Independent directory Public ClinicalTrials.gov records United States
Clinical Trials Finder
Objective public record navigation
Search Results

Search by objective public record fields.

Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.

Clear filters
ClinicalTrials.gov public records Last synced Jun 25, 2026, 9:27 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Cognitive Disorder Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Personalized Lifestyle Intervention for Improving Functional Health Outcomes Using N-of-1 Tent-Umbrella-Bucket Design

NCT04005456
View directory record Official record
Conditions
Health, Subjective, Gastrointestinal Dysfunction, Cardiovascular Risk Factor, Autoimmune Diseases, Dental Diseases, Hormone Disturbance, Neurocognitive Dysfunction
Interventions
Supplements and/or medical foods, Behavioral change support program, Food plan
Dietary Supplement · Behavioral · Other
Lead sponsor
Metagenics, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
Gig Harbor, Washington
Source: ClinicalTrials.gov public record
Updated Oct 29, 2023 · Synced Jun 25, 2026, 9:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Arts Engagement on Physical Performance, Cognition, Social Isolation, and Self-Perception in Older Adults

NCT04281654
View directory record Official record
Conditions
Social Isolation, Mental Status Change, Cognitive Impairment, Physical Activity, Quality of Life, Self-Perception
Interventions
Active Social Conversation
Other
Lead sponsor
George Mason University
Other
Eligibility
65 Years to 100 Years
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Manassas, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 3, 2022 · Synced Jun 25, 2026, 9:27 PM EDT
Completed Phase 3 Interventional Results available

Preventing Cognitive Decline in African Americans With Mild Cognitive Impairment

NCT01299766
View directory record Official record
Conditions
Mild Cognitive Impairment (MCI)
Interventions
Behavioral Activation (BA), Supportive Therapy (ST)
Behavioral
Lead sponsor
Thomas Jefferson University
Other
Eligibility
65 Years and older
Enrollment
221 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 11, 2018 · Synced Jun 25, 2026, 9:27 PM EDT
Enrolling by invitation Not applicable Interventional

Extension to a Pivotal Study of Sensory Stimulation in Alzheimer's Disease (OLE Hope Study, CA-0015)

NCT06245031
View directory record Official record
Conditions
Alzheimer Disease, Cognitive Impairment, Mild Cognitive Impairment, Dementia, Mild, Dementia Moderate, Dementia Alzheimers, Dementia of Alzheimer Type, AD
Interventions
Sensory Stimulation System (GS120) - Active
Device
Lead sponsor
Cognito Therapeutics, Inc.
Industry
Eligibility
50 Years to 92 Years
Enrollment
402 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
53
States / cities
Phoenix, Arizona • Sun City, Arizona • Anaheim, California + 48 more
Source: ClinicalTrials.gov public record
Updated May 6, 2024 · Synced Jun 25, 2026, 9:27 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Development of Adaptive Deep Brain Stimulation for OCD (Phase 1a)

NCT03457675
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Activa PC+S DBS implant for OCD, One Month Blinded Discontinuation Period
Device · Other
Lead sponsor
Baylor College of Medicine
Other
Eligibility
21 Years to 70 Years
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2027
U.S. locations
3
States / cities
Pittsburgh, Pennsylvania • Providence, Rhode Island • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 26, 2026 · Synced Jun 25, 2026, 9:27 PM EDT
Completed Early Phase 1 Interventional

Pharmacologic and Clinical Testing of a D1 Agonist for Cognitive Enhancement in Neuropsychiatric Disorders

NCT01519557
View directory record Official record
Conditions
Schizophrenia, Schizoaffective Disorder
Interventions
DAR-100A, Placebo
Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 55 Years
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 3, 2015 · Synced Jun 25, 2026, 9:27 PM EDT
Terminated Phase 2 Interventional Results available

Feasibility Study of Duloxetine in the Treatment of Depression in Patients With Traumatic Brain Injury

NCT01223001
View directory record Official record
Conditions
Traumatic Brain Injury, Depression
Interventions
Duloxetine, Sugar pill
Drug
Lead sponsor
Rehabilitation Hospital of Indiana
Other
Eligibility
18 Years to 75 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1996 – 2011
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Dec 16, 2014 · Synced Jun 25, 2026, 9:27 PM EDT
Completed Phase 2 Interventional Results available

Depressed Mood Improvement Through Nicotine Dosing 2

NCT04433767
View directory record Official record
Conditions
Depressive Disorder
Interventions
Transdermal Nicotine patch
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
60 Years and older
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 5, 2023 · Synced Jun 25, 2026, 9:27 PM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Aging and Disease Course: Contributions to Lifespan Neurobiology of Schizophrenia

NCT04951700
View directory record Official record
Conditions
Schizophrenia, Aging, Disease Course, Biomarker, Neuroimaging, Cognitive Dysfunction
Interventions
Other
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 75 Years
Enrollment
194 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Aug 20, 2025 · Synced Jun 25, 2026, 9:27 PM EDT
Not listed Not applicable Interventional

TIMBER Psychotherapy and Ketamine Single Infusion in Chronic PTSD

NCT02766192
View directory record Official record
Conditions
PTSD
Interventions
Ketamine, TIMBER Psychotherapy, Placebo (normal saline)
Drug · Behavioral
Lead sponsor
The Cooper Health System
Other
Eligibility
21 Years to 60 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2013
U.S. locations
1
States / cities
Camden, New Jersey
Source: ClinicalTrials.gov public record
Updated May 8, 2016 · Synced Jun 25, 2026, 9:27 PM EDT
Recruiting Not applicable Interventional

Testing an Integrated PTSD and Weight Management Intervention: A Hybrid Type 1 Trial

NCT07010757
View directory record Official record
Conditions
PTSD, Obesity
Interventions
HARPP, control arm for HARPP trial
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
182 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Mar 17, 2026 · Synced Jun 25, 2026, 9:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

High Speed Circuit Training and Cognition

NCT04022707
View directory record Official record
Conditions
Educational Control, Resistance Training
Interventions
High-speed circuit resistance training, Educational control
Other
Lead sponsor
University of Miami
Other
Eligibility
60 Years to 85 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
2
States / cities
Coral Gables, Florida
Source: ClinicalTrials.gov public record
Updated May 17, 2020 · Synced Jun 25, 2026, 9:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

iTBS rTMS in Mild Cognitive Impairment

NCT05327257
View directory record Official record
Conditions
Mild Cognitive Impairment
Interventions
iTBS rTMS
Device
Lead sponsor
Maria I. Lapid, M.D.
Other
Eligibility
55 Years to 90 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 11, 2026 · Synced Jun 25, 2026, 9:27 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Genes, Exercise, Neurocognitive and Neurodegeneration: Community-Based Approach

NCT02614365
View directory record Official record
Conditions
Mild Cognitive Impairment
Interventions
Aerobic exercise, Stretch exercise
Behavioral
Lead sponsor
Howard University
Other
Eligibility
55 Years to 85 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2022
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Mar 1, 2021 · Synced Jun 25, 2026, 9:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Weight Loss and Cognitive Function in Adults

NCT03685305
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Hypocaloric diet with hunger reduction strategy, Hypocaloric diet without hunger reduction strategy
Behavioral
Lead sponsor
Virginia Polytechnic Institute and State University
Other
Eligibility
50 Years to 75 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Blacksburg, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 20, 2025 · Synced Jun 25, 2026, 9:27 PM EDT
Active, not recruiting Phase 2 Interventional

GENERATION HD2. A Study to Evaluate the Safety, Biomarkers, and Efficacy of Tominersen Compared With Placebo in Participants With Prodromal and Early Manifest Huntington's Disease

NCT05686551
View directory record Official record
Conditions
Huntington Disease
Interventions
Tominersen, Placebo
Drug
Lead sponsor
Hoffmann-La Roche
Industry
Eligibility
25 Years to 50 Years
Enrollment
301 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
18
States / cities
Birmingham, Alabama • Phoenix, Arizona • Sacramento, California + 15 more
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Jun 25, 2026, 9:27 PM EDT
Completed Not applicable Interventional

Reducing PTSD in Hospitalized Burn Patients

NCT02026037
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Brief Treatment for Acutely Burned Patients (BTBP)
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 20, 2017 · Synced Jun 25, 2026, 9:27 PM EDT
Completed Not applicable Interventional

Sleep Disordered Breathing and Its Impact on Neuro-cognitive Performance and Quality of Life in Parkinson Disease

NCT02034357
View directory record Official record
Conditions
Parkinson's Disease, Sleep Disordered Breathing, Sleep Obstructive Apnea
Interventions
Neurocognitive function, Sleep evaluations
Other
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
89 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Mar 23, 2016 · Synced Jun 25, 2026, 9:27 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Cognitive Effects of Aerobic Exercise for MCI Adults

NCT00220467
View directory record Official record
Conditions
Mild Cognitive Impairment
Interventions
Aerobic exercise
Behavioral
Lead sponsor
Seattle Institute for Biomedical and Clinical Research
Other
Eligibility
55 Years to 90 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2008
U.S. locations
2
States / cities
Seattle, Washington • Tacoma, Washington
Source: ClinicalTrials.gov public record
Updated Jul 29, 2008 · Synced Jun 25, 2026, 9:27 PM EDT
Completed Phase 3 Interventional

Telemental Health and Cognitive Processing Therapy for Female Veterans With Military-related PTSD

NCT02362477
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Cognitive Processing Therapy in-person, Cognitive Processing Therapy through videoteleconference
Behavioral
Lead sponsor
VA Pacific Islands Health Care System
Federal
Eligibility
18 Years and older · Female only
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Honolulu, Hawaii
Source: ClinicalTrials.gov public record
Updated Feb 12, 2015 · Synced Jun 25, 2026, 9:27 PM EDT
Completed No phase listed Observational

Quality Improvement PrecivityAD Clinician Survey (QUIP I)

NCT05477056
View directory record Official record
Conditions
Alzheimer Disease, Mild Cognitive Impairment, Dementia, Cognitive Decline
Interventions
PrecivityAD blood test
Other
Lead sponsor
C2N Diagnostics
Industry
Eligibility
60 Years and older
Enrollment
366 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 19, 2025 · Synced Jun 25, 2026, 9:27 PM EDT
Completed Phase 1 Interventional

Effectiveness of Cognitive Remediation Therapy in Improving Treatment Retention in People With Anorexia Nervosa

NCT00601822
View directory record Official record
Conditions
Anorexia Nervosa
Interventions
Cognitive remediation therapy (CRT), Cognitive behavioral therapy (CBT)
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Apr 9, 2012 · Synced Jun 25, 2026, 9:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Enhancing Spatial Navigation Using Non-Invasive Brain Stimulation

NCT01958437
View directory record Official record
Conditions
Mild Cognitive Impairment, Alzheimer's Disease
Interventions
Transcranial direct current stimulation (tDCS)
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
50 Years to 88 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
2
States / cities
Decatur, Georgia • Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 30, 2018 · Synced Jun 25, 2026, 9:27 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Cardiac-Control Affecting Learning Through Mindfulness (CALM)

NCT06410157
View directory record Official record
Conditions
Age-related Cognitive Decline, Alzheimer Disease
Interventions
Daily practice
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
50 Years to 70 Years
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 12, 2026 · Synced Jun 25, 2026, 9:27 PM EDT