- Conditions
- Opioid-use Disorder, Addiction, Depression, Post Traumatic Stress Disorder, Suicidal Ideation
- Interventions
- Collaborative care Plus
- Behavioral
- Lead sponsor
- RAND
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 68 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2024
- U.S. locations
- 12
- States / cities
- Los Angeles, California • Santa Monica, California • Albuquerque, New Mexico + 3 more
Search Results
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Showing 1–24
of 54
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Opioid Use Disorder, Posttraumatic Stress Disorder (PTSD)
- Interventions
- HOPE Therapy
- Behavioral
- Lead sponsor
- Medical University of South Carolina
- Other
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 76 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- Charleston, South Carolina
- Conditions
- Post-traumatic Stress Disorder (PTSD), Post-traumatic Stress Symptoms, Opioid Use Disorder (OUD), Stimulant Use Disorder, Stimulant Use & Co-occuring Opioid Use Disorders, Co-occurring Mental and Substance Use Disorders, Medications for Opioid Use Disorder
- Interventions
- Cognitive Processing Therapy (CPT), Written Exposure Therapy (WET)
- Other
- Lead sponsor
- University of Arkansas
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 338 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2029
- U.S. locations
- 2
- States / cities
- Little Rock, Arkansas
- Conditions
- Adolescent Substance Abuse, Attention Deficit Hyperactivity Disorder
- Interventions
- Medication integration protocol
- Behavioral
- Lead sponsor
- The National Center on Addiction and Substance Abuse at Columbia University
- Other
- Eligibility
- 13 Years to 17 Years
- Enrollment
- 14 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2014
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Co-occurring Mental and Substance Use Disorders, Crime, Criminogenic Thinking, Implementation, Adaptation
- Interventions
- Dual-diagnosis motivational interviewing (DDMI), Integrated group therapy (IGT), Jail and community-based behavioral health services
- Behavioral
- Lead sponsor
- RTI International
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 8 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2019
- U.S. locations
- 1
- States / cities
- Research Triangle Park, North Carolina
- Conditions
- Stress Disorders, Post-Traumatic, Opioid Use Disorder
- Interventions
- MDMA Assisted Therapy
- Drug
- Lead sponsor
- University of New Mexico
- Other
- Eligibility
- 18 Years and older · Female only
- Enrollment
- 15 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2027
- U.S. locations
- 1
- States / cities
- Albuquerque, New Mexico
- Conditions
- Alcohol Use Disorder (AUD), Post Traumatic Stress Disorder (PTSD), Insomnia
- Interventions
- Suvorexant, Placebo
- Drug · Other
- Lead sponsor
- Pharmacotherapies for Alcohol and Substance Use Disorders Alliance
- Other
- Eligibility
- 21 Years to 65 Years
- Enrollment
- 76 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 2
- States / cities
- Los Angeles, California • Houston, Texas
- Conditions
- Posttraumatic Stress Disorder, Alcohol Use Disorder
- Interventions
- Cognitive Processing Therapy + Relapse Prevention, Relapse Prevention
- Behavioral
- Lead sponsor
- Texas A&M University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2028
- U.S. locations
- 2
- States / cities
- Charleston, South Carolina • College Station, Texas
- Conditions
- Substance Use Disorders, Bipolar Disorder, Mood Disorders
- Interventions
- Quetiapine, Placebo
- Drug · Other
- Lead sponsor
- Boston Medical Center
- Other
- Eligibility
- 15 Years to 24 Years
- Enrollment
- 24 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2021
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Substance Use Disorder, Posttraumatic Stress Disorder
- Interventions
- Prolonged Exposure with Contingency Management, Standard Care
- Behavioral
- Lead sponsor
- UConn Health
- Other
- Eligibility
- 18 Years to 25 Years
- Enrollment
- 27 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2021
- U.S. locations
- 3
- States / cities
- Farmington, Connecticut • Hartford, Connecticut • New Britain, Connecticut
- Conditions
- Concussion, Mild Traumatic Brain Injury, Brain Injury, Traumatic Brain Injury, Substance Use, Substance Use Disorder (SUD)
- Interventions
- Integrated Model of Care
- Other
- Lead sponsor
- Shepherd Center, Atlanta GA
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 360 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2028
- U.S. locations
- 1
- States / cities
- Atlanta, Georgia
- Conditions
- Mental Health Disorders, Substance Use Disorders
- Interventions
- Full MISSION, Linkage Only Delivered by a Peer Specialist
- Behavioral
- Lead sponsor
- University of Massachusetts, Worcester
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 208 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2026
- U.S. locations
- 1
- States / cities
- Worcester, Massachusetts
- Conditions
- Substance Use Disorders, Posttraumatic Stress Disorder
- Interventions
- Written Exposure Therapy, Neutral Topic Writing
- Behavioral
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- 18 Years and older
- Enrollment
- 170 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2027
- U.S. locations
- 1
- States / cities
- West Haven, Connecticut
- Conditions
- Cannabis-Related Disorder, Substance-Related Disorders, Schizophrenia, Psychotic Disorders
- Interventions
- clozapine, risperidone
- Drug
- Lead sponsor
- Dartmouth-Hitchcock Medical Center
- Other
- Eligibility
- 17 Years to 45 Years
- Enrollment
- 14 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2011
- U.S. locations
- 5
- States / cities
- Concord, New Hampshire • Lebanon, New Hampshire • Manchester, New Hampshire + 1 more
- Conditions
- Post Traumatic Stress Disorder, Alcohol Use Disorder
- Interventions
- Zonisamide, Placebo Comparator
- Drug
- Lead sponsor
- Pharmacotherapies for Alcohol and Substance Use Disorders Alliance
- Other
- Eligibility
- 18 Years to 55 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Posttraumatic Stress Disorder, Opioid Use Disorder
- Interventions
- Sparrow Ascent tAN, Sparrow Ascent Active Sham
- Device
- Lead sponsor
- University of Cincinnati
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 1
- States / cities
- Cape Girardeau, Missouri
- Conditions
- Opioid-use Disorder, Addiction, Depression, Post-traumatic Stress Disorder
- Interventions
- Collaborative Care
- Behavioral
- Lead sponsor
- RAND
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 729 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2024
- U.S. locations
- 16
- States / cities
- Los Angeles, California • Santa Monica, California • Albuquerque, New Mexico + 5 more
- Conditions
- Chronic Pain, Opioid-use Disorder, Opioids; Harmful Use
- Interventions
- ACT+MBRP, Education control
- Behavioral
- Lead sponsor
- University of New Mexico
- Other
- Eligibility
- 21 Years to 75 Years
- Enrollment
- 157 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2026
- U.S. locations
- 4
- States / cities
- San Francisco, California • Albuquerque, New Mexico • Tacoma, Washington
- Conditions
- Alcohol Abuse, Posttraumatic Stress Disorder
- Interventions
- Prazosin, Placebo medication
- Drug
- Lead sponsor
- Seattle Institute for Biomedical and Clinical Research
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2012
- U.S. locations
- 1
- States / cities
- Seattle, Washington
- Conditions
- PTSD, Substance Use Disorders
- Interventions
- Cognitive behavioral therapy for PTSD
- Behavioral
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- 18 Years and older
- Enrollment
- 129 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2017
- U.S. locations
- 3
- States / cities
- Tampa, Florida • Syracuse, New York • White River Junction, Vermont
- Conditions
- Anxiety Disorder, Posttraumatic Stress Disorder, Hazardous Drinking
- Interventions
- Unified Protocol- Alcohol, Usual care
- Behavioral
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- 18 Years and older
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2026
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Substance Use Disorder, Post-traumatic Stress Disorder, Moral Injury
- Interventions
- Mindful Self-Compassion
- Behavioral
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- 18 Years and older
- Enrollment
- 34 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2021
- U.S. locations
- 1
- States / cities
- Providence, Rhode Island
- Conditions
- Co-Occurring Disorders, Homelessness, Substance Abuse Disorder, Mental Illness
- Interventions
- Not listed
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- Not listed
- Enrollment
- 108 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2020
- U.S. locations
- 1
- States / cities
- Bedford, Massachusetts
- Conditions
- Substance Use, Mental Health Issue
- Interventions
- ePACE Personalized Intervention, eFACE Fixed Intervention
- Behavioral
- Lead sponsor
- Oregon Research Institute
- Other
- Eligibility
- 12 Years and older
- Enrollment
- 120 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2025
- U.S. locations
- 1
- States / cities
- Albuquerque, New Mexico