 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 11, 2018 · Synced Oct 21, 2026, 10:35 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

A Pilot Study on Diurnal Variation

NCT01806051
View directory record Official record
Conditions
Phenylketonuria (PKU)
Interventions
Kuvan
Drug
Lead sponsor
Dr. Linda Randolph
Other
Eligibility
4 Years and older
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 20, 2016 · Synced Oct 21, 2026, 10:35 PM EDT
Recruiting Not applicable Interventional

Sleep and Circadian Mechanisms in Hypertension

NCT05184933
View directory record Official record
Conditions
Hypertension, Cardiovascular Diseases, Cardiovascular Risk Factors, Circadian Rhythms, Sleep
Interventions
At-home Polysomnography, Circadian Protocol, Rested Wakefulness Trial, Overnight Sleep Trial, Regularized Sleep Schedule
Other · Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
25 Years to 64 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2029
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Feb 11, 2026 · Synced Oct 21, 2026, 10:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Simulated Dawn Med Students

NCT02088593
View directory record Official record
Conditions
Depression, Anxiety, Fatigue, Sleepiness, Sleep Disruption
Interventions
Simulated Dawn Light Box, Sleep Hygiene instructions
Device · Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2010
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated May 24, 2023 · Synced Oct 21, 2026, 10:35 PM EDT
Recruiting No phase listed Observational

Patient Registry of Blind Subjects With Sleep-related Problems

NCT01195558
View directory record Official record
Conditions
Sleep-wake Disorder in Blind Individuals
Interventions
Data collection on blindness and sleep problems
Other
Lead sponsor
Vanda Pharmaceuticals
Industry
Eligibility
Not listed
Enrollment
10,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2030
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jun 24, 2020 · Synced Oct 21, 2026, 10:35 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Evaluation of the Reliability and Validity of a Diagnostic Sleep Disorders Questionnaire

NCT03468400
View directory record Official record
Conditions
Sleep Apnea Syndromes, Insomnia, Insufficient Sleep Syndrome, Circadian Rhythm Disorders
Interventions
Not listed
Lead sponsor
Dayzz Live Well Ltd.
Industry
Eligibility
21 Years to 65 Years
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 22, 2020 · Synced Oct 21, 2026, 10:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Fuel and Rhythm (FAR) Phase 2 Study

NCT05482711
View directory record Official record
Conditions
Aging
Interventions
Time Restricted Eating Intervention
Other
Lead sponsor
University of Florida
Other
Eligibility
65 Years and older
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Oct 21, 2026, 10:35 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Does Circadian Misalignment Have Sex-Specific Effects on Metabolism?

NCT07441265
View directory record Official record
Conditions
Circadian Misalignment, Sex Differences
Interventions
Day shift, Night shift
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 40 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 27, 2026 · Synced Oct 21, 2026, 10:35 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

The Incidence of Breast and Other Cancers Among Female Flight Attendants

NCT00342407
View directory record Official record
Conditions
Thyroid Cancer, Breast Cancer, Non-Melanoma Skin Cancer, Melanoma
Interventions
Not listed
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years to 100 Years · Female only
Enrollment
6,093 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2020
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 10, 2020 · Synced Oct 21, 2026, 10:35 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Diurnal Variation of Tear Meniscus and Tear Osmolarity

NCT01206244
View directory record Official record
Conditions
Dry Eye
Interventions
Not listed
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jun 13, 2013 · Synced Oct 21, 2026, 10:35 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Effects of Chronic Sleep Restriction in Young and Older People

NCT00506428
View directory record Official record
Conditions
Aging, Sleep Deprivation, Metabolic Syndrome
Interventions
chronic sleep restriction
Behavioral
Lead sponsor
National Institute on Aging (NIA)
NIH
Eligibility
18 Years to 70 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2011
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 29, 2009 · Synced Oct 21, 2026, 10:35 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Shift Work, Heredity, Insulin, and Food Timing Study

NCT02997319
View directory record Official record
Conditions
Shift Work Type Circadian Rhythm Sleep Disorder, Diabetes Mellitus, Type 2, Circadian Rhythm Sleep Disorder, Shift Work Type, Insulin Resistance
Interventions
Not listed
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 60 Years
Enrollment
365 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 19, 2021 · Synced Oct 21, 2026, 10:35 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Eating Behaviors in Shift Workers

NCT04468672
View directory record Official record
Conditions
Shift Work Type Circadian Rhythm Sleep Disorder, Eating Behavior
Interventions
Portion size
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
20 Years to 55 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 25, 2026 · Synced Oct 21, 2026, 10:35 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Safety and Efficacy of Ramelteon in Healthy Subjects

NCT00671190
View directory record Official record
Conditions
Sleep Disorder
Interventions
Ramelteon, Placebo
Drug
Lead sponsor
Takeda
Industry
Eligibility
18 Years to 45 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005
U.S. locations
13
States / cities
Hot Springs, Arkansas • Los Angeles, California • San Diego, California + 10 more
Source: ClinicalTrials.gov public record
Updated Feb 28, 2012 · Synced Oct 21, 2026, 10:35 PM EDT
Completed No phase listed Observational

Study of Sleep and Delirium in the Intensive Care Unit (ICU)

NCT01280097
View directory record Official record
Conditions
Delirium, Sleep Disorders, Circadian Rhythm
Interventions
Not listed
Lead sponsor
University of California, San Francisco
Other
Eligibility
45 Years and older
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 15, 2015 · Synced Oct 21, 2026, 10:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Interaction of Melatonin With MTNR1B Genotype on Glucose Control - Study 2

NCT03464084
View directory record Official record
Conditions
Glucose, Circadian Rhythm, Melatonin, Genes, Light
Interventions
placebo, melatonin, bright light, dim light
Drug · Dietary Supplement · Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
21 Years to 55 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 26, 2022 · Synced Oct 21, 2026, 10:35 PM EDT
Active, not recruiting Phase 1Phase 2 Interventional

Towards Understanding Between ADT Treatment, Circadian Rhythm, and Physiological Responsiveness

NCT05968144
View directory record Official record
Conditions
Prostatic Neoplasm, Survivorship, Frailty, Aging, Metastatic Breast Cancer
Interventions
Dietary recommendations, Time-restricted eating
Behavioral
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
55 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 27, 2026 · Synced Oct 21, 2026, 10:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Music, Sleep and Dementia Study

NCT04157244
View directory record Official record
Conditions
Dementia, Alzheimer Disease, Circadian Rhythm Disorders, Circadian Rhythm Sleep Disorder, Insomnia, Hypersomnia, Cognitive Impairment, Cognitive Decline, Mild Cognitive Impairment, Frontotemporal Dementia, Neurocognitive Disorders, Vascular Dementia, Sleep Disorder, Memory Impairment
Interventions
Tailored music listening intervention
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 110 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 13, 2021 · Synced Oct 21, 2026, 10:35 PM EDT