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ClinicalTrials.gov public records Last synced Oct 21, 2026, 1:03 AM EDT

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Showing 145–168 of 179 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Combat Stress Disorders Clear all
Completed Not applicable Interventional

Psychotherapy Treatment of Deployment-Related PTSD in Primary Care Settings

NCT00974402
View directory record Official record
Conditions
Post-Traumatic Stress Disorders, Stress Disorders, Combat Disorders
Interventions
Cognitive Behavioral Therapy
Behavioral
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
3
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Sep 18, 2014 · Synced Oct 21, 2026, 1:03 AM EDT
Completed Not applicable Interventional Results available

Neuroimaging the Impact of Treatment on Neural Substrates of Trust in Post-Traumatic Stress Disorder (PTSD)

NCT01244477
View directory record Official record
Conditions
Stress Disorders, Post Traumatic, Trust
Interventions
Group CPT-C
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 50 Years
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2018
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 27, 2019 · Synced Oct 21, 2026, 1:03 AM EDT
Completed Not applicable Interventional Results available

DoD PTSD November 13 - Information Processing Modification in the Treatment of PTSD

NCT00604045
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
Attention Bias Modification (ABM), Attention Control Condition (ACC)
Behavioral
Lead sponsor
San Diego State University
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Mar 28, 2014 · Synced Oct 21, 2026, 1:03 AM EDT
Not listed Not applicable Interventional

Cranial Electrotherapy Stimulation (CES) for Soldiers With Combat-Related Symptoms

NCT00866411
View directory record Official record
Conditions
Combat Related Symptoms, Irritability, Anger
Interventions
cranial electrotherapy stimulation (CES) with Alpha-Stim, placebo
Procedure
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
2
States / cities
Fort Hood, Texas • Fort Sam Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 20, 2009 · Synced Oct 21, 2026, 1:03 AM EDT
Completed Phase 3 Interventional

Individual PE vs Couples' CBT for Combat-Related Posttraumatic Stress Disorder

NCT02336971
View directory record Official record
Conditions
PTSD, Marital Relationship
Interventions
CBCT for PTSD, Prolonged Exposure
Behavioral
Lead sponsor
Toronto Metropolitan University
Other
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
3
States / cities
Fort Hood, Texas • Fort Sam Houston, Texas • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Oct 7, 2016 · Synced Oct 21, 2026, 1:03 AM EDT
Withdrawn Not applicable Interventional

Telepharmacy Robotic Medicine Delivery Unit "TRMDU" Assessment

NCT01007006
View directory record Official record
Conditions
Traumatic Brain Injury, Posttraumatic Stress Disorders, Trauma, Combat Disorders, Pain
Interventions
TMRDU
Device
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
3
States / cities
Camp Pendleton, California • Tampa, Florida • Fort Knox, Kentucky
Source: ClinicalTrials.gov public record
Updated Jul 26, 2019 · Synced Oct 21, 2026, 1:03 AM EDT
Not listed Not applicable Interventional

NightWare Open Enrollment Study

NCT03828656
View directory record Official record
Conditions
PostTraumatic Stress Disorder, Sleep Disorder, Stress Disorder, Sleep Initiation and Maintenance Disorders, Combat Disorders, Nightmares Associated With Chronic Post-Traumatic Stress Disorder, Nightmare, Nightmares, REM-Sleep Type
Interventions
NightWare Therapeutic System
Device
Lead sponsor
NightWare
Industry
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Mar 4, 2021 · Synced Oct 21, 2026, 1:03 AM EDT
Recruiting No phase listed Observational

Integrative Bilateral Cervical Sympathetic Blocks for Trauma-Related Symptoms in Special Operations Veterans: A Prospective Case Series

NCT07473505
View directory record Official record
Conditions
PTSD, Trauma-related Mental Health Symptoms, Moral Injury, Anxiety, Traumatic Brain Injury
Interventions
stellate ganglion block with 0.5% ropivacaine
Procedure
Lead sponsor
Reset Medical and Wellness Center
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Strongsville, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 20, 2026 · Synced Oct 21, 2026, 1:03 AM EDT
Completed Not applicable Interventional

A Comparison of Web-Prolonged Exposure (Web-PE) and Present-Centered Therapy (PCT) for PTSD Among Active-Duty Military Personnel

NCT02556645
View directory record Official record
Conditions
Posttraumatic Stress Disorders, Combat Disorders
Interventions
Web-PE Therapy, Therapist-Delivered Present-Centered Therapy
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
4
States / cities
Atlanta, Georgia • Philadelphia, Pennsylvania • Killeen, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 9, 2019 · Synced Oct 21, 2026, 1:03 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Foundational Programs to Combat Clinician Stress

NCT07220421
View directory record Official record
Conditions
Burnout, Professional, Stress, Psychological, Stress, Physiological, Psychological Well-Being, Mind-Body Therapies, Work Related Stress
Interventions
Sudarshan Kriya Yoga (SKY) Breathing and Sahaj Meditation, Health Education Program (HEP)
Behavioral · Other
Lead sponsor
Lancaster General Hospital
Other
Eligibility
25 Years to 70 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
6
States / cities
Boston, Massachusetts • Plainsboro, New Jersey • Lancaster, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 23, 2025 · Synced Oct 21, 2026, 1:03 AM EDT
Completed Not applicable Interventional

Brief Exposure and Exercise for PTSD.

NCT07080606
View directory record Official record
Conditions
PTSD - Post Traumatic Stress Disorder
Interventions
Brief exposure therapy and exercise
Behavioral
Lead sponsor
Troy Hubert
Other
Eligibility
18 Years to 64 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Apr 8, 2026 · Synced Oct 21, 2026, 1:03 AM EDT
Completed Not applicable Interventional Results available

Extinction of Fear Memories With Glucocorticoids in Veterans With PTSD

NCT01090180
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Dexamethasone, Placebo (sugar pill)
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older · Male only
Enrollment
129 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Nov 25, 2016 · Synced Oct 21, 2026, 1:03 AM EDT
Completed Not applicable Interventional

Massed Cognitive Processing Therapy for Combat-related PTSD

NCT03808727
View directory record Official record
Conditions
PTSD, Post Traumatic Stress Disorder
Interventions
Cognitive Processing Therapy
Behavioral
Lead sponsor
VA Boston Healthcare System
Federal
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Fort Belvoir, Virginia
Source: ClinicalTrials.gov public record
Updated May 6, 2023 · Synced Oct 21, 2026, 1:03 AM EDT
Completed Not applicable Interventional

Evaluation of Telehealth Interventions for Post-Trauma Stress

NCT00350584
View directory record Official record
Conditions
Post Traumatic Stress Disorders
Interventions
Mindfulness Telehealth Intervention, Psychoeducation Telehealth Intervention
Behavioral
Lead sponsor
VA Boston Healthcare System
Federal
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 29, 2011 · Synced Oct 21, 2026, 1:03 AM EDT
Completed Not applicable Interventional

Empowering Perinatal Adolescents Through Writing

NCT06771817
View directory record Official record
Conditions
Post-Traumatic Stress Disorder in Adolescence, PTSD - Post Traumatic Stress Disorder, PTSD and Trauma-related Symptoms, Pregnancy and PTSD
Interventions
Written Exposure Therapy
Behavioral
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
15 Years to 24 Years · Female only
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Sep 15, 2026 · Synced Oct 21, 2026, 1:03 AM EDT
Recruiting Not applicable Interventional

Shared Decision Making in PTSD Treatment

NCT06953687
View directory record Official record
Conditions
Post Traumatic Stress Disorder PTSD
Interventions
Prolonged Exposure Therapy, Cognitive Processing Therapy, Written Exposure Therapy, Shared Decision Making (SHARE)
Behavioral · Other
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
Fort Hood, Texas • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Oct 21, 2026, 1:03 AM EDT
Completed Not applicable Interventional

Clinical Effectiveness Trial of In-Home Cognitive Processing Therapy for Combat-Related PTSD

NCT02290847
View directory record Official record
Conditions
Posttraumatic Stress Disorder, PTSD
Interventions
Cognitive Processing Therapy (cognitive only version; CPT-C)
Behavioral
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years and older
Enrollment
172 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jun 4, 2020 · Synced Oct 21, 2026, 1:03 AM EDT
Completed Not applicable Interventional

Group Cognitive Processing Therapy for Combat-related Posttraumatic Stress Disorder (PTSD)

NCT01286415
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Group Cognitive Processing Therapy-Cognitive Only, Group Present Centered Therapy
Behavioral
Lead sponsor
VA Boston Healthcare System
Federal
Eligibility
18 Years and older
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Fort Hood, Texas
Source: ClinicalTrials.gov public record
Updated Mar 27, 2017 · Synced Oct 21, 2026, 1:03 AM EDT
Not listed No phase listed Observational

Vietnam Era Health Retrospective Observational Study

NCT02825602
View directory record Official record
Conditions
Aging, Combat Disorders
Interventions
Not listed
Lead sponsor
Veteran Affairs Office of Patient Care Services
Federal
Eligibility
58 Years and older
Enrollment
24,306 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Apr 24, 2019 · Synced Oct 21, 2026, 1:03 AM EDT
Completed Not applicable Interventional

Positive Suggestions Via MP3 Messages

NCT04437095
View directory record Official record
Conditions
Post Intensive Care Unit Syndrome, Psychological Trauma, Anxiety, Depression, PTSD
Interventions
Psychological Support Based on Positive Suggestion delivered via pre-recorded MP3 message
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
149 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 28, 2025 · Synced Oct 21, 2026, 1:03 AM EDT
Completed Not applicable Interventional Results available

Integrated Treatment of OEF/OIF Veterans With PTSD & Substance Use Disorders

NCT01338506
View directory record Official record
Conditions
Posttraumatic Stress Disorders, Combat Disorders, Alcohol Dependence, Drug Dependence
Interventions
Concurrent Treatment with Prolonged Exposure (COPE)
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Feb 11, 2020 · Synced Oct 21, 2026, 1:03 AM EDT
Not listed Phase 4 Interventional

Predictors of Treatment Response to Fluoxetine in PTSD Following a Recent History of War Zone Stress Exposure

NCT00633685
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Combat-related
Interventions
Fluoxetine, Placebo
Drug
Lead sponsor
TEMPVA Research Group, Inc.
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Fort Hood, Texas
Source: ClinicalTrials.gov public record
Updated May 25, 2010 · Synced Oct 21, 2026, 1:03 AM EDT
Completed Phase 4 Interventional Results available

Tramadol Extended-Release (ER) for Posttraumatic Stress Disorder (PTSD)

NCT01517711
View directory record Official record
Conditions
Post-Traumatic Stress Disorder
Interventions
Tramadol, Placebo
Drug
Lead sponsor
INTRuST, Post-Traumatic Stress Disorder - Traumatic Brain Injury Clinical Consortium
Other
Eligibility
21 Years to 55 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 31, 2022 · Synced Oct 21, 2026, 1:03 AM EDT
Completed Not applicable Interventional Results available

Prazosin Augmentation of Outpatient Treatment of Alcohol Use Disorders in Active Duty Soldiers With and Without PTSD

NCT02226367
View directory record Official record
Conditions
Alcohol Use Disorders, Stress Disorders, Posttraumatic, Combat Disorders
Interventions
prazosin hydrochloride, placebo
Drug
Lead sponsor
Seattle Institute for Biomedical and Clinical Research
Other
Eligibility
21 Years and older
Enrollment
158 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Tacoma, Washington
Source: ClinicalTrials.gov public record
Updated Feb 3, 2023 · Synced Oct 21, 2026, 1:03 AM EDT