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Showing 1–24 of 243 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Colon Polyps Clear all
Completed Phase 2 Interventional Results available

Curcumin in Treating Patients With Familial Adenomatous Polyposis

NCT00641147
View directory record Official record
Conditions
Familial Adenomatous Polyposis
Interventions
Curcumin, Laboratory Biomarker Analysis, Placebo
Drug · Other
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years to 85 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 28, 2017 · Synced Jul 21, 2026, 4:43 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

S0000D: Effect of Vitamin E and/or Selenium on Colorectal Polyps in Men Enrolled on SELECT Trial SWOG-S0000

NCT00706121
View directory record Official record
Conditions
Colorectal Cancer, Precancerous Condition
Interventions
Vitamin E, Selenium, Vitamin E placebo, selenium placebo
Drug
Lead sponsor
SWOG Cancer Research Network
Network
Eligibility
50 Years to 120 Years · Male only
Enrollment
8,094 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2018
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Dec 15, 2019 · Synced Jul 21, 2026, 4:43 PM EDT
Terminated No phase listed Observational

The Utility of Time Segmental Withdrawal During Screening Colonoscopy for Increasing Adenoma Detection Rate.

NCT02538406
View directory record Official record
Conditions
Adenomatous Polyp of Colon
Interventions
Segmental withdrawal
Other
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years to 80 Years
Enrollment
232 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 27, 2020 · Synced Jul 21, 2026, 4:43 PM EDT
Completed Not applicable Interventional

Pivotal Study of the CapsoCam Colon (CV-3) in Detecting Colonic Polyps, Using Colonoscopy as the Reference

NCT04607746
View directory record Official record
Conditions
Colonic Polyp
Interventions
Capsule Endoscope
Device
Lead sponsor
Capso Vision, Inc.
Industry
Eligibility
45 Years to 75 Years
Enrollment
1,337 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
23
States / cities
Scottsdale, Arizona • Lancaster, California • Los Gatos, California + 20 more
Source: ClinicalTrials.gov public record
Updated Jul 7, 2025 · Synced Jul 21, 2026, 4:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of Cold Forcep and Cold Snare Polypectomy for Polyps Less Than or Equal to 3mm in Size During Colonoscopy

NCT04551001
View directory record Official record
Conditions
Colo-rectal Cancer, Polyp of Colon, Adenomatous Polyp of Colon
Interventions
Cold forcep polypectomy, Cold snare polypectomy
Procedure
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
181 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated May 16, 2022 · Synced Jul 21, 2026, 4:43 PM EDT
Completed Not applicable Interventional

Computer Aided Detection of Polyps in the Colon

NCT03925337
View directory record Official record
Conditions
Polyp, Adenomatous, Colo-rectal Cancer
Interventions
Computer Aided Diagnostic Software
Device
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
22 Years and older
Enrollment
234 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
4
States / cities
Chicago, Illinois • Boston, Massachusetts • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 19, 2021 · Synced Jul 21, 2026, 4:43 PM EDT
Completed Not applicable Interventional Results available

EndoRotor® Endoscopic Mucosal Resection System for the Colon

NCT04203667
View directory record Official record
Conditions
Polyp of Colon, Endoscopic Mucosal Resection, Recurrent Colon Adenoma
Interventions
EndoRotor Resection
Device
Lead sponsor
Interscope, Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Danville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 4, 2022 · Synced Jul 21, 2026, 4:43 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Resect and Discard Approach to Diminutive Colonic Polyps

NCT01877525
View directory record Official record
Conditions
Benign Polyps of Large Intestine
Interventions
Colonoscopy
Procedure
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
618 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 12, 2013 · Synced Jul 21, 2026, 4:43 PM EDT
Recruiting No phase listed Observational

A Study of a Urine Test to Detect Colorectal Cancer

NCT07649057
View directory record Official record
Conditions
Colorectal Cancer, Precancerous Polyp, Rectal Bleeding, CRC
Interventions
3-metabolite biosensor
Diagnostic Test
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 14, 2026 · Synced Jul 21, 2026, 4:43 PM EDT
Completed Not applicable Interventional

Improving the Frequency of Colonoscopy in Patients With a Previous Colorectal Polyp

NCT00397969
View directory record Official record
Conditions
Colorectal Cancer, Precancerous Condition
Interventions
counseling intervention, screening colonoscopy
Other · Procedure
Lead sponsor
Harvard Medical School (HMS and HSDM)
Other
Eligibility
21 Years and older
Enrollment
800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 18, 2013 · Synced Jul 21, 2026, 4:43 PM EDT
Completed Phase 1 Interventional

Panchromoendoscopy Using Oral Indigo Carmine Mixed With Polyethylene Glycol Prep

NCT01901510
View directory record Official record
Conditions
Colonic Polyps
Interventions
Chromoendoscopy (Indigo Carmine), Control
Drug · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
50 Years to 75 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Scottsdale, Arizona
Source: ClinicalTrials.gov public record
Updated Mar 2, 2015 · Synced Jul 21, 2026, 4:43 PM EDT
Completed Phase 2 Interventional

High-Dose Folic Acid in Preventing Colorectal Cancer in Patients Who Have Had Polyps Surgically Removed

NCT00002650
View directory record Official record
Conditions
Colorectal Cancer
Interventions
folic acid
Dietary Supplement
Lead sponsor
Eastern Cooperative Oncology Group
Network
Eligibility
21 Years to 120 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1995 – 2009
U.S. locations
8
States / cities
Chicago, Illinois • Boston, Massachusetts • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 21, 2023 · Synced Jul 21, 2026, 4:43 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Effect of Folate on Colon and Blood Cells

NCT00220012
View directory record Official record
Conditions
Subjects Will Have a Pre-cancerous Colorectal Polyp, Family Member Has History of Colorectal Adenoma of Adenocarcinoma
Interventions
Folate depletion and supplementation
Procedure
Lead sponsor
Rockefeller University
Other
Eligibility
40 Years to 72 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2008
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 14, 2013 · Synced Jul 21, 2026, 4:43 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Prevention of Colorectal Cancer Through Multiomics Blood Testing

NCT04369053
View directory record Official record
Conditions
Colon Cancer, Rectal Cancer, Colon Neoplasm, Colon Diseases, Colon Lesion, Colon Polyp, Colorectal Cancer, Polyp, Adenoma, Rectal Diseases, Gastrointestinal Tract Cancers
Interventions
Freenome test
Diagnostic Test
Lead sponsor
Freenome Holdings Inc.
Industry
Eligibility
45 Years to 85 Years
Enrollment
48,995 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
147
States / cities
Birmingham, Alabama • Huntsville, Alabama • Chandler, Arizona + 122 more
Source: ClinicalTrials.gov public record
Updated Dec 25, 2025 · Synced Jul 21, 2026, 4:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Capsule Endoscopy With PillCam® Colon 2 in Visualization of the Colon

NCT01269372
View directory record Official record
Conditions
Colorectal Lesions
Interventions
PillCam Colon 2, Colonoscopy
Device
Lead sponsor
Medtronic - MITG
Industry
Eligibility
50 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Chesapeake, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 30, 2020 · Synced Jul 21, 2026, 4:43 PM EDT
Completed Phase 2 Interventional Results available

Erlotinib Hydrochloride in Treating Patients With Stage I-III Colorectal Cancer or Adenoma

NCT00754494
View directory record Official record
Conditions
Adenomatous Polyp, Recurrent Colon Cancer, Recurrent Rectal Cancer, Stage I Colon Cancer, Stage I Rectal Cancer, Stage IIA Colon Cancer, Stage IIA Rectal Cancer, Stage IIB Colon Cancer, Stage IIB Rectal Cancer, Stage IIC Colon Cancer, Stage IIC Rectal Cancer, Stage IIIA Colon Cancer, Stage IIIA Rectal Cancer, Stage IIIB Colon Cancer, Stage IIIB Rectal Cancer, Stage IIIC Colon Cancer, Stage IIIC Rectal Cancer
Interventions
erlotinib hydrochloride, placebo, laboratory biomarker analysis
Drug · Other
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
3
States / cities
Long Beach, California • Orange, California • Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 5, 2015 · Synced Jul 21, 2026, 4:43 PM EDT
Not listed Not applicable Interventional

Online Education Module to Accurately Classify Polyp Size

NCT05846295
View directory record Official record
Conditions
Colorectal Polyp, Colonic Neoplasms
Interventions
ESTIMATE
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
Not listed
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Nov 29, 2023 · Synced Jul 21, 2026, 4:43 PM EDT
Not listed Not applicable Interventional

Prospective Study for Evaluating Colon Polyp Histology With in Vivo Probe Based Confocal Laser Endomicroscopy

NCT01214031
View directory record Official record
Conditions
Colon Polyps, Adenomatous Polyps, Colon Cancer
Interventions
Confocal laser endomicroscopy (CLE)
Device
Lead sponsor
Midwest Biomedical Research Foundation
Other
Eligibility
18 Years to 85 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 8, 2012 · Synced Jul 21, 2026, 4:43 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

CHOICE: Communicating Health Options Through Information and Cancer Education

NCT00134589
View directory record Official record
Conditions
Colorectal Neoplasms
Interventions
Academic Detailing (Medical Practices)+Decision Aids (Patients)
Behavioral
Lead sponsor
Centers for Disease Control and Prevention
Federal
Eligibility
52 Years to 75 Years
Enrollment
450 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2009
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 3, 2009 · Synced Jul 21, 2026, 4:43 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

A Prospective, Single Blinded Study for Predicting Colon Polyp Histology With Narrow Band Imaging

NCT00613262
View directory record Official record
Conditions
Colonoscopy, Adenomatous Polyp, Neoplastic
Interventions
Narrow Band Imaging
Other
Lead sponsor
Midwest Biomedical Research Foundation
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 8, 2012 · Synced Jul 21, 2026, 4:43 PM EDT
Completed Phase 1 Interventional Results available

Perfusion Assessment in Laparoscopic Left Anterior Resection

NCT01560377
View directory record Official record
Conditions
Rectal Cancer, Colon Cancer, Crohn's Disease, Polyp, Procidentia, Diverticulitis
Interventions
PINPOINT Endoscopic Fluorescence Imaging System
Device
Lead sponsor
Novadaq Technologies ULC, now a part of Stryker
Industry
Eligibility
18 Years and older
Enrollment
147 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
11
States / cities
Los Angeles, California • Orange, California • San Diego, California + 7 more
Source: ClinicalTrials.gov public record
Updated Dec 10, 2018 · Synced Jul 21, 2026, 4:43 PM EDT
Terminated Not applicable Interventional

Vitamin D Supplement in Preventing Colon Cancer in African Americans With Colon Polyps

NCT00870961
View directory record Official record
Conditions
Colorectal Cancer, Precancerous Condition
Interventions
cholecalciferol, placebo
Dietary Supplement · Other
Lead sponsor
Northwestern University
Other
Eligibility
50 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
2
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 15, 2013 · Synced Jul 21, 2026, 4:43 PM EDT
Terminated No phase listed Observational Results available

Observational Familial Adenomatous Polyposis Registry Study In Patients Receiving Celecoxib Compared to Control Patients

NCT00151476
View directory record Official record
Conditions
Familial Adenomatous Polyposis (FAP)
Interventions
Celecoxib, Routine Medical Care
Drug · Other
Lead sponsor
Pfizer
Industry
Eligibility
12 Years and older
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 3, 2024 · Synced Jul 21, 2026, 4:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

CB-17-08 Augmented Endoscopy System for Mucosal Lesion Detection During Colonoscopy for Colon Rectal Cancer.

NCT03954548
View directory record Official record
Conditions
Colorectal Cancer
Interventions
CB-17-08 CADe
Device
Lead sponsor
Cosmo Artificial Intelligence-AI Ltd
Industry
Eligibility
45 Years and older
Enrollment
249 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
7
States / cities
Scottsdale, Arizona • Danville, California • Jacksonville, Florida + 4 more
Source: ClinicalTrials.gov public record
Updated May 11, 2021 · Synced Jul 21, 2026, 4:43 PM EDT