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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Cold Symptoms Clear all
Not listed Not applicable Interventional Accepts healthy volunteers

A Clinical Study to Determine if Beta Glucan Reduces the Incidence, Duration or Severity of URTIs Among Skiers

NCT05917015
View directory record Official record
Conditions
Upper Respiratory Tract Infections, Mental Stress
Interventions
Treatment, Placebo
Dietary Supplement · Other
Lead sponsor
USANA Health Sciences
Industry
Eligibility
18 Years to 30 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Park City, Utah
Source: ClinicalTrials.gov public record
Updated Jun 22, 2023 · Synced Sep 22, 2026, 4:00 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Does the Cap Increase the Finding of Polyps When Water Exchange Colonoscopy is Used

NCT03566615
View directory record Official record
Conditions
Colonoscopy, Polyp of Colon
Interventions
CAP-straight, CAP-daisy, water
Device · Other
Lead sponsor
VA Greater Los Angeles Healthcare System
Federal
Eligibility
50 Years to 75 Years
Enrollment
1,630 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
2
States / cities
Mather, California • Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Oct 5, 2022 · Synced Sep 22, 2026, 4:00 AM EDT
Completed Phase 1 Interventional

Study of the Treatment of Experimental Pain in Opioid Dependent Persons on Methadone or Buprenorphine Maintenance

NCT01642030
View directory record Official record
Conditions
Opioid Dependence, Pain, Addiction
Interventions
Placebo, Hydromorphone, Buprenorphine
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 55 Years
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 10, 2017 · Synced Sep 22, 2026, 4:00 AM EDT
Withdrawn Phase 1Phase 2 Interventional

A Pilot Study of XOMA 052 in Familial Cold Autoinflammatory Syndrome / Muckle-Wells Syndrome and Behcet's Disease

NCT01211977
View directory record Official record
Conditions
Muckle Wells Syndrome, Autoinflammatory, Behcet's Disease
Interventions
XOMA 052
Drug
Lead sponsor
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
NIH
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Sep 22, 2026, 4:00 AM EDT
Completed Phase 2 Interventional

Non-Pharmacologic Therapy for Neurocardiogenic Syncope

NCT00096902
View directory record Official record
Conditions
Syncope
Interventions
Tilt table test
Procedure
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Sep 22, 2026, 4:00 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Compare Ultrasound Assisted Cold Therapy and Lidocaine Injection to Treat Morton's Neuroma

NCT02838758
View directory record Official record
Conditions
Intermetatarsal Neuroma
Interventions
Cryoablation, Lidocaine, Saline
Device · Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 80 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 5, 2018 · Synced Sep 22, 2026, 4:00 AM EDT
Terminated Phase 4 Interventional Results available

Acute Cough Study In Children

NCT01257542
View directory record Official record
Conditions
Common Cold, Infections, Upper Respiratory Tract
Interventions
Dextromethorphan, Placebo
Drug
Lead sponsor
Pfizer
Industry
Eligibility
6 Years to 11 Years
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
4
States / cities
Pinellas Park, Florida • Indianapolis, Indiana • Gresham, Oregon + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 19, 2012 · Synced Sep 22, 2026, 4:00 AM EDT
Completed No phase listed Observational

Diagnosing Respiratory Disease in Children Using Cough Sounds

NCT02973282
View directory record Official record
Conditions
Pneumonia, Bronchiolitis, Asthma, Croup, Upper Respiratory Tract Infection, Lower Respiratory Tract Infection, Reactive Airway Disease
Interventions
Recording of Infants and Children's Cough Sounds
Other
Lead sponsor
ResApp Health Limited
Industry
Eligibility
29 Days to 12 Years
Enrollment
1,245 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
3
States / cities
Boston, Massachusetts • Cleveland, Ohio • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 4, 2018 · Synced Sep 22, 2026, 4:00 AM EDT
Terminated Phase 4 Interventional Results available

Motorized Continuous Cold Therapy Versus Standard Post-op Icing Protocol for Two Foot and Ankle Procedures

NCT00950183
View directory record Official record
Conditions
Narcotic Consumption, Pain, Wound Healing, Patient Satisfaction
Interventions
Iceman® Cold Therapy unit (djOrtho), Ice
Device · Other
Lead sponsor
OrthoCarolina Research Institute, Inc.
Other
Eligibility
Not listed
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 21, 2016 · Synced Sep 22, 2026, 4:00 AM EDT
Active, not recruiting Not applicable Interventional

Cold Snare Endoscopic Mucosal Resection Trial

NCT03865537
View directory record Official record
Conditions
Colonic Polyp, Colonoscopy, Complication, Recurrence
Interventions
Cold snare EMR, Hot snare EMR, Eleview injection, Placebo injection
Procedure
Lead sponsor
White River Junction Veterans Affairs Medical Center
Federal
Eligibility
18 Years and older
Enrollment
990 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
White River Junction, Vermont
Source: ClinicalTrials.gov public record
Updated Jun 20, 2024 · Synced Sep 22, 2026, 4:00 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Influence of Genetics in Pain Sensitivity

NCT00001956
View directory record Official record
Conditions
Healthy, Hyperalgesia, Pain
Interventions
Blood draw, Oral surgery, Tissue biopsy
Procedure
Lead sponsor
National Institute of Dental and Craniofacial Research (NIDCR)
NIH
Eligibility
Not listed
Enrollment
800 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2000 – 2005
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 29, 2006 · Synced Sep 22, 2026, 4:00 AM EDT
Active, not recruiting Phase 2 Interventional

Study of BLU-808 in Chronic Inducible Urticaria (CIndU) and Chronic Spontaneous Urticaria (CSU)

NCT06931405
View directory record Official record
Conditions
Chronic Inducible Urticaria, Chronic Spontaneous Urticaria
Interventions
BLU-808, Placebo
Drug
Lead sponsor
Blueprint Medicines Corporation
Industry
Eligibility
18 Years and older
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
27
States / cities
Birmingham, Alabama • Little Rock, Arkansas • La Jolla, California + 23 more
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Sep 22, 2026, 4:00 AM EDT
Completed No phase listed Observational

Long Term Patency Following Arterial Repair

NCT02228057
View directory record Official record
Conditions
Upper Extremity Arterial Surgery
Interventions
Not listed
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 12, 2015 · Synced Sep 22, 2026, 4:00 AM EDT
Completed Not applicable Interventional Results available

Heat Versus Ice in the Acute Management of Neck and Back Strain Injuries

NCT01535365
View directory record Official record
Conditions
Back Strain, Neck Strain
Interventions
Heat, Cold
Other
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Feb 16, 2012 · Synced Sep 22, 2026, 4:00 AM EDT
Completed Not applicable Interventional Results available

Procalcitonin Antibiotic Consensus Trial (ProACT)

NCT02130986
View directory record Official record
Conditions
Lower Respiratory Tract Infection (LRTI)
Interventions
Procalcitonin level, Results of procalcitonin (PCT) level to treating clinician, Provide procalcitonin guideline to treating clinician, Telephone Visit
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
1,664 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
13
States / cities
Birmingham, Alabama • Phoenix, Arizona • Orange, California + 8 more
Source: ClinicalTrials.gov public record
Updated Jan 14, 2019 · Synced Sep 22, 2026, 4:00 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Walnut and Immunity Study

NCT05915390
View directory record Official record
Conditions
Immune Response, Upper Respiratory Tract Infection
Interventions
walnuts, Habitual diet
Dietary Supplement
Lead sponsor
Loma Linda University
Other
Eligibility
55 Years to 75 Years
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Oct 1, 2024 · Synced Sep 22, 2026, 4:00 AM EDT
Recruiting Not applicable Interventional

Artificial Intelligence Diagnostic Decision Support to Reduce Antimicrobial Prescriptions in Young Children With Colds

NCT06876259
View directory record Official record
Conditions
Acute Otitis Media (AOM), Upper Respiratory Infection
Interventions
Standard Clinical Ear Exam, AI app ear exam and diagnosis
Diagnostic Test
Lead sponsor
Timothy Shope
Other
Eligibility
6 Months to 24 Months
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 6, 2026 · Synced Sep 22, 2026, 4:00 AM EDT
Enrolling by invitation Not applicable Interventional

Cold Snare Piecemeal Resection vs Cold Snare Endoscopic Mucosal Resection

NCT06462521
View directory record Official record
Conditions
Colon Cancer, Colon Polyp, Colon Adenoma, Serrated Polyp
Interventions
Cold Snare Piecemeal Resection (CSPR), Cold Snare Endoscopic Mucosal Resection (Cold EMR)
Procedure
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
570 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Dec 29, 2025 · Synced Sep 22, 2026, 4:00 AM EDT
Completed No phase listed Observational

Optimizing Clinical Use of Polymyxin B

NCT02682355
View directory record Official record
Conditions
Pneumonia, Blood Stream Infection, Urinary Tract Infections, Respiratory Tract Infection (Including Tracheobronchitis), Sepsis
Interventions
Not listed
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years and older
Enrollment
155 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
3
States / cities
Chicago, Illinois • New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 1, 2024 · Synced Sep 22, 2026, 4:00 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

LBNP Tolerance With Skin Warming After Exercise Cold Stress

NCT06279897
View directory record Official record
Conditions
Blood Pressure, Blood Loss
Interventions
Skin Surface Rewarming, Skin Surface Warming, Skin Surface Heating, Skin Surface Cooling
Other
Lead sponsor
University of Colorado, Colorado Springs
Other
Eligibility
18 Years to 40 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Colorado Springs, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 26, 2025 · Synced Sep 22, 2026, 4:00 AM EDT
Terminated Phase 1Phase 2 Interventional

A Dose Escalation/Expansion Study of MDK-703 in Patients With Advanced or Metastatic Solid Tumors

NCT05716295
View directory record Official record
Conditions
Advanced or Metastatic Solid Tumors
Interventions
MDK-703, Checkpoint Inhibitor, Immune
Drug
Lead sponsor
Medikine, Inc.
Industry
Eligibility
18 Years to 99 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
6
States / cities
Sarasota, Florida • Huntersville, North Carolina • Austin, Texas + 3 more
Source: ClinicalTrials.gov public record
Updated May 7, 2024 · Synced Sep 22, 2026, 4:00 AM EDT
Not listed Phase 1Phase 2 Interventional Accepts healthy volunteers

Reversal of Dual Antiplatelet Therapy With Cold Stored Platelets

NCT03787927
View directory record Official record
Conditions
Bleeding, Platelet Dysfunction Due to Drugs, Platelet Dysfunction
Interventions
Autologous Platelet Transfusion (room-temperature-stored), Autologous Platelet Transfusion (cold-stored 5 days), Autologous Platelet Transfusion (cold-stored 10 days), Autologous Platelet Transfusion (cold-stored 15 days), Aspirin, Clopidogrel
Drug
Lead sponsor
Bloodworks
Other
Eligibility
18 Years to 59 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jul 13, 2020 · Synced Sep 22, 2026, 4:00 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Vibrating, Cold Device for Pediatric Intravenous (IV) Cannulation Pain Relief

NCT01394250
View directory record Official record
Conditions
Pain, Anxiety
Interventions
Buzzy, Topical Lidocaine 4% Cream
Device · Drug
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
4 Years to 18 Years
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 15, 2016 · Synced Sep 22, 2026, 4:00 AM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Modafinil to Optimize the Performance of Cold-Stressed Sleep-Deprived Personnel

NCT07830056
View directory record Official record
Conditions
Sleep Deprivation, Cold Exposure
Interventions
Modafinil (M), 200 mg Microcrystalline Cellulose
Drug
Lead sponsor
United States Army Research Institute of Environmental Medicine
Federal
Eligibility
17 Years to 39 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Natick, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 20, 2026 · Synced Sep 22, 2026, 4:00 AM EDT