- Conditions
- MCI, Aging
- Interventions
- Novel CogXergaming Training, Exercise and Education Training Program
- Behavioral
- Lead sponsor
- University of Illinois at Chicago
- Other
- Eligibility
- 55 Years to 90 Years
- Enrollment
- 46 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
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Showing 25–48
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- Conditions
- Cognitive Change, Cognitive Impairment, Mild, Aging
- Interventions
- Piano Training
- Behavioral
- Lead sponsor
- University of Georgia
- Other
- Eligibility
- 65 Years and older
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2023
- U.S. locations
- 1
- States / cities
- Athens, Georgia
- Conditions
- Dementia, Dementia, Vascular, Mixed Dementias, Alzheimer Disease, Huntington Disease, Lewy Body Disease, Creutzfeldt-Jakob Syndrome, Frontotemporal Lobar Degeneration, Cognitive Dysfunction, Cognitive Aging, Chronic Disease, Palliative Care, Patient Care, Health Care Quality, Access, and Evaluation, Patient Care, Health Communication, Patient Care Planning, Quality of Life
- Interventions
- Jumpstart Guide
- Behavioral
- Lead sponsor
- University of Washington
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 1,802 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2027
- U.S. locations
- 3
- States / cities
- Seattle, Washington
- Conditions
- Aging, Cognitive Decline
- Interventions
- Successful aging health education intervention, Hearing intervention
- Other
- Lead sponsor
- Johns Hopkins Bloomberg School of Public Health
- Other
- Eligibility
- 70 Years to 84 Years
- Enrollment
- 977 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2023
- U.S. locations
- 4
- States / cities
- Hagerstown, Maryland • Minneapolis, Minnesota • Jackson, Mississippi + 1 more
- Conditions
- Dementia, Mild Cognitive Impairment
- Interventions
- Nicorandil, Placebo
- Drug
- Lead sponsor
- Gregory Jicha, MD, PhD
- Other
- Eligibility
- 70 Years and older
- Enrollment
- 64 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2026
- U.S. locations
- 1
- States / cities
- Lexington, Kentucky
- Conditions
- Aging, Mild Cognitive Impairment
- Interventions
- Memory retraining exercises, Placebo control memory exercises
- Behavioral
- Lead sponsor
- Kessler Foundation
- Other
- Eligibility
- 65 Years and older
- Enrollment
- 33 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2026
- U.S. locations
- 1
- States / cities
- East Hanover, New Jersey
- Conditions
- Serious Mental Illness, Older Adults
- Interventions
- Hopeful and Healthy Living (HHL)
- Behavioral
- Lead sponsor
- Boston University Charles River Campus
- Other
- Eligibility
- 50 Years and older
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2028
- U.S. locations
- 2
- States / cities
- Boston, Massachusetts
- Conditions
- Aging
- Interventions
- Computerized Plasticity-Based Adaptive Cognitive Training, Educational DVDs
- Other
- Lead sponsor
- Posit Science Corporation
- Industry
- Eligibility
- 60 Years and older
- Enrollment
- 94 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2005 – 2006
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- Long-Term Memory Decline, Mild Cognitive Impairment
- Interventions
- LabyrinthVR software, Placebo Games software, Labyrinth Tablet software, Labyrinth VR wireless
- Behavioral
- Lead sponsor
- University of California, San Francisco
- Other
- Eligibility
- 60 Years to 85 Years
- Enrollment
- 200 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2027
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- Amnestic Mild Cognitive Impairment
- Interventions
- Combined Aerobic and Resistance Exercise, Stretching Exercises, Cognitive Training
- Behavioral
- Lead sponsor
- Palo Alto Veterans Institute for Research
- Other
- Eligibility
- 50 Years to 90 Years
- Enrollment
- 72 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2017
- U.S. locations
- 1
- States / cities
- Palo Alto, California
- Conditions
- Alzheimer Disease
- Interventions
- 18F-MK-6240, Lumbar Puncture (optional)
- Drug · Procedure
- Lead sponsor
- Patrick Lao
- Other
- Eligibility
- 50 Years to 100 Years
- Enrollment
- 71 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2022
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Healthy Aging
- Interventions
- Nicotine patch, oral mecamylamine, placebo
- Drug
- Lead sponsor
- University of Vermont
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 104 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2016 – 2022
- U.S. locations
- 1
- States / cities
- Burlington, Vermont
- Conditions
- Aging, Healthy
- Interventions
- Elamipretide will be supplied as a sterile 5.0 mL single-patient, multi-dose glass vial containing 3.75 mL of elamipretide solution (elamipretide [80 mg/mL], phosphate buffer, and benzyl alcohol)
- Drug
- Lead sponsor
- David Marcinek
- Other
- Eligibility
- 65 Years to 80 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Seattle, Washington
- Conditions
- Healthy Aging
- Interventions
- Mental Exercise
- Behavioral
- Lead sponsor
- University of Colorado, Colorado Springs
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 109 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2023
- U.S. locations
- 1
- States / cities
- Colorado Springs, Colorado
- Conditions
- Aging, Longevity, Biomarkers of Aging
- Interventions
- Psilocybin (Usona Institute)
- Drug
- Lead sponsor
- Charles Raison
- Other
- Eligibility
- 60 Years to 80 Years
- Enrollment
- 50 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- Edwards, Colorado
- Conditions
- Alzheimer's Disease
- Interventions
- Not listed
- Lead sponsor
- University of Kansas Medical Center
- Other
- Eligibility
- 65 Years and older
- Enrollment
- 172 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2004 – 2009
- U.S. locations
- 1
- States / cities
- Kansas City, Kansas
- Conditions
- Traumatic Brain Injury, Aging Related Cognitive Decline
- Interventions
- Active tDCS and Cognitive Training Intervention, Sham tDCS and Cognitive Training Intervention
- Combination Product
- Lead sponsor
- Minneapolis Veterans Affairs Medical Center
- Federal
- Eligibility
- 65 Years and older
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- Minneapolis, Minnesota
- Conditions
- Patient Compliance
- Interventions
- Games, Videos
- Behavioral
- Lead sponsor
- University of Illinois at Urbana-Champaign
- Other
- Eligibility
- 35 Years to 64 Years
- Enrollment
- 233 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2020
- U.S. locations
- 1
- States / cities
- Urbana, Illinois
- Conditions
- Aging, Cognitive Decline, Mild Cognitive Impairment, Dementia, Hearing Loss
- Interventions
- Hearing intervention, Successful aging/delayed hearing intervention
- Other
- Lead sponsor
- Johns Hopkins University
- Other
- Eligibility
- 73 Years and older
- Enrollment
- 629 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2027
- U.S. locations
- 4
- States / cities
- Hagerstown, Maryland • Minneapolis, Minnesota • Jackson, Mississippi + 1 more
- Conditions
- Sleep, Alzheimer Disease, Cognitive Impairment, Aging, CBT
- Interventions
- Sleep intervention, Placebo intervention
- Behavioral
- Lead sponsor
- University of California, San Francisco
- Other
- Eligibility
- 65 Years and older
- Enrollment
- 15 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2024
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- Mild Cognitive Impairment (MCI), Mild Cognitive Impairment (MCI) Due to Alzheimer's Disease, TBI (Traumatic Brain Injury), Aging, Healthy Elderly, Alzheimer&Amp;Amp;#39;s Dementia (AD)
- Interventions
- Mindfulness Intervention, Waitlist then mindfulness
- Behavioral
- Lead sponsor
- VA Boston Healthcare System
- Federal
- Eligibility
- 50 Years to 100 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Aging
- Interventions
- Piano Training, Computer Cognitive Training
- Behavioral
- Lead sponsor
- University of South Florida
- Other
- Eligibility
- 60 Years to 80 Years
- Enrollment
- 93 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015 – 2017
- U.S. locations
- 1
- States / cities
- Tampa, Florida
- Conditions
- Aging, Aging Well, All-Cause Mortality, Mortality, Metabolic Syndrome, Cardiovascular Diseases, Cognitive Dysfunction, Musculoskeletal Diseases, Neoplasms, Frailty, Activities of Daily Living, Health-Related Quality of Life, Disability Physical, Neuro-Degenerative Disease, Dementia
- Interventions
- Comprehensive Multi-System Clinical Screening
- Diagnostic Test
- Lead sponsor
- Longevity Metrics, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 1,000,000 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2099
- U.S. locations
- 1
- States / cities
- Boulder, Colorado
- Conditions
- Aging, Cognitive Impairment, Physical Activity
- Interventions
- Gerofit exercise, Health education
- Behavioral
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- 65 Years and older
- Enrollment
- 150 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2029
- U.S. locations
- 2
- States / cities
- West Los Angeles, California • Baltimore, Maryland