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ClinicalTrials.gov public records Last synced Oct 19, 2026, 4:17 PM EDT

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Showing 457–480 of 1,062 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Cognitive Functioning Clear all
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Effects of Methylene Blue in Healthy Aging, Mild Cognitive Impairment and Alzheimer's Disease

NCT02380573
View directory record Official record
Conditions
Mild Cognitive Impairment, MCI, Aging, Alzheimer's Disease, AD
Interventions
Methylene Blue, FD&C Blue # 2, Phenazopyridine hydrochloride
Drug
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
45 Years to 89 Years
Enrollment
117 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2023
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 19, 2026, 4:17 PM EDT
Active, not recruiting Early Phase 1 Interventional

Modafinil and Cognitive Function in POTS

NCT01988883
View directory record Official record
Conditions
Postural Tachycardia Syndrome
Interventions
Placebo, Modafinil, Propranolol
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 60 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2026
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 15, 2026 · Synced Oct 19, 2026, 4:17 PM EDT
Completed Early Phase 1 Interventional

Nitrate Supplementation and Cerebrovascular and Cognitive Function in Metabolic Syndrome

NCT05532423
View directory record Official record
Conditions
Metabolic Syndrome
Interventions
Beetroot Juice - Active, beetroot juice - Placebo
Drug
Lead sponsor
Penn State University
Other
Eligibility
55 Years to 75 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 6, 2025 · Synced Oct 19, 2026, 4:17 PM EDT
Completed Not applicable Interventional Results available

Restoration of Cognitive Function With TDCS and Training in Serious Mental Illness

NCT03208036
View directory record Official record
Conditions
Schizophrenia, Bipolar Disorder, Schizo Affective Disorder
Interventions
TDCS, Sham Stimulation, Cognitive Remediation, Bridging Group
Device · Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 21, 2022 · Synced Oct 19, 2026, 4:17 PM EDT
Completed Phase 3 Interventional Results available

Prasterone (Dehydroepiandrosterone) in Treating Postmenopausal Cancer Survivors With Vaginal Symptoms

NCT01376349
View directory record Official record
Conditions
Breast Cancer, Gynecologic Cancer
Interventions
prasterone, placebo
Drug · Other
Lead sponsor
Alliance for Clinical Trials in Oncology
Other
Eligibility
18 Years and older · Female only
Enrollment
464 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
280
States / cities
Scottsdale, Arizona • Aurora, Colorado • Boulder, Colorado + 185 more
Source: ClinicalTrials.gov public record
Updated Feb 7, 2019 · Synced Oct 19, 2026, 4:17 PM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

Effects of a Breakfast and Snack on Cognitive Function in Preadolescents

NCT01592487
View directory record Official record
Conditions
Brain Function
Interventions
Not listed
Lead sponsor
University of Arkansas
Other
Eligibility
9 Years to 11 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Feb 12, 2014 · Synced Oct 19, 2026, 4:17 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Ovarian Hormone Suppression on Vascular and Cognitive Function

NCT03112226
View directory record Official record
Conditions
Cognitive Impairment, Estrogen Deficiency, Menopause, Endothelial Dysfunction, Vascular Stiffness
Interventions
GnRHant + E2, GnRHant + Placebo
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
2
States / cities
Aurora, Colorado • Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 7, 2021 · Synced Oct 19, 2026, 4:17 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Diet Composition on Performance, Expenditure, Blood Lipids, and Appetite Hormones in Highly Trained Cyclists

NCT04097171
View directory record Official record
Conditions
Endurance Cycling Performance
Interventions
Diet
Other
Lead sponsor
Texas Christian University
Other
Eligibility
18 Years to 65 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Oct 5, 2021 · Synced Oct 19, 2026, 4:17 PM EDT
Completed No phase listed Observational

Neurocognitive Functioning in Patients With Newly Diagnosed Upper Aerodigestive Tract Cancer Receiving Treatment at Henry-Joyce Cancer Clinic

NCT00533884
View directory record Official record
Conditions
Neurocognitive Impairment, Delirium, Esophageal Cancer, Head and Neck Cancer, Lung Cancer
Interventions
Assessment of therapy complications, Neurocognitive assessment, Quality-of-life assessment
Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
21 Years and older
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2013
U.S. locations
4
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 7, 2017 · Synced Oct 19, 2026, 4:17 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Efficacy of a Microalgae Extract PhaeoSOL Combined With Natural Stimulant on Cognitive Function and Gaming Performance of Video Gamers

NCT04851899
View directory record Official record
Conditions
Cognitive Function, Video Gamers
Interventions
Phaeosol low dose, Phaeosol high dose, Placebo
Dietary Supplement
Lead sponsor
Microphyt
Industry
Eligibility
18 Years to 40 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
College Station, Texas
Source: ClinicalTrials.gov public record
Updated Sep 23, 2022 · Synced Oct 19, 2026, 4:17 PM EDT
Completed Not applicable Interventional Results available

Training in Goal-directed Attention Regulation for Individuals With Brain Injury

NCT01035606
View directory record Official record
Conditions
Brain Injury
Interventions
training in goal-directed attention regulation, brain health education, computer-assisted training in goal-directed attention regulation
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 75 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2017
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Oct 20, 2017 · Synced Oct 19, 2026, 4:17 PM EDT
Not listed Not applicable Interventional

The Effects of Specialty Coffee on Cognitive Function in People With Type 2 Diabetes

NCT05709847
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Coffee
Other
Lead sponsor
University of Reading
Other
Eligibility
55 Years to 70 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Feb 2, 2023 · Synced Oct 19, 2026, 4:17 PM EDT
Completed No phase listed Observational

Cognitive Function After Treatment of Primary CNS Malignancy

NCT03055364
View directory record Official record
Conditions
CNS Malignancy
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
4 Years and older
Enrollment
129 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 10, 2024 · Synced Oct 19, 2026, 4:17 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Playing Cognitive Games For Older Adults With Insomnia

NCT04282642
View directory record Official record
Conditions
Insomnia
Interventions
Cognitive Training, WLC (Waitlist Control)
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
60 Years and older
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Aug 30, 2023 · Synced Oct 19, 2026, 4:17 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

IMProving Executive Function Study

NCT03187353
View directory record Official record
Conditions
Cognitive Impairment, RRSO
Interventions
Lisdexamfetamine, Placebo oral capsule
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
35 Years to 58 Years · Female only
Enrollment
69 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 18, 2023 · Synced Oct 19, 2026, 4:17 PM EDT
Completed Not applicable Interventional

Treatment of Depression in Mothers in Home Visitation

NCT01221701
View directory record Official record
Conditions
Depressive Disorder in Mothers
Interventions
In-Home Cognitive Behavioral Psychology
Behavioral
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
16 Years to 45 Years · Female only
Enrollment
93 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2013
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 18, 2013 · Synced Oct 19, 2026, 4:17 PM EDT
Completed Not applicable Interventional

Exercise in Adults with Post-Acute Sequelae of SARS-CoV-2 (COVID-19) Infection Study

NCT05218174
View directory record Official record
Conditions
COVID-19
Interventions
Exercise Prescription
Other
Lead sponsor
Baylor Research Institute
Other
Eligibility
18 Years to 65 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Frisco, Texas
Source: ClinicalTrials.gov public record
Updated Jan 22, 2025 · Synced Oct 19, 2026, 4:17 PM EDT
Completed Not applicable Interventional

Case Studies: Promoting Strategy Use in Functional Activities

NCT04363645
View directory record Official record
Conditions
Cognitive Impairment, Executive Dysfunction, Acquired Brain Injury
Interventions
Multicontext (MC) approach
Other
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 80 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 27, 2020 · Synced Oct 19, 2026, 4:17 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effects of Transcranial Electrical Stimulation on Task Performance in Healthy Adults

NCT06995560
View directory record Official record
Conditions
Healthy, Brain Stimulation, Transcranial Direct Current Stimulation (tDCS), Cognition, Psychomotor Performance, Neurophysiology
Interventions
Active Transcranial Electrical Stimulation, Sham Transcranial Electrical Stimulation
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
25 Years to 55 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 15, 2026 · Synced Oct 19, 2026, 4:17 PM EDT
Completed Not applicable Interventional

Modafinil in Treating Fatigue and Behavioral Change in Patients With Primary Brain Cancer

NCT00052286
View directory record Official record
Conditions
Brain and Central Nervous System Tumors, Cognitive/Functional Effects, Fatigue
Interventions
modafinil
Drug
Lead sponsor
Jonsson Comprehensive Cancer Center
Other
Eligibility
21 Years to 65 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2010
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 3, 2020 · Synced Oct 19, 2026, 4:17 PM EDT
Completed Not applicable Interventional

Associations of Cognition, Fitness, and Body Composition Among Ethnic Minority Youth

NCT03342924
View directory record Official record
Conditions
Obesity, Physical Activity, Cognitive Function 1, Social
Interventions
Flanker Test and physical fitness test
Other
Lead sponsor
University of Miami
Other
Eligibility
8 Years to 12 Years
Enrollment
212 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 17, 2017 · Synced Oct 19, 2026, 4:17 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Brain Ketone Metabolism in Type 1 Diabetes

NCT02471040
View directory record Official record
Conditions
Type 1 Diabetes, Hypoglycemia
Interventions
Beta-hydroxybutyrate, Normal Saline
Drug · Other
Lead sponsor
Yale University
Other
Eligibility
18 Years to 65 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2022
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 27, 2023 · Synced Oct 19, 2026, 4:17 PM EDT
Completed Phase 1 Interventional

Training Executive, Attention and Motor Skills (TEAMS): Preliminary Studies

NCT01073176
View directory record Official record
Conditions
Attention Deficit Hyperactivity Disorder
Interventions
TEAMS (Training Attention Executive and Motor Skills)
Other
Lead sponsor
Queens College, The City University of New York
Other
Eligibility
4 Years to 5 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Flushing, New York
Source: ClinicalTrials.gov public record
Updated Sep 14, 2011 · Synced Oct 19, 2026, 4:17 PM EDT
Terminated Not applicable Interventional

Dental Carotid Cognitive Study

NCT03755362
View directory record Official record
Conditions
Carotid Stenosis, Mild Cognitive Impairment, Periodontitis
Interventions
Standard Treatment, Intensive Treatment
Procedure
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
60 Years to 100 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 18, 2026 · Synced Oct 19, 2026, 4:17 PM EDT