Independent directory Public ClinicalTrials.gov records United States
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Showing 1–24 of 30 matching trials from the live ClinicalTrials.gov search.
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Recruiting Not applicable Interventional Accepts healthy volunteers

Benefits of Nicotinamide Riboside Upon Cognition and Sleep

NCT05500170
Conditions
Cognitive Impairment, Sleep Quality
Interventions
Nicotinamide riboside, Placebo
Dietary Supplement
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
65 Years to 85 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
3
States / cities
Buffalo, New York
Conditions
Schizophrenia
Interventions
D-cycloserine, Cognitive Behavioral Therapy
Drug · Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Not applicable Interventional Accepts healthy volunteers

The Aerobic & Cognitive Exercise Study

NCT02237560
Conditions
Mild Cognitive Impairment, Healthy
Interventions
Cybercycle-Game, Cybercyle-Tour, Game Only
Behavioral
Lead sponsor
Union College, New York
Other
Eligibility
50 Years and older
Enrollment
111 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
12
States / cities
Albany, New York • East Greenbush, New York • Guilderland, New York + 5 more
Withdrawn Not applicable Interventional Accepts healthy volunteers

Investigating the Cognitive and Brain Health Benefits of Lean Pork Consumption

NCT07031076
Conditions
Dietary Intervention, Dietary Proteins, Dietary Assessment, Older Adults (65 Years and Older), Cognitive Ability, General
Interventions
Ready-to-eat lean pork in frozen, 5-oz packages
Dietary Supplement
Lead sponsor
University of Nebraska Lincoln
Other
Eligibility
65 Years to 75 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Lincoln, Nebraska
Conditions
Parkinson's Disease With Cognitive Impairments
Interventions
safinamide, placebo
Drug
Lead sponsor
Newron Pharmaceuticals SPA
Industry
Eligibility
45 Years to 80 Years
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2010
U.S. locations
9
States / cities
Sunnyvale, California • Jacksonville, Florida • Atlanta, Georgia + 5 more
Recruiting Not applicable Interventional

Music for Pain and Dementia

NCT07602283
Conditions
Alzheimer Disease, Dementia, Mild Cognitive Impairment, Peer-bonded Caregiver, Caregiver
Interventions
Drumming session, Music-listening session
Behavioral
Lead sponsor
Yale University
Other
Eligibility
50 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
New Haven, Connecticut
Conditions
Healthy Aging, Cognitive Benefits, Cardio Respiratory Fitness, Brain Activity
Interventions
High-Intensity Interval Training
Behavioral
Lead sponsor
Colby-Sawyer College
Other
Eligibility
55 Years to 79 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
New London, New Hampshire
Conditions
Adolescents With Food Insecurity
Interventions
Increased Egg Consumption, Typical diet
Other
Lead sponsor
Texas Tech University
Other
Eligibility
13 Years to 19 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
2
States / cities
Lubbock, Texas
Conditions
Memory Impairment
Interventions
simultaneous aerobic exercise, sequential aerobic exercise, stretching and toning
Other
Lead sponsor
David Merrill, MD, PhD
Other
Eligibility
60 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Los Angeles, California
Completed Not applicable Interventional Accepts healthy volunteers

The Cognitive Ageing Nutrition and Neurogenesis (CANN) Trial

NCT02525198
Conditions
Mild Cognitive Impairment, Subjective Memory Impairment
Interventions
fatty acid/flavonoid blend, Placebo
Dietary Supplement
Lead sponsor
University of East Anglia
Other
Eligibility
55 Years and older
Enrollment
259 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Urbana, Illinois
Completed Not applicable Interventional Accepts healthy volunteers

Cognitive Benefits of Aerobic Exercise Across the Age Span

NCT01179958
Conditions
Cognitive Function
Interventions
aerobic training, stretching/toning
Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
20 Years to 68 Years
Enrollment
305 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2016
U.S. locations
1
States / cities
New York, New York
Recruiting Not applicable Interventional Accepts healthy volunteers

Trout Consumption in Young Children and Families and Brain Health

NCT06721468
Conditions
Cognitive Change, Well-Being, Psychological
Interventions
Trout, Child-centered nutrition phrases, Puzzle
Other
Lead sponsor
University of Idaho
Other
Eligibility
3 Years and older
Enrollment
99 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
2
States / cities
Moscow, Idaho • Pullman, Washington
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Emotional, Physical and Cognitive Benefits of Purposeful Green Space Activities on Seniors

NCT04913363
Conditions
Loneliness, Social Isolation, Mood, Well Aging, Physical Activity, Mobility Limitation
Interventions
Green space
Other
Lead sponsor
University of Virginia
Other
Eligibility
65 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Charlottesville, Virginia
Conditions
Heart Failure
Interventions
Not listed
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
50 Years to 85 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Akron, Ohio
Completed Phase 2 Interventional Accepts healthy volunteers

Thinking, Walking Outcomes by Type of Exercise

NCT01635348
Conditions
Gait Disorder, Sensorimotor, Cognitive Disorder
Interventions
motor skill gait exercise, aerobic gait intervention
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
65 Years and older
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Completed Not applicable Interventional Results available

Cognitive Benefits of Treating Sleep Apnea in Parkinson's Disease

NCT00492115
Conditions
Parkinson's Disease, Sleep Disordered Breathing
Interventions
Continuous positive airway pressure (CPAP), Placebo CPAP
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
50 Years and older
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2013
U.S. locations
1
States / cities
San Diego, California
Conditions
Cognitive Impairment, Mild, Dementia, Cardiovascular Diseases
Interventions
Atorvastatin 40 Mg Oral Tablet, Placebo oral tablet
Drug
Lead sponsor
Duke University
Other
Eligibility
75 Years and older
Enrollment
20,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
104
States / cities
Birmingham, Alabama • Tucson, Arizona • Little Rock, Arkansas + 70 more
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Treating Sleep Apnea on Cognition in Patients With Dementia

NCT00477828
Conditions
Dementia, Sleep Apnea
Interventions
Continuous positive airway pressure
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
50 Years to 85 Years
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2000 – 2006
U.S. locations
1
States / cities
San Diego, California
Conditions
Brain Injuries
Interventions
Cognitive Group Therapy
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2008
U.S. locations
1
States / cities
Rochester, Minnesota
Terminated Not applicable Interventional Accepts healthy volunteers

The Benefits of Naps on Cognitive, Emotional, and Motor Learning in Preschoolers

NCT03285880
Conditions
Sleep
Interventions
Napping
Behavioral
Lead sponsor
University of Massachusetts, Amherst
Other
Eligibility
33 Months to 60 Months
Enrollment
361 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
Amherst, Massachusetts
Conditions
Anxiety, Stress, Memory Deficits, Cortisol Overproduction
Interventions
Heights Smart Supplement
Dietary Supplement
Lead sponsor
Heights
Industry
Eligibility
21 Years to 70 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Santa Monica, California
Completed Not applicable Interventional Accepts healthy volunteers

Benefits of a Higher Protein, 'Egg-cellent' Breakfast in the Classroom

NCT03536676
Conditions
Breakfast, Obesity, Mood, Eating Behavior
Interventions
'Egg-cellent' Breakfast in the Classroom, Breakfast in the Classroom
Other
Lead sponsor
Purdue University
Other
Eligibility
10 Years to 16 Years
Enrollment
91 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Kansas City, Missouri
Conditions
Parkinson's Disease, Freezing of Gait, Cognitive Ability, General
Interventions
Droxidopa, sugar pill
Drug
Lead sponsor
Henry Ford Health System
Other
Eligibility
30 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
2
States / cities
Chicago, Illinois • West Bloomfield, Michigan
Conditions
MCI, Mild Cognitive Impairment, Alzheimer Disease, Dementia
Interventions
iPACES (interactive Physical and Cognitive Exercise System), PACE (Physical and Cognitive Exercise)
Device
Lead sponsor
iPACES LLC
Industry
Eligibility
50 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Clifton Park, New York