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ClinicalTrials.gov public records Last synced Oct 29, 2026, 5:00 PM EDT

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Showing 913–936 of 4,396 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Cognitive Disorders Clear all
Recruiting Phase 1 Interventional Accepts healthy volunteers

TREAD: Time Restricted Eating Intervention for Alzheimer's Disease

NCT06548191
View directory record Official record
Conditions
Mild Cognitive Impairment, Alzheimer Disease, Alzheimer's Disease
Interventions
Time-restricted eating
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
60 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated May 26, 2026 · Synced Oct 29, 2026, 5:00 PM EDT
Active, not recruiting Not applicable Interventional

Cognitive Enhancement Intervention for Creating a Healthy L.I.F.E (Lifestyle Interventions for Epilepsy)

NCT05954182
View directory record Official record
Conditions
Epilepsy
Interventions
Cognitive Intervention
Behavioral
Lead sponsor
Kayela Arrotta
Other
Eligibility
18 Years to 60 Years
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Oct 29, 2026, 5:00 PM EDT
Completed Phase 1 Interventional

Traumatic Brain Injury Peripheral Nerve Study

NCT01588691
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Eon-mini IPG (implantable pulse generator)
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years to 65 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Poway, California
Source: ClinicalTrials.gov public record
Updated Feb 4, 2019 · Synced Oct 29, 2026, 5:00 PM EDT
Completed Not applicable Interventional

Mild Cognitive Impairment, Buddy Supported Exercise/ My Buddy Study

NCT01561820
View directory record Official record
Conditions
Mild Cognitive Impairment, Cognitive Disorders
Interventions
5-month aerobic exercise intervention
Behavioral
Lead sponsor
Wake Forest University
Other
Eligibility
60 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 26, 2019 · Synced Oct 29, 2026, 5:00 PM EDT
Completed No phase listed Observational

Project AWARE 2.0 to Improve Awareness, Willingness and Ability for Research and Enrollment in Clinical Research

NCT06343220
View directory record Official record
Conditions
Huntington Disease
Interventions
Not listed
Lead sponsor
Huntington Study Group
Network
Eligibility
18 Years and older
Enrollment
131 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Dec 23, 2025 · Synced Oct 29, 2026, 5:00 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Daily Consumption of Eggs on Cognitive Function in the Elderly

NCT01621646
View directory record Official record
Conditions
Mild Cognitive Impairment
Interventions
eggs or egg whites
Other
Lead sponsor
Tufts University
Other
Eligibility
50 Years and older
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 1, 2017 · Synced Oct 29, 2026, 5:00 PM EDT
Completed Not applicable Interventional

Neurofeedback Technology (GZNT) for Persistent Post-Concussive Symptoms in Soldiers

NCT02509689
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Global Z-Score Neurofeedback Training
Behavioral
Lead sponsor
The Defense and Veterans Brain Injury Center
Federal
Eligibility
18 Years to 50 Years
Enrollment
172 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2022
U.S. locations
1
States / cities
Fort Carson, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 4, 2022 · Synced Oct 29, 2026, 5:00 PM EDT
Recruiting No phase listed Observational

Alzheimer's National Registry for Treatment and Diagnostics(ALZ-NET)

NCT06170268
View directory record Official record
Conditions
Alzheimer Disease
Interventions
Routine Care Documentation
Other
Lead sponsor
Alzheimer's Disease and Related Disorders Association, Inc
Other
Eligibility
18 Years and older
Enrollment
20,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2032
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 14, 2023 · Synced Oct 29, 2026, 5:00 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Brain Energy and Cognition

NCT01603550
View directory record Official record
Conditions
Energy Restriction, Sleep Deprivation
Interventions
Sleep Deprivation, Energy Restriction
Other
Lead sponsor
United States Army Research Institute of Environmental Medicine
Federal
Eligibility
18 Years to 39 Years
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Natick, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 6, 2016 · Synced Oct 29, 2026, 5:00 PM EDT
Completed Not applicable Interventional

Cognitive Remediation Therapy for Adolescents With Anorexia Nervosa

NCT02883413
View directory record Official record
Conditions
Anorexia Nervosa
Interventions
CRT + Teach the Parent, CRT + Contact Control
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
12 Years to 18 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 6, 2019 · Synced Oct 29, 2026, 5:00 PM EDT
Recruiting Phase 1Phase 2 Interventional

Safety and Tolerability Study of Human Neural Stem Cells for Huntington's Disease

NCT07451613
View directory record Official record
Conditions
Huntington Disease
Interventions
hNSC-01
Biological
Lead sponsor
Leslie Thompson
Other
Eligibility
18 Years to 65 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Oct 29, 2026, 5:00 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Scalable Model for Promoting Functioning and Well-Being Among Older Adults With Mild Cognitive Impairment Via Meaningful Social Interactions: Project SPEAK!

NCT04717479
View directory record Official record
Conditions
Mild Cognitive Impairment
Interventions
Intervention (videoconferencing)
Other
Lead sponsor
University of Michigan
Other
Eligibility
55 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 20, 2023 · Synced Oct 29, 2026, 5:00 PM EDT
Withdrawn Phase 2 Interventional

Safety Study of Sargramostim in Treating Patients With Mild Cognitive Impairment Due to Alzheimer's Disease

NCT02667496
View directory record Official record
Conditions
Dementia Alzheimer's Type
Interventions
Sargramostim GZ402664, Placebo, Florbetapir F18
Drug
Lead sponsor
Sanofi
Industry
Eligibility
40 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 7, 2017 · Synced Oct 29, 2026, 5:00 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Circle Game Collaborative--Freddie the Frog

NCT05522946
View directory record Official record
Conditions
Cognitive Impairment, Physical Disability
Interventions
Gameplay between parent and child or adolescent with or without a disability
Other
Lead sponsor
Ohio State University
Other
Eligibility
5 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 15, 2023 · Synced Oct 29, 2026, 5:00 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Personalized, Augmented Cognitive Training (PACT) for Service Members and Veterans with a History of TBI

NCT04560946
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Personalized Augmented Cognitive Training (PACT), Enhanced Treatment As Usual
Behavioral
Lead sponsor
Veterans Medical Research Foundation
Other
Eligibility
18 Years to 55 Years
Enrollment
107 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
2
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Nov 21, 2024 · Synced Oct 29, 2026, 5:00 PM EDT
Completed Not applicable Interventional Results available

CPT-L to Improve Outcomes for Individuals With HIV and PTSD

NCT05275842
View directory record Official record
Conditions
PTSD, Hiv
Interventions
Cognitive Processing Therapy- Lifesteps (CPT-L), Lifesteps
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Mar 4, 2025 · Synced Oct 29, 2026, 5:00 PM EDT
Completed Phase 4 Interventional Results available

Mirabegron in Parkinson Disease and Impaired Cognition

NCT02536976
View directory record Official record
Conditions
Parkinson Disease, Overactive Bladder, Impaired Cognition
Interventions
mirabegron, Placebo
Drug
Lead sponsor
HealthPartners Institute
Other
Eligibility
25 Years to 80 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Golden Valley, Minnesota
Source: ClinicalTrials.gov public record
Updated May 8, 2019 · Synced Oct 29, 2026, 5:00 PM EDT
Completed No phase listed Observational

Neurological Effects of Chemotherapy and Radiation Therapy in Patients With Colon Cancer

NCT00410618
View directory record Official record
Conditions
Cognitive/Functional Effects, Colorectal Cancer, Long-term Effects Secondary to Cancer Therapy in Adults
Interventions
cognitive assessment, magnetic resonance imaging, management of therapy complications
Procedure
Lead sponsor
University of Arizona
Other
Eligibility
Not listed
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2006
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Jul 6, 2018 · Synced Oct 29, 2026, 5:00 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Modulating ApoE Signalling to Reduce Brain Inflammation, deLirium and postopErative Cognitive Dysfunction

NCT03802396
View directory record Official record
Conditions
Postoperative Delirium, Postoperative Cognitive Dysfunction
Interventions
CN-105, Placebo
Drug
Lead sponsor
Miles Berger, MD PhD
Other
Eligibility
60 Years and older
Enrollment
203 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 16, 2024 · Synced Oct 29, 2026, 5:00 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Efficacy of a Computerized Cognitive Behavioral Treatment for Insomnia: Increasing Access to Insomnia Treatment to Decrease Suicide Risk

NCT03366870
View directory record Official record
Conditions
Insomnia, Physical Health Functioning, Mental Health Functioning
Interventions
Computerized Cognitive Behavioral Therapy for Insomnia, Sleep Education
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 55 Years
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 1, 2020 · Synced Oct 29, 2026, 5:00 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Computer-Based Training in Cognitive Behavior Therapy

NCT00350610
View directory record Official record
Conditions
Cocaine Abuse
Interventions
Treatment as usual (TAU), CBT for CBT
Other · Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2012
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 29, 2013 · Synced Oct 29, 2026, 5:00 PM EDT
Completed No phase listed Observational

Magnetic Resonance Imaging to Detect Brain Damage in Patients With Multiple Sclerosis

NCT00393588
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years to 60 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Oct 29, 2026, 5:00 PM EDT
Completed No phase listed Observational

Neurobehavioral Model of HIV in Injection Drug Users

NCT00198861
View directory record Official record
Conditions
Drug Abuse, HIV Infections
Interventions
Injection and Non-Injection Drug Users
Other
Lead sponsor
The City College of New York
Other
Eligibility
15 Years to 50 Years
Enrollment
836 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2016
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 2, 2016 · Synced Oct 29, 2026, 5:00 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Study of the Psychological Development of Children of Parents With and Without Affective Disorders

NCT00001170
View directory record Official record
Conditions
Bipolar Disorder, Involutional Depression, Mood Disorder
Interventions
Not listed
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
Not listed
Enrollment
1,045 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1979 – 2005
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 29, 2026, 5:00 PM EDT