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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Skin Prep Study

NCT01472549
Conditions
Surgical Site Infections
Interventions
Iodine-alcohol, Chlorhexidine-alcohol
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
Female only
Enrollment
1,147 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
1
States / cities
St Louis, Missouri
Completed Not applicable Interventional Accepts healthy volunteers Results available

STRIPES Study: Study To Reduce Infection Post cEsarean Section

NCT02402907
Conditions
Chlorhexidine Gluconate Cloths, Infection; Cesarean Section, Infectious Morbidity, Surgical Site Infections, Endometritis
Interventions
2% chlorhexidine gluconate (CHG) cloth, Placebo cloth
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older · Female only
Enrollment
1,356 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
New York, New York
Conditions
Cesarean Section, Surgical Site Infection, Nosocomial Infection
Interventions
2% chlorhexidine gluconate cloth, 4% Chlorhexidine gluconate vaginal scrub
Drug
Lead sponsor
Angela Bianco
Other
Eligibility
18 Years and older · Female only
Enrollment
319 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
New York, New York
Terminated Phase 4 Interventional Results available

Antibacterial-coated Sutures at Time of Cesarean

NCT03386240
Conditions
Surgical Site Infection, Surgical Wound Infection, Cesarean Section; Infection, Cesarean Section Complications
Interventions
Vicryl-plus, monocryl-plus, PDS-plus (Triclosan-coated Sutures), Vicryl, monocryl, PDS (not coated with triclosan)
Drug · Other
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
1,169 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Galveston, Texas
Completed Not applicable Interventional Accepts healthy volunteers Results available

Negative Pressure Wound Therapy in Cesarean Section

NCT02289157
Conditions
Postoperative Wound Complications
Interventions
Negative pressure wound therapy
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
10 Years to 64 Years · Female only
Enrollment
441 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Dallas, Texas
Conditions
High Risk Pregnancy, Cesarean Wound Disruption With Postnatal Complication
Interventions
PICO Single Use Negative Pressure Wound Therapy
Device
Lead sponsor
University of Arizona
Other
Eligibility
18 Years and older · Female only
Enrollment
154 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Tucson, Arizona
Conditions
Cesarean Section, Endometritis, Surgical Wound Infection
Interventions
Vaginal cleansing before cesarean delivery
Procedure
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older · Female only
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
3
States / cities
Indianapolis, Indiana
Conditions
Cesarean Section Complications, Cesarean Section; Infection
Interventions
Irrisept, Normal Saline
Device · Drug
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years and older · Female only
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Loma Linda, California
Withdrawn Not applicable Interventional Accepts healthy volunteers

Chlorhexidine Cloths to Reduce Surgical Site Infection in Cesarean Deliveries

NCT04202471
Conditions
Surgical Site Infection
Interventions
Chlorhexidine Cloth
Device
Lead sponsor
Northwell Health
Other
Eligibility
18 Years to 50 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Manhasset, New York
Completed Not applicable Interventional Results available

Negative Pressure Wound Therapy After Cesarean Delivery

NCT01637870
Conditions
Major Puerperal Infection, Postpartum, Wound Complications, Wound Seroma, Caesarean Section Wound Separation, Wound Infection
Interventions
Prevena negative pressure wound system
Device
Lead sponsor
Abbey Hardy-Fairbanks
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Iowa City, Iowa
Conditions
Wound Complications
Interventions
Glove change
Procedure
Lead sponsor
University of Minnesota
Other
Eligibility
Female only
Enrollment
554 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Saint Paul, Minnesota
Completed Not applicable Interventional Accepts healthy volunteers

Vaginal Cleansing Before Cesarean Delivery to Reduce Infection

NCT02495753
Conditions
Complications; Cesarean Section
Interventions
Vaginal Cleansing, Abdominal Cleansing
Procedure
Lead sponsor
Washington University School of Medicine
Other
Eligibility
Female only
Enrollment
608 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2021
U.S. locations
1
States / cities
St Louis, Missouri
Conditions
Cesarean Section Complications, Wound Infection
Interventions
Skin preparation patterns with ChloraPrep 2 x 26 mL single
Procedure
Lead sponsor
Albert Einstein Healthcare Network
Other
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Infection; Cesarean Section, Surgical Wound Infection, Endometritis
Interventions
80% inhaled oxygen via non-rebreather mask, 30% inhaled oxygen via nasal cannula
Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
12 Years to 50 Years · Female only
Enrollment
606 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
1
States / cities
St Louis, Missouri
Terminated Not applicable Interventional Accepts healthy volunteers

Vaginal Preparation and Azithromycin to Reduce Post Cesarean Infections

NCT04163679
Conditions
Infection, Obstetric Labor Complications, Endometritis, Cesarean Delivery Affecting Fetus, Wounds Injuries
Interventions
Vaginal Preparation
Procedure
Lead sponsor
Womack Army Medical Center
Federal
Eligibility
18 Years to 64 Years · Female only
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Fort Bragg, North Carolina
Conditions
Surgical Site Infection
Interventions
Chlorhexidine-alcohol group, Povidone-Iodine Group
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 45 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Terminated Not applicable Interventional Accepts healthy volunteers

Sutures vs. Staples Skin Closure After C-section in Obese Patients

NCT01820221
Conditions
Obesity, Pregnancy
Interventions
Suture vs. staples closure method after c-section in obese women.
Procedure
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
148 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Little Rock, Arkansas
Conditions
Wound Infection, Complication, Postoperative
Interventions
Povidone Iodine, Chlorhexidine gluconate
Procedure
Lead sponsor
Richmond University Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
1,114 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Staten Island, New York
Conditions
Surgical Site Infection, Cesarean Section; Complications, Wound, Infection (Following Delivery), Postpartum Complication
Interventions
Steri3X, Control
Device · Other
Lead sponsor
University of Tennessee
Other
Eligibility
16 Years and older · Female only
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Memphis, Tennessee
Conditions
Pain, Postoperative, Anesthesia, Local, Opioid Use
Interventions
Bupivacaine, Dexmedetomidine, Placebo
Drug
Lead sponsor
Richmond University Medical Center
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
540 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Staten Island, New York
Conditions
Bupivacaine, Pain, Postoperative
Interventions
Bupivacaine, Liposomal bupivacaine, Placebos
Drug
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
18 Years and older · Female only
Enrollment
132 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Fort Sam Houston, Texas
Conditions
Pregnancy
Interventions
Not listed
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 45 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Preventing Adverse Incisional Outcomes at Cesarean Multicenter Trial

NCT03009110
Conditions
Surgical Wound Infection, Cesarean Section
Interventions
Prophylactic NPWT, Standard Dressing
Device
Lead sponsor
Indiana University
Other
Eligibility
16 Years and older · Female only
Enrollment
1,624 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
6
States / cities
Birmingham, Alabama • Indianapolis, Indiana • New Orleans, Louisiana + 1 more
Conditions
Surgical Site Infection, Cesarean Section; Infection
Interventions
Abdominal Closure Bundle
Procedure
Lead sponsor
Abington Memorial Hospital
Other
Eligibility
18 Years and older · Female only
Enrollment
850 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Abington, Pennsylvania