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ClinicalTrials.gov public records Last synced Oct 20, 2026, 1:56 PM EDT

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Showing 1–24 of 30 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Colorectal Anastomosis Clear all
Completed Phase 2 Interventional Results available

A Study to Evaluate LB1148 for Return of Gastrointestinal Function and Adhesions in Subjects Undergoing Bowel Resection

NCT02836470
View directory record Official record
Conditions
Ileus, Post-Operative Adhesions
Interventions
LB1148, Placebo
Drug
Lead sponsor
Palisade Bio
Industry
Eligibility
18 Years to 80 Years
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
28
States / cities
Mobile, Alabama • Yuma, Arizona • Irvine, California + 20 more
Source: ClinicalTrials.gov public record
Updated Jun 21, 2024 · Synced Oct 20, 2026, 1:56 PM EDT
Recruiting Not applicable Interventional

Anastomotic Safety and Surveillance Using Real-time Enhanced Sensing Using xBar

NCT07337590
View directory record Official record
Conditions
Colorectal Cancer
Interventions
xBar™ System
Device
Lead sponsor
Exero Medical Ltd.
Industry
Eligibility
21 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
6
States / cities
Louisville, Kentucky • Baltimore, Maryland • Lincoln, Nebraska + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 16, 2026 · Synced Oct 20, 2026, 1:56 PM EDT
Completed Not applicable Interventional

Quality of Life in Patients That Undergo J Pouch or Side to End Coloanal Anastomosis for Rectal Cancer

NCT01182116
View directory record Official record
Conditions
Rectal Cancer
Interventions
J Pouch
Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 75 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2016
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 9, 2018 · Synced Oct 20, 2026, 1:56 PM EDT
Completed No phase listed Observational

Data Collection of Patients Treated With the ColonRing™ for the Creation of Circular Compression Anastomosis

NCT01301417
View directory record Official record
Conditions
Diverticulum, Colon, Colorectal Neoplasms, Crohn Disease, Colitis, Ulcerative, Colostomy, Ileostomy - Stoma, Rectal Prolapse, Intestinal Polyposis, Lymphoma, Endometriosis, Intestinal Volvulus
Interventions
ColonRing™
Device
Lead sponsor
novoGI
Industry
Eligibility
18 Years and older
Enrollment
171 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
Riverdale, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 5, 2013 · Synced Oct 20, 2026, 1:56 PM EDT
Completed Not applicable Interventional Results available

A Prospective, Multi-Center Evaluation of the ECHELON CIRCULAR Powered Stapler in Left-Sided Colorectal Anastomoses

NCT03326895
View directory record Official record
Conditions
Left-sided Colon Resection
Interventions
Left-sided colon resection
Device
Lead sponsor
Ethicon Endo-Surgery
Industry
Eligibility
18 Years and older
Enrollment
168 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
6
States / cities
Birmingham, Alabama • Orlando, Florida • Tampa, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated Jan 11, 2021 · Synced Oct 20, 2026, 1:56 PM EDT
Terminated Not applicable Interventional Results available

Bioabsorbable Staple Line Reinforcement in Colorectal,Coloanal and Ileoanal Anastomoses

NCT00663819
View directory record Official record
Conditions
Rectal Cancer, Ulcerative Colitis, Familial Adenomatous Polyposis, Diverticulitis
Interventions
GORE SEAMGUARD® Bioabsorbable Staple Line Reinforcement, Staple line without reinforcement
Device · Procedure
Lead sponsor
W.L.Gore & Associates
Industry
Eligibility
18 Years and older
Enrollment
258 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
16
States / cities
Mobile, Alabama • Los Angeles, California • Weston, Florida + 12 more
Source: ClinicalTrials.gov public record
Updated Apr 17, 2018 · Synced Oct 20, 2026, 1:56 PM EDT
Not listed Phase 3 Interventional

Efficacy and Safety of LifeSeal™ Kit for Colorectal Staple Line Sealing

NCT02907385
View directory record Official record
Conditions
Rectal Cancer, Anastomotic Leak
Interventions
LifeSeal™ Kit
Device
Lead sponsor
LifeBond Ltd.
Industry
Eligibility
21 Years and older
Enrollment
736 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
23
States / cities
Los Angeles, California • Stanford, California • Florida City, Florida + 17 more
Source: ClinicalTrials.gov public record
Updated Mar 30, 2018 · Synced Oct 20, 2026, 1:56 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Safety and Effectiveness Evaluation of the COLO-BT as an Alternative Treatment to the Ileostomy

NCT05826743
View directory record Official record
Conditions
Colorectal Surgery, Colorectal Cancer, Rectal/Anal, Ileostomy - Stoma, Anastomotic Leakage
Interventions
COLO BT™, Stoma Creation
Device · Other
Lead sponsor
JSR Medical Co., Ltd.
Industry
Eligibility
19 Years to 80 Years
Enrollment
256 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
3
States / cities
Buffalo, New York • Hershey, Pennsylvania • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 5, 2026 · Synced Oct 20, 2026, 1:56 PM EDT
Terminated Not applicable Interventional Results available

SafeHeal Colovac Colorectal Anastomosis Protection Device Evaluation (SAFE-2) Pivotal Study

NCT05010850
View directory record Official record
Conditions
Colorectal Cancer, Rectal Cancer, Rectal Tumor, Rectal/Anal
Interventions
Colovac, Stoma Creation
Device · Procedure
Lead sponsor
SafeHeal Inc
Industry
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
10
States / cities
Los Angeles, California • Tampa, Florida • Worcester, Massachusetts + 4 more
Source: ClinicalTrials.gov public record
Updated Jul 3, 2025 · Synced Oct 20, 2026, 1:56 PM EDT
Recruiting Not applicable Interventional

Efficacy and Safety of the CG-100 Intraluminal Bypass Device

NCT04184973
View directory record Official record
Conditions
Rectal Cancer, Rectal Tumor, Rectal/Anal
Interventions
CG-100 intraluminal bypass device, Stoma
Device · Procedure
Lead sponsor
Colospan Ltd.
Industry
Eligibility
22 Years to 70 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
6
States / cities
Irvine, California • San Diego, California • Aurora, Colorado + 3 more
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Oct 20, 2026, 1:56 PM EDT
Enrolling by invitation Not applicable Interventional

SafeHeal Colovac Anastomosis Protection Device Evaluation Pivotal Study

NCT07116668
View directory record Official record
Conditions
Colorectal Cancer, Stoma - Ileostomy
Interventions
Colovac Anastomosis Protection Device placement following low anterior resection of colon cancer
Device
Lead sponsor
SafeHeal Inc
Industry
Eligibility
22 Years and older
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
12
States / cities
Los Angeles, California • Miami, Florida • Tampa, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Oct 20, 2026, 1:56 PM EDT
Completed No phase listed Observational

Colorectal Resection in Emergency General Surgery

NCT05171088
View directory record Official record
Conditions
Colorectal Resection
Interventions
Not listed
Lead sponsor
Methodist Health System
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Dec 28, 2021 · Synced Oct 20, 2026, 1:56 PM EDT
Active, not recruiting Not applicable Interventional

ColoSeal™ ICD System Anastomotic Protection Pivotal Study

NCT07429110
View directory record Official record
Conditions
Rectal Cancer Surgery
Interventions
ColoSeal ICD System, Protective Diverting Ostomy
Device · Procedure
Lead sponsor
Averto Medical, Inc.
Industry
Eligibility
22 Years to 75 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
6
States / cities
Orlando, Florida • Weston, Florida • Columbus, Ohio + 3 more
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 20, 2026, 1:56 PM EDT
Enrolling by invitation No phase listed Observational

Surgical Site Infection Outcomes in Natural Orifice Intracorporeal Anastomosis and Extraction (NICE) Procedure - The NICE Trial

NCT06957236
View directory record Official record
Conditions
Diverticulitis, Surgical Site Infection, Surgical Site Infections, Colorectal Surgery, Robotic Surgical Procedures, Clinical Trials, Diverticulitis, Colonic, Diverticulitis Colon, Diverticulitis; Perforation, Bowel
Interventions
Not listed
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 8, 2025 · Synced Oct 20, 2026, 1:56 PM EDT
Recruiting Not applicable Interventional

Post-Market Study of the Signia Circular Stapler With Tri-Staple Technology in Left-sided Colon, Sigmoid, and Rectal Resections

NCT07351071
View directory record Official record
Conditions
Colorectal Anastomosis, Left-sided Colon Resection, Anastomotic Leak, Anastomotic Complication, Digestive System Diseases, Gastrointestinal Diseases, Colonic Diseases, Intestinal Diseases, Rectal Diseases, Postoperative Complications, Anastomotic Leaks
Interventions
Signia™ circular stapler with Tri-Staple™ Technology (Signia™ Circular Stapling system)
Device
Lead sponsor
Medtronic - MITG
Industry
Eligibility
18 Years and older
Enrollment
137 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
10
States / cities
New Haven, Connecticut • Tampa, Florida • Marietta, Georgia + 7 more
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Oct 20, 2026, 1:56 PM EDT
Active, not recruiting Phase 1Phase 2 Interventional

Intraoperative Use of Oxygen Saturation Imaging to Assess Intestinal Perfusion

NCT07587619
View directory record Official record
Conditions
Colorectal Cancer, Diverticulitis of Sigmoid
Interventions
Fujifilm monitoring
Device
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 20, 2026 · Synced Oct 20, 2026, 1:56 PM EDT
Recruiting Not applicable Interventional

Intra-Corporeal Anastomosis Result in Quicker Return of Bowel Function/Earlier Discharge

NCT03862781
View directory record Official record
Conditions
Colorectal Disorders
Interventions
Right Hemicolectomy
Procedure
Lead sponsor
Corewell Health West
Other
Eligibility
18 Years and older
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
Grand Rapids, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Oct 20, 2026, 1:56 PM EDT
Terminated No phase listed Observational

Ileal Pouch-Anal Anastomosis Registry

NCT01026480
View directory record Official record
Conditions
Ileal Pouch-Anal Anastomosis
Interventions
Not listed
Lead sponsor
Boston Medical Center
Other
Eligibility
Not listed
Enrollment
936 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 17, 2017 · Synced Oct 20, 2026, 1:56 PM EDT
Completed Not applicable Interventional Results available

Peri-Strips Dry (PSD) Veritas Collagen Matrix Staple Line Reinforcement for Colorectal Surgery

NCT00559013
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Staple line reinforcement
Device
Lead sponsor
Baxter Healthcare Corporation
Industry
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
2
States / cities
Burlington, Massachusetts • Saint Paul, Minnesota
Source: ClinicalTrials.gov public record
Updated May 10, 2017 · Synced Oct 20, 2026, 1:56 PM EDT
Completed Phase 4 Interventional Results available

COMPRES - COMpression Anastomosis Ring (CAR™ 27/ColonRing™) Post maRketing Evaluation Study

NCT01091155
View directory record Official record
Conditions
Colorectal Surgery
Interventions
ColonRing (Colorectal anastomosis)
Device
Lead sponsor
novoGI
Industry
Eligibility
18 Years and older
Enrollment
288 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
7
States / cities
Irvine, California • Los Angeles, California • Orlando, Florida + 4 more
Source: ClinicalTrials.gov public record
Updated Oct 25, 2013 · Synced Oct 20, 2026, 1:56 PM EDT
Terminated Not applicable Interventional Results available

A Study Assessing Perfusion Outcomes With PINPOINT® Near Infrared Fluorescence Imaging in Low Anterior Resection

NCT02205307
View directory record Official record
Conditions
Rectal Cancer, Rectosigmoid Cancer
Interventions
PINPOINT, SPY Elite
Device
Lead sponsor
Novadaq Technologies ULC, now a part of Stryker
Industry
Eligibility
18 Years and older
Enrollment
347 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
24
States / cities
Concord, California • Los Angeles, California • Orange, California + 18 more
Source: ClinicalTrials.gov public record
Updated Jun 24, 2020 · Synced Oct 20, 2026, 1:56 PM EDT
Not listed No phase listed Observational

A RETROspective Data Collection of comPRESSion Anastomosis Using the ColonRing

NCT01880918
View directory record Official record
Conditions
Diverticulum, Colon, Colorectal Neoplasms, Crohn Disease, Colitis, Ulcerative, Colostomy, Ileostomy - Stoma, Rectal Prolapse, Intestinal Polyposis, Lymphoma, Endometriosis, Intestinal Volvulus
Interventions
Not listed
Lead sponsor
novoGI
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
3
States / cities
Atlamonte Springs, Florida • Port Charlotte, Florida • Springfield, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 19, 2013 · Synced Oct 20, 2026, 1:56 PM EDT
Completed Not applicable Interventional Results available

Fluorescent Evaluation of Colorectal Anastamoses

NCT01424293
View directory record Official record
Conditions
Rectal Neoplasms, Colon Neoplasms, Diverticulitis
Interventions
Indocyanine Green, The SPY® Intraoperative Imaging System
Device
Lead sponsor
Maimonides Medical Center
Other
Eligibility
18 Years to 100 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Jul 13, 2021 · Synced Oct 20, 2026, 1:56 PM EDT
Terminated Phase 2 Interventional Results available

Sacral Nerve Stimulation in Treating Low Anterior Resection Syndrome or Fecal Incontinence in Patients With Locally Advanced Rectal Cancer or Other Pelvic Cancer, the RESTORE Study

NCT04066894
View directory record Official record
Conditions
Low Anterior Resection Syndrome, Malignant Anal Neoplasm, Malignant Bladder Neoplasm, Malignant Cervical Neoplasm, Malignant Ovarian Neoplasm, Malignant Pelvic Neoplasm, Malignant Prostate Neoplasm, Malignant Uterine Neoplasm, Malignant Vaginal Neoplasm, Malignant Vulvar Neoplasm, Rectal Carcinoma
Interventions
Explantation, Quality-of-Life Assessment, Questionnaire Administration, Sacral Nerve Stimulator, Sacral Nerve Stimulator Battery, Therapeutic Conventional Surgery
Procedure · Other · Device
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
2
States / cities
Houston, Texas • Sugar Land, Texas
Source: ClinicalTrials.gov public record
Updated Aug 14, 2023 · Synced Oct 20, 2026, 1:56 PM EDT