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ClinicalTrials.gov public records Last synced Oct 6, 2026, 5:28 AM EDT

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Showing 73–96 of 194 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Complications; Cesarean Section Clear all
Withdrawn No phase listed Observational

The Use of the Prevena Incision Management System to Reduce Post-operative Cesarean Delivery Wound Complications

NCT01661348
View directory record Official record
Conditions
Pregnancy
Interventions
Not listed
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 45 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Oct 16, 2013 · Synced Oct 6, 2026, 5:28 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

DAISY Uterine Drain Device Evaluation

NCT06219538
View directory record Official record
Conditions
Cesarean Section Complications, Post Partum Hemorrhage, Uterine Atony With Hemorrhage, Uterine Bleeding
Interventions
DAISY Uterine Drain
Device
Lead sponsor
Raydiant Oximetry, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Norfolk, Virginia
Source: ClinicalTrials.gov public record
Updated May 1, 2026 · Synced Oct 6, 2026, 5:28 AM EDT
Withdrawn Early Phase 1 Interventional Accepts healthy volunteers

Intravenous Versus Intramuscular Administration of Methylergonovine for Uterine Contraction in Cesarean Sections

NCT03303235
View directory record Official record
Conditions
Uterine Atony, Uterine Tone Disorders, Postpartum Hemorrhage
Interventions
Methylergonovine
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 3, 2020 · Synced Oct 6, 2026, 5:28 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Pharmacokinetics of Oxytocin at Cesarean Delivery

NCT03898882
View directory record Official record
Conditions
Postpartum Hemorrhage
Interventions
oxytocin, Shore durometer
Drug · Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated May 7, 2020 · Synced Oct 6, 2026, 5:28 AM EDT
Terminated Phase 2 Interventional Results available

Preoperative Application of Chlorhexidine to Reduce Infection With Cesarean Section After Labor

NCT03423147
View directory record Official record
Conditions
Cesarean Section, Surgical Site Infection, Nosocomial Infection
Interventions
2% chlorhexidine gluconate cloth, 4% Chlorhexidine gluconate vaginal scrub
Drug
Lead sponsor
Angela Bianco
Other
Eligibility
18 Years and older · Female only
Enrollment
319 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 23, 2023 · Synced Oct 6, 2026, 5:28 AM EDT
Terminated Not applicable Interventional Results available

Use of Negative Pressure Wound Therapy in Morbidly Obese Women After Cesarean Delivery

NCT03269968
View directory record Official record
Conditions
Obesity, Morbid, Wound Infection, Wound Complication
Interventions
Negative pressure wound therapy (PREVENA Incision Management Therapy System), Standard dressing
Device
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Oct 19, 2020 · Synced Oct 6, 2026, 5:28 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Skin Incisions and Wound Complication Rates for C-sections in Obese Women

NCT02685761
View directory record Official record
Conditions
Obesity, Infection; Cesarean Section, Surgical Wound
Interventions
Midline Vertical, High Transverse
Procedure
Lead sponsor
Albany Medical College
Other
Eligibility
Female only
Enrollment
309 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2021
U.S. locations
6
States / cities
Albany, New York • Ballston Spa, New York • Clifton Park, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 13, 2016 · Synced Oct 6, 2026, 5:28 AM EDT
Terminated Not applicable Interventional Results available

Prevention of Wound Complications After Cesarean Delivery in Obese Women Utilizing Negative Pressure Wound Therapy

NCT00654641
View directory record Official record
Conditions
Surgical Wound Dehiscence, Wound Infection
Interventions
Negative pressure wound closure, Standard wound closure
Procedure
Lead sponsor
West Virginia University
Other
Eligibility
18 Years and older · Female only
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
2
States / cities
Charleston, West Virginia • Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated Jan 30, 2013 · Synced Oct 6, 2026, 5:28 AM EDT
Completed No phase listed Observational

Arm and Ankle Blood Pressure Cuffs During C-Section

NCT04934995
View directory record Official record
Conditions
Supine Hypotensive Syndrome, Cesarean Section Complications, Anesthesia Complication
Interventions
Blood Pressure Cuff
Other
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 21, 2024 · Synced Oct 6, 2026, 5:28 AM EDT
Completed Phase 4 Interventional Results available

IV Acetaminophen for Acute Post Operative Pain in C-Section Patients

NCT02069184
View directory record Official record
Conditions
Post-operative Pain
Interventions
IV Acetaminophen, Saline as placebo
Drug · Other
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Aug 22, 2019 · Synced Oct 6, 2026, 5:28 AM EDT
Terminated Phase 4 Interventional Results available

Antibacterial-coated Sutures at Time of Cesarean

NCT03386240
View directory record Official record
Conditions
Surgical Site Infection, Surgical Wound Infection, Cesarean Section; Infection, Cesarean Section Complications
Interventions
Vicryl-plus, monocryl-plus, PDS-plus (Triclosan-coated Sutures), Vicryl, monocryl, PDS (not coated with triclosan)
Drug · Other
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
1,169 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 22, 2026 · Synced Oct 6, 2026, 5:28 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Ketamine to Improve Recovery After Cesarean Delivery - Part 1

NCT04037085
View directory record Official record
Conditions
Obstetric Pain, Postpartum Depression, Breastfeeding, Pain, Acute, Pain, Chronic, Obstetric Anesthesia Problems, Drug Effect, Opioid Use
Interventions
Ketamine
Drug
Lead sponsor
Grace Lim, MD, MS
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 20, 2022 · Synced Oct 6, 2026, 5:28 AM EDT
Terminated Phase 3 Interventional Accepts healthy volunteers Results available

Propranolol Rescue of Prolonged Labor

NCT04299438
View directory record Official record
Conditions
Pregnancy, Prolonged
Interventions
Propranolol Hydrochloride, Saline
Drug · Other
Lead sponsor
Lisa Levine
Other
Eligibility
16 Years and older · Female only
Enrollment
164 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
2
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 23, 2023 · Synced Oct 6, 2026, 5:28 AM EDT
Completed No phase listed Observational

Transfusion of Whole Blood and Cesarean Delivery: A Retrospective Review

NCT03523780
View directory record Official record
Conditions
Obstetric Labor Complications
Interventions
Not listed
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
1,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated May 19, 2020 · Synced Oct 6, 2026, 5:28 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Ketamine Tolerated Dose for Postpartum Depression and Pain After Cesarean Delivery (PREPARE 1)

NCT05907213
View directory record Official record
Conditions
Pain, Postoperative, Depression, Postpartum
Interventions
Ketamine (Ketalar) Dose Level 1, Ketamine (Ketalar) Dose Level 2, Ketamine (Ketalar) Dose Level 3, Ketamine (Ketalar) Dose Level 4
Drug
Lead sponsor
Grace Lim, MD, MS
Other
Eligibility
18 Years and older · Female only
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 12, 2025 · Synced Oct 6, 2026, 5:28 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

PROphylactic Wound VACuum Therapy to Decrease Rates of Cesarean Section in the Obese Population

NCT02128997
View directory record Official record
Conditions
Wound Complication
Interventions
Closed incision wound vacuum (Prevena)
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
136 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 13, 2017 · Synced Oct 6, 2026, 5:28 AM EDT
Completed Not applicable Interventional

The Effect of Timing of Removal of Wound Dressing on Surgical Site Infection Rate After Cesarean Delivery

NCT02902419
View directory record Official record
Conditions
Surgical Site Infection
Interventions
Wound dressing removal.
Other
Lead sponsor
Albany Medical College
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
602 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
2
States / cities
Albany, New York • Niskayuna, New York
Source: ClinicalTrials.gov public record
Updated Sep 15, 2016 · Synced Oct 6, 2026, 5:28 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Cervical Ripening in Premature Rupture of Membranes

NCT02314728
View directory record Official record
Conditions
Pregnancy, Premature Rupture of Membranes, Preterm Premature Rupture of Membranes, Unfavorable Cervix
Interventions
Misoprostol, Oxytocin
Drug
Lead sponsor
Montefiore Medical Center
Other
Eligibility
15 Years to 50 Years · Female only
Enrollment
230 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Aug 10, 2021 · Synced Oct 6, 2026, 5:28 AM EDT
Completed Phase 4 Interventional Results available

Transverse Abdominis Plane (TAP) Block After Cesarean Delivery

NCT01170702
View directory record Official record
Conditions
Postoperative Pain, Pregnancy, Obesity
Interventions
0.9% Normal Saline, 0.2% Ropivacaine, 0.5% Ropivacaine, 0.75% Ropivacaine
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older · Female only
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 8, 2021 · Synced Oct 6, 2026, 5:28 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Prophylactic DR-CPAP on Late Preterm Infants Born by C-section: an RCT

NCT05204719
View directory record Official record
Conditions
Premature Birth
Interventions
Prophylactic Delivery Room Continuous Positive Airway Pressure
Procedure
Lead sponsor
University of Oklahoma
Other
Eligibility
1 Minute to 5 Minutes
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
3
States / cities
Indianapolis, Indiana • St Louis, Missouri • Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Oct 6, 2026, 5:28 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Timing of Prophylactic Antibiotics for Cesarean Sections

NCT00330278
View directory record Official record
Conditions
Endometritis, Wound Infection
Interventions
Cefazolin
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older · Female only
Enrollment
350 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2006
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 27, 2007 · Synced Oct 6, 2026, 5:28 AM EDT
Completed Phase 2 Interventional

HTX-011 Administration Study in Planned Caesarean Section Procedure

NCT03955211
View directory record Official record
Conditions
Analgesia
Interventions
HTX-011, Luer Lock Applicator, Ibuprofen, Acetaminophen
Drug · Device
Lead sponsor
Heron Therapeutics
Industry
Eligibility
18 Years and older · Female only
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
4
States / cities
Sheffield, Alabama • San Diego, California • Durham, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 14, 2022 · Synced Oct 6, 2026, 5:28 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Reduction of Endometritis After Cesarean Section With the Routine Use of Methergine

NCT00858832
View directory record Official record
Conditions
Endometritis
Interventions
Methergine
Drug
Lead sponsor
University of South Florida
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2011
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Sep 19, 2012 · Synced Oct 6, 2026, 5:28 AM EDT
Recruiting Not applicable Interventional

Wound Irrigation With Saline Versus Hypodilute-chlorhexidine After Cesarean Section (WISHES Study)

NCT06339203
View directory record Official record
Conditions
Cesarean Section Complications, Cesarean Section; Infection
Interventions
Irrisept, Normal Saline
Device · Drug
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years and older · Female only
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Oct 6, 2026, 5:28 AM EDT