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ClinicalTrials.gov public records Last synced Oct 20, 2026, 2:17 PM EDT

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Showing 913–936 of 1,065 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Cognitive Functioning Clear all
Completed No phase listed Observational Results available

Asymptomatic Carotid Stenosis: Cognitive Function and Plaque Correlates

NCT01353196
View directory record Official record
Conditions
Cognitive Manifestations
Interventions
Not listed
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2018
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 24, 2019 · Synced Oct 20, 2026, 2:17 PM EDT
Completed Not applicable Interventional Results available

Physical and Cognitive Function - Look AHEAD Ancillary Study

NCT01410097
View directory record Official record
Conditions
Diabetes, Weight Loss, Physical Function, Cognitive Function
Interventions
Lifestyle intervention, Diabetes Support Education
Behavioral
Lead sponsor
Wake Forest University
Other
Eligibility
45 Years to 74 Years
Enrollment
1,089 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
4
States / cities
Aurora, Colorado • Baton Rouge, Louisiana • Pittsburgh, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 10, 2018 · Synced Oct 20, 2026, 2:17 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Alternative Therapies for Improving Motor Impairment, Fall-risk and Overall Physical Function

NCT03758846
View directory record Official record
Conditions
Chronic Stroke, Healthy Aging
Interventions
Cognitive-motor exergaming, Conventional balance Training, Dance Therapy for Stroke, Dance Therapy for Older adults, Home education for Older adults
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years to 90 Years
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 8, 2019 · Synced Oct 20, 2026, 2:17 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

ELITE: Early Versus Late Intervention Trial With Estradiol

NCT00114517
View directory record Official record
Conditions
Atherosclerosis
Interventions
17B-estradiol, Placebo
Drug · Other
Lead sponsor
University of Southern California
Other
Eligibility
Female only
Enrollment
643 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2013
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 18, 2023 · Synced Oct 20, 2026, 2:17 PM EDT
Completed Early Phase 1 Interventional Results available

Progesterone for Cannabis Withdrawal

NCT03430050
View directory record Official record
Conditions
Cannabis Use Disorder, Cannabis Withdrawal
Interventions
Progesterone, Placebo
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated May 22, 2019 · Synced Oct 20, 2026, 2:17 PM EDT
Completed Phase 2 Interventional

Effects Of GW679769 On Sleep Onset And Maintenance,And Next Day Functioning In The Elderly And Non-elderly With Primary Insomnia

NCT00280436
View directory record Official record
Conditions
Sleep Initiation and Maintenance Disorders, Insomnia
Interventions
GW679769
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years and older
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
26
States / cities
Phoenix, Arizona • Tucson, Arizona • Anaheim, California + 21 more
Source: ClinicalTrials.gov public record
Updated Apr 16, 2015 · Synced Oct 20, 2026, 2:17 PM EDT
Completed Not applicable Interventional

Assessment of Cognitive Functioning Before and After Treatment With Duloxetine

NCT00933439
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Duloxetine
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 45 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Aug 13, 2013 · Synced Oct 20, 2026, 2:17 PM EDT
Completed Not applicable Interventional

A Case Formulation Approach to Cognitive Processing Therapy

NCT04407767
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Case Formulation plus Cognitive Processing Therapy, Cognitive Processing Therapy
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
179 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
8
States / cities
Phoenix, Arizona • Honolulu, Hawaii • New Orleans, Louisiana + 5 more
Source: ClinicalTrials.gov public record
Updated Mar 27, 2026 · Synced Oct 20, 2026, 2:17 PM EDT
Withdrawn Phase 4 Interventional

How Lidocaine Affects Outcomes In Orthopedic Surgery Patients

NCT01179100
View directory record Official record
Conditions
General Anesthesia, Surgeries Requiring A Minimum One Day Hospitalization, Elderly
Interventions
Lidocaine
Drug
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
65 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 7, 2015 · Synced Oct 20, 2026, 2:17 PM EDT
Withdrawn No phase listed Observational

Imaging of Brain Structural/Functional Connectivity and Amyloid and Tau Lesions in APOE4 Carriers.

NCT03816228
View directory record Official record
Conditions
Alzheimer Disease
Interventions
F 18 T807 Flortaucipir
Drug
Lead sponsor
Tammie L. S. Benzinger, MD, PhD
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 13, 2024 · Synced Oct 20, 2026, 2:17 PM EDT
Completed Not applicable Interventional

A Study of Decreased Mental Function Associated With HIV

NCT00027040
View directory record Official record
Conditions
Cognitive Disorders, HIV Infections
Interventions
Selegiline hydrochloride
Drug
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 2005
U.S. locations
12
States / cities
Los Angeles, California • San Diego, California • Stanford, California + 6 more
Source: ClinicalTrials.gov public record
Updated Jan 16, 2015 · Synced Oct 20, 2026, 2:17 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Ultrasound for Healthy Aging

NCT07168525
View directory record Official record
Conditions
Aging
Interventions
Ultrasound spa, Sham ultrasound spa
Device · Other
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
70 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Nov 17, 2025 · Synced Oct 20, 2026, 2:17 PM EDT
Active, not recruiting Not applicable Interventional

Partnered Dance Aerobic Exercise as a Neuroprotective, Motor and Cognitive Intervention in Parkinson's Disease

NCT04122690
View directory record Official record
Conditions
Parkinson's Disease, Exercise Therapy, Cognition
Interventions
PDAE, WAE
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
40 Years to 89 Years
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Decatur, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 13, 2026 · Synced Oct 20, 2026, 2:17 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Brain Energy and Cognition

NCT01603550
View directory record Official record
Conditions
Energy Restriction, Sleep Deprivation
Interventions
Sleep Deprivation, Energy Restriction
Other
Lead sponsor
United States Army Research Institute of Environmental Medicine
Federal
Eligibility
18 Years to 39 Years
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Natick, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 6, 2016 · Synced Oct 20, 2026, 2:17 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Cognitive Benefits of Aerobic Exercise Across the Age Span

NCT01179958
View directory record Official record
Conditions
Cognitive Function
Interventions
aerobic training, stretching/toning
Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
20 Years to 68 Years
Enrollment
305 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 17, 2018 · Synced Oct 20, 2026, 2:17 PM EDT
Completed No phase listed Observational

Cystic Fibrosis and Cognitive Function

NCT03820349
View directory record Official record
Conditions
Cystic Fibrosis
Interventions
Not listed
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 2, 2021 · Synced Oct 20, 2026, 2:17 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Benefits of a Higher Protein, 'Egg-cellent' Breakfast in the Classroom

NCT03536676
View directory record Official record
Conditions
Breakfast, Obesity, Mood, Eating Behavior
Interventions
'Egg-cellent' Breakfast in the Classroom, Breakfast in the Classroom
Other
Lead sponsor
Purdue University
Other
Eligibility
10 Years to 16 Years
Enrollment
91 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 10, 2022 · Synced Oct 20, 2026, 2:17 PM EDT
Withdrawn Phase 1 Interventional

Enhancing Processing Speed and Executive Functioning in Depressed Older Adults With Computerized Cognitive Training

NCT04836533
View directory record Official record
Conditions
Depression in Old Age, Depression
Interventions
Experimental: Computerized Cognitive Training, Experimental: Open-label antidepressant treatment, Active Comparator: Solitaire Training, Placebo Comparator: Placebo-controlled antidepressant treatment
Other · Drug
Lead sponsor
Queens College, The City University of New York
Other
Eligibility
50 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 28, 2023 · Synced Oct 20, 2026, 2:17 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Impact of Twin Hearts Meditation on Mood, Cognitive Functioning, and EEG Dynamics

NCT07005830
View directory record Official record
Conditions
Positive Mood States, Negative Mood States, Cognitive Processing Speed, Cognitive Flexibility
Interventions
Twin Hearts Meditation
Behavioral
Lead sponsor
NeuroMeditation Institute
Other
Eligibility
18 Years to 75 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Jun 5, 2025 · Synced Oct 20, 2026, 2:17 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Effect of Sleep Deprivation on Cognitive Function Among Cardiology Fellows

NCT05513339
View directory record Official record
Conditions
Wellness, Burnout, Sleep Deprivation, Executive Function
Interventions
WHOOP strap 4.0
Device
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years to 99 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 24, 2022 · Synced Oct 20, 2026, 2:17 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of Synaquell on Brain Function

NCT05041192
View directory record Official record
Conditions
Healthy
Interventions
Synaquell, Placebo
Dietary Supplement
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 21 Years · Male only
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 29, 2022 · Synced Oct 20, 2026, 2:17 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Investigating the Effects of Beef Consumption on Cognitive and Brain Health

NCT06690892
View directory record Official record
Conditions
Dietary Intervention, Dietary Proteins, Dietary Assessment, Cognitive Ability, General
Interventions
Ready-to-eat beef in frozen, 5-oz packages, Ready-to-eat beef in frozen, 1-oz packages
Dietary Supplement
Lead sponsor
University of Nebraska Lincoln
Other
Eligibility
19 Years to 24 Years
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Lincoln, Nebraska
Source: ClinicalTrials.gov public record
Updated May 29, 2026 · Synced Oct 20, 2026, 2:17 PM EDT
Not listed Phase 4 Interventional

Transcranial Magnetic Stimulation for Apathy in Mild Cognitive Impairment:Pilot Study

NCT02190019
View directory record Official record
Conditions
Apathy, Mild Cognitive Impairment
Interventions
Neurostar repetitive transcranial magnetic stimulator
Device
Lead sponsor
Central Arkansas Veterans Healthcare System
Federal
Eligibility
55 Years to 91 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Feb 10, 2016 · Synced Oct 20, 2026, 2:17 PM EDT
Completed Not applicable Interventional

Examining the Effects of (MiM) Treatment on Emotional and Cognitive Functioning of Residents in Long-term Care

NCT02219620
View directory record Official record
Conditions
Emotion, Impaired Cognition
Interventions
Music, Imagery, Movement, Social Control
Behavioral
Lead sponsor
George Mason University
Other
Eligibility
Not listed
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Manassas, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 21, 2016 · Synced Oct 20, 2026, 2:17 PM EDT