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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Complication of Anesthesia Clear all
Terminated Phase 4 Interventional Results available

Phenylephrine Versus Ephedrine in Pre-eclampsia

NCT02025426
View directory record Official record
Conditions
Pre-eclampsia
Interventions
Phenylephrine, Ephedrine
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 13, 2020 · Synced Sep 17, 2026, 4:40 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Ketamine to Improve Recovery After Cesarean Delivery - Part 1

NCT04037085
View directory record Official record
Conditions
Obstetric Pain, Postpartum Depression, Breastfeeding, Pain, Acute, Pain, Chronic, Obstetric Anesthesia Problems, Drug Effect, Opioid Use
Interventions
Ketamine
Drug
Lead sponsor
Grace Lim, MD, MS
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 19, 2022 · Synced Sep 17, 2026, 4:40 AM EDT
Completed Not applicable Interventional

Pain Management After TKA: Comparison of Short- and Long-term Nerve Blocks

NCT03245359
View directory record Official record
Conditions
Anesthesia, Local, Pain, Postoperative
Interventions
Short-term ON-Q, Short-term ON-Q, Long-term ON-Q, Long-term ON-Q
Device · Drug
Lead sponsor
AdventHealth
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Aug 1, 2019 · Synced Sep 17, 2026, 4:40 AM EDT
Terminated Phase 4 Interventional Results available

Perioperative Propranolol in Patients With Post Traumatic Stress Disorder (PTSD)

NCT01555554
View directory record Official record
Conditions
Post-traumatic Stress Disorder
Interventions
Propranolol Hydrochloride, Placebo
Drug · Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
40 Years and older
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2019
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Sep 17, 2026, 4:40 AM EDT
Terminated Not applicable Interventional

Serratus Anterior Plane Block for Management of Post Thoracotomy Pain

NCT04258436
View directory record Official record
Conditions
Opioid Use, Post-thoracotomy Pain Syndrome, Local Anaesthetic Agent Overdose, Local Anesthetic Complication, Pain, Postoperative
Interventions
Serratus anterior block
Procedure
Lead sponsor
Indiana University
Other
Eligibility
38 Weeks to 12 Months
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jun 17, 2023 · Synced Sep 17, 2026, 4:40 AM EDT
Terminated Phase 4 Interventional

iPACK Block With Dexamethasone For Total Knee Replacement

NCT04917055
View directory record Official record
Conditions
Knee Osteoarthritis, Acute Pain, Anesthesia, Local, Regional Anesthesia
Interventions
ropivacaine 0.25% with epinephrine and 6mg dexamethasone, Saline
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Nov 6, 2023 · Synced Sep 17, 2026, 4:40 AM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

A Study to Compare Neostigmine vs Sugammadex in Length of PACU Stay in Patients Undergoing Sleeve Gastrectomy Surgery

NCT03276026
View directory record Official record
Conditions
Postoperative Nausea and Vomiting, Respiratory Conditions Due to Other External Agents
Interventions
Sugammadex, Neostigmine
Drug
Lead sponsor
Virtua Health, Inc.
Other
Eligibility
18 Years to 85 Years
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Mount Holly, New Jersey
Source: ClinicalTrials.gov public record
Updated May 27, 2019 · Synced Sep 17, 2026, 4:40 AM EDT
Terminated Not applicable Interventional

Intraoperative Anesthesia Care Transition Checklist

NCT02453828
View directory record Official record
Conditions
Postoperative Complications
Interventions
Non-cardiac surgery
Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
7,348 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 9, 2019 · Synced Sep 17, 2026, 4:40 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Oral Intake During Labor

NCT03276741
View directory record Official record
Conditions
Labor Complication, Food Aspiration, Complication of Anesthesia, Satisfaction
Interventions
gastric soft/bland diet
Dietary Supplement
Lead sponsor
David Grant U.S. Air Force Medical Center
Federal
Eligibility
18 Years and older · Female only
Enrollment
126 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Travis Air Force Base, California
Source: ClinicalTrials.gov public record
Updated Apr 23, 2020 · Synced Sep 17, 2026, 4:40 AM EDT
Recruiting Phase 4 Interventional

The Choice of Vasopressor to Prevent Postoperative Acute Kidney Injury After Major Non-Cardiac Surgery

NCT06802224
View directory record Official record
Conditions
Anesthesia, Surgery With General Anesthesia, Noncardiac Surgery, Hypotension During Surgery, Acute Kidney Injury (AKI), Myocardial Injury After Noncardiac Surgery (MINS), Vasopressor
Interventions
Norepinephrine, Phenylephrine
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
18,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
9
States / cities
San Francisco, California • College Park, Maryland • Ann Arbor, Michigan + 6 more
Source: ClinicalTrials.gov public record
Updated May 25, 2026 · Synced Sep 17, 2026, 4:40 AM EDT
Not listed Not applicable Interventional

Medial Versus Traditional Approach to US-guided TAP Blocks for Open Inguinal Hernia Repair

NCT01589796
View directory record Official record
Conditions
Abdominal Muscles/Ultrasonography, Adult, Ambulatory Surgical Procedures, Anesthetics, Local/Administration & Dosage, Ropivacaine/Administration & Dosage, Ropivacaine/Analogs & Derivatives, Hernia, Inguinal/Surgery, Humans, Nerve Block/Methods, Pain Measurement/Methods, Pain, Postoperative/Prevention & Control, Ultrasonography, Interventional
Interventions
TAP block
Procedure
Lead sponsor
Stamford Anesthesiology Services, PC
Other
Eligibility
18 Years to 75 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2012
U.S. locations
2
States / cities
Stamford, Connecticut
Source: ClinicalTrials.gov public record
Updated May 1, 2012 · Synced Sep 17, 2026, 4:40 AM EDT
Completed Not applicable Interventional

Post Anesthesia Care Unit (PACU) Weighted Blanket Study

NCT05632640
View directory record Official record
Conditions
Cardiac Catheterization, Electrophysiology Procedure, Pediatric Cardiology
Interventions
Standard of Care, Weighted blanket
Other · Device
Lead sponsor
University of Michigan
Other
Eligibility
3 Years to 17 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 24, 2025 · Synced Sep 17, 2026, 4:40 AM EDT
Completed Phase 4 Interventional

Sub-Paraspinal Block in Nuss Patients. A Pilot Project

NCT02169297
View directory record Official record
Conditions
Pectus Excavatum, Pain, Postoperative
Interventions
Ultrasound-guided Sub-Paraspinal Block, PCA only
Procedure
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
12 Years to 17 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 22, 2014 · Synced Sep 17, 2026, 4:40 AM EDT
Recruiting No phase listed Observational

Understanding the Acute Pain Phenotype in Patients Undergoing Surgery

NCT06466941
View directory record Official record
Conditions
Acute Pain, Chronic Post Operative Pain, Opioid Use
Interventions
regional anesthesia, no regional anesthesia, acute pain consultation, no acute pain consultation
Procedure · Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Sep 17, 2026, 4:40 AM EDT
Completed Phase 2 Interventional Results available

Granisetron Transdermal Patch for Prevention of Postoperative Nausea and Vomiting

NCT02457195
View directory record Official record
Conditions
Postoperative Nausea and Vomiting
Interventions
granisetron
Drug
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years to 89 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 17, 2019 · Synced Sep 17, 2026, 4:40 AM EDT
Completed Not applicable Interventional

Improving Surgical Patient Outcomes Through Implementation of a SemiStructured Intraoperative Anesthesia Handoff Tool

NCT06533111
View directory record Official record
Conditions
Post-operative Complications
Interventions
Epic Health Record semi-structured handoff cognitive aid, Usual care
Other
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 105 Years
Enrollment
3,763 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Sep 17, 2026, 4:40 AM EDT
Completed Not applicable Interventional Results available

Opioid Use After Thyroid and Parathyroid Surgeries

NCT04955444
View directory record Official record
Conditions
Thyroidectomy, Parathyroidectomy, Opioid Use, Pain, Postoperative
Interventions
Quality improvement bundle
Other
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 4, 2023 · Synced Sep 17, 2026, 4:40 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Real-Time Acute Kidney Injury Perioperative Prediction Clinical Trial

NCT07604662
View directory record Official record
Conditions
Acute Kidney Injury, Surgery Complications, Anesthesia
Interventions
EHR-Embedded AKI Risk Score, EHR-Embedded AKI Risk Score with Best Practice Advisory
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
25,518 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Sep 17, 2026, 4:40 AM EDT
Completed Not applicable Interventional

Randomized Study Comparing the Use of Epidural Analgesia to Intravenous Narcotics for Laparoscopic Colorectal Resection.

NCT02086123
View directory record Official record
Conditions
Pain, Postoperative
Interventions
Epidural Analgesia, Parenteral Analgesia (Intravenous)
Procedure
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Aug 13, 2023 · Synced Sep 17, 2026, 4:40 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Exparel Use in Bilateral TAP Blocks for Postoperative Pain Control

NCT03878888
View directory record Official record
Conditions
Postoperative Pain, Surgery, Anesthesia, Local
Interventions
Exparel 266 MG Per 20 ML Injection
Drug
Lead sponsor
St. Luke's Hospital, Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Bethlehem, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 16, 2020 · Synced Sep 17, 2026, 4:40 AM EDT
Completed No phase listed Observational

Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care

NCT01431326
View directory record Official record
Conditions
Adenovirus, Anesthesia, Anxiety, Anxiolysis, Autism, Autistic Disorder, Bacterial Meningitis, Bacterial Septicemia, Benzodiazepine, Bipolar Disorder, Bone and Joint Infections, Central Nervous System Infections, Convulsions, Cytomegalovirus Retinitis, Early-onset Schizophrenia Spectrum Disorders, Epilepsy, General Anesthesia, Gynecologic Infections, Herpes Simplex Virus, Infantile Hemangioma, Infection, Inflammation, Inflammatory Conditions, Intra-abdominal Infections, Lower Respiratory Tract Infections, Migraines, Pain, Pneumonia, Schizophrenia, Sedation, Seizures, Skeletal Muscle Spasms, Skin and Skin-structure Infections, Treatment-resistant Schizophrenia, Urinary Tract Infections, Withdrawal, Sepsis, Gram-negative Infection, Bradycardia, Cardiac Arrest, Cardiac Arrhythmia, Staphylococcal Infections, Nosocomial Pneumonia, Neuromuscular Blockade, Methicillin Resistant Staphylococcus Aureus, Endocarditis, Neutropenia, Headache, Fibrinolytic Bleeding, Pulmonary Arterial Hypertension, CMV Retinitis, Hypertension, Chronic Kidney Diseases, Hyperaldosteronism, Hypokalemia, Heart Failure, Hemophilia, Heavy Menstrual Bleeding, Insomnia
Interventions
The POPS study is collecting PK data on children prescribed the following drugs of interest per standard of care:
Drug
Lead sponsor
Daniel Benjamin
Other
Eligibility
Up to 21 Years
Enrollment
3,520 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2019
U.S. locations
43
States / cities
Anchorage, Alaska • Little Rock, Arkansas • La Jolla, California + 37 more
Source: ClinicalTrials.gov public record
Updated Sep 5, 2023 · Synced Sep 17, 2026, 4:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comparison of Deep Versus Awake Tracheal Extubation in Adults

NCT05361850
View directory record Official record
Conditions
Airway Complication of Anesthesia, Respiratory Complications of Care
Interventions
Extubation
Procedure
Lead sponsor
United States Navy
Federal
Eligibility
18 Years to 64 Years
Enrollment
220 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Portsmouth, Virginia
Source: ClinicalTrials.gov public record
Updated May 5, 2023 · Synced Sep 17, 2026, 4:40 AM EDT
Completed Phase 4 Interventional Results available

LIBERATE - LIposomal Bupivacaine vERsus Adjuncts in Total shouldErs

NCT03887650
View directory record Official record
Conditions
Post-operative Pain, Total Shoulder Arthroplasty, Osteoarthritis of the Shoulder, Pain Management
Interventions
Liposomal Bupivicaine 1.3%, Bupivacaine 0.5%
Drug
Lead sponsor
Hartford Hospital
Other
Eligibility
18 Years to 100 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 14, 2023 · Synced Sep 17, 2026, 4:40 AM EDT
Terminated No phase listed Observational

Electromyographic Assessment of Onset and Recovery of Neuromuscular Blockade

NCT01678625
View directory record Official record
Conditions
Residual Neuromuscular Blockade
Interventions
Train-of-four ratio calculation (T4-EMG)
Device
Lead sponsor
Endeavor Health
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Evanston, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 12, 2019 · Synced Sep 17, 2026, 4:40 AM EDT