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ClinicalTrials.gov public records Last synced Oct 20, 2026, 11:41 PM EDT

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Showing 121–144 of 179 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Combat Stress Disorders Clear all
Completed Not applicable Interventional

NightWare Randomized Trial 02

NCT04040387
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Combat Disorders, Ptsd, Nightmare, Nightmares, REM-Sleep Type, Nightmare Disorder With Associated Non-Sleep Disorder
Interventions
NightWare Therapeutic System, Sham NightWare
Device
Lead sponsor
NightWare
Industry
Eligibility
22 Years and older
Enrollment
270 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
4
States / cities
Bethesda, Maryland • Minneapolis, Minnesota • Cleveland, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Oct 20, 2026, 11:41 PM EDT
Completed Not applicable Interventional

Variable-length Cognitive Processing Therapy for Combat-Related PTSD

NCT02313818
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Cognitive Processing Therapy-Cognitive Only
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Fort Hood, Texas
Source: ClinicalTrials.gov public record
Updated Jan 16, 2019 · Synced Oct 20, 2026, 11:41 PM EDT
Completed Not applicable Interventional

Attention Control Training for PTSD Related to Combat or Interpersonal Violence

NCT03350360
View directory record Official record
Conditions
PTSD
Interventions
Attention Control Training, Comparison Task
Behavioral
Lead sponsor
Creighton University
Other
Eligibility
19 Years to 80 Years
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Jul 19, 2022 · Synced Oct 20, 2026, 11:41 PM EDT
Completed Not applicable Interventional

Accelerated Image-Guided Robotically Delivered Transcranial Magnetic Stimulation for Combat PTSD

NCT06587659
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
Transcranial Magnetic Stimulation, Robotic Arm
Device
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 70 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
San Antoio, Texas
Source: ClinicalTrials.gov public record
Updated Oct 15, 2025 · Synced Oct 20, 2026, 11:41 PM EDT
Recruiting Not applicable Interventional

Effectiveness, Implementation, and Cost of Cognitive Processing Therapy in Prisons

NCT06923423
View directory record Official record
Conditions
PTSD - Post Traumatic Stress Disorder, PTSD and Alcohol Use Disorder, PTSD and Trauma-related Symptoms, Substance Use Disorder (SUD), Depression, Mental Health, Trauma, Trauma Exposure, Traumatic Stress Disorder, Traumatic Stress, Post Traumatic Stress Symptoms
Interventions
Group Cognitive Processing Therapy (CPT), Control Group Individual trauma focused self-help via workbook
Behavioral
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years and older
Enrollment
640 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
6
States / cities
Little Rock, Arkansas • Osceola, Arkansas • Texarkana, Arkansas + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 21, 2026 · Synced Oct 20, 2026, 11:41 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Computer Game, Qualitative, and MEG/EEG Assessment of Serotonergic Psychedelics

NCT06624137
View directory record Official record
Conditions
OCD, Major Depressive Disorder (MDD), Alcohol Use Disorder (AUD), Healthy Volunteer, Migraine, PTSD, PTSD - Post Traumatic Stress Disorder, Addiction, Tobacco Use Disorder, Obsessive Compulsive Disorder (OCD), Opioid Use Disorder
Interventions
Serotonergic Psychedelic, Placebo
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 65 Years
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
2
States / cities
Hamden, Connecticut • West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Oct 20, 2026, 11:41 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Nutrition for Trauma Community Survey

NCT06864637
View directory record Official record
Conditions
Psychological Trauma, Historical, Nutrition, PTSD - Post Traumatic Stress Disorder
Interventions
Not listed
Lead sponsor
True Paleo Inc.
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Oct 20, 2026, 11:41 PM EDT
Not yet recruiting Phase 4 Interventional

Suvorexant 3 - PE-PC

NCT07686731
View directory record Official record
Conditions
PTSD - Post Traumatic Stress Disorder, Insomnia, TBI (Traumatic Brain Injury)
Interventions
Suvorexant, Placebo, Prolonged Exposure Therapy for Primary Care (PE-PC)
Drug · Behavioral
Lead sponsor
Northern California Institute of Research and Education
Other
Eligibility
18 Years to 75 Years
Enrollment
142 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Oct 20, 2026, 11:41 PM EDT
Terminated Phase 2 Interventional

Exercise: A Novel Treatment for Combat Post Traumatic Stress Disorder

NCT01626131
View directory record Official record
Conditions
Post-Traumatic Stress Disorder
Interventions
exercise training, Stretching training
Behavioral
Lead sponsor
INTRuST, Post-Traumatic Stress Disorder - Traumatic Brain Injury Clinical Consortium
Other
Eligibility
18 Years to 65 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 26, 2013 · Synced Oct 20, 2026, 11:41 PM EDT
Recruiting Phase 3 Interventional Accepts healthy volunteers

REVEAL Study - Diagnostic Testing for PTSD Using the Senseye Diagnostic Tool

NCT07280065
View directory record Official record
Conditions
PTSD - Post Traumatic Stress Disorder
Interventions
Senseye Diagnostic Tool (DT), Clinician Administered PTSD Scale for DSM-5, Revised Version
Device · Behavioral
Lead sponsor
Senseye, Inc.
Industry
Eligibility
18 Years and older
Enrollment
1,900 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
5
States / cities
Aurora, Colorado • Savannah, Georgia • Meridian, Idaho + 2 more
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Oct 20, 2026, 11:41 PM EDT
Completed Phase 3 Interventional Results available

Enhancing Exposure Therapy for Post Traumatic Stress Disorder (PTSD): Virtual Reality and Imaginal Exposure With a Cognitive Enhancer

NCT01352637
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
DCS (D-Cycloserine ) + Prolonged Imaginal Exposure, DCS (D-Cycloserine ) + Virtual Reality Exposure, Placebo + Prolonged Imaginal Exposure, Placebo (sugar pill) + Virtual Reality Exposure
Drug
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 70 Years
Enrollment
192 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2018
U.S. locations
5
States / cities
Long Beach, California • Los Angeles, California • Atlanta, Georgia + 2 more
Source: ClinicalTrials.gov public record
Updated Jul 2, 2019 · Synced Oct 20, 2026, 11:41 PM EDT
Completed Not applicable Interventional Results available

Study of PTSD in Military Veterans Who Have Suffered Traumatic Brain Injuries

NCT02003352
View directory record Official record
Conditions
PTSD, TBI
Interventions
Functional Neurological Rehabilitation
Procedure
Lead sponsor
Carrick Institute for Graduate Studies
Other
Eligibility
18 Years to 60 Years
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
1
States / cities
Irving, Texas
Source: ClinicalTrials.gov public record
Updated Mar 23, 2017 · Synced Oct 20, 2026, 11:41 PM EDT
Terminated Not applicable Interventional Results available

Prazosin vs Paroxetine in Combat Stress-Related Post-Traumatic Stress Disorder (PTSD) Nightmares & Sleep Disturbance

NCT00202449
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Sleep Disorders
Interventions
prazosin, paroxetine, Placebo
Drug
Lead sponsor
Seattle Institute for Biomedical and Clinical Research
Other
Eligibility
18 Years to 50 Years
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Fort Lewis, Washington
Source: ClinicalTrials.gov public record
Updated Jul 10, 2018 · Synced Oct 20, 2026, 11:41 PM EDT
Completed Not applicable Interventional Results available

Image-guided, Robotically Delivered Transcranial Magnetic Stimulation Treatment for Combat-Related Post-Traumatic Stress Disorder

NCT02853032
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
Active repetitive transcranial magnetic stimulation, robotic arm, Sham repetitive transcranial magnetic stimulation
Device
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 65 Years
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Nov 3, 2020 · Synced Oct 20, 2026, 11:41 PM EDT
Recruiting Not applicable Interventional

Treatment for PTSD and Tinnitus

NCT07106593
View directory record Official record
Conditions
PTSD - Post Traumatic Stress Disorder, Posttraumatic Stress Disorder (PTSD), Tinnitus
Interventions
Cognitive Processing Therapy, CBT-t
Behavioral
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Oct 20, 2026, 11:41 PM EDT
Withdrawn Not applicable Interventional

Effect of Prazosin on Neurophysiology and Cognition in Post-Traumatic Stress Disorder (PTSD)

NCT00890643
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
prazosin hydrochloride, placebo
Drug
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Sep 23, 2013 · Synced Oct 20, 2026, 11:41 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Experiential Avoidance in Combat Veterans With and Without Posttraumatic Stress Disorder

NCT01652430
View directory record Official record
Conditions
PTSD, Suicidal Ideation
Interventions
Not listed
Lead sponsor
VA Eastern Colorado Health Care System
Federal
Eligibility
18 Years to 65 Years
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Jan 8, 2015 · Synced Oct 20, 2026, 11:41 PM EDT
Not listed Phase 3 Interventional

A Head-to-head Comparison of Virtual Reality Treatment for Post Traumatic Stress Disorder

NCT00978484
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
Virtual Reality Exposure Therapy - Dynamic, Augmented Exposure Therapy
Behavioral
Lead sponsor
United States Naval Medical Center, San Diego
Federal
Eligibility
18 Years to 65 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
2
States / cities
Camp Pendlton, California • San Diego, California
Source: ClinicalTrials.gov public record
Updated Jun 30, 2014 · Synced Oct 20, 2026, 11:41 PM EDT
Completed Not applicable Interventional

Traumatic Nightmares Treated by NightWare (To Arouse Not Awaken)

NCT03795987
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Combat Disorders, Ptsd, Nightmare, Nightmares, REM-Sleep Type, Nightmare Disorder With Associated Non-Sleep Disorder
Interventions
NightWare Therapeutic System
Device
Lead sponsor
NightWare
Industry
Eligibility
22 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 26, 2020 · Synced Oct 20, 2026, 11:41 PM EDT
Completed Not applicable Interventional Results available

A Placebo-Controlled Trial of D-Cycloserine and Exposure Therapy for Combat-PTSD

NCT00371176
View directory record Official record
Conditions
Combat Disorders, Stress Disorders, Post-Traumatic
Interventions
Exposure therapy, D-Cycloserine, Placebo pill
Behavioral · Drug · Other
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 4, 2014 · Synced Oct 20, 2026, 11:41 PM EDT
Recruiting Not applicable Interventional

Accelerated Treatment for Co-occurring Insomnia, Nightmares, and PTSD

NCT07069517
View directory record Official record
Conditions
Insomnia, PTSD - Post Traumatic Stress Disorder, Nightmares
Interventions
Cognitive-Behavioral Therapy for Insomnia (CBTi), Cognitive Behavioral Therapy for Nightmares (CBTn), Written Exposure Therapy (WET), Sleep Hygiene
Behavioral
Lead sponsor
Palo Alto Veterans Institute for Research
Other
Eligibility
18 Years to 65 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Kileen, Texas
Source: ClinicalTrials.gov public record
Updated Dec 3, 2025 · Synced Oct 20, 2026, 11:41 PM EDT
Completed Not applicable Interventional

An Open-Trial of Web-Prolonged Exposure (Web-PE) Among Active-Duty Military

NCT03337750
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Combat Disorders
Interventions
Web-PE Therapy
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 65 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
2
States / cities
Philadelphia, Pennsylvania • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Feb 19, 2020 · Synced Oct 20, 2026, 11:41 PM EDT
Recruiting Not applicable Interventional

Targeted Plasticity Therapy for PTSD

NCT06266364
View directory record Official record
Conditions
PTSD, Post Traumatic Stress Disorder
Interventions
Active VNS stimulation, Sham VNS stimulation
Device
Lead sponsor
The University of Texas at Dallas
Other
Eligibility
22 Years to 79 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
3
States / cities
Austin, Texas • Dallas, Texas • Richardson, Texas
Source: ClinicalTrials.gov public record
Updated Sep 16, 2026 · Synced Oct 20, 2026, 11:41 PM EDT
Recruiting Phase 2 Interventional

HBOT Effects on First Responders' Cognition and Well-Being

NCT07852728
View directory record Official record
Conditions
Traumatic Brain Injury, PTSD - Post Traumatic Stress Disorder, Anxiety, Depression, Post Concussion Symptoms
Interventions
Hyperbaric Oxygen Therapy (HBOT)
Drug
Lead sponsor
Summit Hyperbarics and Wellness
Other
Eligibility
18 Years to 75 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Boise, Idaho
Source: ClinicalTrials.gov public record
Updated Oct 1, 2026 · Synced Oct 20, 2026, 11:41 PM EDT