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ClinicalTrials.gov public records Last synced Oct 9, 2026, 5:02 PM EDT

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Showing 145–168 of 1,850 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Complications Surgical Clear all
Completed Phase 1 Interventional

A Phase I Study of Intraperitoneal Hyperthermic Docetaxel

NCT00474669
View directory record Official record
Conditions
Ovarian Carcinoma
Interventions
docetaxel
Drug
Lead sponsor
University of Louisville
Other
Eligibility
19 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Jan 9, 2018 · Synced Oct 9, 2026, 5:02 PM EDT
Recruiting Phase 1Phase 2 Interventional

CATALINA-4: A Study to Investigate the Safety and Efficacy of TORL-1-23 With Chemotherapy Given Before Initial Surgery in Women With Advanced Stage Ovarian Cancer

NCT07322094
View directory record Official record
Conditions
FIGO Stage III and IV Ovarian Cancer, Fallopian Tube Cancers, Primary Peritoneal Cancer
Interventions
TORL-1-23 and paclitaxel, TORL-1-23 and carboplatin, TORL-1-23, paclitaxel, and carboplatin
Combination Product
Lead sponsor
TORL Biotherapeutics, LLC
Industry
Eligibility
18 Years to 75 Years · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
7
States / cities
Fullerton, California • Irvine, California • Los Angeles, California + 3 more
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Oct 9, 2026, 5:02 PM EDT
Completed Phase 3 Interventional

Comparison of the Safety of Q8003 Versus Morphine Equivalent Doses of Its Components (Oxycodone and Morphine) in Bunionectomy Patients

NCT01280331
View directory record Official record
Conditions
Postoperative Pain
Interventions
Q8003 (morphine sulfate and oxycodone hydrochloride), Morphine sulfate, Oxycodone HCl
Drug
Lead sponsor
QRxPharma Inc.
Industry
Eligibility
18 Years and older
Enrollment
375 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
4
States / cities
Anaheim, California • Owings Mills, Maryland • Pasadena, Maryland + 1 more
Source: ClinicalTrials.gov public record
Updated May 17, 2012 · Synced Oct 9, 2026, 5:02 PM EDT
Completed Phase 4 Interventional Results available

Sugammadex To IMprove Bowel Function

NCT04546672
View directory record Official record
Conditions
Bowel Dysfunction, Postoperative Complications, Neuromuscular Blockade
Interventions
Sugammadex, Neostigmine
Drug
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jul 29, 2024 · Synced Oct 9, 2026, 5:02 PM EDT
Completed Not applicable Interventional

Preoperative Guided Imagery in Patients Undergoing Urologic Surgery

NCT05072639
View directory record Official record
Conditions
Urologic Cancer
Interventions
Guided Meditation
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
123 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 22, 2021 · Synced Oct 9, 2026, 5:02 PM EDT
Enrolling by invitation Phase 4 Interventional

Suzetrigine for Non-Mastectomy Breast Surgery

NCT07463430
View directory record Official record
Conditions
Pain, Acute Postoperative, Breast Disease
Interventions
suzetrigine
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Sep 16, 2026 · Synced Oct 9, 2026, 5:02 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Temporary Autonomic Blockade to Prevent Atrial Fibrillation After Cardiac Surgery

NCT02498769
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Botulinum Toxin Type A, Placebo
Drug
Lead sponsor
Joseph Mathew, M.D.
Other
Eligibility
50 Years to 90 Years
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 22, 2019 · Synced Oct 9, 2026, 5:02 PM EDT
Completed Phase 2 Interventional

Study of Indomethacin Capsules to Treat Pain Following Surgery in Children Ages 6 to <17 Years of Age

NCT02633969
View directory record Official record
Conditions
Pain, Postoperative
Interventions
Indomethacin Capsules low dose, Indomethacin Capsules high dose
Drug
Lead sponsor
Iroko Pharmaceuticals, LLC
Industry
Eligibility
6 Years to 16 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
5
States / cities
Sheffield, Alabama • Aurora, Colorado • Coral Gables, Florida + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 26, 2018 · Synced Oct 9, 2026, 5:02 PM EDT
Completed Early Phase 1 Interventional

IV Tranexamic Acid Prior to Hysterectomy

NCT02911831
View directory record Official record
Conditions
Hysterectomy, Blood Loss, Surgical
Interventions
Tranexamic Acid, Sodium Chloride
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older · Female only
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 9, 2022 · Synced Oct 9, 2026, 5:02 PM EDT
Completed Not applicable Interventional

Evaluating the Optimal Volume Voided for Passage of a Backfill-Assisted Voiding Trial Following Urogynecologic Surgery

NCT05820139
View directory record Official record
Conditions
Voiding Dysfunction
Interventions
Control Group, Test Group
Procedure
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 29, 2024 · Synced Oct 9, 2026, 5:02 PM EDT
Completed Phase 3 Interventional

Double-Blind, Randomized Study Of The Analgesic Efficacy And Safety Of Valdecoxib 20 Mg Daily And Valdecoxib 20 Mg Twice Daily Compared To Placebo For Management Of Acute Postsurgical Pain In Anterior Cruciate Ligament (ACL) Reconstruction

NCT00650039
View directory record Official record
Conditions
Pain
Interventions
placebo, valdecoxib
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 75 Years
Enrollment
488 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
68
States / cities
Birmingham, Alabama • Northport, Alabama • Glendale, Arizona + 46 more
Source: ClinicalTrials.gov public record
Updated Jun 4, 2008 · Synced Oct 9, 2026, 5:02 PM EDT
Terminated Not applicable Interventional

TSA Exercise Prehabilitation in Older Adults

NCT03212300
View directory record Official record
Conditions
Postoperative Delirium and Delayed Functional Recovery
Interventions
Aerobic Exercise Training (AET)
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
55 Years to 75 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 14, 2020 · Synced Oct 9, 2026, 5:02 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Methadone for Emergence Delirium in Children Undergoing Outpatient Strabismus Surgery

NCT03778372
View directory record Official record
Conditions
Emergence Delirium, Strabismus
Interventions
Methadone
Drug
Lead sponsor
Ochsner Health System
Other
Eligibility
0 Years to 18 Years
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Jefferson, Louisiana
Source: ClinicalTrials.gov public record
Updated Jul 19, 2022 · Synced Oct 9, 2026, 5:02 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

iPAWS: Improving Pain Management After Wisdom Tooth Extraction Surgery

NCT07731295
View directory record Official record
Conditions
Pain, Postoperative, Substance Use
Interventions
iPAWS, Educational Materials
Behavioral · Other
Lead sponsor
Brown University
Other
Eligibility
15 Years to 20 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 28, 2026 · Synced Oct 9, 2026, 5:02 PM EDT
Completed Not applicable Interventional Results available

Comparison of Two Naloxone Infusion Rates on the Postoperative Recovery of Patients Undergoing Spine Fusion Surgery

NCT01531439
View directory record Official record
Conditions
Pain, Postoperative, Postoperative Nausea and Vomiting, Scoliosis
Interventions
Naloxone
Drug
Lead sponsor
Children's Mercy Hospital Kansas City
Other
Eligibility
10 Years to 21 Years
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 10, 2020 · Synced Oct 9, 2026, 5:02 PM EDT
Completed Not applicable Interventional

Efficacy of Aquamantys for Reducing Transfusions With Anterior Supine Intermuscular Approach Total Hip Arthroplasty

NCT01583465
View directory record Official record
Conditions
Osteoarthritis, Hip, Joint Deformities, Acquired, Hip Dislocation, Congenital, Osteonecrosis, Arthritis, Rheumatoid
Interventions
Aquamantys, standard electrocautery (Bovie)
Device
Lead sponsor
Joint Implant Surgeons, Inc.
Other
Eligibility
Not listed
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
New Albany, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 24, 2012 · Synced Oct 9, 2026, 5:02 PM EDT
Not yet recruiting Phase 1 Interventional

Simultaneous Engagement of Networks for Alleviating Pain (SENAP)

NCT07057206
View directory record Official record
Conditions
Neuropathic Pain, Postherpetic Neuralgia
Interventions
PFM-guided cortical stimulation
Device
Lead sponsor
University of Minnesota
Other
Eligibility
22 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 23, 2026 · Synced Oct 9, 2026, 5:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Robotic Surgical Management of Endometriosis: Excision Versus Ablation

NCT02350790
View directory record Official record
Conditions
Endometriosis
Interventions
Robotic ablation, Robotic excision
Procedure
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
73 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 23, 2017 · Synced Oct 9, 2026, 5:02 PM EDT
Completed Phase 4 Interventional

Tranexamic Acid for Total Knee Arthroscopy

NCT04443920
View directory record Official record
Conditions
Blood Loss, Surgical
Interventions
Tranexamic acid (TXA), Placebo Normal Saline (NS)
Drug
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years and older
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jun 22, 2023 · Synced Oct 9, 2026, 5:02 PM EDT
Active, not recruiting No phase listed Observational

Building a Platform for Precision Anesthesia in the Geriatric Surgical Patient

NCT03839784
View directory record Official record
Conditions
Cognitive Decline, Cognitive Change, Cognitive Impairment, Postoperative Delirium, Anesthesia; Reaction, Anesthesia; Adverse Effect
Interventions
Neurocognition Interventions
Combination Product
Lead sponsor
Stanford University
Other
Eligibility
65 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2030
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Apr 23, 2026 · Synced Oct 9, 2026, 5:02 PM EDT
Recruiting Phase 4 Interventional

Decolonization to Reduce After-Surgery Events of Surgical Site Infection

NCT05586776
View directory record Official record
Conditions
Surgical Site Infection
Interventions
4% Chlorhexidine Gluconate, 2% Mupirocin, Soap Without Antiseptic Properties (Placebo), Placebo Nasal Ointment
Drug
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Enrollment
2,700 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
4
States / cities
Newport Beach, California • Orange, California • Sacramento, California + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Oct 9, 2026, 5:02 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Evaluation of Local Anesthetic at Incision Site

NCT02483689
View directory record Official record
Conditions
Post Operative Pain, Appendicitis
Interventions
Pre Incisional Local Anesthetic, Pre-Incisional Saline, Post-Closure Local Anesthetic, Post-Closure Saline
Drug · Other
Lead sponsor
Valley Anesthesiology Consultants
Other
Eligibility
9 Years to 17 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2020
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated May 2, 2018 · Synced Oct 9, 2026, 5:02 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Intraoperative OCT Guidance of Intraocular Surgery II

NCT03713268
View directory record Official record
Conditions
Macular Holes, Epiretinal Membrane, Diabetic Retinopathy, Retinal Detachment, Retinal Disease, Preretinal Fibrosis, Cataract, Ocular Tumor, Strabismus, Healthy
Interventions
Microscope integrated optical coherence tomography
Device
Lead sponsor
Duke University
Other
Eligibility
4 Weeks and older
Enrollment
262 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 6, 2025 · Synced Oct 9, 2026, 5:02 PM EDT
Active, not recruiting Phase 2 Interventional

A Trial of Vigil for Participants With Ovarian Cancer

NCT02346747
View directory record Official record
Conditions
Ovarian Cancer, Ovarian Neoplasms
Interventions
Vigil, Placebo
Biological · Other
Lead sponsor
Gradalis, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2028
U.S. locations
26
States / cities
Mobile, Alabama • Irvine, California • San Francisco, California + 22 more
Source: ClinicalTrials.gov public record
Updated Oct 29, 2025 · Synced Oct 9, 2026, 5:02 PM EDT